BLASTX 7.6.2
Query= UN48932 /QuerySize=1227
(1226 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54N38|UCHL5_DICDI Ubiquitin carboxyl-terminal hydrolase isoz... 319 3e-086
sp|Q9Y5K5|UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isoz... 314 1e-084
sp|Q9WUP7|UCHL5_MOUSE Ubiquitin carboxyl-terminal hydrolase isoz... 314 1e-084
sp|Q06AT3|UCHL5_PIG Ubiquitin carboxyl-terminal hydrolase isozym... 313 2e-084
sp|Q9XSJ0|UCHL5_BOVIN Ubiquitin carboxyl-terminal hydrolase isoz... 261 8e-069
sp|Q9UUB6|UBLH2_SCHPO Ubiquitin carboxyl-terminal hydrolase 2 OS... 242 4e-063
sp|Q92560|BAP1_HUMAN Ubiquitin carboxyl-terminal hydrolase BAP1 ... 205 5e-052
sp|D3ZHS6|BAP1_RAT Ubiquitin carboxyl-terminal hydrolase BAP1 OS... 205 9e-052
sp|Q99PU7|BAP1_MOUSE Ubiquitin carboxyl-terminal hydrolase BAP1 ... 204 1e-051
sp|Q66JB6|BAP1_XENTR Ubiquitin carboxyl-terminal hydrolase BAP1 ... 202 5e-051
sp|Q52L14|BAP1_XENLA Ubiquitin carboxyl-terminal hydrolase BAP1 ... 202 6e-051
sp|Q5F3N6|BAP1_CHICK Ubiquitin carboxyl-terminal hydrolase BAP1 ... 201 1e-050
sp|A1L2G3|BAP1_DANRE Ubiquitin carboxyl-terminal hydrolase BAP1 ... 195 6e-049
sp|A2VDM8|BAP1_BOVIN Ubiquitin carboxyl-terminal hydrolase BAP1 ... 190 2e-047
sp|C4A0D9|BAP1_BRAFL Ubiquitin carboxyl-terminal hydrolase BAP1 ... 184 1e-045
sp|Q17N72|CALYP_AEDAE Ubiquitin carboxyl-terminal hydrolase caly... 176 4e-043
sp|B0W2R4|CALYP_CULQU Ubiquitin carboxyl-terminal hydrolase caly... 154 1e-036
>sp|Q54N38|UCHL5_DICDI Ubiquitin carboxyl-terminal hydrolase isozyme L5
OS=Dictyostelium discoideum GN=uch2 PE=3 SV=1
Length = 343
Score = 319 bits (817), Expect = 3e-086
Identities = 167/336 (49%), Positives = 223/336 (66%), Gaps = 23/336 (6%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDRP 287
WCTIESDPGVFTELI ++ VK +QVEELY+LD + L+PV GLIFLFKW+ +++
Sbjct: 7 WCTIESDPGVFTELITKIGVKDIQVEELYTLDSSEYDRLKPVLGLIFLFKWEK--EEENR 64
Query: 288 TIQDPVSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKNFPSDLKGLAI 467
TI D N+FFANQVI NACATQAILS+LLNS +++G ELS K F +FP +KG AI
Sbjct: 65 TISDN-ENIFFANQVIQNACATQAILSVLLNSEGIELGEELSNFKSFVGDFPPMMKGEAI 123
Query: 468 NNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPISLG 647
NSE I+ HNSF +PF+ ++K K D +HFIS+IP G +YELDGLK+GP LG
Sbjct: 124 GNSELIKETHNSFTVQDPFIFSKKK-NRKPSDAFHFISFIPFQGKVYELDGLKKGPYCLG 182
Query: 648 PCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQREQM 827
C D WL++ P IQ+R+E+YSQ EIRFNL+AVIKNR+ ++ L++++ +
Sbjct: 183 DCTPD----NWLEIATPFIQKRMEKYSQGEIRFNLMAVIKNRQTTLQEKILTLEKKKNDL 238
Query: 828 VQELAGVEKSRAG---------------ELEVLIGEVRSGIEAVSDKIVMEEEKFMKWKT 962
+L+ + G +L +I V + IE +++I+ME+EKF WK
Sbjct: 239 EIKLSELNSGSGGDNKEESGGATPTTKEDLNFMINVVNNDIEEANNEILMEQEKFRNWKD 298
Query: 963 ENIRRKHNYIPFLFNFLKLLAEKKQLKPLIEKAKKQ 1070
ENIRRKHN+ P + N +K LAEK L+PLI+KAK Q
Sbjct: 299 ENIRRKHNFTPLILNLIKGLAEKDNLQPLIQKAKDQ 334
>sp|Q9Y5K5|UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo
sapiens GN=UCHL5 PE=1 SV=3
Length = 329
Score = 314 bits (802), Expect = 1e-084
Identities = 164/336 (48%), Positives = 232/336 (69%), Gaps = 19/336 (5%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDRP 287
WC +ESDPGVFTELI+ +G QVEE++SL+ ++ L+PV+GLIFLFKWQ G +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 288 TIQDP-VSNLFFANQVINNACATQAILSILLN--SPDVDIGPELSTLKEFTKNFPSDLKG 458
+QD + +FFA QVINNACATQAI+S+LLN DV +G LS KEF+++F + +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 459 LAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPI 638
LA++NS+ IR HNSFAR + F + K + K++D +HF+SY+PV+G LYELDGL+EGPI
Sbjct: 128 LALSNSDVIRQVHNSFARQQMF-EFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPI 186
Query: 639 SLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQR 818
LG C D +W+ V+PVI++RI++YS+ EIRFNL+A++ +RK IY ++ ELQRQ
Sbjct: 187 DLGACNQD----DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQ- 241
Query: 819 EQMVQELAGVEKSRAGELEVLIGEVRSGIEAVSDKIVMEEE--KFMKWKTENIRRKHNYI 992
LA E + ++ ++S E +++++EEE K ++K ENIRRKHNY+
Sbjct: 242 ------LAEEEPMDTDQGNSMLSAIQS--EVAKNQMLIEEEVQKLKRYKIENIRRKHNYL 293
Query: 993 PFLFNFLKLLAEKKQLKPLIEKAKKQKTESST*EKK 1100
PF+ LK LAE +QL PL+EKAK+++ E K
Sbjct: 294 PFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
>sp|Q9WUP7|UCHL5_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Mus
musculus GN=Uchl5 PE=2 SV=2
Length = 329
Score = 314 bits (802), Expect = 1e-084
Identities = 165/336 (49%), Positives = 231/336 (68%), Gaps = 19/336 (5%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDRP 287
WC +ESDPGVFTELI+ +G QVEE++SL+ +S L+PV+GLIFLFKWQ G +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 288 TIQDP-VSNLFFANQVINNACATQAILSILLN--SPDVDIGPELSTLKEFTKNFPSDLKG 458
+QD + +FFA QVINNACATQAI+S+LLN DV +G LS KEF+++F + +KG
Sbjct: 68 VVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 459 LAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPI 638
LA++NS+ IR HNSFAR + F + K K++D +HF+SY+PV+G LYELDGL+EGPI
Sbjct: 128 LALSNSDVIRQVHNSFARQQMF-EFDTKTPAKEEDAFHFVSYVPVNGRLYELDGLREGPI 186
Query: 639 SLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQR 818
LG C D +W+ V+PVI++RI++YS+ EIRFNL+A++ +RK IY ++ ELQRQ
Sbjct: 187 DLGACNQD----DWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQ- 241
Query: 819 EQMVQELAGVEKSRAGELEVLIGEVRSGIEAVSDKIVMEEE--KFMKWKTENIRRKHNYI 992
LA E + ++ ++S E +++++EEE K ++K ENIRRKHNY+
Sbjct: 242 ------LAEEEPMDTDQGSTVLSAIQS--EVARNQMLIEEEVQKLKRYKIENIRRKHNYL 293
Query: 993 PFLFNFLKLLAEKKQLKPLIEKAKKQKTESST*EKK 1100
PF+ LK LAE +QL PL+EKAK+++ E K
Sbjct: 294 PFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
>sp|Q06AT3|UCHL5_PIG Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Sus
scrofa GN=UCHL5 PE=2 SV=1
Length = 329
Score = 313 bits (801), Expect = 2e-084
Identities = 164/336 (48%), Positives = 232/336 (69%), Gaps = 19/336 (5%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDRP 287
WC +ESDPGVFTELI+ +G QVEE++SL+ ++ L+PV+GLIFLFKWQ G +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 288 TIQDP-VSNLFFANQVINNACATQAILSILLN--SPDVDIGPELSTLKEFTKNFPSDLKG 458
+QD + +FFA QVINNACATQAI+S+LLN DV +G LS KEF+++F + +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 459 LAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPI 638
LA++NS+ IR HNSFAR + F + K + K++D +HF+SY+PV+G LYELDGL+EGPI
Sbjct: 128 LALSNSDVIRQVHNSFARQQMF-EFDAKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPI 186
Query: 639 SLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQR 818
LG C D +W+ V+PVI++RI++YS+ EIRFNL+A++ +RK IY ++ ELQRQ
Sbjct: 187 DLGACNQD----DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQ- 241
Query: 819 EQMVQELAGVEKSRAGELEVLIGEVRSGIEAVSDKIVMEEE--KFMKWKTENIRRKHNYI 992
LA E + ++ ++S E +++++EEE K ++K ENIRRKHNY+
Sbjct: 242 ------LAEEEPMDTDQGSNMLSAIQS--EVAKNQMLIEEEVQKLKRYKIENIRRKHNYL 293
Query: 993 PFLFNFLKLLAEKKQLKPLIEKAKKQKTESST*EKK 1100
PF+ LK LAE +QL PL+EKAK+++ E K
Sbjct: 294 PFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
>sp|Q9XSJ0|UCHL5_BOVIN Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Bos
taurus GN=UCHL5 PE=2 SV=1
Length = 328
Score = 261 bits (666), Expect = 8e-069
Identities = 129/239 (53%), Positives = 177/239 (74%), Gaps = 8/239 (3%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDRP 287
WC +ESDPGVFTELI+ +G QVEE++SL+ ++ L+PV+GLIFLFKWQ G +
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGS 67
Query: 288 TIQDP-VSNLFFANQVINNACATQAILSILLN--SPDVDIGPELSTLKEFTKNFPSDLKG 458
+QD + +FFA QVINNACATQAI+S+LLN DV +G LS KEF+++F + +KG
Sbjct: 68 VVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKG 127
Query: 459 LAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPI 638
LA++NS+ IR HNSFAR + F + K A K++D +HF+SY+PV+G LYELDGL+EGPI
Sbjct: 128 LALSNSDVIRQVHNSFARQQMF-EFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLREGPI 186
Query: 639 SLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQ 815
LG C D +W+ V+PVI++RI++YS+ EIRFNL+A++ +RK IY ++ ELQRQ
Sbjct: 187 DLGACNQD----DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQ 241
Score = 66 bits (159), Expect = 5e-010
Identities = 32/67 (47%), Positives = 46/67 (68%), Gaps = 2/67 (2%)
Frame = +3
Query: 906 EAVSDKIVMEEE--KFMKWKTENIRRKHNYIPFLFNFLKLLAEKKQLKPLIEKAKKQKTE 1079
E +++++EEE K ++K ENIRRKHNY+PF+ LK LAE +QL PL+EKAK+++
Sbjct: 262 EVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNA 321
Query: 1080 SST*EKK 1100
E K
Sbjct: 322 KKAQETK 328
>sp|Q9UUB6|UBLH2_SCHPO Ubiquitin carboxyl-terminal hydrolase 2
OS=Schizosaccharomyces pombe GN=uch2 PE=1 SV=1
Length = 300
Score = 242 bits (617), Expect = 4e-063
Identities = 124/227 (54%), Positives = 161/227 (70%), Gaps = 6/227 (2%)
Frame = +3
Query: 102 MSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGV-KD 278
MSW TIESD GVFT+LI+ + VK V+V+ELYSLD+DSL +YG+IFLFKW + V K
Sbjct: 1 MSWTTIESDAGVFTDLIENLGVKDVEVDELYSLDVDSLRQFPDIYGIIFLFKWNSKVDKP 60
Query: 279 DRPTIQDPVSNLFFANQVINNACATQAILSILLN-SPDVDIGPELSTLKEFTKNFPSDLK 455
D D + N+FFA QVINNACATQA+LS+LLN S ++D+G LS K+F+K P +LK
Sbjct: 61 DGTMDYDSMDNIFFAKQVINNACATQALLSVLLNHSDEIDLGTTLSEFKDFSKTLPPELK 120
Query: 456 GLAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGP 635
G A+ NSE IR HNSFAR +PF+ EE +AAT +D+VYHFI+Y ++ V YELDGL+ P
Sbjct: 121 GEALGNSEHIRCCHNSFARSDPFISEEVRAATDEDEVYHFIAYTNINNVFYELDGLQAAP 180
Query: 636 ISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRFNLLAVIKNRK 776
I+ G C T E+ + VIQ RI Y +EIRFNL+ + K++K
Sbjct: 181 INHGSC----TKEEFAEKAVSVIQARIANYDPAEIRFNLMVICKDKK 223
>sp|Q92560|BAP1_HUMAN Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Homo sapiens
GN=BAP1 PE=1 SV=2
Length = 729
Score = 205 bits (521), Expect = 5e-052
Identities = 119/261 (45%), Positives = 161/261 (61%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD I D V+N+FFA+Q+I N+CAT A+LS+LLN VD+GP LS +K+FTK
Sbjct: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWGEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y A L L+ R+ +++ L
Sbjct: 239 IKYEARLHVLKVNRQTVLEAL 259
>sp|D3ZHS6|BAP1_RAT Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Rattus
norvegicus GN=Bap1 PE=3 SV=2
Length = 727
Score = 205 bits (519), Expect = 9e-052
Identities = 118/261 (45%), Positives = 161/261 (61%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDPVSN-LFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD I D + N +FFA+Q+I N+CAT A+LS+LLN +VD+GP LS +K+FTK
Sbjct: 62 VSTLVDDTSVIDDDIVNSMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWGEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y A L L+ R+ +++ L
Sbjct: 239 VKYEARLHVLKGNRQTVLEAL 259
>sp|Q99PU7|BAP1_MOUSE Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Mus musculus
GN=Bap1 PE=1 SV=1
Length = 728
Score = 204 bits (518), Expect = 1e-051
Identities = 118/261 (45%), Positives = 161/261 (61%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD I D V+N+FFA+Q+I N+CAT A+LS+LLN +VD+GP LS +K+FTK
Sbjct: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWGEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y L L+ R+ +++ L
Sbjct: 239 IKYETRLHVLKVNRQTVLEAL 259
>sp|Q66JB6|BAP1_XENTR Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Xenopus
tropicalis GN=bap1 PE=2 SV=1
Length = 685
Score = 202 bits (513), Expect = 5e-051
Identities = 117/261 (44%), Positives = 162/261 (62%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCPG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD ++D V+N+FFA+Q+I N+CAT A+LS+LLN V +GP LS +KEFTK
Sbjct: 62 VSTLLDDTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNCSGVHLGPTLSRIKEFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWAEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y ++L L+ R+ +++ L
Sbjct: 239 LKYESKLHILKMNRQTVLEAL 259
>sp|Q52L14|BAP1_XENLA Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Xenopus
laevis GN=bap1 PE=2 SV=1
Length = 618
Score = 202 bits (512), Expect = 6e-051
Identities = 117/261 (44%), Positives = 161/261 (61%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCPG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD ++D V+N+FFA+Q+I N+CAT A+LS+LLN V +GP LS +KEFTK
Sbjct: 62 VSTLLDDTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNCGGVHLGPTLSRIKEFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWAEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y +L L+ R+ +++ L
Sbjct: 239 LKYEGKLNILKMNRQTVLEAL 259
>sp|Q5F3N6|BAP1_CHICK Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Gallus
gallus GN=BAP1 PE=2 SV=1
Length = 700
Score = 201 bits (510), Expect = 1e-050
Identities = 116/261 (44%), Positives = 162/261 (62%), Gaps = 23/261 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEESRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + D+ I D V+N+FFA+Q+I N+CAT A+LS+LLN +VD+GP LS +K+FTK
Sbjct: 62 VSTLVDETSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCNNVDLGPTLSRMKDFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + A NS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKARNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKVYPIDHGPWADDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQEL 839
Y ++L L+ R+ +++ L
Sbjct: 239 MKYESKLHILKMNRQTVLEAL 259
>sp|A1L2G3|BAP1_DANRE Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Danio rerio
GN=bap1 PE=2 SV=2
Length = 755
Score = 195 bits (495), Expect = 6e-049
Identities = 114/268 (42%), Positives = 163/268 (60%), Gaps = 23/268 (8%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L + PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQS---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDPVSN-LFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + D+ I D + N +FFA+Q+I N+CAT A+LS+LLN V++G LS +K FTK
Sbjct: 62 VSTLVDETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCSGVELGMTLSRMKAFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ L+
Sbjct: 122 FNPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKDRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP D+ EW + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKAYPIDHGPWGEDE---EWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR 238
Query: 777 DIYTAELKELQRQREQMVQELAGVEKSR 860
Y ++L L+R R+ +++ L + + +
Sbjct: 239 IKYESKLDILKRNRQIILEGLQQIREKK 266
>sp|A2VDM8|BAP1_BOVIN Ubiquitin carboxyl-terminal hydrolase BAP1 OS=Bos taurus
GN=BAP1 PE=2 SV=1
Length = 711
Score = 190 bits (481), Expect = 2e-047
Identities = 118/271 (43%), Positives = 161/271 (59%), Gaps = 28/271 (10%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW--------- 260
W +ESDPG+FT L++ VKGVQVEE+Y L PVYG IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQG---PVYGFIFLFKWIEERRSRRK 61
Query: 261 QAGVKDDRPTIQDP-VSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
+ + DD I D V+N+FFA+Q+I N+CAT A+LS+LLN +VD+GP LS +K+FTK
Sbjct: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
F + KG AI N+ + AHNS ARPEP +PE+Q +A + + +HF+SY+P+ G L+
Sbjct: 122 FSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYS---QSEIRFNLLAVIKNRKD 779
ELDGLK PI GP D+ EW + VI ERI + + E R ++L V NR+
Sbjct: 182 ELDGLKVYPIDHGPWGEDE---EWTDKARRVIMERIGLATAGIKYEARLHVLKV--NRQT 236
Query: 780 IYTAELKELQRQREQMVQELAGVEKSRAGEL 872
+ L+ LQ+ EL KS+ +L
Sbjct: 237 V----LEALQQLIRVTQPELIQTHKSQESQL 263
>sp|C4A0D9|BAP1_BRAFL Ubiquitin carboxyl-terminal hydrolase BAP1
OS=Branchiostoma floridae GN=BAP1 PE=3 SV=1
Length = 694
Score = 184 bits (467), Expect = 1e-045
Identities = 111/272 (40%), Positives = 161/272 (59%), Gaps = 26/272 (9%)
Frame = +3
Query: 108 WCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKWQAGVKDDR- 284
W +ESDPG+FT L++ VKGVQVEE+Y L S PVYG IFLFKW + R
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDL---SKPIEGPVYGFIFLFKWSEERRSRRK 61
Query: 285 --PTI-------QDPVSNLFFANQVINNACATQAILSILLNSPDVDIGPELSTLKEFTKN 437
P++ +D V+++FFA Q+I N+CAT A+LS+LLN P + +G L+ LK FT+
Sbjct: 62 VGPSMEESFVVDEDIVNDMFFAQQLIPNSCATHALLSVLLNCPQISLGSTLTRLKYFTRG 121
Query: 438 FPSDLKGLAINNSEAIRTAHNSFARPEP-FVPEEQK--AATKDDDVYHFISYIPVDGVLY 608
+ KG AI N I AHNS ARPEP +PE+Q ++ + + +HF+SY+ + L+
Sbjct: 122 MGPESKGWAIGNVPEIARAHNSHARPEPRHLPEKQTGISSVRTAEAFHFVSYVTTNDRLF 181
Query: 609 ELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSE----IRFNLLAVIKNRK 776
ELDGLK PI GP + +W + + VI ERI + E IRFNL+AV+ +R+
Sbjct: 182 ELDGLKPYPIDHGPWGEKE---DWTEKFRRVISERIGNATGGENGHDIRFNLMAVVADRR 238
Query: 777 DIYTAELKELQRQRE---QMVQELAGVEKSRA 863
Y +L L+ R+ + +Q++ GV ++
Sbjct: 239 QQYETKLNTLKTNRQIVLEALQQVGGVNTKKS 270
>sp|Q17N72|CALYP_AEDAE Ubiquitin carboxyl-terminal hydrolase calypso OS=Aedes
aegypti GN=calypso PE=3 SV=1
Length = 478
Score = 176 bits (445), Expect = 4e-043
Identities = 112/309 (36%), Positives = 168/309 (54%), Gaps = 29/309 (9%)
Frame = +3
Query: 81 LSVARFVMSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW 260
+ + R W +ESDPG+FT L++ VKGVQVEE+Y L N PVYG IFLF+W
Sbjct: 3 VDINRLTDGWLELESDPGLFTLLLEDFGVKGVQVEEIYDL---QKNIEGPVYGFIFLFRW 59
Query: 261 QAGVKDDRPTI---------QDPVSNLFFANQVINNACATQAILSILLNSPDVDIGPELS 413
+ R + ++ V+N+FFA QV+ N+CAT A+LS+LLN D+D+G LS
Sbjct: 60 IEERRARRKIVETTEIYVKDEEAVNNIFFAQQVVPNSCATHALLSVLLNCSDIDLGNTLS 119
Query: 414 TLKEFTKNFPSDLKGLAINNSEAIRTAHNSFARPEPFVPEEQKAATK----DDDVYHFIS 581
LK TK + KG AI N+ + AHNS A P+ ++ + + +HF+S
Sbjct: 120 RLKVHTKGMCPENKGWAIGNTPELACAHNSHAMPQARRRMDRNSGVSTGRFTGEAFHFVS 179
Query: 582 YIPVDGVLYELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIE-RYSQSEIRFNLLA 758
++P++G L+ELDGLK P+ GP + W + V+ +R+ + +IRFNL+A
Sbjct: 180 FVPINGHLFELDGLKPFPMDHGPWGEKEA---WTDKFRRVMSDRLGISTGEQDIRFNLMA 236
Query: 759 VIKNRKDIYTAELKELQRQREQMVQELAGVEKSRAGELEVLIGEVRSGIEAVSDKIVMEE 938
V+ +R+ T +LK L+ + + L + KS+ E +E V DKI EE
Sbjct: 237 VVPDRRIAITHKLKMLRTNQTIVSAALEKLLKSKRTE--------SRSLETV-DKIKKEE 287
Query: 939 EKFMKWKTE 965
E +K +E
Sbjct: 288 ESPVKLSSE 296
>sp|B0W2R4|CALYP_CULQU Ubiquitin carboxyl-terminal hydrolase calypso OS=Culex
quinquefasciatus GN=calypso PE=3 SV=1
Length = 470
Score = 154 bits (388), Expect = 1e-036
Identities = 90/262 (34%), Positives = 145/262 (55%), Gaps = 21/262 (8%)
Frame = +3
Query: 81 LSVARFVMSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDLDSLNNLRPVYGLIFLFKW 260
+ + R W +ESDPG+FT L++ VKGVQVEE+Y L PV+G IFLF+W
Sbjct: 3 VDINRLTDGWLELESDPGLFTLLLEDFGVKGVQVEEIYDLQKTIEG---PVFGFIFLFRW 59
Query: 261 QAGVKDDRPTI----------QDPVSNLFFANQVINNACATQAILSILLNSPDVDIGPEL 410
+ R + ++ V+++FFA+QV+ N+CAT A+LS+LLN D+D+G L
Sbjct: 60 IEERRARRKIVETTTEMYVKDEEAVNSIFFAHQVVPNSCATHALLSVLLNCSDIDLGTTL 119
Query: 411 STLKEFTKNFPSDLKGLAINNSEAIRTAHNSFARPEPFVPEEQKAATK----DDDVYHFI 578
S LK TK D KG AI N+ + AHNS A P+ ++ + + +HF+
Sbjct: 120 SRLKVHTKGMCPDNKGWAIGNTPELACAHNSHAMPQARRRMDRNSGVSTGRFTGEAFHFV 179
Query: 579 SYIPVDGVLYELDGLKEGPISLGPCPGDQTGIEWLQLVQPVIQERIERYSQSEIRF-NLL 755
S+ P++G L+ELDGLK P+ GP + +W + V+ +R+ + I + L
Sbjct: 180 SFCPINGHLFELDGLKPFPMDHGPWGEKE---DWTDKFRRVMSDRLGISTDRRIAITHKL 236
Query: 756 AVIKNRKDIYTAELKELQRQRE 821
+++ + I +A L++L + ++
Sbjct: 237 KMLRTNQTIVSAALEKLLKSKQ 258
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 182,561,833,118
Number of Sequences: 518415
Number of Extensions: 182561833118
Number of Successful Extensions: 1116914633
Number of sequences better than 0.0: 0
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