BLASTX 7.6.2
Query= UN44754 /QuerySize=686
(685 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O24617|MSH2_ARATH DNA mismatch repair protein Msh2 OS=Arabido... 317 7e-086
sp|Q9XGC9|MSH2_MAIZE DNA mismatch repair protein MSH2 OS=Zea may... 168 3e-041
sp|P25847|MSH2_YEAST DNA mismatch repair protein MSH2 OS=Sacchar... 109 2e-023
sp|O74773|MSH2_SCHPO DNA mismatch repair protein msh2 OS=Schizos... 94 7e-019
sp|O13396|MSH2_NEUCR DNA mismatch repair protein msh-2 OS=Neuros... 82 3e-015
sp|Q3MHE4|MSH2_BOVIN DNA mismatch repair protein Msh2 OS=Bos tau... 82 4e-015
sp|P43246|MSH2_HUMAN DNA mismatch repair protein Msh2 OS=Homo sa... 80 8e-015
sp|P43247|MSH2_MOUSE DNA mismatch repair protein Msh2 OS=Mus mus... 79 3e-014
sp|Q5XXB5|MSH2_CERAE DNA mismatch repair protein Msh2 OS=Cercopi... 78 4e-014
sp|P54275|MSH2_RAT DNA mismatch repair protein Msh2 OS=Rattus no... 76 2e-013
sp|Q553L4|MSH2_DICDI DNA mismatch repair protein Msh2 OS=Dictyos... 73 2e-012
sp|A7NPT5|MUTS_ROSCS DNA mismatch repair protein mutS OS=Roseifl... 60 9e-009
sp|A5UZK7|MUTS_ROSS1 DNA mismatch repair protein mutS OS=Roseifl... 60 9e-009
sp|C5D9H5|MUTS_GEOSW DNA mismatch repair protein mutS OS=Geobaci... 57 1e-007
sp|A9VS13|MUTS_BACWK DNA mismatch repair protein mutS OS=Bacillu... 56 2e-007
sp|C3P5H5|MUTS_BACAA DNA mismatch repair protein mutS OS=Bacillu... 55 4e-007
sp|C3L822|MUTS_BACAC DNA mismatch repair protein mutS OS=Bacillu... 55 4e-007
sp|A0RHE1|MUTS_BACAH DNA mismatch repair protein mutS OS=Bacillu... 55 4e-007
sp|Q81WR3|MUTS_BACAN DNA mismatch repair protein mutS OS=Bacillu... 55 4e-007
sp|B7JJ47|MUTS_BACC0 DNA mismatch repair protein mutS OS=Bacillu... 55 4e-007
>sp|O24617|MSH2_ARATH DNA mismatch repair protein Msh2 OS=Arabidopsis thaliana
GN=MSH2 PE=2 SV=1
Length = 937
Score = 317 bits (810), Expect = 7e-086
Identities = 158/180 (87%), Positives = 166/180 (92%), Gaps = 6/180 (3%)
Frame = -3
Query: 683 GLAWAICEHLVQVKKAPTLFATHFHELTALAQANSEVAGNTVGVANFHVSAHIDTESRKL 504
GLAWAICEHLVQVK+APTLFATHFHELTALAQANSEV+GNTVGVANFHVSAHIDTESRKL
Sbjct: 758 GLAWAICEHLVQVKRAPTLFATHFHELTALAQANSEVSGNTVGVANFHVSAHIDTESRKL 817
Query: 503 TMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSP------REESGKRKS 342
TMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSP EESGKRKS
Sbjct: 818 TMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPSSMIINNEESGKRKS 877
Query: 341 REDDAEEVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDELEKDAVDCHWLKQVL 162
REDD +EVSRG RAHKFLKEFA IP+DKMELKDSL+R+ E+KDELEKDA DCHWL+Q L
Sbjct: 878 REDDPDEVSRGAERAHKFLKEFAAIPLDKMELKDSLQRVREMKDELEKDAADCHWLRQFL 937
>sp|Q9XGC9|MSH2_MAIZE DNA mismatch repair protein MSH2 OS=Zea mays GN=MUS1 PE=3
SV=1
Length = 942
Score = 168 bits (425), Expect = 3e-041
Identities = 83/106 (78%), Positives = 92/106 (86%), Gaps = 2/106 (1%)
Frame = -3
Query: 683 GLAWAICEHLVQVKKAPTLFATHFHELTALAQANSEVAG--NTVGVANFHVSAHIDTESR 510
GLAWAICEHL++V +APTLFATHFHELTALA N + + +GVAN+HV AHID SR
Sbjct: 759 GLAWAICEHLMEVTRAPTLFATHFHELTALAHRNDDEHQHISDIGVANYHVGAHIDPLSR 818
Query: 509 KLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFS 372
KLTMLYKVEPGACDQSFGIHVAEFANFPE+VVALA+ KAAELEDFS
Sbjct: 819 KLTMLYKVEPGACDQSFGIHVAEFANFPEAVVALAKSKAAELEDFS 864
>sp|P25847|MSH2_YEAST DNA mismatch repair protein MSH2 OS=Saccharomyces
cerevisiae GN=MSH2 PE=1 SV=2
Length = 964
Score = 109 bits (271), Expect = 2e-023
Identities = 63/143 (44%), Positives = 78/143 (54%), Gaps = 16/143 (11%)
Frame = -3
Query: 683 GLAWAICEHLVQVKKAPTLFATHFHELTALAQANSEVAGNTVGVANFHVSAHIDT----- 519
GLAWAI EH+ LFATHFHELT L++ V N HV AHI+
Sbjct: 780 GLAWAIAEHIASKIGCFALFATHFHELTELSE-------KLPNVKNMHVVAHIEKNLKEQ 832
Query: 518 --ESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPREESGKRK 345
+ +T+LYKVEPG DQSFGIHVAE FPE +V +A+ KA EL+D E K+
Sbjct: 833 KHDDEDITLLYKVEPGISDQSFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKKA 892
Query: 344 SREDDAEEVSRGTSRAHKFLKEF 276
+EV+ G R LKE+
Sbjct: 893 KL--SLQEVNEGNIRLKALLKEW 913
>sp|O74773|MSH2_SCHPO DNA mismatch repair protein msh2 OS=Schizosaccharomyces
pombe GN=msh2 PE=2 SV=2
Length = 982
Score = 94 bits (232), Expect = 7e-019
Identities = 55/123 (44%), Positives = 76/123 (61%), Gaps = 16/123 (13%)
Frame = -3
Query: 683 GLAWAICEHLVQVKKAPTLFATHFHELTALAQANSEVAGNTVGVANFHVSAHI-DTESRK 507
GLAWAI EH+V LFATH+HE+T L++ V N HV+A++ D+ES+
Sbjct: 813 GLAWAITEHIVTQIGCFCLFATHYHEMTKLSE-------EITTVKNLHVTAYVGDSESKD 865
Query: 506 LTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPREESGKRKSREDDA 327
+ +LY V GA D+SFGIHVA+ A+FP ++ +A KAAELE E+SG + D
Sbjct: 866 VALLYNVCEGASDRSFGIHVAKLAHFPPKIIEMASNKAAELE----AEDSG----AQGDT 917
Query: 326 EEV 318
+EV
Sbjct: 918 QEV 920
>sp|O13396|MSH2_NEUCR DNA mismatch repair protein msh-2 OS=Neurospora crassa
GN=msh-2 PE=3 SV=1
Length = 937
Score = 82 bits (201), Expect = 3e-015
Identities = 47/109 (43%), Positives = 69/109 (63%), Gaps = 5/109 (4%)
Frame = -3
Query: 518 ESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPR--EESGKRK 345
+ R++T+LYKVEPG CDQSFGIHVAE FP+ VV +A+ KA ELEDF+ + EE+G
Sbjct: 815 KKREVTLLYKVEPGICDQSFGIHVAELVRFPDKVVRMAKRKADELEDFTSKHEEENGGGL 874
Query: 344 SREDDAEEVSRGTSRAHKFLKEFA-EIPVDKMELKDSLKRLCEL--KDE 207
+ ++V G++ L ++ E+ +M ++ + RL EL KDE
Sbjct: 875 GVQYSKQDVEEGSALLKDVLVKWKDEVKSGRMSKEEMVARLKELVQKDE 923
>sp|Q3MHE4|MSH2_BOVIN DNA mismatch repair protein Msh2 OS=Bos taurus GN=MSH2
PE=2 SV=1
Length = 934
Score = 82 bits (200), Expect = 4e-015
Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 6/121 (4%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HV+A T LTMLY+V+ G CDQSFGIHVAE ANFP V+ A++KA ELE+F
Sbjct: 797 VNNLHVTAL--TTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIECAKQKALELEEF 854
Query: 374 ----SPREESGKRKSREDDAEEVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDE 207
P+E + + E +G +FL + ++P +M + ++L +LK E
Sbjct: 855 QNIGKPQECDEMEPAAKRCYLEREQGEKIIQEFLSKVKQVPFTEMSEESITRKLKQLKAE 914
Query: 206 L 204
+
Sbjct: 915 V 915
>sp|P43246|MSH2_HUMAN DNA mismatch repair protein Msh2 OS=Homo sapiens GN=MSH2
PE=1 SV=1
Length = 934
Score = 80 bits (197), Expect = 8e-015
Identities = 50/121 (41%), Positives = 70/121 (57%), Gaps = 6/121 (4%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HV+A T LTMLY+V+ G CDQSFGIHVAE ANFP+ V+ A++KA ELE+F
Sbjct: 797 VNNLHVTAL--TTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEF 854
Query: 374 SPREESGKRKSREDDAE----EVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDE 207
ES E A+ E +G +FL + ++P +M ++ +L +LK E
Sbjct: 855 QYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAE 914
Query: 206 L 204
+
Sbjct: 915 V 915
>sp|P43247|MSH2_MOUSE DNA mismatch repair protein Msh2 OS=Mus musculus GN=Msh2
PE=2 SV=1
Length = 935
Score = 79 bits (192), Expect = 3e-014
Identities = 50/121 (41%), Positives = 67/121 (55%), Gaps = 6/121 (4%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HV+A T LTMLY+V+ G CDQSFGIHVAE ANFP V+A A++KA ELE+F
Sbjct: 797 VNNLHVTAL--TTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIACAKQKALELEEF 854
Query: 374 SPREESGKRKSREDDAE----EVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDE 207
S E A+ E +G +FL + ++P M + +L +LK E
Sbjct: 855 QNIGTSLGCDEAEPAAKRRCLEREQGEKIILEFLSKVKQVPFTAMSEESISAKLKQLKAE 914
Query: 206 L 204
+
Sbjct: 915 V 915
>sp|Q5XXB5|MSH2_CERAE DNA mismatch repair protein Msh2 OS=Cercopithecus aethiops
GN=MSH2 PE=2 SV=1
Length = 933
Score = 78 bits (191), Expect = 4e-014
Identities = 50/121 (41%), Positives = 71/121 (58%), Gaps = 7/121 (5%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HV+A T LTMLY+V+ G CDQSFGIHVAE ANFP+ V+ A++KA ELE+F
Sbjct: 797 VNNLHVTAL--TTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEF 854
Query: 374 SPREESGKRKSREDDAE----EVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDE 207
ES + E A+ E +G +FL + ++P +M ++ +L +LK E
Sbjct: 855 QYIGES-QGYDMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAE 913
Query: 206 L 204
+
Sbjct: 914 V 914
>sp|P54275|MSH2_RAT DNA mismatch repair protein Msh2 OS=Rattus norvegicus
GN=Msh2 PE=2 SV=1
Length = 933
Score = 76 bits (186), Expect = 2e-013
Identities = 47/121 (38%), Positives = 66/121 (54%), Gaps = 6/121 (4%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HV+A T LTMLY+V+ G CDQSFGIHVAE ANFP V+ A++KA ELE+F
Sbjct: 797 VNNLHVTAL--TTEETLTMLYQVKTGVCDQSFGIHVAELANFPRHVIECAKQKALELEEF 854
Query: 374 SPREESGKRKSREDDAE----EVSRGTSRAHKFLKEFAEIPVDKMELKDSLKRLCELKDE 207
S + A+ E +G +FL + ++P + + +L +LK E
Sbjct: 855 QSIGTSQGHDETQPAAKRRCLEREQGEKIILEFLSKVKQVPFTDLSEESVSVKLKQLKAE 914
Query: 206 L 204
+
Sbjct: 915 V 915
>sp|Q553L4|MSH2_DICDI DNA mismatch repair protein Msh2 OS=Dictyostelium
discoideum GN=msh2 PE=3 SV=1
Length = 937
Score = 73 bits (177), Expect = 2e-012
Identities = 39/90 (43%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Frame = -3
Query: 554 VANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDF 375
V N HVSA T++ T+LYKVE G CDQSFGIHVA ANFP V+ A++KA ELE F
Sbjct: 835 VKNLHVSA--STQNNTFTLLYKVEQGPCDQSFGIHVAILANFPSQVIENAKQKAKELESF 892
Query: 374 SPREESGKRKSREDDAEEVSRGTSRAHKFL 285
++ +E++ ++ K L
Sbjct: 893 ESNTLKQNHNKFLEEFKEINFNSNDVEKSL 922
>sp|A7NPT5|MUTS_ROSCS DNA mismatch repair protein mutS OS=Roseiflexus
castenholzii (strain DSM 13941 / HLO8) GN=mutS PE=3 SV=1
Length = 1088
Score = 60 bits (145), Expect = 9e-009
Identities = 30/85 (35%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSP 369
N+H++A + ++ L+++ PG D+S+GIHVAE A P+ V+ A E AELE +P
Sbjct: 948 NYHMAA--TEQDGRVVFLHELRPGGADRSYGIHVAELAGIPQPVIRRATELLAELERRAP 1005
Query: 368 REESGKRKSREDDAEEVSRGTSRAH 294
R R ++ R T+R+H
Sbjct: 1006 RSTPQPAPERTEERPAAGRPTARSH 1030
>sp|A5UZK7|MUTS_ROSS1 DNA mismatch repair protein mutS OS=Roseiflexus sp.
(strain RS-1) GN=mutS PE=3 SV=1
Length = 1085
Score = 60 bits (145), Expect = 9e-009
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSP 369
N+H++A + ++ L+++ PG D+S+GIHVAE A P+SV+ A E AELE +P
Sbjct: 944 NYHMAA--TEQDGRVVFLHELRPGGADRSYGIHVAELAGIPQSVIRRASELLAELERRAP 1001
Query: 368 REESGKRKSREDDAEEVSRGTS 303
R +R DD R +S
Sbjct: 1002 RSAPPTVPARGDDRRSAGRASS 1023
>sp|C5D9H5|MUTS_GEOSW DNA mismatch repair protein mutS OS=Geobacillus sp.
(strain WCH70) GN=mutS PE=3 SV=1
Length = 860
Score = 57 bits (136), Expect = 1e-007
Identities = 33/71 (46%), Positives = 44/71 (61%), Gaps = 4/71 (5%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSP 369
N HV A E+ K+ L+K+E G DQS+GIHVAE A P S++ A+E AELE
Sbjct: 736 NVHVRA--VEENGKVVFLHKIEEGPADQSYGIHVAELAELPASLIQRAKEILAELEQQEQ 793
Query: 368 REE--SGKRKS 342
R+E SGK ++
Sbjct: 794 RKEQPSGKNEA 804
>sp|A9VS13|MUTS_BACWK DNA mismatch repair protein mutS OS=Bacillus
weihenstephanensis (strain KBAB4) GN=mutS PE=3 SV=1
Length = 890
Score = 56 bits (134), Expect = 2e-007
Identities = 28/56 (50%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A PES++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPESLIARAKEVLAQLE 790
>sp|C3P5H5|MUTS_BACAA DNA mismatch repair protein mutS OS=Bacillus anthracis
(strain A0248) GN=mutS PE=3 SV=1
Length = 892
Score = 55 bits (131), Expect = 4e-007
Identities = 27/56 (48%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A P+S++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLE 790
>sp|C3L822|MUTS_BACAC DNA mismatch repair protein mutS OS=Bacillus anthracis
(strain CDC 684 / NRRL 3495) GN=mutS PE=3 SV=1
Length = 892
Score = 55 bits (131), Expect = 4e-007
Identities = 27/56 (48%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A P+S++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLE 790
>sp|A0RHE1|MUTS_BACAH DNA mismatch repair protein mutS OS=Bacillus thuringiensis
(strain Al Hakam) GN=mutS PE=3 SV=1
Length = 890
Score = 55 bits (131), Expect = 4e-007
Identities = 27/56 (48%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A P+S++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLE 790
>sp|Q81WR3|MUTS_BACAN DNA mismatch repair protein mutS OS=Bacillus anthracis
GN=mutS PE=3 SV=1
Length = 892
Score = 55 bits (131), Expect = 4e-007
Identities = 27/56 (48%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A P+S++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLE 790
>sp|B7JJ47|MUTS_BACC0 DNA mismatch repair protein mutS OS=Bacillus cereus
(strain AH820) GN=mutS PE=3 SV=1
Length = 892
Score = 55 bits (131), Expect = 4e-007
Identities = 27/56 (48%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Frame = -3
Query: 548 NFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELE 381
N HVSA E+ K+ L+K++ GA D+S+GIHVA+ A P+S++A A+E A+LE
Sbjct: 737 NVHVSA--IEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLE 790
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 171,432,990,471
Number of Sequences: 518415
Number of Extensions: 171432990471
Number of Successful Extensions: 1050360658
Number of sequences better than 0.0: 0
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