BLASTX 7.6.2
Query= UN46285 /QuerySize=939
(938 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q1LUI2|HDDC2_DANRE HD domain-containing protein 2 OS=Danio re... 176 2e-043
sp|Q0P565|HDDC2_BOVIN HD domain-containing protein 2 OS=Bos taur... 164 7e-040
sp|Q7Z4H3|HDDC2_HUMAN HD domain-containing protein 2 OS=Homo sap... 164 7e-040
sp|Q3SXD3|HDDC2_MOUSE HD domain-containing protein 2 OS=Mus musc... 164 1e-039
sp|Q66L17|HDDC2_XENLA HD domain-containing protein 2 OS=Xenopus ... 163 2e-039
sp|P87242|YC0H_SCHPO HD domain-containing protein C4G3.17 OS=Sch... 162 5e-039
sp|Q54FK1|HDDC2_DICDI HD domain-containing protein 2 homolog OS=... 151 8e-036
sp|P38331|YB92_YEAST HD domain-containing protein YBR242W OS=Sac... 139 3e-032
sp|P53144|YGK1_YEAST HD domain-containing protein YGL101W OS=Sac... 135 6e-031
>sp|Q1LUI2|HDDC2_DANRE HD domain-containing protein 2 OS=Danio rerio GN=hddc2
PE=2 SV=1
Length = 200
Score = 176 bits (445), Expect = 2e-043
Identities = 88/160 (55%), Positives = 118/160 (73%), Gaps = 4/160 (2%)
Frame = +1
Query: 265 IDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCIKMAIV 444
+ F+ L +LK PR GW R++K PES++DHMYRM +MAL DI+ VN+++C+K+A+V
Sbjct: 5 LQFMKLVGQLKRVPRTGWVYRNIKQPESVSDHMYRMSMMALTIQDIS-VNKERCMKLALV 63
Query: 445 HDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELWREYEANASPE 624
HD+AE IVGDI P+ VSK EK+RRE +A+ H+ LL G R +EI LW EYE +SPE
Sbjct: 64 HDLAECIVGDIAPADNVSKAEKHRREKDAMVHITGLLDDGLR-KEIYNLWEEYETQSSPE 122
Query: 625 AKVVKDFDKLELILQALEYEQEQGKD--LEEFFESTAGKF 738
AK+VK+ D LE+I+QA EYE+ +GK L+EFF ST GKF
Sbjct: 123 AKLVKELDNLEMIIQAHEYEELEGKPGRLQEFFVSTEGKF 162
>sp|Q0P565|HDDC2_BOVIN HD domain-containing protein 2 OS=Bos taurus GN=HDDC2
PE=2 SV=1
Length = 205
Score = 164 bits (415), Expect = 7e-040
Identities = 82/164 (50%), Positives = 117/164 (71%), Gaps = 4/164 (2%)
Frame = +1
Query: 253 ASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCIK 432
A + + FL L +LK PR GW R+V+ PES++DHMYRM +MAL+ D +N+D+C++
Sbjct: 15 ARNLLQFLRLVGQLKRVPRTGWVYRNVQKPESVSDHMYRMAVMALVTKD-EHLNKDRCVR 73
Query: 433 MAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELWREYEAN 612
+A+VHD+AE IVGDI P+ V +EEK+RRE EA++ + +LL + +E+ ELW EYE
Sbjct: 74 LALVHDMAECIVGDIAPADNVPREEKHRREEEAMKQLTQLL-PEDLQKELYELWEEYETQ 132
Query: 613 ASPEAKVVKDFDKLELILQALEYEQEQGKD--LEEFFESTAGKF 738
+S EAK VK D+ E+ILQA EYE + K L++F++STAGKF
Sbjct: 133 SSAEAKFVKQLDQCEMILQASEYEDLENKPGRLQDFYDSTAGKF 176
>sp|Q7Z4H3|HDDC2_HUMAN HD domain-containing protein 2 OS=Homo sapiens GN=HDDC2
PE=1 SV=1
Length = 204
Score = 164 bits (415), Expect = 7e-040
Identities = 83/164 (50%), Positives = 117/164 (71%), Gaps = 4/164 (2%)
Frame = +1
Query: 253 ASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCIK 432
A S + FL L +LK PR GW R+V+ PES++DHMYRM +MA++ D +N+D+C++
Sbjct: 14 ARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKD-DRLNKDRCVR 72
Query: 433 MAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELWREYEAN 612
+A+VHD+AE IVGDI P+ + KEEK+RRE EA++ + +LL R +E+ ELW EYE
Sbjct: 73 LALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLR-KELYELWEEYETQ 131
Query: 613 ASPEAKVVKDFDKLELILQALEYEQEQGKD--LEEFFESTAGKF 738
+S EAK VK D+ E+ILQA EYE + K L++F++STAGKF
Sbjct: 132 SSAEAKFVKQLDQCEMILQASEYEDLEHKPGRLQDFYDSTAGKF 175
>sp|Q3SXD3|HDDC2_MOUSE HD domain-containing protein 2 OS=Mus musculus GN=Hddc2
PE=2 SV=1
Length = 199
Score = 164 bits (414), Expect = 1e-039
Identities = 83/165 (50%), Positives = 117/165 (70%), Gaps = 4/165 (2%)
Frame = +1
Query: 250 SASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCI 429
S + + FL L +LK PR GW R+V+ PES++DHMYRM +MA++ D +N+D+CI
Sbjct: 8 SGAGLLRFLRLVGQLKRVPRTGWVYRNVEKPESVSDHMYRMAVMAMVTRD-DRLNKDRCI 66
Query: 430 KMAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELWREYEA 609
++A+VHD+AE IVGDI P+ + KEEK+RRE EA++ + +LL R +E+ ELW EYE
Sbjct: 67 RLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLR-KELYELWEEYET 125
Query: 610 NASPEAKVVKDFDKLELILQALEYEQEQGKD--LEEFFESTAGKF 738
+S EAK VK D+ E+ILQA EYE + K L++F++STAGKF
Sbjct: 126 QSSEEAKFVKQLDQCEMILQASEYEDLENKPGRLQDFYDSTAGKF 170
>sp|Q66L17|HDDC2_XENLA HD domain-containing protein 2 OS=Xenopus laevis GN=hddc2
PE=2 SV=1
Length = 201
Score = 163 bits (412), Expect = 2e-039
Identities = 79/166 (47%), Positives = 118/166 (71%), Gaps = 4/166 (2%)
Frame = +1
Query: 250 SASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCI 429
+ S + F+ L +LK PR GW R V+ PES++DHMYRM +MA++ D +N+D+CI
Sbjct: 10 AGKSLLQFMKLVGQLKRVPRTGWIYRQVEKPESVSDHMYRMAVMAMLTED-RKLNKDRCI 68
Query: 430 KMAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELWREYEA 609
++A+VHD+AE IVGDI P+ ++KEEK+R+E A+EH+ +LL + E+ +LW EYE
Sbjct: 69 RLALVHDMAECIVGDIAPADNIAKEEKHRKEKAAMEHLTQLLPDNLKT-EVYDLWEEYEH 127
Query: 610 NASPEAKVVKDFDKLELILQALEYEQEQGKD--LEEFFESTAGKFQ 741
+ EAK VK+ D+ E+ILQALEYE+ + + L++F+ STAGKF+
Sbjct: 128 QFTAEAKFVKELDQCEMILQALEYEELEKRPGRLQDFYNSTAGKFK 173
>sp|P87242|YC0H_SCHPO HD domain-containing protein C4G3.17
OS=Schizosaccharomyces pombe GN=SPCC4G3.17 PE=2 SV=1
Length = 198
Score = 162 bits (408), Expect = 5e-039
Identities = 89/184 (48%), Positives = 124/184 (67%), Gaps = 9/184 (4%)
Frame = +1
Query: 259 SAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKCIKMA 438
S + FL SRLKTTPR GW ++ PESIADHMYRMG++ ++ +D +N+++C+K+A
Sbjct: 8 SIVPFLDCLSRLKTTPRTGWLYHGIEKPESIADHMYRMGILTMLCND-PSINKERCLKIA 66
Query: 439 IVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKL---LGGGERAEEIAELWREYEA 609
+VHD+AE+IVGDITP VSKEEK+R ESEA+ + + L +AEEI EL+ EYE+
Sbjct: 67 VVHDMAESIVGDITPHENVSKEEKHRMESEAMVSITQQLIPLNLSLQAEEIKELFLEYES 126
Query: 610 NASPEAKVVKDFDKLELILQALEYEQEQG--KDLEEFFESTAGK-FQTDIGKAWALEIAS 780
++PEAK VKD DK E+I Q EYE++ KDL +F + AGK Q + K W ++
Sbjct: 127 ASTPEAKFVKDIDKFEMIAQMFEYERKFNGEKDLSQF--TWAGKLIQHPLVKGWLNDVLQ 184
Query: 781 RRRK 792
R +
Sbjct: 185 EREQ 188
>sp|Q54FK1|HDDC2_DICDI HD domain-containing protein 2 homolog OS=Dictyostelium
discoideum GN=hddc2 PE=3 SV=1
Length = 190
Score = 151 bits (380), Expect = 8e-036
Identities = 83/190 (43%), Positives = 118/190 (62%), Gaps = 13/190 (6%)
Frame = +1
Query: 256 SSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMA-------LIASDIAGVN 414
S+ ++F +C +LKT R GW V+ PES++DHMYRM +M LI D ++
Sbjct: 2 SNYLEFFKICGKLKTLKRTGWVNHGVELPESVSDHMYRMAMMGMCLDKKELIGEDGKEID 61
Query: 415 RDKCIKMAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLLGGGERAEEIAELW 594
+ K IKMA+VHD+ E++VGD TP ++KEEK + E A+ + L GE +EI +LW
Sbjct: 62 KMKIIKMALVHDLGESLVGDFTPHDKITKEEKYQLEKNAIIEITNTL-SGEVGKEIFDLW 120
Query: 595 REYEANASPEAKVVKDFDKLELILQALEYEQ-----EQGKDLEEFFESTAGKFQTDIGKA 759
+EYE + EA +VKDFDK E+ILQA EYE+ E L+ FF+ST GKF + K+
Sbjct: 121 QEYEDCKTNEALLVKDFDKFEMILQAYEYEKQPHQLENKIKLQSFFDSTRGKFHHPLFKS 180
Query: 760 WALEIASRRR 789
AL++ S R+
Sbjct: 181 LALQLESDRK 190
>sp|P38331|YB92_YEAST HD domain-containing protein YBR242W OS=Saccharomyces
cerevisiae GN=YBR242W PE=1 SV=1
Length = 238
Score = 139 bits (350), Expect = 3e-032
Identities = 76/187 (40%), Positives = 118/187 (63%), Gaps = 7/187 (3%)
Frame = +1
Query: 247 PSASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKC 426
P + + FL++ +LK R G+ +K ESI+DHMYR+ ++ ++ D + VNRDKC
Sbjct: 43 PHPNYILAFLNVVQQLKIQRRTGYLDLGIKECESISDHMYRLSIITMLIKD-SRVNRDKC 101
Query: 427 IKMAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLL---GGGERAEEIAELWR 597
+++A+VHDIAE++VGDITP + KEEK+RRE E ++++C L A+EI + W
Sbjct: 102 VRIALVHDIAESLVGDITPVDPIGKEEKHRREWETIKYLCNALIKPYNEIAAKEIMDDWL 161
Query: 598 EYEANASPEAKVVKDFDKLELILQALEYEQEQ--GKDLEEFFESTAGKFQTDIGKAWALE 771
YE S EA+ VKD DK E+++Q EYE+E K+ ++FF + A +TD K W +
Sbjct: 162 AYENVTSLEARYVKDIDKYEMLVQCFEYEREYKGTKNFDDFFGAVA-SIKTDEVKGWTSD 220
Query: 772 IASRRRK 792
+ +R+K
Sbjct: 221 LVVQRQK 227
>sp|P53144|YGK1_YEAST HD domain-containing protein YGL101W OS=Saccharomyces
cerevisiae GN=YGL101W PE=1 SV=1
Length = 215
Score = 135 bits (338), Expect = 6e-031
Identities = 73/186 (39%), Positives = 111/186 (59%), Gaps = 7/186 (3%)
Frame = +1
Query: 247 PSASSAIDFLSLCSRLKTTPRAGWGKRDVKNPESIADHMYRMGLMALIASDIAGVNRDKC 426
P + + FL++ LKT R GW + ESI+DHMYRMGL ++ +D V+R+KC
Sbjct: 24 PHPNYQLAFLNIIQLLKTQRRTGWVDHGIDPCESISDHMYRMGLTTMLITD-KNVDRNKC 82
Query: 427 IKMAIVHDIAEAIVGDITPSCGVSKEEKNRRESEALEHMCKLL---GGGERAEEIAELWR 597
I++A+VHD AE++VGDITP+ ++KEEK+RRE E ++++C+ + + EI + W
Sbjct: 83 IRIALVHDFAESLVGDITPNDPMTKEEKHRREFETVKYLCESIIRPCSESASREILDDWL 142
Query: 598 EYEANASPEAKVVKDFDKLELILQALEYEQEQG--KDLEEFFESTAGKFQTDIGKAWALE 771
YE E + VKD DK E+++Q EYEQ+ KDL++F +TD K W
Sbjct: 143 AYEKQTCLEGRYVKDIDKYEMLVQCFEYEQKYNGKKDLKQFL-GAINDIKTDEVKKWTQS 201
Query: 772 IASRRR 789
+ R+
Sbjct: 202 LLEDRQ 207
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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