BLASTX 7.6.2
Query= UN47223 /QuerySize=1422
(1421 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Dani... 58 1e-007
sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo... 58 1e-007
sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus ... 58 1e-007
sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos ... 58 2e-007
sp|Q99M02|MARH2_MOUSE E3 ubiquitin-protein ligase MARCH2 OS=Mus ... 58 2e-007
sp|Q5I0I2|MARH2_RAT E3 ubiquitin-protein ligase MARCH2 OS=Rattus... 58 2e-007
sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos ... 58 2e-007
sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo... 58 2e-007
sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus ... 58 2e-007
sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus... 58 2e-007
sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 56 7e-007
sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 56 7e-007
sp|Q5PQ35|MARH2_XENLA E3 ubiquitin-protein ligase MARCH2 OS=Xeno... 55 9e-007
sp|Q28EX7|MARH2_XENTR E3 ubiquitin-protein ligase MARCH2 OS=Xeno... 55 9e-007
sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo... 55 1e-006
sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus ... 55 1e-006
sp|Q9P0N8|MARH2_HUMAN E3 ubiquitin-protein ligase MARCH2 OS=Homo... 54 2e-006
>sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Danio rerio
GN=march4 PE=2 SV=1
Length = 421
Score = 58 bits (139), Expect = 1e-007
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Frame = +1
Query: 241 SIESSGESSRTQGTTIISSTTTTFTKSKDDKTVQVEE-LDVEDEEEPLIQSAECRICQDE 417
++++ G T T + S+D +++E L + + +++ CRIC
Sbjct: 90 ALDTRGPDDWTHSVVDPPRTLDCCSSSEDCSKEKLDERLSLNSCTDSGVRTPLCRICFQG 149
Query: 418 DSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQ 549
L SPC CSGS++ H C+ +W +E+G CE+C+ YQ
Sbjct: 150 PEQGELLSPCRCSGSVRCTHEPCLIKWISERGSWSCELCYYKYQ 193
>sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo sapiens
GN=MARCH9 PE=1 SV=2
Length = 346
Score = 58 bits (139), Expect = 1e-007
Identities = 23/69 (33%), Positives = 39/69 (56%)
Frame = +1
Query: 343 VEELDVEDEEEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTI 522
++ L + + +++ +CRIC L SPC C GS++ H+ C+ RW +E+G
Sbjct: 92 LDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWS 151
Query: 523 CEICHKSYQ 549
CE+C+ YQ
Sbjct: 152 CELCYFKYQ 160
>sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus musculus
GN=March9 PE=2 SV=1
Length = 348
Score = 58 bits (139), Expect = 1e-007
Identities = 23/69 (33%), Positives = 39/69 (56%)
Frame = +1
Query: 343 VEELDVEDEEEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTI 522
++ L + + +++ +CRIC L SPC C GS++ H+ C+ RW +E+G
Sbjct: 92 LDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWS 151
Query: 523 CEICHKSYQ 549
CE+C+ YQ
Sbjct: 152 CELCYFKYQ 160
>sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos taurus
GN=MARCH2 PE=2 SV=1
Length = 245
Score = 58 bits (138), Expect = 2e-007
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSY 546
CRIC + + ++L SPC CSG+L H+ C++RW + + CE+CH +
Sbjct: 64 CRICHEGANGESLLSPCGCSGTLGAVHKSCLERWLSSSNTSYCELCHTEF 113
>sp|Q99M02|MARH2_MOUSE E3 ubiquitin-protein ligase MARCH2 OS=Mus musculus
GN=March2 PE=2 SV=1
Length = 246
Score = 58 bits (138), Expect = 2e-007
Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQPGYTAPPPP 576
CRIC + + +NL SPC C+G+L H+ C+++W + + CE+CH + P
Sbjct: 64 CRICHEGANGENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFA---VEKRPR 120
Query: 577 PADETVIDIG 606
P E + D G
Sbjct: 121 PLTEWLKDPG 130
>sp|Q5I0I2|MARH2_RAT E3 ubiquitin-protein ligase MARCH2 OS=Rattus norvegicus
GN=March2 PE=1 SV=1
Length = 246
Score = 58 bits (138), Expect = 2e-007
Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQPGYTAPPPP 576
CRIC + + +NL SPC C+G+L H+ C+++W + + CE+CH + P
Sbjct: 64 CRICHEGANGENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFA---VEKRPR 120
Query: 577 PADETVIDIG 606
P E + D G
Sbjct: 121 PLTEWLKDPG 130
>sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos taurus
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 58 bits (138), Expect = 2e-007
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 370 EEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
+ P CRIC + S ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 62 QSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo sapiens
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 58 bits (138), Expect = 2e-007
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 370 EEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
+ P CRIC + S ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 62 QSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus musculus
GN=March3 PE=2 SV=1
Length = 218
Score = 58 bits (138), Expect = 2e-007
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 370 EEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
+ P CRIC + S ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 62 QSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus norvegicus
GN=March3 PE=1 SV=1
Length = 253
Score = 58 bits (138), Expect = 2e-007
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 370 EEPLIQSAECRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
+ P CRIC + S ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 62 QSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xenopus laevis
GN=march3 PE=2 SV=1
Length = 252
Score = 56 bits (133), Expect = 7e-007
Identities = 19/47 (40%), Positives = 30/47 (63%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
CRIC + + ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 70 CRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 116
>sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xenopus tropicalis
GN=march3 PE=2 SV=1
Length = 251
Score = 56 bits (133), Expect = 7e-007
Identities = 19/47 (40%), Positives = 30/47 (63%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICH 537
CRIC + + ++L SPC C+G+L HR C++ W + + CE+CH
Sbjct: 69 CRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 115
>sp|Q5PQ35|MARH2_XENLA E3 ubiquitin-protein ligase MARCH2 OS=Xenopus laevis
GN=march2 PE=2 SV=1
Length = 246
Score = 55 bits (132), Expect = 9e-007
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQPGYTAPPPP 576
CRIC + + + L SPC C+G+L H+ C+++W + + CE+CH + P
Sbjct: 64 CRICHEGGNGERLLSPCDCTGTLGTVHKTCLEKWLSSSNTSYCELCHTEFA---VERRPR 120
Query: 577 PADETVIDIG 606
P E + D G
Sbjct: 121 PVTEWLKDPG 130
>sp|Q28EX7|MARH2_XENTR E3 ubiquitin-protein ligase MARCH2 OS=Xenopus tropicalis
GN=march2 PE=2 SV=1
Length = 246
Score = 55 bits (132), Expect = 9e-007
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQPGYTAPPPP 576
CRIC + + + L SPC C+G+L H+ C+++W + + CE+CH + P
Sbjct: 64 CRICHEGGNGERLLSPCDCTGTLGTVHKTCLEKWLSSSNTSYCELCHTEFA---VERRPR 120
Query: 577 PADETVIDIG 606
P E + D G
Sbjct: 121 PVTEWLKDPG 130
>sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo sapiens
GN=MARCH4 PE=2 SV=2
Length = 410
Score = 55 bits (130), Expect = 1e-006
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Frame = +1
Query: 256 GESSRTQGTTIISSTTTTFTKSKDDKTVQVEELDVEDEEEPLIQSAECRICQDEDSVKNL 435
G ++ + + S+++ F K K + + PL CRIC L
Sbjct: 121 GPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPL-----CRICFQGPEQGEL 175
Query: 436 ESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSY 546
SPC C GS+K H+ C+ +W +E+G CE+C+ Y
Sbjct: 176 LSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKY 212
>sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus musculus
GN=March4 PE=2 SV=3
Length = 409
Score = 55 bits (130), Expect = 1e-006
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 5/103 (4%)
Frame = +1
Query: 238 GSIESSGESSRTQGTTIISSTTTTFTKSKDDKTVQVEELDVEDEEEPLIQSAECRICQDE 417
G + G ++ + + S+++ F K K + + PL CRIC
Sbjct: 114 GDDDWDGPATGPPASLLSSASSDEFCKEKTEDCYSLGSSLDSGMRTPL-----CRICFQG 168
Query: 418 DSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSY 546
L SPC C GS+K H+ C+ +W +E+G CE+C+ Y
Sbjct: 169 PEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKY 211
>sp|Q9P0N8|MARH2_HUMAN E3 ubiquitin-protein ligase MARCH2 OS=Homo sapiens
GN=MARCH2 PE=1 SV=1
Length = 246
Score = 54 bits (129), Expect = 2e-006
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Frame = +1
Query: 397 CRICQDEDSVKNLESPCSCSGSLKYAHRKCVQRWCNEKGDTICEICHKSYQPGYTAPPPP 576
CRIC + + + L SPC C+G+L H+ C+++W + + CE+CH + P
Sbjct: 64 CRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFA---VEKRPR 120
Query: 577 PADETVIDIG 606
P E + D G
Sbjct: 121 PLTEWLKDPG 130
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 177,416,216,708
Number of Sequences: 518415
Number of Extensions: 177416216708
Number of Successful Extensions: 1076203161
Number of sequences better than 0.0: 0
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