BLASTX 7.6.2
Query= UN46793 /QuerySize=1157
(1156 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 90 2e-017
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 87 2e-016
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 87 2e-016
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 85 8e-016
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 85 1e-015
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 81 1e-014
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 80 2e-014
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 80 3e-014
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 79 4e-014
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 77 2e-013
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 76 4e-013
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 74 1e-012
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 73 3e-012
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 69 7e-011
sp|Q8LF65|ATL4G_ARATH RING-H2 finger protein ATL4G OS=Arabidopsi... 64 2e-009
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 59 5e-008
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 59 8e-008
sp|Q9C7I1|ATL1H_ARATH RING-H2 finger protein ATL1H OS=Arabidopsi... 58 1e-007
sp|Q6NKR1|ATL2H_ARATH RING-H2 finger protein ATL2H OS=Arabidopsi... 54 1e-006
sp|A8WWR3|HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-like prote... 53 3e-006
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 90 bits (222), Expect = 2e-017
Identities = 52/119 (43%), Positives = 70/119 (58%), Gaps = 11/119 (9%)
Frame = +3
Query: 426 GDYFIG-PGLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITEP----SLQCSVCLDE 590
GDY G GLD ++ L N G PPA KE + +LPTV +T+ L+C VC ++
Sbjct: 176 GDYAWGQTGLDAIVTQLLGQLEN-TGPPPADKEKITSLPTVTVTQEQVDMGLECPVCKED 234
Query: 591 F--EEEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVESRSRSLPESS 761
+ EEE +++PC H FH IVPWLELH +CPVCR S NG +S +S+S S+
Sbjct: 235 YTVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCR---KSLNGEDSTRQSQSTEASASN 290
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 87 bits (215), Expect = 2e-016
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 11/119 (9%)
Frame = +3
Query: 426 GDYFIG-PGLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDE 590
GDY G GLD ++ L N G PPA KE + +LPTV +T+ L+C VC ++
Sbjct: 177 GDYAWGQTGLDAIVTQLLGQLEN-TGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKED 235
Query: 591 F--EEEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVESRSRSLPESS 761
+ EE+ +++PC H FH IVPWLELH +CPVCR S NG +S +++S S+
Sbjct: 236 YTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCR---KSLNGEDSTRQTQSSEASASN 291
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 87 bits (214), Expect = 2e-016
Identities = 52/129 (40%), Positives = 66/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDEF 593
DY G GLD ++ L N G PPA KE + ALPTV +TE L+C VC D++
Sbjct: 178 DYAWGANGLDAIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDY 236
Query: 594 E--EEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVESRSRSLPESSNG 767
E +++PC H FH IVPWLE H SCPVCR L N + S SS+
Sbjct: 237 ALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVSFSSSSSS 296
Query: 768 NVVENVGNE 794
+ + NE
Sbjct: 297 SSSSSPSNE 305
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 85 bits (209), Expect = 8e-016
Identities = 55/127 (43%), Positives = 65/127 (51%), Gaps = 14/127 (11%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDEF 593
DY G GLD ++ L N G PPA KE + ALPTV +TE L+C VC D++
Sbjct: 181 DYAWGANGLDAIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDY 239
Query: 594 --EEEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSAN------GGESKVESRSRSL 749
E +++PC H FH IVPWLE H SCPVCR L N G S S S
Sbjct: 240 GLGEHVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQNTATDPPGLAGVSFSSSSSS 299
Query: 750 PESSNGN 770
SS GN
Sbjct: 300 SSSSPGN 306
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 85 bits (208), Expect = 1e-015
Identities = 50/129 (38%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDEF 593
DY G GLD ++ L N G PPA KE + ALPTV +TE L+C VC +++
Sbjct: 180 DYAWGANGLDTIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDY 238
Query: 594 E--EEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVESRSRSLPESSNG 767
E +++PC H FH IVPWLE H SCPVCR L N + SS+
Sbjct: 239 ALGESVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVGFSSSSSS 298
Query: 768 NVVENVGNE 794
+ + NE
Sbjct: 299 SSSSSPSNE 307
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 81 bits (199), Expect = 1e-014
Identities = 43/94 (45%), Positives = 59/94 (62%), Gaps = 6/94 (6%)
Frame = +3
Query: 447 GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKIT----EPSLQCSVCLDEFEEE--AK 608
GLD+ +D +++ PPA K VV +LP V I+ + ++C VCL EFEE+ +
Sbjct: 34 GLDIDSGSFDLSDWDQRLPPPAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEEQESVR 93
Query: 609 EMPCKHKFHVKRIVPWLELHSSCPVCRFELPSAN 710
EMPCKH FH I+PWL +SCP+CR ELP+ N
Sbjct: 94 EMPCKHLFHTGCILPWLNKTNSCPLCRLELPTDN 127
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 80 bits (197), Expect = 2e-014
Identities = 43/101 (42%), Positives = 57/101 (56%), Gaps = 8/101 (7%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDEF 593
DY G GLD ++ L N G PPA E + ALPT++ITE L+C VC +++
Sbjct: 176 DYAWGANGLDTIITQLL-NQFENTGPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDY 234
Query: 594 E--EEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSAN 710
E +++PC H FH I+PWLE H +CPVCR L N
Sbjct: 235 TVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQN 275
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 80 bits (195), Expect = 3e-014
Identities = 49/124 (39%), Positives = 66/124 (53%), Gaps = 13/124 (10%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITE----PSLQCSVCLDEF 593
DY G GLD ++ L N G PPA E + ALPT++ITE L+C VC +++
Sbjct: 177 DYAWGANGLDTIITQLL-NQFENTGPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDY 235
Query: 594 E--EEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSAN-----GGESKVESRSRSLP 752
E +++PC H FH I+PWLE H +CPVCR L N G S++ S S
Sbjct: 236 TVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQNTATNPPGLSEMTFSSSSTS 295
Query: 753 ESSN 764
SS+
Sbjct: 296 SSSS 299
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 79 bits (194), Expect = 4e-014
Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 8/101 (7%)
Frame = +3
Query: 429 DYFIGP-GLDLLLQHLAENDPNRQGTPPARKEVVDALPTVKITEP----SLQCSVCLDEF 593
DY G GLD ++ L N G PPA + + ALPT++ITE L+C VC +++
Sbjct: 177 DYAWGANGLDTIITQLL-NQFENTGPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDY 235
Query: 594 E--EEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSAN 710
E +++PC H FH I+PWLE H +CPVCR L N
Sbjct: 236 TVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQN 276
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 77 bits (189), Expect = 2e-013
Identities = 38/71 (53%), Positives = 49/71 (69%), Gaps = 4/71 (5%)
Frame = +3
Query: 504 PPARKEVVDALP--TVKITEPSLQCSVCLDEFEEE--AKEMPCKHKFHVKRIVPWLELHS 671
PPA K VV+ LP ++ ++ L+C VCL EFEEE A EMPC H FH I+PWL +
Sbjct: 52 PPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTN 111
Query: 672 SCPVCRFELPS 704
SCP+CR+ELP+
Sbjct: 112 SCPLCRYELPT 122
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 76 bits (186), Expect = 4e-013
Identities = 37/71 (52%), Positives = 48/71 (67%), Gaps = 4/71 (5%)
Frame = +3
Query: 504 PPARKEVVDALP--TVKITEPSLQCSVCLDEFEEEAK--EMPCKHKFHVKRIVPWLELHS 671
PPA K VV++LP ++ ++ L+C VCL EFEEE EMPC H FH I+PWL +
Sbjct: 64 PPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTN 123
Query: 672 SCPVCRFELPS 704
SCP+CR ELP+
Sbjct: 124 SCPLCRHELPT 134
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 74 bits (181), Expect = 1e-012
Identities = 37/71 (52%), Positives = 47/71 (66%), Gaps = 4/71 (5%)
Frame = +3
Query: 504 PPARKEVVDALP--TVKITEPSLQCSVCLDEFEEE--AKEMPCKHKFHVKRIVPWLELHS 671
PPA K V+ LP ++ ++ L+C VCL EFEEE A EMPC H FH I+PWL +
Sbjct: 52 PPAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTN 111
Query: 672 SCPVCRFELPS 704
SCP+CR ELP+
Sbjct: 112 SCPLCRHELPT 122
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 73 bits (178), Expect = 3e-012
Identities = 37/71 (52%), Positives = 46/71 (64%), Gaps = 4/71 (5%)
Frame = +3
Query: 504 PPARKEVVDALPTVKIT--EPSLQCSVCLDEFEEEAK--EMPCKHKFHVKRIVPWLELHS 671
PPA K VV++LP I+ + L+C VCL EFE E EMPC H FH I+PWL +
Sbjct: 64 PPAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTN 123
Query: 672 SCPVCRFELPS 704
SCP+CR ELP+
Sbjct: 124 SCPLCRHELPT 134
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 69 bits (166), Expect = 7e-011
Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 7/91 (7%)
Frame = +3
Query: 492 RQGTPPARKEVVDALPTVKIT----EPSLQCSVCLD--EFEEEAKEMPCKHKFHVKRIVP 653
R+G PPA K ++AL T +++ E + C+VC D E K++PC H +H IVP
Sbjct: 227 RRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVP 286
Query: 654 WLELHSSCPVCRFELPSANGGESKVESRSRS 746
WL +SCPVCRF+L + E + E + R+
Sbjct: 287 WLGTRNSCPVCRFQL-ETDDAEYEEERKKRT 316
>sp|Q8LF65|ATL4G_ARATH RING-H2 finger protein ATL4G OS=Arabidopsis thaliana
GN=ATL4G PE=2 SV=2
Length = 235
Score = 64 bits (154), Expect = 2e-009
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Frame = +3
Query: 561 SLQCSVCLDEFE--EEAKEMP-CKHKFHVKRIVPWLELHSSCPVCRFEL-PSANGGESKV 728
+++CSVCL EF+ E + MP CKH FHV I W HSSCP+CR ++ P A G +S +
Sbjct: 73 AMECSVCLSEFKDNESGRVMPNCKHTFHVHCIDMWFHSHSSCPLCRSQIEPFAGGVKSSM 132
Query: 729 ESRSRSLPESSNGNVVENVGNEERG 803
+ + S+ + G+ + G E G
Sbjct: 133 DEVAISISDPVYGDTNHHEGTETTG 157
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 59 bits (142), Expect = 5e-008
Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +3
Query: 567 QCSVCLDE--FEEEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVESRS 740
+C +C + ++ +E+PCKH FH + PWL+ H+SCP+CR ELP+ + + R
Sbjct: 229 ECCICKENLVIGDKMQELPCKHTFHPPCLKPWLDEHNSCPICRHELPTDDQKYENWKERE 288
Query: 741 RSLPESSNG 767
+ E G
Sbjct: 289 KEAEEERKG 297
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 59 bits (140), Expect = 8e-008
Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 6/71 (8%)
Frame = +3
Query: 504 PPARKEVVDALPTVKITEP----SLQCSVCLDEFEEEAKE--MPCKHKFHVKRIVPWLEL 665
P A K + LP +I + L+CSVC + EE K +PCKH+FH + I+ WL+
Sbjct: 44 PEASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKK 103
Query: 666 HSSCPVCRFEL 698
+SCP+CR+EL
Sbjct: 104 TNSCPLCRYEL 114
>sp|Q9C7I1|ATL1H_ARATH RING-H2 finger protein ATL1H OS=Arabidopsis thaliana
GN=ATL1H PE=2 SV=1
Length = 327
Score = 58 bits (138), Expect = 1e-007
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Frame = +3
Query: 543 VKITEPSLQCSVCLDEFEEEAK---EMPCKHKFHVKRIVPWLELHSSCPVCRFELPSANG 713
+KI + ++C++CL+EFE+E PC H FH I WL S+CPVCR LP G
Sbjct: 119 LKIGKGGVECAICLNEFEDEETLRLMPPCSHAFHASCIDVWLSSRSTCPVCRASLPPKPG 178
Query: 714 GE 719
+
Sbjct: 179 SD 180
>sp|Q6NKR1|ATL2H_ARATH RING-H2 finger protein ATL2H OS=Arabidopsis thaliana
GN=ATL2H PE=2 SV=1
Length = 254
Score = 54 bits (129), Expect = 1e-006
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Frame = +3
Query: 567 QCSVCLDEFEEEAKE---MPCKHKFHVKRIVPWLELHSSCPVCRFELPSANGGESKVES 734
+C++CL EF +E C+H FH I W ELH +CPVCR EL G ++ES
Sbjct: 102 ECAICLSEFSDEDTVRLITVCRHPFHSNCIDLWFELHKTCPVCRCELDPGMIGSGRLES 160
>sp|A8WWR3|HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-like protein 1
OS=Caenorhabditis briggsae GN=hrdl-1 PE=3 SV=1
Length = 578
Score = 53 bits (126), Expect = 3e-006
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +3
Query: 516 KEVVDALPTVKITEPSLQCSVCLDEFEEEAKEMPCKHKFHVKRIVPWLELHSSCPVCRFE 695
+ + A P+VK +C VC E ++ +PC H+FH ++ WL SSCP CR+
Sbjct: 332 EHIESAYPSVKAANSDDRCIVCW-ELLGTSRRLPCSHQFHDWCLMWWLAQDSSCPTCRYV 390
Query: 696 LPSANGGESKVESRSRSLPESSNG 767
+PS S+ +S + + NG
Sbjct: 391 IPSPQEEASRTDSGNGNTMFRFNG 414
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,418,403,310
Number of Sequences: 518415
Number of Extensions: 174418403310
Number of Successful Extensions: 1059328112
Number of sequences better than 0.0: 0
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