BLASTX 7.6.2
Query= UN46284 /QuerySize=1006
(1005 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q55BI3|OTU1_DICDI Ubiquitin thioesterase OTU1 OS=Dictyosteliu... 158 1e-037
sp|Q567B1|OTU1_DANRE Ubiquitin thioesterase OTU1 OS=Danio rerio ... 136 2e-031
sp|Q9VRJ9|OTU1_DROME Ubiquitin thioesterase OTU1 OS=Drosophila m... 136 4e-031
sp|Q29FC9|OTU1_DROPS Ubiquitin thioesterase OTU1 OS=Drosophila p... 136 4e-031
sp|Q0IH43|OTU1_XENLA Ubiquitin thioesterase OTU1 OS=Xenopus laev... 135 5e-031
sp|Q5F3A6|OTU1_CHICK Ubiquitin thioesterase OTU1 OS=Gallus gallu... 134 9e-031
sp|Q5VVQ6|OTU1_HUMAN Ubiquitin thioesterase OTU1 OS=Homo sapiens... 133 2e-030
sp|Q32Q05|OTU1_RAT Ubiquitin thioesterase OTU1 OS=Rattus norvegi... 133 2e-030
sp|Q05B57|OTU1_BOVIN Ubiquitin thioesterase OTU1 OS=Bos taurus G... 133 3e-030
sp|Q8CB27|OTU1_MOUSE Ubiquitin thioesterase OTU1 OS=Mus musculus... 131 1e-029
sp|O13974|OTU1_SCHPO Putative ubiquitin thioesterase otu1 OS=Sch... 101 8e-021
sp|P43558|OTU1_YEAST Ubiquitin thioesterase OTU1 OS=Saccharomyce... 92 4e-018
>sp|Q55BI3|OTU1_DICDI Ubiquitin thioesterase OTU1 OS=Dictyostelium discoideum
GN=yod1 PE=3 SV=1
Length = 325
Score = 158 bits (397), Expect = 1e-037
Identities = 81/160 (50%), Positives = 104/160 (65%), Gaps = 1/160 (0%)
Frame = +3
Query: 168 GIIVRRVISSDNSCLFNAIGYVM-DKDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNEE 344
G RRV DNSCLF+A+ YV+ DK++ K LR +IA V SD +YNEA LGK NE
Sbjct: 121 GYATRRVTDDDNSCLFSAVAYVLEDKNRLKGYSLRALIAQNVKSDPFEYNEAVLGKSNEG 180
Query: 345 YCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLHY 524
YC WI NP WGGAIELSIL+++Y EIAA+DI T YG+ + Y+ERV LIYDG+HY
Sbjct: 181 YCNWIQNPKNWGGAIELSILSNHYKVEIAAFDISTQLMYCYGEDRKYTERVYLIYDGIHY 240
Query: 525 DALALSPFEDAEEDFDMAIFPVGKDRSIGAIERACSKSSK 644
DAL++ ++ EDFD+ F V S+ ++ K K
Sbjct: 241 DALSICLTKNGPEDFDITRFSVDDKDSLAKMKVLIEKEFK 280
>sp|Q567B1|OTU1_DANRE Ubiquitin thioesterase OTU1 OS=Danio rerio GN=yod1 PE=2
SV=1
Length = 301
Score = 136 bits (342), Expect = 2e-031
Identities = 66/124 (53%), Positives = 85/124 (68%), Gaps = 3/124 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ RRV+ +DNSCLF ++ YVM+ D A E+R +IA VASD Y+EA LGK NE
Sbjct: 101 VVERRVVPADNSCLFTSVNYVMEGGVYDPACASEMRGLIAQIVASDPTAYSEAVLGKTNE 160
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYC WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 161 EYCTWIRRDDTWGGAIEVSILSKFYQCEICVVDTQTVRVDRFGEDAGYTKRVLLIYDGIH 220
Query: 522 YDAL 533
YD L
Sbjct: 221 YDPL 224
Score = 65 bits (158), Expect = 5e-010
Identities = 31/61 (50%), Positives = 40/61 (65%), Gaps = 2/61 (3%)
Frame = +1
Query: 598 IDPLVL*KGLVLNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQ 777
+D ++L L L + +RKR +TD F LRC VCQ G++GQKEA EHA+ TGH NF
Sbjct: 242 VDDVIL--AQALELADEARRKRQFTDVNRFALRCMVCQTGLVGQKEAREHAKETGHTNFG 299
Query: 778 E 780
E
Sbjct: 300 E 300
>sp|Q9VRJ9|OTU1_DROME Ubiquitin thioesterase OTU1 OS=Drosophila melanogaster
GN=CG4603 PE=1 SV=1
Length = 347
Score = 136 bits (340), Expect = 4e-031
Identities = 66/143 (46%), Positives = 96/143 (67%), Gaps = 5/143 (3%)
Frame = +3
Query: 168 GIIVRRVISSDNSCLFNAIGYVMD--KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
GI++++V+ +DNSCLF +I +V++ D + + +R +IA VA+D + YN+A LGK N
Sbjct: 148 GILLKKVVPADNSCLFTSIRFVLNGKVDNEGSEMMRHIIAQEVAADPQSYNDAVLGKSNA 207
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYCAWI D WGGAIE+SIL++YYG EI DIQ + + +G+ KN+ RV L++DG+H
Sbjct: 208 EYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGEDKNFGLRVFLLFDGIH 267
Query: 522 YDALALSPFEDAEEDFDMAIFPV 590
YD L + E + IFPV
Sbjct: 268 YDPLYM---ETSPSAAPATIFPV 287
Score = 53 bits (125), Expect = 3e-006
Identities = 23/48 (47%), Positives = 30/48 (62%)
Frame = +1
Query: 637 LVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L + Q R YT+ FTLRC C + ++GQ +A EHA+ TGH NF E
Sbjct: 299 LANEAQSSRQYTNVDKFTLRCMQCDVRLVGQVQAQEHAKQTGHKNFGE 346
>sp|Q29FC9|OTU1_DROPS Ubiquitin thioesterase OTU1 OS=Drosophila pseudoobscura
pseudoobscura GN=GA18292 PE=3 SV=1
Length = 358
Score = 136 bits (340), Expect = 4e-031
Identities = 64/143 (44%), Positives = 97/143 (67%), Gaps = 5/143 (3%)
Frame = +3
Query: 168 GIIVRRVISSDNSCLFNAIGYVMD--KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
GI++++V+ +DNSCLF +I +V++ D + + +R +IA V++D ++YN+A LGK N
Sbjct: 159 GILLKKVVPADNSCLFTSIRFVLNGKVDNEGSEMMRHIIAQEVSADTQQYNDAVLGKSNS 218
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
+YCAWI D WGGAIE+SIL++YYG EI DIQ + + +G+ KN+ RV L++DG+H
Sbjct: 219 DYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGEDKNFGLRVFLLFDGIH 278
Query: 522 YDALALSPFEDAEEDFDMAIFPV 590
YD L + E + IFPV
Sbjct: 279 YDPLYM---ETQQNSVPATIFPV 298
>sp|Q0IH43|OTU1_XENLA Ubiquitin thioesterase OTU1 OS=Xenopus laevis GN=yod1 PE=2
SV=1
Length = 304
Score = 135 bits (339), Expect = 5e-031
Identities = 67/123 (54%), Positives = 86/123 (69%), Gaps = 3/123 (2%)
Frame = +3
Query: 174 IVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNEE 344
IVRRV+ +DNSCLF +I YV++ D A E+R +IA VASD+ Y +A LGK NEE
Sbjct: 105 IVRRVVPADNSCLFTSIYYVVEGGVYDPACALEMRSLIAEIVASDQSAYCDAVLGKSNEE 164
Query: 345 YCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLHY 524
YC+WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+HY
Sbjct: 165 YCSWIRREDTWGGAIEVSILSKFYQCEICVVDTQTVRIDRFGEDSGYTKRVLLIYDGIHY 224
Query: 525 DAL 533
D L
Sbjct: 225 DPL 227
>sp|Q5F3A6|OTU1_CHICK Ubiquitin thioesterase OTU1 OS=Gallus gallus GN=YOD1 PE=2
SV=1
Length = 302
Score = 134 bits (337), Expect = 9e-031
Identities = 65/124 (52%), Positives = 85/124 (68%), Gaps = 3/124 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ RRV+ +DNSCLF ++ YV++ D APE+R +IA VASD E Y EA LGK N
Sbjct: 102 VLARRVVPADNSCLFTSVYYVVEGGVYDPGCAPEMRSLIAQIVASDPEAYCEAVLGKTNR 161
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYC WI + WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 162 EYCEWIRREETWGGAIEVSILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIH 221
Query: 522 YDAL 533
YD L
Sbjct: 222 YDPL 225
Score = 62 bits (149), Expect = 6e-009
Identities = 29/50 (58%), Positives = 34/50 (68%)
Frame = +1
Query: 631 LNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L L + +RKR +TD FTLRC VCQ G+ GQ EA EHA+ TGH NF E
Sbjct: 252 LELADEARRKRQFTDVNRFTLRCMVCQKGLTGQVEAREHAKETGHTNFGE 301
>sp|Q5VVQ6|OTU1_HUMAN Ubiquitin thioesterase OTU1 OS=Homo sapiens GN=YOD1 PE=1
SV=1
Length = 348
Score = 133 bits (334), Expect = 2e-030
Identities = 63/124 (50%), Positives = 87/124 (70%), Gaps = 3/124 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ R V+ +DNSCLF ++ YV++ + APE+R++IA VASD + Y+EA LGK N+
Sbjct: 148 VLTRTVVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQ 207
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYC WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 208 EYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIH 267
Query: 522 YDAL 533
YD L
Sbjct: 268 YDPL 271
Score = 61 bits (147), Expect = 1e-008
Identities = 28/50 (56%), Positives = 34/50 (68%)
Frame = +1
Query: 631 LNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L L + +R+R +TD FTLRC VCQ G+ GQ EA EHA+ TGH NF E
Sbjct: 298 LELADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGE 347
>sp|Q32Q05|OTU1_RAT Ubiquitin thioesterase OTU1 OS=Rattus norvegicus GN=Yod1
PE=2 SV=1
Length = 343
Score = 133 bits (334), Expect = 2e-030
Identities = 63/124 (50%), Positives = 86/124 (69%), Gaps = 3/124 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ R + +DNSCLF ++ YV++ + APE+R++IA VASD + Y+EA LGK NE
Sbjct: 143 VLTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDLYSEAILGKTNE 202
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYC WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 203 EYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIH 262
Query: 522 YDAL 533
YD L
Sbjct: 263 YDPL 266
Score = 60 bits (144), Expect = 2e-008
Identities = 27/50 (54%), Positives = 34/50 (68%)
Frame = +1
Query: 631 LNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L L + +RKR +TD FTLRC +CQ G+ GQ EA +HA+ TGH NF E
Sbjct: 293 LELADEARRKRQFTDVNRFTLRCMLCQKGLTGQAEARDHARETGHTNFGE 342
>sp|Q05B57|OTU1_BOVIN Ubiquitin thioesterase OTU1 OS=Bos taurus GN=YOD1 PE=2
SV=1
Length = 348
Score = 133 bits (333), Expect = 3e-030
Identities = 64/126 (50%), Positives = 86/126 (68%), Gaps = 3/126 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ R + +DNSCLF ++ YV++ + APE+R+ IA VASD + Y+EA LGK NE
Sbjct: 148 VLARMAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRFIAQIVASDPDFYSEAILGKTNE 207
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
EYC WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 208 EYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIH 267
Query: 522 YDALAL 539
YD L L
Sbjct: 268 YDPLHL 273
Score = 60 bits (144), Expect = 2e-008
Identities = 27/50 (54%), Positives = 34/50 (68%)
Frame = +1
Query: 631 LNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L L + ++KR +TD FTLRC VCQ G+ GQ EA +HA+ TGH NF E
Sbjct: 298 LELADEARKKRQFTDVNRFTLRCMVCQKGLTGQAEARDHAKETGHTNFGE 347
>sp|Q8CB27|OTU1_MOUSE Ubiquitin thioesterase OTU1 OS=Mus musculus GN=Yod1 PE=2
SV=1
Length = 343
Score = 131 bits (327), Expect = 1e-029
Identities = 62/124 (50%), Positives = 85/124 (68%), Gaps = 3/124 (2%)
Frame = +3
Query: 171 IIVRRVISSDNSCLFNAIGYVMD---KDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNE 341
++ R + +DNSCLF ++ YV++ + APE+R++IA VASD Y+EA LGK NE
Sbjct: 143 VLTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPVLYSEAILGKTNE 202
Query: 342 EYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLH 521
+YC WI D WGGAIE+SIL+ +Y EI D QT R D +G+ Y++RV+LIYDG+H
Sbjct: 203 DYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIH 262
Query: 522 YDAL 533
YD L
Sbjct: 263 YDPL 266
Score = 61 bits (146), Expect = 1e-008
Identities = 27/50 (54%), Positives = 34/50 (68%)
Frame = +1
Query: 631 LNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQE 780
L L + +RKR +TD FTLRC +CQ G+ GQ EA +HA+ TGH NF E
Sbjct: 293 LELADEARRKRQFTDVNRFTLRCMICQKGLTGQAEARDHARETGHTNFGE 342
>sp|O13974|OTU1_SCHPO Putative ubiquitin thioesterase otu1
OS=Schizosaccharomyces pombe GN=otu1 PE=1 SV=1
Length = 329
Score = 101 bits (251), Expect = 8e-021
Identities = 56/140 (40%), Positives = 81/140 (57%), Gaps = 6/140 (4%)
Frame = +3
Query: 168 GIIVRRVISSDNSCLFNAIGYVMDKDKKKAP-ELRQVIAAAVASDKEKYNEAFLGKQNEE 344
G I RV+ DNSCLF A + K +P ELR+++A V S+ + Y+ A LGK + E
Sbjct: 133 GDIALRVMPDDNSCLFRA----LSKPLGFSPYELREIVANQVLSNPDIYSTAILGKPSIE 188
Query: 345 YCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLHY 524
Y +WI WGG IELSIL+ ++G EI + D++T R D Y +R ++Y G+HY
Sbjct: 189 YASWIRKETSWGGYIELSILSSHFGVEICSVDVKTGRVDSYNPQPATGQRTYIVYSGIHY 248
Query: 525 DALALSPFEDAEEDFDMAIF 584
D AL+ + D D+ +F
Sbjct: 249 DLAALAAVL-WDTDVDVVLF 267
Score = 57 bits (135), Expect = 2e-007
Identities = 22/39 (56%), Positives = 30/39 (76%)
Frame = +1
Query: 667 YTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQEY 783
YTDTA+F++RC +C G++G+K+A HA ATGH F EY
Sbjct: 291 YTDTASFSIRCTICGTGLVGEKDATAHALATGHTQFGEY 329
>sp|P43558|OTU1_YEAST Ubiquitin thioesterase OTU1 OS=Saccharomyces cerevisiae
GN=OTU1 PE=1 SV=1
Length = 301
Score = 92 bits (228), Expect = 4e-018
Identities = 42/129 (32%), Positives = 79/129 (61%), Gaps = 2/129 (1%)
Frame = +3
Query: 165 EGIIVRRVISSDNSCLFNAIGYVMDKDKKKAPELRQVIAAAVASDKEKYNEAFLGKQNEE 344
E ++ + DNSCLF+AI Y + K + +LR++++ V ++ K+N+A L K N++
Sbjct: 106 ENVLSVHPVLDDNSCLFHAIAYGIFK-QDSVRDLREMVSKEVLNNPVKFNDAILDKPNKD 164
Query: 345 YCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTKNYSERVMLIYDGLHY 524
Y WIL + WGGAIE+ I++D I DI + + + + K + ++++++G+HY
Sbjct: 165 YAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDK-FDNYILILFNGIHY 223
Query: 525 DALALSPFE 551
D+L ++ F+
Sbjct: 224 DSLTMNEFK 232
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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