BLASTX 7.6.2
Query= UN45698 /QuerySize=660
(659 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subun... 189 2e-047
sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subun... 188 3e-047
sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subun... 188 3e-047
sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subun... 186 2e-046
sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subun... 181 3e-045
sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5 OS=S... 156 1e-037
sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=S... 150 1e-035
>sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subunit 12 OS=Bos
taurus GN=PSMD12 PE=2 SV=3
Length = 456
Score = 189 bits (478), Expect = 2e-047
Identities = 96/187 (51%), Positives = 133/187 (71%), Gaps = 3/187 (1%)
Frame = +3
Query: 99 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 278
G L+ I+ LL+ EKQ R A ++ T + I+++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAIVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 279 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQG 458
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE+ G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 459 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINP*SFRCR 638
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN F+
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQ-- 215
Query: 639 YKERQEK 659
+E EK
Sbjct: 216 -EENTEK 221
>sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subunit 12 OS=Homo
sapiens GN=PSMD12 PE=1 SV=3
Length = 456
Score = 188 bits (477), Expect = 3e-047
Identities = 95/187 (50%), Positives = 133/187 (71%), Gaps = 3/187 (1%)
Frame = +3
Query: 99 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 278
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 279 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQG 458
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE+ G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 459 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINP*SFRCR 638
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN F+
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQ-- 215
Query: 639 YKERQEK 659
+E EK
Sbjct: 216 -EENTEK 221
>sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo
abelii GN=PSMD12 PE=2 SV=3
Length = 456
Score = 188 bits (477), Expect = 3e-047
Identities = 95/187 (50%), Positives = 133/187 (71%), Gaps = 3/187 (1%)
Frame = +3
Query: 99 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 278
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 279 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQG 458
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE+ G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 459 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINP*SFRCR 638
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN F+
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQ-- 215
Query: 639 YKERQEK 659
+E EK
Sbjct: 216 -EENTEK 221
>sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 OS=Mus
musculus GN=Psmd12 PE=2 SV=3
Length = 456
Score = 186 bits (470), Expect = 2e-046
Identities = 90/173 (52%), Positives = 126/173 (72%)
Frame = +3
Query: 99 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 278
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W L NE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLHNENIMLLSKRRSQL 97
Query: 279 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQG 458
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE+ G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 459 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKIN 617
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKIN 210
>sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subunit 12
OS=Dictyostelium discoideum GN=psmD12 PE=2 SV=1
Length = 447
Score = 181 bits (459), Expect = 3e-045
Identities = 86/174 (49%), Positives = 132/174 (75%)
Frame = +3
Query: 96 SGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQ 275
SG L +I+ LL EKQ R AE+ T K A EI++LC+EA L+NE+++ LSK+RGQ
Sbjct: 38 SGKLIEAIENLLITEKQCRQAEDSPSTSKIAAEIIKLCYEAGRLDLVNEKLVLLSKRRGQ 97
Query: 276 LKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQ 455
L+ A++++VQ++M Y+DQ D++ ++ELI TL +S GKI+VE ERARLT+ L+KIKE++
Sbjct: 98 LRPAIKAIVQESMVYVDQITDMKQKLELIDTLRTISDGKIFVENERARLTKTLSKIKEDE 157
Query: 456 GQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKIN 617
G IA AA ++Q++ VET+G M K EKI F ++Q+R+C++ +D++RAQ++ K+N
Sbjct: 158 GDIASAAKILQDLQVETYGTMEKREKITFFIDQMRICMNNKDFIRAQLIGNKVN 211
>sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5
OS=Schizosaccharomyces pombe GN=rpn5a PE=1 SV=1
Length = 443
Score = 156 bits (394), Expect = 1e-037
Identities = 82/175 (46%), Positives = 121/175 (69%)
Frame = +3
Query: 93 NSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRG 272
N+ +++A++++LL EKQ+R A + + K I L F A D++ LNEQ+++L KK G
Sbjct: 24 NTIDIDANLEKLLIFEKQVRQASDTSTNTKVLIYIADLLFRAGDFQGLNEQLVSLFKKHG 83
Query: 273 QLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEE 452
QLKQ++ S+VQ M Y+ D++T+I LI+TL ++ GKIYVE+ERARLT+ L++IKEE
Sbjct: 84 QLKQSMTSLVQHVMTYLPGIDDLKTKINLIETLRTITDGKIYVEVERARLTQLLSQIKEE 143
Query: 453 QGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKIN 617
QG I A +++ VET+G+ EK+AFIL+QVRL L R DY A ++KIN
Sbjct: 144 QGDIKSAQEILCNEPVETYGSFDLKEKVAFILDQVRLFLLRSDYYMASTYTKKIN 198
>sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=Saccharomyces
cerevisiae GN=RPN5 PE=1 SV=3
Length = 445
Score = 150 bits (377), Expect = 1e-035
Identities = 78/176 (44%), Positives = 125/176 (71%), Gaps = 2/176 (1%)
Frame = +3
Query: 111 ASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQLKQAV 290
+++D+LL EK+ R A ++A +++ +I+ L W LNEQ+ LSKK GQLK ++
Sbjct: 34 SALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSI 93
Query: 291 QSMVQQAMQYI--DQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEEQGQI 464
Q M+Q+ M+Y+ ++ D+ TRI +I+T+ V+ KI+VE+ERAR+T+ L +IK+E+G+I
Sbjct: 94 QYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKI 153
Query: 465 AEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINP*SFR 632
EAAD++ E+ VET+G+M +EKI FILEQ+ L + + DY +A +LSRKI +F+
Sbjct: 154 DEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFK 209
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 171,432,990,471
Number of Sequences: 518415
Number of Extensions: 171432990471
Number of Successful Extensions: 1050360658
Number of sequences better than 0.0: 0
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