BLASTX 7.6.2
Query= UN47251 /QuerySize=907
(906 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99MM4|TRAD1_RAT TRAF-type zinc finger domain-containing prot... 108 6e-023
sp|Q4R970|TRAD1_MACFA TRAF-type zinc finger domain-containing pr... 107 2e-022
sp|Q3UDK1|TRAD1_MOUSE TRAF-type zinc finger domain-containing pr... 106 3e-022
sp|O14545|TRAD1_HUMAN TRAF-type zinc finger domain-containing pr... 105 7e-022
sp|Q58D05|TRAD1_BOVIN TRAF-type zinc finger domain-containing pr... 103 3e-021
sp|Q58DH1|XAF1_BOVIN XIAP-associated factor 1 OS=Bos taurus GN=X... 98 8e-020
sp|Q6GPH4|XAF1_HUMAN XIAP-associated factor 1 OS=Homo sapiens GN... 97 1e-019
sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2 OS=Mus mu... 54 2e-006
sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 OS=Mus mu... 52 5e-006
>sp|Q99MM4|TRAD1_RAT TRAF-type zinc finger domain-containing protein 1 OS=Rattus
norvegicus GN=Trafd1 PE=2 SV=2
Length = 576
Score = 108 bits (269), Expect = 6e-023
Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
Frame = +2
Query: 185 VCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKETI 364
+C++C ++IP N +H +HC RN+ C +C + PK H + H V C C + +
Sbjct: 12 LCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHVATEHCQVTCK-CNKKL 70
Query: 365 DREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRETFN 544
++ H E CP R+ C+ C+ L V L EH++ CG RTELC C V ++E
Sbjct: 71 EKRQLKQHVETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELQT 130
Query: 545 HETKCPGSVLNTVESSRRVPRPA 613
H C G V S VP A
Sbjct: 131 HPAVC-GRVEEEKRSEAAVPPEA 152
>sp|Q4R970|TRAD1_MACFA TRAF-type zinc finger domain-containing protein 1
OS=Macaca fascicularis GN=TRAFD1 PE=2 SV=1
Length = 582
Score = 107 bits (265), Expect = 2e-022
Identities = 43/127 (33%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
Frame = +2
Query: 179 TIVCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKE 358
T +C++C ++IP N +H +HC RN+ C IC + PK + H + H V C C +
Sbjct: 10 TRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMAAEHCQVTCK-CNK 68
Query: 359 TIDREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRET 538
+++ + H E CP R+ C+ C+ L + L EH++ CG RTELC C V +++
Sbjct: 69 KLEKRLLKKHEETECPLRLAVCQHCDLELSILKLKEHEDYCGARTELCGNCGRNVLVKDL 128
Query: 539 FNHETKC 559
H C
Sbjct: 129 KTHPEVC 135
>sp|Q3UDK1|TRAD1_MOUSE TRAF-type zinc finger domain-containing protein 1 OS=Mus
musculus GN=Trafd1 PE=1 SV=1
Length = 580
Score = 106 bits (263), Expect = 3e-022
Identities = 47/143 (32%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
Frame = +2
Query: 185 VCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKETI 364
+C++C ++IP N +H +HC RN+ C +C + PK H + H V C C + +
Sbjct: 12 LCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCK-CNKKL 70
Query: 365 DREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRETFN 544
++ H E CP R+ C+ C+ L V L EH++ CG RTELC C V ++E
Sbjct: 71 EKRQLKQHAETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELKT 130
Query: 545 HETKCPGSVLNTVESSRRVPRPA 613
H C G V + +P A
Sbjct: 131 HPEVC-GRVEEEKRTEAAIPPEA 152
>sp|O14545|TRAD1_HUMAN TRAF-type zinc finger domain-containing protein 1 OS=Homo
sapiens GN=TRAFD1 PE=1 SV=1
Length = 582
Score = 105 bits (260), Expect = 7e-022
Identities = 42/127 (33%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
Frame = +2
Query: 179 TIVCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKE 358
T +C++C ++IP N +H +HC RN+ C C + PK + H + H V C C +
Sbjct: 10 TRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCK-CNK 68
Query: 359 TIDREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRET 538
+++ + H E CP R+ C+ C+ L + L EH++ CG RTELC C V +++
Sbjct: 69 KLEKRLLKKHEETECPLRLAVCQHCDLELSILKLKEHEDYCGARTELCGNCGRNVLVKDL 128
Query: 539 FNHETKC 559
H C
Sbjct: 129 KTHPEVC 135
>sp|Q58D05|TRAD1_BOVIN TRAF-type zinc finger domain-containing protein 1 OS=Bos
taurus GN=TRAFD1 PE=2 SV=1
Length = 580
Score = 103 bits (255), Expect = 3e-021
Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
Frame = +2
Query: 179 TIVCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKE 358
T +C++C ++IP N +H +HC RN+ C +C + PK + H + H V C C +
Sbjct: 10 TRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCK-CNK 68
Query: 359 TIDREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRET 538
+++ H E CP R+ C+ C+ L + L +H++ CG RTELC C V +++
Sbjct: 69 KLEKRQLKKHEETECPLRLALCQHCDLELSVLKLKDHEDYCGARTELCGTCGRNVLVKDL 128
Query: 539 FNHETKC 559
H C
Sbjct: 129 KTHPEVC 135
>sp|Q58DH1|XAF1_BOVIN XIAP-associated factor 1 OS=Bos taurus GN=XAF1 PE=2 SV=2
Length = 297
Score = 98 bits (242), Expect = 8e-020
Identities = 48/144 (33%), Positives = 74/144 (51%), Gaps = 5/144 (3%)
Frame = +2
Query: 185 VCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKETI 364
VC +C R + + ++ LH HC L C C + V + +EH H V C+MC++++
Sbjct: 7 VCRNCKRRVASNHLGLHEAHCLMYLVLCPECKEPVLQHEMEEHCQGGHQQVGCAMCQQSV 66
Query: 365 DREVFNSHTEEICPKRMVTCEFCEFP--LPAVDLPEHQEVCGNRTELCYQCNSYVRLRET 538
+ +SH + C +R V C+FC+ L VDL EH CG +TELC C +V LR
Sbjct: 67 PKHSLDSHEAQECQERPVECQFCQLAVRLNKVDLHEHH--CGQQTELCPDCGQHVMLRVL 124
Query: 539 FNHETKCPGSVLNTVESSRRVPRP 610
H +C L ++ + +P P
Sbjct: 125 ARHREECQREQLR-LQKGKSIPVP 147
>sp|Q6GPH4|XAF1_HUMAN XIAP-associated factor 1 OS=Homo sapiens GN=XAF1 PE=1
SV=1
Length = 301
Score = 97 bits (241), Expect = 1e-019
Identities = 42/125 (33%), Positives = 63/125 (50%)
Frame = +2
Query: 185 VCNHCDRDIPAPNIDLHRVHCARNLEKCKICGDMVPKKHAQEHFSNTHAPVPCSMCKETI 364
VC +C R + + N LH +C R L C C + VPK+ +EH H V C+MC++++
Sbjct: 7 VCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSM 66
Query: 365 DREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSYVRLRETFN 544
+ H C +R V C+FC+ + L H+ CG+RTELC C ++ R
Sbjct: 67 QKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQ 126
Query: 545 HETKC 559
H C
Sbjct: 127 HRDVC 131
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2 OS=Mus musculus GN=Traf2
PE=1 SV=1
Length = 501
Score = 54 bits (127), Expect = 2e-006
Identities = 28/74 (37%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +2
Query: 341 CSMCKETIDREVFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELCYQCNSY 520
C CK + HTE+ CPKR ++C+ C P VDL H EVC C C
Sbjct: 136 CPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKK 195
Query: 521 VRLRETF-NHETKC 559
RETF +H C
Sbjct: 196 KIPRETFQDHVRAC 209
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 OS=Mus musculus GN=Traf4
PE=2 SV=1
Length = 470
Score = 52 bits (123), Expect = 5e-006
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 11/125 (8%)
Frame = +2
Query: 212 PAPNIDLH----RVHCARNLEKCKICGDMVPKKHAQEHFSN-THAPVPC-SMCKETIDRE 373
P P +++ + C + E C+ G P +H Q H + + VPC + C + R
Sbjct: 68 PDPELEVQVLGLAIRCIHSEEGCRWSG---PLRHLQGHLNTCSFNVVPCPNRCPAKLSRR 124
Query: 374 VFNSHTEEICPKRMVTCEFCEFPLPAVDLPEHQEVCGNRTELC-YQCNSYVRLRETFNHE 550
+H + CPKR + CEFC H+ VC + C +C + + R H
Sbjct: 125 DLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVFCENKCGARMMRRLLAQHA 184
Query: 551 T-KCP 562
T +CP
Sbjct: 185 TSECP 189
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 177,416,216,708
Number of Sequences: 518415
Number of Extensions: 177416216708
Number of Successful Extensions: 1076203161
Number of sequences better than 0.0: 0
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