BLASTX 7.6.2
Query= UN45856 /QuerySize=556
(555 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Dani... 56 1e-007
sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 56 1e-007
sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo... 56 1e-007
sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus ... 56 1e-007
sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos ... 55 2e-007
sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus ... 55 3e-007
sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos ... 54 4e-007
sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo... 54 4e-007
sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus ... 54 4e-007
sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus... 54 4e-007
sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 54 5e-007
sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo... 54 5e-007
>sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Danio rerio
GN=march4 PE=2 SV=1
Length = 421
Score = 56 bits (134), Expect = 1e-007
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = -3
Query: 532 TEKDPEREREREREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFA 353
+ +D +E+ ER ++++ S R CRIC + + PC CSG+V+
Sbjct: 115 SSEDCSKEKLDER------LSLNSCTDSGVRTPLCRICFQGPEQGELLSPCRCSGSVRCT 168
Query: 352 HRDCIQRWCNEKGNTTCEICLQVYR 278
H C+ +W +E+G+ +CE+C Y+
Sbjct: 169 HEPCLIKWISERGSWSCELCYYKYQ 193
>sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xenopus laevis
GN=march3 PE=2 SV=1
Length = 252
Score = 56 bits (133), Expect = 1e-007
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+SS CRICHE + PC C+GT+ HR C++ W +
Sbjct: 46 KDGQLLSTVVRTLTTQSSFNDHPMCRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLS 105
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 106 SSNTSYCELC--HFRFSVERKPRP 127
>sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo sapiens
GN=MARCH9 PE=1 SV=2
Length = 346
Score = 56 bits (133), Expect = 1e-007
Identities = 21/66 (31%), Positives = 38/66 (57%)
Frame = -3
Query: 475 INIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCNEKGNTTCEI 296
+++ + S R +CRIC + + PC C G+V+ H+ C+ RW +E+G+ +CE+
Sbjct: 95 LSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCEL 154
Query: 295 CLQVYR 278
C Y+
Sbjct: 155 CYFKYQ 160
>sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus musculus
GN=March9 PE=2 SV=1
Length = 348
Score = 56 bits (133), Expect = 1e-007
Identities = 21/66 (31%), Positives = 38/66 (57%)
Frame = -3
Query: 475 INIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCNEKGNTTCEI 296
+++ + S R +CRIC + + PC C G+V+ H+ C+ RW +E+G+ +CE+
Sbjct: 95 LSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCEL 154
Query: 295 CLQVYR 278
C Y+
Sbjct: 155 CYFKYQ 160
>sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos taurus
GN=MARCH2 PE=2 SV=1
Length = 245
Score = 55 bits (132), Expect = 2e-007
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 5/66 (7%)
Frame = -3
Query: 430 CRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCNEKGNTTCEICLQVYRHGYTAIPKP 251
CRICHE PC CSGT+ H+ C++RW + + CE+C H A+ K
Sbjct: 64 CRICHEGANGESLLSPCGCSGTLGAVHKSCLERWLSSSNTSYCELC-----HTEFAVEKR 118
Query: 250 SKMIEE 233
S+ + E
Sbjct: 119 SRSLTE 124
>sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus musculus
GN=March4 PE=2 SV=3
Length = 409
Score = 55 bits (130), Expect = 3e-007
Identities = 23/72 (31%), Positives = 37/72 (51%)
Frame = -3
Query: 496 REMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCNEK 317
+E E ++ + S R CRIC + + PC C G+VK H+ C+ +W +E+
Sbjct: 140 KEKTEDCYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISER 199
Query: 316 GNTTCEICLQVY 281
G +CE+C Y
Sbjct: 200 GCWSCELCYYKY 211
>sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos taurus
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 54 bits (129), Expect = 4e-007
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+S CRICHE ++ PC C+GT+ HR C++ W +
Sbjct: 47 KDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLS 106
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 107 SSNTSYCELC--HFRFAVERKPRP 128
>sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo sapiens
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 54 bits (129), Expect = 4e-007
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+S CRICHE ++ PC C+GT+ HR C++ W +
Sbjct: 47 KDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLS 106
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 107 SSNTSYCELC--HFRFAVERKPRP 128
>sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus musculus
GN=March3 PE=2 SV=1
Length = 218
Score = 54 bits (129), Expect = 4e-007
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+S CRICHE ++ PC C+GT+ HR C++ W +
Sbjct: 47 KDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLS 106
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 107 SSNTSYCELC--HFRFAVERKPRP 128
>sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus norvegicus
GN=March3 PE=1 SV=1
Length = 253
Score = 54 bits (129), Expect = 4e-007
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+S CRICHE ++ PC C+GT+ HR C++ W +
Sbjct: 47 KDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLS 106
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 107 SSNTSYCELC--HFRFAVERKPRP 128
>sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xenopus tropicalis
GN=march3 PE=2 SV=1
Length = 251
Score = 54 bits (128), Expect = 5e-007
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Frame = -3
Query: 502 REREMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCN 323
++ ++ V+ T+S R CRICHE + PC C+GT+ HR C++ W +
Sbjct: 46 KDGQLLSTVVRTLTTQSFNDR-PMCRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLS 104
Query: 322 EKGNTTCEICLQVYRHGYTAIPKP 251
+ CE+C +R P+P
Sbjct: 105 SSNTSYCELC--HFRFSVERKPRP 126
>sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo sapiens
GN=MARCH4 PE=2 SV=2
Length = 410
Score = 54 bits (128), Expect = 5e-007
Identities = 23/72 (31%), Positives = 37/72 (51%)
Frame = -3
Query: 496 REMGEVVINIDETKSSKQRISRCRICHEEEAESFFEVPCACSGTVKFAHRDCIQRWCNEK 317
+E E ++ + S R CRIC + + PC C G+VK H+ C+ +W +E+
Sbjct: 141 KEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISER 200
Query: 316 GNTTCEICLQVY 281
G +CE+C Y
Sbjct: 201 GCWSCELCYYKY 212
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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