BLASTX 7.6.2
Query= UN45609 /QuerySize=775
(774 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 OS=Hom... 129 3e-029
sp|O35547|ACSL4_RAT Long-chain-fatty-acid--CoA ligase 4 OS=Rattu... 127 7e-029
sp|Q9QUJ7|ACSL4_MOUSE Long-chain-fatty-acid--CoA ligase 4 OS=Mus... 123 1e-027
sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 3 OS=Hom... 121 7e-027
sp|Q5R668|ACSL3_PONAB Long-chain-fatty-acid--CoA ligase 3 OS=Pon... 121 7e-027
sp|Q9CZW4|ACSL3_MOUSE Long-chain-fatty-acid--CoA ligase 3 OS=Mus... 119 3e-026
sp|Q63151|ACSL3_RAT Long-chain-fatty-acid--CoA ligase 3 OS=Rattu... 119 3e-026
sp|Q55DR6|FCSA_DICDI Fatty acyl-CoA synthetase A OS=Dictyosteliu... 85 4e-016
sp|Q1ZXQ4|FCSB_DICDI Fatty acyl-CoA synthetase B OS=Dictyosteliu... 75 6e-013
sp|Q9JID6|ACSL1_CAVPO Long-chain-fatty-acid--CoA ligase 1 OS=Cav... 72 3e-012
sp|P41216|ACSL1_MOUSE Long-chain-fatty-acid--CoA ligase 1 OS=Mus... 71 8e-012
sp|P33124|ACSL6_RAT Long-chain-fatty-acid--CoA ligase 6 OS=Rattu... 70 2e-011
sp|Q91WC3|ACSL6_MOUSE Long-chain-fatty-acid--CoA ligase 6 OS=Mus... 69 2e-011
>sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens
GN=ACSL4 PE=1 SV=2
Length = 711
Score = 129 bits (322), Expect = 3e-029
Identities = 60/92 (65%), Positives = 70/92 (76%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
A+LGG +R +LSGGAPLS T RF+N+C PIGQGYGLTE+C GT +E D + GRVG
Sbjct: 430 ALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVG 489
Query: 184 APLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
APL C +KL DW EGGY I+DKP PRGEIVI
Sbjct: 490 APLICCEIKLKDWQEGGYTINDKPNPRGEIVI 521
Score = 75 bits (183), Expect = 4e-013
Identities = 37/97 (38%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
++ VV Q+ L A ++G+E T + D+C E+ + +AA ++E+FEIP K+
Sbjct: 613 ISFVVPNQKRLTLLAQQKGVEGT-WVDICNNPAMEAEILKEIREAANAMKLERFEIPIKV 671
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR +R + +D+ ++Y
Sbjct: 672 RLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMY 708
>sp|O35547|ACSL4_RAT Long-chain-fatty-acid--CoA ligase 4 OS=Rattus norvegicus
GN=Acsl4 PE=2 SV=1
Length = 670
Score = 127 bits (319), Expect = 7e-029
Identities = 59/92 (64%), Positives = 69/92 (75%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
A+LGG +R +LSGGAPLS T RF+N+C PIGQGYGLTE+C GT +E D + GRVG
Sbjct: 389 ALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVG 448
Query: 184 APLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
APL C +KL DW EGGY + DKP PRGEIVI
Sbjct: 449 APLICCEIKLKDWQEGGYTVHDKPNPRGEIVI 480
Score = 73 bits (177), Expect = 2e-012
Identities = 35/97 (36%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
++ VV Q+ L A ++G+E ++ D+C E+ + +AA ++E+FEIP K+
Sbjct: 572 ISFVVPNQKKLTLLAQQKGVE-GSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKV 630
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + +D+ ++Y
Sbjct: 631 RLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMY 667
>sp|Q9QUJ7|ACSL4_MOUSE Long-chain-fatty-acid--CoA ligase 4 OS=Mus musculus
GN=Acsl4 PE=2 SV=1
Length = 711
Score = 123 bits (308), Expect = 1e-027
Identities = 56/91 (61%), Positives = 68/91 (74%)
Frame = +1
Query: 7 VLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGA 186
++GG +R +L GGAPLS T RF+N+C+ PIGQGYGLTE+C GT +E D + GRVGA
Sbjct: 431 LVGGNVRMMLYGGAPLSPQTHRFMNVCLCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGA 490
Query: 187 PLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
PL C +KL DW EGGY + DKP PRGEIVI
Sbjct: 491 PLICCEIKLKDWQEGGYTVHDKPNPRGEIVI 521
Score = 72 bits (176), Expect = 3e-012
Identities = 35/97 (36%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
++ VV Q+ L A ++G+E ++ D+C E+ + +AA ++E+FEIP K+
Sbjct: 613 ISFVVPNQKKLTLLAQQKGVE-GSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKV 671
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + +D+ ++Y
Sbjct: 672 RLSPEPWTPETGLVTDAFKLKRKELKNHYLKDVERMY 708
>sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens
GN=ACSL3 PE=1 SV=3
Length = 720
Score = 121 bits (302), Expect = 7e-027
Identities = 57/92 (61%), Positives = 68/92 (73%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
++LGG +R LL GGAPLS TQRF+NIC P+GQGYGLTE+ GT SE D + GRVG
Sbjct: 439 SLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVG 498
Query: 184 APLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
APL C +KL +W EGGY +DKP PRGEI+I
Sbjct: 499 APLVCCEIKLKNWEEGGYFNTDKPHPRGEILI 530
Score = 77 bits (189), Expect = 9e-014
Identities = 41/97 (42%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
+ VV Q+ L A K+G++ T +E+LC + EV L +AA + +EKFEIP KI
Sbjct: 622 IGFVVPNQKELTELARKKGLKGT-WEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKI 680
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + D+ ++Y
Sbjct: 681 RLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>sp|Q5R668|ACSL3_PONAB Long-chain-fatty-acid--CoA ligase 3 OS=Pongo abelii
GN=ACSL3 PE=2 SV=2
Length = 720
Score = 121 bits (302), Expect = 7e-027
Identities = 57/92 (61%), Positives = 68/92 (73%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
++LGG +R LL GGAPLS TQRF+NIC P+GQGYGLTE+ GT SE D + GRVG
Sbjct: 439 SLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVG 498
Query: 184 APLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
APL C +KL +W EGGY +DKP PRGEI+I
Sbjct: 499 APLVCCEIKLKNWEEGGYFNTDKPHPRGEILI 530
Score = 77 bits (189), Expect = 9e-014
Identities = 41/97 (42%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
+ VV Q+ L A K+G++ T +E+LC + EV L +AA + +EKFEIP KI
Sbjct: 622 IGFVVPNQKELTELARKKGLKGT-WEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKI 680
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + D+ ++Y
Sbjct: 681 RLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>sp|Q9CZW4|ACSL3_MOUSE Long-chain-fatty-acid--CoA ligase 3 OS=Mus musculus
GN=Acsl3 PE=2 SV=1
Length = 720
Score = 119 bits (297), Expect = 3e-026
Identities = 56/91 (61%), Positives = 67/91 (73%)
Frame = +1
Query: 7 VLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGA 186
+LGG +R LL GGAPLS TQRF+NIC P+GQGYGLTE+ GT +E D + GRVGA
Sbjct: 440 LLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGA 499
Query: 187 PLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
PL C +KL +W EGGY +DKP PRGEI+I
Sbjct: 500 PLVCCEIKLKNWEEGGYFNTDKPHPRGEILI 530
Score = 75 bits (182), Expect = 6e-013
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
+ VV Q+ L A +G + T +E+LC + EV L +AA + +EKFEIP KI
Sbjct: 622 IGFVVPNQKELTELARTKGFKGT-WEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKI 680
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + D+ ++Y
Sbjct: 681 RLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>sp|Q63151|ACSL3_RAT Long-chain-fatty-acid--CoA ligase 3 OS=Rattus norvegicus
GN=Acsl3 PE=1 SV=1
Length = 720
Score = 119 bits (297), Expect = 3e-026
Identities = 56/91 (61%), Positives = 67/91 (73%)
Frame = +1
Query: 7 VLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGA 186
+LGG +R LL GGAPLS TQRF+NIC P+GQGYGLTE+ GT +E D + GRVGA
Sbjct: 440 LLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGA 499
Query: 187 PLPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
PL C +KL +W EGGY +DKP PRGEI+I
Sbjct: 500 PLVCCEIKLKNWEEGGYFNTDKPHPRGEILI 530
Score = 74 bits (181), Expect = 7e-013
Identities = 40/97 (41%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 VALVVAAQQTLEGWASKQGIEFTNFEDLCAKDQTMKEVYASLVKAAKQSRMEKFEIPAKI 461
+ VV Q+ L A +G T +E+LC + EV L +AA + +EKFEIP KI
Sbjct: 622 IGFVVPNQKELTELARTKGFNGT-WEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKI 680
Query: 462 KLLAAPWTPESGLVTAALKLKRDVIRKEFSEDLTKLY 572
+L PWTPE+GLVT A KLKR ++ + D+ ++Y
Sbjct: 681 RLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>sp|Q55DR6|FCSA_DICDI Fatty acyl-CoA synthetase A OS=Dictyostelium discoideum
GN=fcsA PE=1 SV=1
Length = 667
Score = 85 bits (209), Expect = 4e-016
Identities = 40/90 (44%), Positives = 55/90 (61%)
Frame = +1
Query: 10 LGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGAP 189
LGG+++++LSG APL F+ C P+ GYGL+E G + + +D +VG VG P
Sbjct: 382 LGGRVKFILSGSAPLDPKLAEFLRACFCCPVVSGYGLSENVGGASVAYPEDNNVGHVGPP 441
Query: 190 LPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
L +KLID PE Y +DKP PRGE+ I
Sbjct: 442 LSACEMKLIDVPEMNYFSTDKPCPRGEVCI 471
>sp|Q1ZXQ4|FCSB_DICDI Fatty acyl-CoA synthetase B OS=Dictyostelium discoideum
GN=fcsB PE=2 SV=1
Length = 673
Score = 75 bits (182), Expect = 6e-013
Identities = 38/90 (42%), Positives = 55/90 (61%), Gaps = 1/90 (1%)
Frame = +1
Query: 10 LGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGAP 189
LGG++R +LSG APLS DT+ F+ + + + QGYG +E C G DD SVG +G P
Sbjct: 399 LGGKVRVILSGSAPLSFDTEVFLRVVMCCCVLQGYGASEGCGGDACKRLDDESVGTIGPP 458
Query: 190 LPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
+ +KL+D PE GY S+ + GE+ +
Sbjct: 459 FASNEIKLVDVPELGY-DSNGEVQTGEVCL 487
>sp|Q9JID6|ACSL1_CAVPO Long-chain-fatty-acid--CoA ligase 1 OS=Cavia porcellus
GN=ACSL1 PE=2 SV=1
Length = 698
Score = 72 bits (176), Expect = 3e-012
Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 3/90 (3%)
Frame = +1
Query: 10 LGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGAP 189
LGG++R +++G AP+S F+ +G +GYG TE AG + S D + G VGAP
Sbjct: 424 LGGKVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCSLSVPGDWTAGHVGAP 483
Query: 190 LPCSFVKLIDWPEGGYLISDKPMPRGEIVI 279
+PC+F+KL+D E Y+ + M GE+ +
Sbjct: 484 MPCNFIKLVDVEEMNYMAA---MGEGEVCV 510
>sp|P41216|ACSL1_MOUSE Long-chain-fatty-acid--CoA ligase 1 OS=Mus musculus
GN=Acsl1 PE=1 SV=1
Length = 699
Score = 71 bits (172), Expect = 8e-012
Identities = 34/79 (43%), Positives = 48/79 (60%)
Frame = +1
Query: 10 LGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVGAP 189
LGG++R +++G AP+S F+ +G +GYG TE AG S D + G VGAP
Sbjct: 425 LGGKVRLMITGAAPVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAP 484
Query: 190 LPCSFVKLIDWPEGGYLIS 246
+PC++VKL+D E YL S
Sbjct: 485 MPCNYVKLVDVEEMNYLAS 503
>sp|P33124|ACSL6_RAT Long-chain-fatty-acid--CoA ligase 6 OS=Rattus norvegicus
GN=Acsl6 PE=1 SV=1
Length = 697
Score = 70 bits (169), Expect = 2e-011
Identities = 35/81 (43%), Positives = 48/81 (59%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
A LGG +R +++G AP S F+ +G + +GYG TE AG TF+ D + G VG
Sbjct: 422 ASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVG 481
Query: 184 APLPCSFVKLIDWPEGGYLIS 246
APLPC+ +KL+D E Y S
Sbjct: 482 APLPCNHIKLVDAEELNYWTS 502
>sp|Q91WC3|ACSL6_MOUSE Long-chain-fatty-acid--CoA ligase 6 OS=Mus musculus
GN=Acsl6 PE=2 SV=1
Length = 697
Score = 69 bits (168), Expect = 2e-011
Identities = 34/78 (43%), Positives = 47/78 (60%)
Frame = +1
Query: 4 AVLGGQLRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFDDTSVGRVG 183
A LGG +R +++G AP S F+ +G + +GYG TE AG TF+ D + G VG
Sbjct: 422 ASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVG 481
Query: 184 APLPCSFVKLIDWPEGGY 237
APLPC+ +KL+D E Y
Sbjct: 482 APLPCNHIKLVDAEELNY 499
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 171,432,990,471
Number of Sequences: 518415
Number of Extensions: 171432990471
Number of Successful Extensions: 1050360658
Number of sequences better than 0.0: 0
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