BLASTX 7.6.2
Query= UN45965 /QuerySize=916
(915 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8S528|AL2B7_ARATH Aldehyde dehydrogenase family 2 member B7,... 516 1e-145
sp|Q9SU63|AL2B4_ARATH Aldehyde dehydrogenase family 2 member B4,... 432 2e-120
sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial OS=M... 303 1e-081
sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial OS=B... 303 2e-081
sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial OS=Rat... 303 2e-081
sp|P30837|AL1B1_HUMAN Aldehyde dehydrogenase X, mitochondrial OS... 302 3e-081
sp|Q5R6B5|AL1B1_PONAB Aldehyde dehydrogenase X, mitochondrial OS... 302 3e-081
sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial OS=H... 301 5e-081
sp|Q5RF00|ALDH2_PONAB Aldehyde dehydrogenase, mitochondrial OS=P... 301 5e-081
sp|Q66HF8|AL1B1_RAT Aldehyde dehydrogenase X, mitochondrial OS=R... 299 2e-080
sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial OS=M... 299 3e-080
sp|Q9CZS1|AL1B1_MOUSE Aldehyde dehydrogenase X, mitochondrial OS... 298 4e-080
sp|Q2XQV4|ALDH2_PIG Aldehyde dehydrogenase, mitochondrial OS=Sus... 297 7e-080
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial OS=E... 294 6e-079
sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo sapiens GN... 290 1e-077
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus musculus GN... 289 3e-077
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus norvegicus... 289 3e-077
sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo sapiens GN... 285 5e-076
sp|P15437|AL1A1_HORSE Retinal dehydrogenase 1 OS=Equus caballus ... 283 2e-075
sp|Q8HYE4|AL1A1_MACFA Retinal dehydrogenase 1 OS=Macaca fascicul... 282 2e-075
>sp|Q8S528|AL2B7_ARATH Aldehyde dehydrogenase family 2 member B7, mitochondrial
OS=Arabidopsis thaliana GN=ALDH2B7 PE=2 SV=2
Length = 534
Score = 516 bits (1327), Expect = 1e-145
Identities = 255/289 (88%), Positives = 273/289 (94%), Gaps = 2/289 (0%)
Frame = +2
Query: 53 MASRRVSSLLSRSLVSSLRGKGPL--VNRGARRYSNLASALEDTITPPVKVQHTQLLLNG 226
MASRRVSSLLSRS +SS R L +NRGA+RYSNLA+A+E+TITPPVKV+HTQLL+ G
Sbjct: 1 MASRRVSSLLSRSFMSSSRSIFSLRGMNRGAQRYSNLAAAVENTITPPVKVEHTQLLIGG 60
Query: 227 KFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHGPWPRMTAYERSKI 406
+FVD+ SGKTFPTLDPR GEVIAQV+EGD EDVNRAV AARKAFD GPWP+MTAYERSKI
Sbjct: 61 RFVDAVSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMTAYERSKI 120
Query: 407 LFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIHGMTVPGD 586
LFRFADLIEKHNDEIAALETWDNGKPYEQSA+IEVPMLARVFRYYAGWADKIHGMT+PGD
Sbjct: 121 LFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIHGMTMPGD 180
Query: 587 GSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGRL 766
G HHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVG+L
Sbjct: 181 GPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGKL 240
Query: 767 LHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIVLEL 913
LHEAGLP+GVVNIVSGFG TAGAAIASHMD+DKVAFTGSTDVGKI+LEL
Sbjct: 241 LHEAGLPDGVVNIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILEL 289
>sp|Q9SU63|AL2B4_ARATH Aldehyde dehydrogenase family 2 member B4, mitochondrial
OS=Arabidopsis thaliana GN=ALDH2B4 PE=1 SV=1
Length = 538
Score = 432 bits (1110), Expect = 2e-120
Identities = 208/293 (70%), Positives = 245/293 (83%), Gaps = 6/293 (2%)
Frame = +2
Query: 53 MASRRVSSLLSRSLVSS----LRGKGPLVNRGA--RRYSNLASALEDTITPPVKVQHTQL 214
MA+RRVSSLLSRS +S R +G G RR+ ++A E+ I P V+V HTQL
Sbjct: 1 MAARRVSSLLSRSFSASSPLLFRSQGRNCYNGGILRRFGTSSAAAEEIINPSVQVSHTQL 60
Query: 215 LLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHGPWPRMTAYE 394
L+NG FVDSASGKTFPTLDPRTGEVIA VAEGD ED+NRAV AAR AFD GPWP+M+AYE
Sbjct: 61 LINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMSAYE 120
Query: 395 RSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIHGMT 574
RS++L RFADL+EKH++E+A+LETWDNGKPY+QS E+PM AR+FRYYAGWADKIHG+T
Sbjct: 121 RSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIHGLT 180
Query: 575 VPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALL 754
+P DG++ V TLHEPIGVAGQIIPWNFPLLM +WK+GPALACGNT+VLKTAEQTPL+A
Sbjct: 181 IPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAFY 240
Query: 755 VGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIVLEL 913
G+L EAGLP GV+NIVSGFG TAGAA+ASHMD+DK+AFTGSTD GK++L L
Sbjct: 241 AGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGL 293
>sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial OS=Mus musculus
GN=Aldh2 PE=1 SV=1
Length = 519
Score = 303 bits (775), Expect = 1e-081
Identities = 157/271 (57%), Positives = 192/271 (70%), Gaps = 4/271 (1%)
Frame = +2
Query: 104 LRGKGPLVNRGARRYSNLASALEDTITPP---VKVQHTQLLLNGKFVDSASGKTFPTLDP 274
LR V RG R L++A + P +V Q+ +N ++ D+ S KTFPT++P
Sbjct: 2 LRAALTTVRRGPRLSRLLSAAATSAVPAPNHQPEVFCNQIFINNEWHDAVSRKTFPTVNP 61
Query: 275 RTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEI 451
TGEVI QVAEG+ EDV++AV AAR AF G PW RM A +R ++L+R ADLIE+ +
Sbjct: 62 STGEVICQVAEGNKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYL 121
Query: 452 AALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVA 631
AALET DNGKPY S +++ M+ + RYYAGWADK HG T+P DG T HEP+GV
Sbjct: 122 AALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVC 181
Query: 632 GQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVS 811
GQIIPWNFPLLM +WKLGPALA GN VV+K AEQTPL+AL V L+ EAG P GVVNIV
Sbjct: 182 GQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVP 241
Query: 812 GFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
GFGPTAGAAIASH +DKVAFTGST+VG ++
Sbjct: 242 GFGPTAGAAIASHEGVDKVAFTGSTEVGHLI 272
>sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial OS=Bos taurus
GN=ALDH2 PE=1 SV=2
Length = 520
Score = 303 bits (774), Expect = 2e-081
Identities = 152/259 (58%), Positives = 187/259 (72%), Gaps = 1/259 (0%)
Frame = +2
Query: 131 RGARRYSNLASALEDTITPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEG 310
R RR + A+ T +V + Q+ +N ++ D+ S KTFPT++P TG+VI VAEG
Sbjct: 15 RQGRRLLSAATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAEG 74
Query: 311 DVEDVNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPY 487
D DV+RAV AAR AF G PW RM A ER ++L R ADLIE+ +AALET DNGKPY
Sbjct: 75 DKADVDRAVKAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKPY 134
Query: 488 EQSAKIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLM 667
S +++ M+ + RYYAGWADK HG T+P DG + T HEP+GV GQIIPWNFPLLM
Sbjct: 135 IISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLLM 194
Query: 668 LSWKLGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIAS 847
+WKLGPALA GN VV+K AEQTPL+AL V L+ EAG P GVVN++ GFGPTAGAAIAS
Sbjct: 195 QAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIAS 254
Query: 848 HMDIDKVAFTGSTDVGKIV 904
H D+DKVAFTGST+VG ++
Sbjct: 255 HEDVDKVAFTGSTEVGHLI 273
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial OS=Rattus norvegicus
GN=Aldh2 PE=1 SV=1
Length = 519
Score = 303 bits (774), Expect = 2e-081
Identities = 156/271 (57%), Positives = 192/271 (70%), Gaps = 4/271 (1%)
Frame = +2
Query: 104 LRGKGPLVNRGARRYSNLASALEDTITPP---VKVQHTQLLLNGKFVDSASGKTFPTLDP 274
LR RG R L++A + P +V Q+ +N ++ D+ S KTFPT++P
Sbjct: 2 LRAALSTARRGPRLSRLLSAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNP 61
Query: 275 RTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEI 451
TGEVI QVAEG+ EDV++AV AA+ AF G PW RM A +R ++L+R ADLIE+ +
Sbjct: 62 STGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYL 121
Query: 452 AALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVA 631
AALET DNGKPY S +++ M+ + RYYAGWADK HG T+P DG T HEP+GV
Sbjct: 122 AALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVC 181
Query: 632 GQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVS 811
GQIIPWNFPLLM +WKLGPALA GN VV+K AEQTPL+AL V L+ EAG P GVVNIV
Sbjct: 182 GQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVP 241
Query: 812 GFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
GFGPTAGAAIASH D+DKVAFTGST+VG ++
Sbjct: 242 GFGPTAGAAIASHEDVDKVAFTGSTEVGHLI 272
>sp|P30837|AL1B1_HUMAN Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens
GN=ALDH1B1 PE=1 SV=2
Length = 517
Score = 302 bits (772), Expect = 3e-081
Identities = 151/255 (59%), Positives = 192/255 (75%), Gaps = 3/255 (1%)
Frame = +2
Query: 143 RYSNLASALEDTITPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVED 322
RYS+ A+AL I P + + QL +N ++ D+ S KTFPT++P TGEVI VAEGD D
Sbjct: 18 RYSS-AAALPSPILNP-DIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRAD 75
Query: 323 VNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSA 499
V+RAV AAR+AF G PW RM A ER ++L ADL+E+ +A+LET DNGKP+++S
Sbjct: 76 VDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESY 135
Query: 500 KIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWK 679
+++ + +V+RY+AGWADK HG T+P DG H T HEP+GV GQIIPWNFPL+M WK
Sbjct: 136 ALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWK 195
Query: 680 LGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDI 859
L PALA GNTVV+K AEQTPLSAL + L+ EAG P GVVNI++G+GPTAGAAIA HMD+
Sbjct: 196 LAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDV 255
Query: 860 DKVAFTGSTDVGKIV 904
DKVAFTGST+VG ++
Sbjct: 256 DKVAFTGSTEVGHLI 270
>sp|Q5R6B5|AL1B1_PONAB Aldehyde dehydrogenase X, mitochondrial OS=Pongo abelii
GN=ALDH1B1 PE=2 SV=1
Length = 517
Score = 302 bits (772), Expect = 3e-081
Identities = 152/255 (59%), Positives = 192/255 (75%), Gaps = 3/255 (1%)
Frame = +2
Query: 143 RYSNLASALEDTITPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVED 322
RYS+ A+AL I P + + QL +N ++ D+ S KTFPT++P TGEVI VAEGD D
Sbjct: 18 RYSS-AAALPSPILNP-DIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRAD 75
Query: 323 VNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSA 499
V+RAV AAR+AF G PW RM A ER ++L ADL+E+ +A+LET DNGKP+++S
Sbjct: 76 VDRAVKAAREAFRLGSPWRRMDASERGRLLNCLADLVERDRVYLASLETLDNGKPFQESY 135
Query: 500 KIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWK 679
+++ + +V+RY+AGWADK HG T+P DG H T HEPIGV GQIIPWNFPL+M WK
Sbjct: 136 ALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPIGVCGQIIPWNFPLVMQGWK 195
Query: 680 LGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDI 859
L PALA GNTVV+K AEQTPLSAL + L+ EAG P GVVNI++G+GPTAGAAIA HMD+
Sbjct: 196 LAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDV 255
Query: 860 DKVAFTGSTDVGKIV 904
DKVAFTGST+VG ++
Sbjct: 256 DKVAFTGSTEVGHLI 270
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens
GN=ALDH2 PE=1 SV=2
Length = 517
Score = 301 bits (770), Expect = 5e-081
Identities = 148/233 (63%), Positives = 178/233 (76%), Gaps = 1/233 (0%)
Frame = +2
Query: 209 QLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-PWPRMT 385
Q+ +N ++ D+ S KTFPT++P TGEVI QVAEGD EDV++AV AAR AF G PW RM
Sbjct: 38 QIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMD 97
Query: 386 AYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIH 565
A R ++L R ADLIE+ +AALET DNGKPY S +++ M+ + RYYAGWADK H
Sbjct: 98 ASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH 157
Query: 566 GMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLS 745
G T+P DG T HEP+GV GQIIPWNFPLLM +WKLGPALA GN VV+K AEQTPL+
Sbjct: 158 GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 217
Query: 746 ALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
AL V L+ EAG P GVVNIV GFGPTAGAAIASH D+DKVAFTGST++G+++
Sbjct: 218 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVI 270
>sp|Q5RF00|ALDH2_PONAB Aldehyde dehydrogenase, mitochondrial OS=Pongo abelii
GN=ALDH2 PE=2 SV=1
Length = 517
Score = 301 bits (770), Expect = 5e-081
Identities = 148/233 (63%), Positives = 178/233 (76%), Gaps = 1/233 (0%)
Frame = +2
Query: 209 QLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-PWPRMT 385
Q+ +N ++ D+ S KTFPT++P TGEVI QVAEGD EDV++AV AAR AF G PW RM
Sbjct: 38 QIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMD 97
Query: 386 AYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIH 565
A R ++L R ADLIE+ +AALET DNGKPY S +++ M+ + RYYAGWADK H
Sbjct: 98 ASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH 157
Query: 566 GMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLS 745
G T+P DG T HEP+GV GQIIPWNFPLLM +WKLGPALA GN VV+K AEQTPL+
Sbjct: 158 GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 217
Query: 746 ALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
AL V L+ EAG P GVVNIV GFGPTAGAAIASH D+DKVAFTGST++G+++
Sbjct: 218 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVI 270
>sp|Q66HF8|AL1B1_RAT Aldehyde dehydrogenase X, mitochondrial OS=Rattus
norvegicus GN=Aldh1b1 PE=1 SV=1
Length = 519
Score = 299 bits (765), Expect = 2e-080
Identities = 148/250 (59%), Positives = 190/250 (76%), Gaps = 2/250 (0%)
Frame = +2
Query: 158 ASALEDTITPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAV 337
A+AL + I P ++++ QL +N ++ D+ S KTFPT++P TGEVI VAEGD DV+ AV
Sbjct: 24 AAALPNPIPNP-EIRYNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAV 82
Query: 338 VAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVP 514
AAR+AF G PW RM A ER ++L R ADL+E+ +A+LET DNGKP+++S +++
Sbjct: 83 RAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLD 142
Query: 515 MLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPAL 694
+ +V+RY AGWADK HG T+P DG H T HEP+GV GQIIPWNFPL+M WKL PAL
Sbjct: 143 EVIKVYRYLAGWADKWHGKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPAL 202
Query: 695 ACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAF 874
A GNTVV+K AEQTPLSAL + L+ EAG P GVVNI++G+GPTAGAAIA HMD+DKVAF
Sbjct: 203 ATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAF 262
Query: 875 TGSTDVGKIV 904
TGST+VG ++
Sbjct: 263 TGSTEVGHLI 272
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial OS=Mesocricetus
auratus GN=ALDH2 PE=1 SV=1
Length = 500
Score = 299 bits (763), Expect = 3e-080
Identities = 148/233 (63%), Positives = 177/233 (75%), Gaps = 1/233 (0%)
Frame = +2
Query: 209 QLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-PWPRMT 385
Q+ +N ++ D+ S KTFPT++P TGEVI QVAEG EDV++AV AAR AF G PW RM
Sbjct: 21 QIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGSKEDVDKAVKAARAAFQLGSPWRRMD 80
Query: 386 AYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGWADKIH 565
A +R ++L R ADLIE+ +AALET DNGKPY S +++ M+ + RYYAGWADK H
Sbjct: 81 ASDRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH 140
Query: 566 GMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLS 745
G T+P DG T HEP+GV GQIIPWNFPLLM +WKLGPALA GN VV+K AEQTPL+
Sbjct: 141 GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 200
Query: 746 ALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
AL V L+ EAG P GVVNIV GFGPTAGAAIASH D+DKVAFTGST+VG ++
Sbjct: 201 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLI 253
>sp|Q9CZS1|AL1B1_MOUSE Aldehyde dehydrogenase X, mitochondrial OS=Mus musculus
GN=Aldh1b1 PE=2 SV=1
Length = 519
Score = 298 bits (762), Expect = 4e-080
Identities = 147/250 (58%), Positives = 190/250 (76%), Gaps = 2/250 (0%)
Frame = +2
Query: 158 ASALEDTITPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAV 337
A+AL + I P ++ + +L +N ++ D+ S KTFPT++P TGEVI VAEGD DV+ AV
Sbjct: 24 AAALPNPIPNP-EICYNKLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAV 82
Query: 338 VAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVP 514
AAR+AF G PW RM A ER ++L R ADL+E+ +A+LET DNGKP+++S +++
Sbjct: 83 KAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLD 142
Query: 515 MLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPAL 694
+ +V+RY+AGWADK HG T+P DG H T HEP+GV GQIIPWNFPL+M WKL PAL
Sbjct: 143 EVIKVYRYFAGWADKWHGKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPAL 202
Query: 695 ACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAF 874
A GNTVV+K AEQTPLSAL + L+ EAG P GVVNI++G+GPTAGAAIA HMD+DKVAF
Sbjct: 203 ATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAF 262
Query: 875 TGSTDVGKIV 904
TGST+VG ++
Sbjct: 263 TGSTEVGHLI 272
>sp|Q2XQV4|ALDH2_PIG Aldehyde dehydrogenase, mitochondrial OS=Sus scrofa
GN=ALDH2 PE=2 SV=1
Length = 521
Score = 297 bits (760), Expect = 7e-080
Identities = 153/265 (57%), Positives = 192/265 (72%), Gaps = 6/265 (2%)
Frame = +2
Query: 122 LVNRGARRYSNLASALEDTITPP---VKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVI 292
LV R RR L++A + P ++ + Q+ +N ++ D+ S KTFPT++P TG+VI
Sbjct: 12 LVLRQGRRL--LSAAPTQAVPAPNQQPEIFYNQIFINNEWHDAISKKTFPTVNPSTGDVI 69
Query: 293 AQVAEGDVEDVNRAVVAARKAFDHG-PWPRMTAYERSKILFRFADLIEKHNDEIAALETW 469
VAEGD EDV+RAV AAR AF G PW R+ A +R ++L R ADLIE+ +AALET
Sbjct: 70 CHVAEGDKEDVDRAVEAARAAFQLGSPWRRLDASDRGRLLNRLADLIERDRTYLAALETL 129
Query: 470 DNGKPYEQSAKIEVPMLARVFRYYAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPW 649
DNGKPY S +++ M+ + RYYAGWADK HG T+P DG + T HEP+GV GQIIPW
Sbjct: 130 DNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTLPIDGDYFSYTRHEPVGVCGQIIPW 189
Query: 650 NFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTA 829
NFPLLM +WKLGPALA GN VV+K +EQTPL+AL V L+ EAG P GVVNIV G+GPTA
Sbjct: 190 NFPLLMQAWKLGPALATGNVVVMKVSEQTPLTALYVANLIKEAGFPPGVVNIVPGYGPTA 249
Query: 830 GAAIASHMDIDKVAFTGSTDVGKIV 904
GAAIASH D+DKVAFTGST+VG ++
Sbjct: 250 GAAIASHEDVDKVAFTGSTEVGHLI 274
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial OS=Equus caballus
GN=ALDH2 PE=1 SV=1
Length = 500
Score = 294 bits (752), Expect = 6e-079
Identities = 148/238 (62%), Positives = 178/238 (74%), Gaps = 1/238 (0%)
Frame = +2
Query: 194 KVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG-P 370
+V + Q+ +N ++ D+ S KTFPT++P TGEVI QVA GD EDV+RAV AAR AF G P
Sbjct: 16 EVFYNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAAGDKEDVDRAVKAARAAFQLGSP 75
Query: 371 WPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAGW 550
W RM A +R ++L R ADLIE+ +AALET DNGKPY S +++ M+ + RYYAGW
Sbjct: 76 WRRMDASDRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGW 135
Query: 551 ADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAE 730
ADK HG T+P DG T HEP+GV GQIIPWNFPLLM + KLGPALA GN VV+K AE
Sbjct: 136 ADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAAKLGPALATGNVVVMKVAE 195
Query: 731 QTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIV 904
QTPL+AL V L EAG P GVVN+V GFGPTAGAAIASH D+DKVAFTGST+VG ++
Sbjct: 196 QTPLTALYVANLTKEAGFPPGVVNVVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLI 253
>sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo sapiens GN=ALDH1A2 PE=1
SV=3
Length = 518
Score = 290 bits (741), Expect = 1e-077
Identities = 135/244 (55%), Positives = 184/244 (75%), Gaps = 1/244 (0%)
Frame = +2
Query: 182 TPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFD 361
TP +++++T++ +N ++ +S SG+ FP +P TGE + +V E D D+++AV AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89
Query: 362 HGP-WPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRY 538
G W RM A ER ++L + ADL+E+ +A +E+ + GKP+ Q+ +++ + + FRY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149
Query: 539 YAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVL 718
YAGWADKIHGMT+P DG + T HEPIGV GQIIPWNFPLLM +WK+ PAL CGNTVV+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209
Query: 719 KTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGK 898
K AEQTPLSAL +G L+ EAG P GV+NI+ G+GPTAGAAIASH+ IDK+AFTGST+VGK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 899 IVLE 910
++ E
Sbjct: 270 LIQE 273
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus musculus GN=Aldh1a2 PE=1
SV=2
Length = 518
Score = 289 bits (737), Expect = 3e-077
Identities = 136/244 (55%), Positives = 183/244 (75%), Gaps = 1/244 (0%)
Frame = +2
Query: 182 TPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFD 361
TP +++++T++ +N ++ +S SG+ FP +P TGE + +V E D D+++AV AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFS 89
Query: 362 HGP-WPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRY 538
G W RM A ER ++L + ADL+E+ +A +E+ + GKP+ Q+ I++ + + RY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRY 149
Query: 539 YAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVL 718
YAGWADKIHGMT+P DG + T HEPIGV GQIIPWNFPLLM +WK+ PAL CGNTVV+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVI 209
Query: 719 KTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGK 898
K AEQTPLSAL +G L+ EAG P GVVNI+ G+GPTAGAAIASH+ IDK+AFTGST+VGK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 899 IVLE 910
++ E
Sbjct: 270 LIQE 273
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus norvegicus GN=Aldh1a2
PE=1 SV=2
Length = 518
Score = 289 bits (737), Expect = 3e-077
Identities = 136/244 (55%), Positives = 183/244 (75%), Gaps = 1/244 (0%)
Frame = +2
Query: 182 TPPVKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFD 361
TP +++++T++ +N ++ +S SG+ FP +P TGE + +V E D D+++AV AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFS 89
Query: 362 HGP-WPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRY 538
G W RM A ER ++L + ADL+E+ +A +E+ + GKP+ Q+ I++ + + RY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRY 149
Query: 539 YAGWADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVL 718
YAGWADKIHGMT+P DG + T HEPIGV GQIIPWNFPLLM +WK+ PAL CGNTVV+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVI 209
Query: 719 KTAEQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGK 898
K AEQTPLSAL +G L+ EAG P GVVNI+ G+GPTAGAAIASH+ IDK+AFTGST+VGK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 899 IVLE 910
++ E
Sbjct: 270 LIQE 273
>sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo sapiens GN=ALDH1A1 PE=1
SV=2
Length = 501
Score = 285 bits (727), Expect = 5e-076
Identities = 140/241 (58%), Positives = 179/241 (74%), Gaps = 1/241 (0%)
Frame = +2
Query: 191 VKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG- 367
+K+Q+T++ +N ++ DS SGK FP +P T E + QV EGD EDV++AV AAR+AF G
Sbjct: 16 LKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGS 75
Query: 368 PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAG 547
PW M A ER ++L++ ADLIE+ +A +E+ + GK Y + ++ + RY AG
Sbjct: 76 PWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAG 135
Query: 548 WADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTA 727
WADKI G T+P DG+ T HEPIGV GQIIPWNFPL+ML WK+GPAL+CGNTVV+K A
Sbjct: 136 WADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPA 195
Query: 728 EQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIVL 907
EQTPL+AL V L+ EAG P GVVNIV G+GPTAGAAI+SHMDIDKVAFTGST+VGK++
Sbjct: 196 EQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIK 255
Query: 908 E 910
E
Sbjct: 256 E 256
>sp|P15437|AL1A1_HORSE Retinal dehydrogenase 1 OS=Equus caballus GN=ALDH1A1 PE=1
SV=1
Length = 500
Score = 283 bits (722), Expect = 2e-075
Identities = 136/241 (56%), Positives = 177/241 (73%), Gaps = 1/241 (0%)
Frame = +2
Query: 191 VKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG- 367
+K Q+T++ +N ++ DS SGK FP +P T E + +V EGD EDVN+AV AAR+AF G
Sbjct: 15 LKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVNKAVAAARQAFQIGS 74
Query: 368 PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAG 547
PW M A ER ++L++ ADL+E+ +A +E+ + GK + + +++ + RY AG
Sbjct: 75 PWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLMDLGGCLKTLRYCAG 134
Query: 548 WADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTA 727
WADKI G T+P DG+ T HEP+GV GQI+PWNFPLLM WK+ PAL+CGNTVV+K A
Sbjct: 135 WADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPA 194
Query: 728 EQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIVL 907
EQTPLSAL V L+ EAG P GVVNIV G+GPTAGAAI+SHMDIDKVAFTGST+VGK++
Sbjct: 195 EQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIK 254
Query: 908 E 910
E
Sbjct: 255 E 255
>sp|Q8HYE4|AL1A1_MACFA Retinal dehydrogenase 1 OS=Macaca fascicularis GN=ALDH1A1
PE=2 SV=3
Length = 501
Score = 282 bits (721), Expect = 2e-075
Identities = 139/241 (57%), Positives = 178/241 (73%), Gaps = 1/241 (0%)
Frame = +2
Query: 191 VKVQHTQLLLNGKFVDSASGKTFPTLDPRTGEVIAQVAEGDVEDVNRAVVAARKAFDHG- 367
+K+Q+T++ +N ++ DS SGK FP +P T E + QV EGD DV++AV AAR+AF G
Sbjct: 16 LKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKADVDKAVKAARQAFQIGS 75
Query: 368 PWPRMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAKIEVPMLARVFRYYAG 547
PW M A ER ++L++ ADLIE+ +A +E+ + GK Y + ++ + RY AG
Sbjct: 76 PWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAG 135
Query: 548 WADKIHGMTVPGDGSHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTA 727
WADKI G T+P DG+ T HEPIGV GQIIPWNFPL+ML WK+GPAL+CGNTVV+K A
Sbjct: 136 WADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPA 195
Query: 728 EQTPLSALLVGRLLHEAGLPEGVVNIVSGFGPTAGAAIASHMDIDKVAFTGSTDVGKIVL 907
EQTPL+AL V L+ EAG P GVVNIV G+GPTAGAAI+SHMDIDKVAFTGST+VGK++
Sbjct: 196 EQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIK 255
Query: 908 E 910
E
Sbjct: 256 E 256
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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