BLASTX 7.6.2

Query= UN48497 /QuerySize=639
        (638 letters)

Database: UniProt/SwissProt;
          518,415 sequences; 182,829,261 total letters
                                                                  Score    E
Sequences producing significant alignments:                       (bits) Value

sp|O15514|RPB4_HUMAN DNA-directed RNA polymerase II subunit RPB4...    103   1e-021
sp|Q9D7M8|RPB4_MOUSE DNA-directed RNA polymerase II subunit RPB4...    103   1e-021
sp|Q9VEA5|RPB4_DROME DNA-directed RNA polymerase II 16 kDa polyp...     91   5e-018
sp|Q54S04|RPB4_DICDI DNA-directed RNA polymerase II subunit rpb4...     78   4e-014
sp|O74825|RPB4_SCHPO DNA-directed RNA polymerase II subunit rpb4...     66   1e-010

>sp|O15514|RPB4_HUMAN DNA-directed RNA polymerase II subunit RPB4 OS=Homo
        sapiens GN=POLR2D PE=1 SV=1

          Length = 142

 Score =  103 bits (256), Expect = 1e-021
 Identities = 52/126 (41%), Positives = 86/126 (68%), Gaps = 5/126 (3%)
 Frame = +3

Query:  87 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 266
           EE+A++L    EF  A+ L+N EV ++LEH+ +Q +   ++   ++S+VF K+L Y  RF
Sbjct:  14 EEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDE--QELSEVFMKTLNYTARF 71

Query: 267 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 446
           SR+KN + +  VR +L + +L +FEL  L NLCPETAEE+ A++PSL+ +     DE ++
Sbjct:  72 SRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGR---FEDEELQ 128

Query: 447 KMLNDL 464
           ++L+D+
Sbjct: 129 QILDDI 134

>sp|Q9D7M8|RPB4_MOUSE DNA-directed RNA polymerase II subunit RPB4 OS=Mus
        musculus GN=Polr2d PE=2 SV=2

          Length = 142

 Score =  103 bits (256), Expect = 1e-021
 Identities = 52/126 (41%), Positives = 86/126 (68%), Gaps = 5/126 (3%)
 Frame = +3

Query:  87 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 266
           EE+A++L    EF  A+ L+N EV ++LEH+ +Q +   ++   ++S+VF K+L Y  RF
Sbjct:  14 EEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDE--QELSEVFMKTLNYTARF 71

Query: 267 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 446
           SR+KN + +  VR +L + +L +FEL  L NLCPETAEE+ A++PSL+ +     DE ++
Sbjct:  72 SRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGR---FEDEELQ 128

Query: 447 KMLNDL 464
           ++L+D+
Sbjct: 129 QILDDI 134

>sp|Q9VEA5|RPB4_DROME DNA-directed RNA polymerase II 16 kDa polypeptide
        OS=Drosophila melanogaster GN=Rpb4 PE=1 SV=5

          Length = 139

 Score =  91 bits (224), Expect = 5e-018
 Identities = 46/126 (36%), Positives = 78/126 (61%), Gaps = 5/126 (3%)
 Frame = +3

Query:  87 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 266
           +E+AA+L+   EF  A+ L+  EV ++L+H+  Q +   E+   + S+VF K+  Y   F
Sbjct:  11 DEDAADLQFPKEFENAETLLISEVHMLLDHRKRQNESADEE--QEFSEVFMKTYAYTDSF 68

Query: 267 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 446
            ++KN + +   R +L + +L +FEL  LGNLCPE  EEA A++PSL+ +     DE + 
Sbjct:  69 RKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGR---FEDEELR 125

Query: 447 KMLNDL 464
           ++L+D+
Sbjct: 126 QILDDI 131

>sp|Q54S04|RPB4_DICDI DNA-directed RNA polymerase II subunit rpb4
        OS=Dictyostelium discoideum GN=polr2d PE=3 SV=1

          Length = 155

 Score =  78 bits (191), Expect = 4e-014
 Identities = 36/85 (42%), Positives = 58/85 (68%), Gaps = 4/85 (4%)
 Frame = +3

Query: 213 MNQVSQVFEKSLQYVKRFSRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVA 392
           +N + + F K+L Y ++FSRYKN  +++QVR  LS+  L EFE+  L NLCPE ++EA +
Sbjct:  69 INDIIRTFHKTLAYAEKFSRYKNKTSIKQVRTALSKQNLEEFEIASLANLCPEISDEAKS 128

Query: 393 MVPSLKTKGRAHSDEAIEKMLNDLS 467
           ++PSLK       D+ ++ +L++LS
Sbjct: 129 LIPSLKKM----EDDELQAILDELS 149

>sp|O74825|RPB4_SCHPO DNA-directed RNA polymerase II subunit rpb4
        OS=Schizosaccharomyces pombe GN=rpb4 PE=1 SV=1

          Length = 135

 Score =  66 bits (160), Expect = 1e-010
 Identities = 42/132 (31%), Positives = 73/132 (55%), Gaps = 5/132 (3%)
 Frame = +3

Query:  87 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 266
           EE+AA+LK+G EF     L   E  +++E    Q  + +   +  ++ V +K++ Y   F
Sbjct:   7 EEDAAQLKLGPEFENEDMLTVSEAKILIETVLAQRARETNGEI-PMTDVMKKTVAYFNVF 65

Query: 267 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 446
           +R+K  +A      IL  ++  +FE   LG LC E AEEA  ++PSL  K     D+ ++
Sbjct:  66 ARFKTAEATYACERILG-NRFHKFERAQLGTLCCEDAEEARTLIPSLANK---IDDQNLQ 121

Query: 447 KMLNDLSLVKRF 482
            +L++LS +++F
Sbjct: 122 GILDELSTLRKF 133

  Database: UniProt/SwissProt
    Posted date:  Sat Aug 07 14:36:18 2010
  Number of letters in database: 182,829,261
  Number of sequences in database:  518,415

Lambda     K     H
   0.267   0.041    0.140
Gapped
Lambda     K     H
   0.267   0.041    0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 182,561,833,118
Number of Sequences: 518415
Number of Extensions: 182561833118
Number of Successful Extensions: 1116914633
Number of sequences better than 0.0: 0