BLASTX 7.6.2
Query= UN46068 /QuerySize=940
(939 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabi... 244 7e-064
sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xeno... 71 1e-011
sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus ... 70 2e-011
sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo... 70 2e-011
sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens... 67 2e-010
sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=... 66 3e-010
sp|Q5SSZ7|ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus musculus... 66 4e-010
sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=... 65 8e-010
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 64 1e-009
sp|Q9ULK6|RN150_HUMAN RING finger protein 150 OS=Homo sapiens GN... 64 1e-009
sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN... 64 1e-009
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 64 1e-009
sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase RNF12-B OS=Xen... 64 1e-009
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 64 1e-009
sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase RNF12 OS=Xenop... 64 1e-009
sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase RNF12-A OS=Xen... 64 2e-009
sp|Q5DTZ6|RN150_MOUSE RING finger protein 150 OS=Mus musculus GN... 64 2e-009
sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN... 64 2e-009
sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RLIM OS=Homo s... 64 2e-009
>sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabidopsis thaliana
GN=SDIR1 PE=1 SV=1
Length = 273
Score = 244 bits (622), Expect = 7e-064
Identities = 117/136 (86%), Positives = 121/136 (88%)
Frame = +2
Query: 395 FDDLDYETLRALDSDNVPTNSMSEEEINALPVHKYKVLDPENGSSLTKQASTTSSAEKKQ 574
FDDLDYETLRALDSDNV T SMSEEEINALPVHKYKVLDPENG SL KQAST+SSAEK
Sbjct: 136 FDDLDYETLRALDSDNVSTTSMSEEEINALPVHKYKVLDPENGCSLAKQASTSSSAEKML 195
Query: 575 DSVGASKKGTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKA 754
DS SKKGTEDELTCSVCLEQVTVGE+VRTLPCLHQFHA CIDPWL QQGTCPVCKF+A
Sbjct: 196 DSANESKKGTEDELTCSVCLEQVTVGEIVRTLPCLHQFHAGCIDPWLRQQGTCPVCKFRA 255
Query: 755 HSGWQEQDDGTDDDDD 802
HSGWQEQD+ DD D
Sbjct: 256 HSGWQEQDEIDDDASD 271
Score = 141 bits (355), Expect = 7e-033
Identities = 71/79 (89%), Positives = 75/79 (94%), Gaps = 1/79 (1%)
Frame = +3
Query: 186 MSFVFRGSRGDLESGFS-GFIPERRAMRVHGARPVNSNSLAFLVTVLLLFMILNSHQMPP 362
MSFVFRGSRGDLESGFS GF+PERRAMRVHGARPVNSNSLAFLVTVLLLFMILNSHQMPP
Sbjct: 1 MSFVFRGSRGDLESGFSGGFLPERRAMRVHGARPVNSNSLAFLVTVLLLFMILNSHQMPP 60
Query: 363 NFLLWLVLGVFLMT*IMKL 419
NFLLWLVLGVFLM +++
Sbjct: 61 NFLLWLVLGVFLMATTLRM 79
>sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xenopus laevis
GN=rnf149 PE=2 SV=1
Length = 397
Score = 71 bits (172), Expect = 1e-011
Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
Frame = +2
Query: 488 VHKYKVLDPENGSSLTKQASTTSSAEKKQDSVGASKKGTE-DELTCSVCLEQVTVGEVVR 664
+ ++ + G+ ++ + + ++ + V +KG + D C+VC+E ++VR
Sbjct: 219 IQRFLYTGAQCGNQSNRKETKKAISQLQLHRVKKGEKGIDIDAENCAVCIENYKTKDLVR 278
Query: 665 TLPCLHQFHAVCIDPWLIQQGTCPVCK---FKAHSGWQEQDDGTD 790
LPC H FH +CIDPWLI+ TCP+CK KA W E ++ D
Sbjct: 279 ILPCKHIFHRLCIDPWLIEHRTCPMCKLDVIKALGFWVEPEETLD 323
>sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus musculus
GN=Rnf149 PE=2 SV=2
Length = 394
Score = 70 bits (170), Expect = 2e-011
Identities = 32/72 (44%), Positives = 44/72 (61%), Gaps = 4/72 (5%)
Frame = +2
Query: 578 SVGASKKGTE-DELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK--- 745
+V +KG + D C+VC+E V +V+R LPC H FH +CIDPWL+ TCP+CK
Sbjct: 250 TVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDV 309
Query: 746 FKAHSGWQEQDD 781
KA W + +D
Sbjct: 310 IKALGYWGDPED 321
>sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo sapiens
GN=RNF149 PE=2 SV=2
Length = 400
Score = 70 bits (169), Expect = 2e-011
Identities = 32/72 (44%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Frame = +2
Query: 578 SVGASKKGTE-DELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK--- 745
+V +KG + D C+VC+E V +++R LPC H FH +CIDPWL+ TCP+CK
Sbjct: 254 TVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDV 313
Query: 746 FKAHSGWQEQDD 781
KA W E D
Sbjct: 314 IKALGYWGEPGD 325
>sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens GN=ZNRF3 PE=2
SV=3
Length = 936
Score = 67 bits (161), Expect = 2e-010
Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 15/99 (15%)
Frame = +2
Query: 461 SEEEINALPVHKYKVLDPENGSSLTKQASTTSSAEKKQDSVGA----SKKGTEDELTCSV 628
S+ +N L V + ++ +S +K +++ S GA S T D C++
Sbjct: 247 SQNSMNRLAVQALEKMETRKFNSKSK--------GRREGSCGALDTLSSSSTSD---CAI 295
Query: 629 CLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
CLE+ GE +R +PC H+FH C+DPWL+Q TCP C+
Sbjct: 296 CLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCR 334
>sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=Rnf43 PE=2
SV=1
Length = 784
Score = 66 bits (160), Expect = 3e-010
Identities = 23/48 (47%), Positives = 33/48 (68%)
Frame = +2
Query: 620 CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHSG 763
C++CLE+ + G+ +R + CLH+FH C+DPWL Q TCP+C F G
Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHRTCPLCMFNIVEG 319
>sp|Q5SSZ7|ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus musculus GN=Znrf3 PE=2
SV=1
Length = 913
Score = 66 bits (159), Expect = 4e-010
Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 15/99 (15%)
Frame = +2
Query: 461 SEEEINALPVHKYKVLDPENGSSLTKQASTTSSAEKKQDSVGA----SKKGTEDELTCSV 628
S+ +N L V + ++ +S +K +++ S GA S T D C++
Sbjct: 244 SQNSMNRLAVQALEKMETRKFNSKSK--------GRREGSCGALDTLSSGSTSD---CAI 292
Query: 629 CLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
CLE+ GE +R +PC H+FH C+DPWL+Q TCP C+
Sbjct: 293 CLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCR 331
>sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=RNF43 PE=1
SV=1
Length = 783
Score = 65 bits (156), Expect = 8e-010
Identities = 23/48 (47%), Positives = 33/48 (68%)
Frame = +2
Query: 620 CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHSG 763
C++CLE+ + G+ +R + CLH+FH C+DPWL Q TCP+C F G
Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEG 319
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 64 bits (155), Expect = 1e-009
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 614 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHSG 763
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 226 LECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 274
>sp|Q9ULK6|RN150_HUMAN RING finger protein 150 OS=Homo sapiens GN=RNF150 PE=2
SV=2
Length = 438
Score = 64 bits (155), Expect = 1e-009
Identities = 33/78 (42%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Frame = +2
Query: 596 KGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHS--GW 766
K TE + C+VC+E +VVR LPC H FH C+DPWL+ TCP+CK G
Sbjct: 269 KETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGI 328
Query: 767 QEQDDGTDDDDDDDEASV 820
D DD D E S+
Sbjct: 329 PPNADCMDDLPTDFEGSL 346
>sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN=Rnf215 PE=2
SV=1
Length = 379
Score = 64 bits (155), Expect = 1e-009
Identities = 27/50 (54%), Positives = 35/50 (70%), Gaps = 3/50 (6%)
Frame = +2
Query: 599 GTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKF 748
GTE TC+VCL+ + +R LPC H+FH C+DPWL+ Q TCP+CKF
Sbjct: 323 GTE---TCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKF 369
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 64 bits (154), Expect = 1e-009
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 614 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHSG 763
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 226 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 274
>sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase RNF12-B OS=Xenopus laevis
GN=rnf12-b PE=2 SV=1
Length = 757
Score = 64 bits (154), Expect = 1e-009
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +2
Query: 575 DSVGASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
D++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 687 DNLSTRNYGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 744
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 64 bits (154), Expect = 1e-009
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 614 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHSG 763
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 225 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 273
>sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase RNF12 OS=Xenopus tropicalis
GN=rnf12 PE=2 SV=1
Length = 639
Score = 64 bits (154), Expect = 1e-009
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +2
Query: 575 DSVGASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
D++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 569 DNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 626
>sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase RNF12-A OS=Xenopus laevis
GN=rnf12-a PE=1 SV=1
Length = 622
Score = 64 bits (153), Expect = 2e-009
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +2
Query: 575 DSVGASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
D++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 552 DNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 609
>sp|Q5DTZ6|RN150_MOUSE RING finger protein 150 OS=Mus musculus GN=Rnf150 PE=2
SV=2
Length = 437
Score = 64 bits (153), Expect = 2e-009
Identities = 33/78 (42%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Frame = +2
Query: 596 KGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKFKAHS--GW 766
K TE + C+VC+E +VVR LPC H FH C+DPWL+ TCP+CK G
Sbjct: 268 KETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGI 327
Query: 767 QEQDDGTDDDDDDDEASV 820
D DD D E S+
Sbjct: 328 PPNADCMDDLPIDFEGSL 345
>sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN=RNF215 PE=1
SV=2
Length = 377
Score = 64 bits (153), Expect = 2e-009
Identities = 24/44 (54%), Positives = 32/44 (72%)
Frame = +2
Query: 617 TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCKF 748
TC+VCL+ + +R LPC H+FH C+DPWL+ Q TCP+CKF
Sbjct: 324 TCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKF 367
>sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RLIM OS=Homo sapiens GN=RLIM
PE=1 SV=3
Length = 624
Score = 64 bits (153), Expect = 2e-009
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +2
Query: 575 DSVGASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLIQQGTCPVCK 745
D++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 554 DNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 611
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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