BLASTX 7.6.2
Query= UN44052 /QuerySize=973
(972 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorh... 100 2e-020
sp|P45478|PPT1_BOVIN Palmitoyl-protein thioesterase 1 OS=Bos tau... 84 1e-015
sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyos... 83 2e-015
sp|P45479|PPT1_RAT Palmitoyl-protein thioesterase 1 OS=Rattus no... 82 4e-015
sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS=Homo sa... 82 5e-015
sp|Q8HXW6|PPT1_MACFA Palmitoyl-protein thioesterase 1 OS=Macaca ... 82 5e-015
sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus mus... 81 1e-014
sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus l... 74 1e-012
sp|Q9W3C7|PPT1_DROME Palmitoyl-protein thioesterase 1 OS=Drosoph... 65 8e-010
>sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorhabditis elegans
GN=ppt-1 PE=2 SV=2
Length = 298
Score = 100 bits (248), Expect = 2e-020
Identities = 49/132 (37%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
Frame = -2
Query: 503 IPKCSDHIAPSGFVKIPGEMTKYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMF 324
+P + + + P ++ +Y S +L +NNE + N T+K +SL NLVLV F
Sbjct: 164 LPFVQKRVVQAQYWHDPNQVEEYKKRSIFLADINNE--NNNNPTYKRNLLSLKNLVLVKF 221
Query: 323 QNDTTLIPKETSWFGYYSDDGFDSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHL 144
D ++PK++SWFG+Y D D++L +T LY+ED IGLK L G++ F+ V GDHL
Sbjct: 222 NQDHMVVPKDSSWFGFYKDGDIDTILPMNETDLYKEDRIGLKKLHESGRIHFMDVDGDHL 281
Query: 143 MISYKDVVKYVV 108
I +V ++
Sbjct: 282 QIPRSVLVNDII 293
>sp|P45478|PPT1_BOVIN Palmitoyl-protein thioesterase 1 OS=Bos taurus GN=PPT1
PE=1 SV=1
Length = 306
Score = 84 bits (207), Expect = 1e-015
Identities = 39/113 (34%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
Frame = -2
Query: 437 YLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDGF 258
Y HS +L +N ER N ++K ++L V+V F NDT + P ++ WFG+Y
Sbjct: 195 YRNHSIFLADINQER--GVNESYKKNLMALKKFVMVKFLNDTIVDPVDSEWFGFYRSGQA 252
Query: 257 DSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYL 99
+ Q++ LY +D +GLKA+D G++ F+++ GDHL +S + +++P+L
Sbjct: 253 KETIPLQESTLYTQDRLGLKAMDKAGQLVFLALEGDHLQLSEEWFYAHIIPFL 305
Score = 68 bits (164), Expect = 1e-010
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 11/128 (8%)
Frame = -2
Query: 833 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 675
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIHVLSLEIGKTLREDVENSFFLNVNSQV 92
Query: 674 SLACEKVKMMKELSQGYNIVAQSQGNLVARGLIEFCDDAPPLTNYVSLGGPHAGISAIPK 495
+ C+ + +L QGYN + SQG R + + C +PP+ N +S+GG H G+ +P+
Sbjct: 93 TTVCQILAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMVNLISVGGQHQGVFGLPR 151
Query: 494 C---SDHI 480
C S HI
Sbjct: 152 CPGESSHI 159
>sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyostelium
discoideum GN=ppt3 PE=3 SV=1
Length = 289
Score = 83 bits (204), Expect = 2e-015
Identities = 44/126 (34%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -2
Query: 461 KIPGEMTKYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWF 282
K P + KYL S +L +NNE +N+T+K+ L+ +VL ND T+IPKE+ WF
Sbjct: 163 KDPHRIDKYLERSIFLADINNEY-QVKNTTYKENLTKLNAMVLTYSTNDKTIIPKESGWF 221
Query: 281 GYYSDDGFDSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVK----- 117
+Y+D ++ QQ Y EDW+GL+ LD ++ F + + H +D K
Sbjct: 222 SFYADGSGTEVVPLQQQTQYSEDWLGLRTLDESNRLFFYTTTCTHRDHPIEDYCKPYFTN 281
Query: 116 YVVPYL 99
+ +PYL
Sbjct: 282 FTLPYL 287
Score = 58 bits (138), Expect = 1e-007
Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 26/163 (15%)
Frame = -2
Query: 893 VLLLTVATVLLFSTVPVSNSIPFILFHGIGDKCSGGVSNFTQLLSNLSGSPGSC----LE 726
+LL+ +A L+ +T PV +L HG+ + G + L S + S +E
Sbjct: 8 ILLIALAIALVSATRPV------VLMHGV----TTGKESMEPLKSWIEESIPDIYVLNVE 57
Query: 725 IGNGETDSWFMPLTQQTSLACEKVKMMKELSQGYNIVAQSQGNLVARGLIEFCDDAPPLT 546
IGNG DS F + Q + V+ +L+ G+N++ SQG L+AR ++ ++ P +
Sbjct: 58 IGNGAFDSIFTTMDSQIEEFAQVVQADPKLANGFNLIGFSQGTLIARAFVQRYNN-PQVY 116
Query: 545 NYVSLGGPHAGISAIPKCSDHIAPSGFVKIPGEMTKYLGHSKY 417
NY+S GP G P FV IP + K LG Y
Sbjct: 117 NYISWNGPQGGQFGTP----------FVNIPW-VDKVLGTIPY 148
>sp|P45479|PPT1_RAT Palmitoyl-protein thioesterase 1 OS=Rattus norvegicus
GN=Ppt1 PE=1 SV=1
Length = 306
Score = 82 bits (202), Expect = 4e-015
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -2
Query: 437 YLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDGF 258
Y S +L +N ER N ++K+ ++L V+V F ND+ + P ++ WFG+Y
Sbjct: 195 YRNCSIFLADINQER--HINESYKENLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQA 252
Query: 257 DSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYL 99
+ Q+T LY ED +GLK +D GK+ F++ GDHL IS + +++P+L
Sbjct: 253 KETIPLQETTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFL 305
>sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS=Homo sapiens GN=PPT1
PE=1 SV=1
Length = 306
Score = 82 bits (201), Expect = 5e-015
Identities = 38/113 (33%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -2
Query: 437 YLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDGF 258
Y HS +L +N ER N ++K ++L V+V F ND+ + P ++ WFG+Y
Sbjct: 195 YRNHSIFLADINQER--GINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQA 252
Query: 257 DSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYL 99
+ Q+T LY +D +GLK +D G++ F++ GDHL +S + +++P+L
Sbjct: 253 KETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFL 305
Score = 68 bits (164), Expect = 1e-010
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 11/128 (8%)
Frame = -2
Query: 833 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 675
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQV 92
Query: 674 SLACEKVKMMKELSQGYNIVAQSQGNLVARGLIEFCDDAPPLTNYVSLGGPHAGISAIPK 495
+ C+ + +L QGYN + SQG R + + C +PP+ N +S+GG H G+ +P+
Sbjct: 93 TTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMINLISVGGQHQGVFGLPR 151
Query: 494 C---SDHI 480
C S HI
Sbjct: 152 CPGESSHI 159
>sp|Q8HXW6|PPT1_MACFA Palmitoyl-protein thioesterase 1 OS=Macaca fascicularis
GN=PPT1 PE=2 SV=1
Length = 306
Score = 82 bits (201), Expect = 5e-015
Identities = 38/113 (33%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -2
Query: 437 YLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDGF 258
Y HS +L +N ER N ++K ++L V+V F ND+ + P ++ WFG+Y
Sbjct: 195 YRNHSIFLADINQER--GINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQA 252
Query: 257 DSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYL 99
+ Q+T LY +D +GLK +D G++ F++ GDHL +S + +++P+L
Sbjct: 253 KETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFL 305
Score = 68 bits (164), Expect = 1e-010
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 11/128 (8%)
Frame = -2
Query: 833 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 675
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQV 92
Query: 674 SLACEKVKMMKELSQGYNIVAQSQGNLVARGLIEFCDDAPPLTNYVSLGGPHAGISAIPK 495
+ C+ + +L QGYN + SQG R + + C +PP+ N +S+GG H G+ +P+
Sbjct: 93 TTVCQTLAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMINLISVGGQHQGVFGLPR 151
Query: 494 C---SDHI 480
C S HI
Sbjct: 152 CPGESSHI 159
>sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus musculus GN=Ppt1
PE=2 SV=2
Length = 306
Score = 81 bits (198), Expect = 1e-014
Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%)
Frame = -2
Query: 455 PGEMTKYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGY 276
P + + Y +S +L +N ER N ++K ++L V+V F ND+ + P ++ WFG+
Sbjct: 189 PIKESVYRNYSIFLADINQER--CVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGF 246
Query: 275 YSDDGFDSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYL 99
Y + Q++ LY ED +GLK +D GK+ F++ GDHL IS + +++P+L
Sbjct: 247 YRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFL 305
Score = 66 bits (160), Expect = 3e-010
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 11/127 (8%)
Frame = -2
Query: 830 PFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIGNGETD----SWFMPLTQQTS 672
P +++HG+GD C +S + + G LEIG + S+F+ + Q +
Sbjct: 34 PLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVN 93
Query: 671 LACEKVKMMKELSQGYNIVAQSQGNLVARGLIEFCDDAPPLTNYVSLGGPHAGISAIPKC 492
+ C+ ++ +L QGYN + SQG R + + C PP+ +S+GG H G+ +P+C
Sbjct: 94 MVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRC-PTPPMMTLISVGGQHQGVFGLPRC 152
Query: 491 ---SDHI 480
S HI
Sbjct: 153 PGESSHI 159
>sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus laevis GN=ppt2-b
PE=2 SV=1
Length = 288
Score = 74 bits (180), Expect = 1e-012
Identities = 45/138 (32%), Positives = 74/138 (53%), Gaps = 7/138 (5%)
Frame = -2
Query: 551 LTNYVSLGGPHAGISAIP-----KCSDHIAPSGFVKIPGEMTKYLGHSKYLPKLNNERPD 387
+T YV P ISA+ K I+ G+ + P KYL +S +LPKLNNE D
Sbjct: 131 MTLYVQKALPLVNISALQEVCYRKFFKEISICGYWRDPHRYEKYLEYSAFLPKLNNELLD 190
Query: 386 QRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDGFDSLLSTQQTKLYREDWI 207
++ K F+ L LVL+ +D + P ++S FG+Y++ + +++ + +Y++D
Sbjct: 191 SNSTERKRNFLRLRKLVLIGGPDDEVIAPWQSSHFGFYNEK--EEVVNMKDQMVYQKDTF 248
Query: 206 GLKALDAVGKVKFVSVSG 153
GL++LD G + SV G
Sbjct: 249 GLQSLDGRGAITIYSVPG 266
>sp|Q9W3C7|PPT1_DROME Palmitoyl-protein thioesterase 1 OS=Drosophila
melanogaster GN=Ppt1 PE=1 SV=2
Length = 314
Score = 65 bits (156), Expect = 8e-010
Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
Frame = -2
Query: 440 KYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVMFQNDTTLIPKETSWFGYYSDDG 261
KY S +L +NNE N + + L V+V F NDT + PKE+ WF YY+
Sbjct: 202 KYRLGSTFLADINNEL--FINKFYIENLQKLKKFVMVQFLNDTIVQPKESQWFQYYTTGQ 259
Query: 260 FDSLLSTQQTKLYREDWIGLKALDAVGKVKFVSVSGDHLMISYKDVVKYVVPYLMQ 93
+ ++K+Y++ +GL + G++ F+ V GDHL IS ++ +VP L++
Sbjct: 260 NKVIQPFTESKVYQD--LGLDKMHRQGQLVFLGVEGDHLAISKAWFIQNIVPLLLE 313
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167,919,208,508
Number of Sequences: 518415
Number of Extensions: 167919208508
Number of Successful Extensions: 1034094832
Number of sequences better than 0.0: 0
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