BLASTX 7.6.2
Query= UN48985 /QuerySize=1240
(1239 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 OS=Sus scr... 216 2e-055
sp|P70406|UCP2_MOUSE Mitochondrial uncoupling protein 2 OS=Mus m... 216 3e-055
sp|P56500|UCP2_RAT Mitochondrial uncoupling protein 2 OS=Rattus ... 216 3e-055
sp|Q3SZI5|UCP2_BOVIN Mitochondrial uncoupling protein 2 OS=Bos t... 215 7e-055
sp|P55851|UCP2_HUMAN Mitochondrial uncoupling protein 2 OS=Homo ... 211 8e-054
sp|Q5R5A8|UCP2_PONAB Mitochondrial uncoupling protein 2 OS=Pongo... 211 8e-054
sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 OS=Mus m... 211 1e-053
sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos t... 211 1e-053
sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 OS=Rattus ... 211 1e-053
sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis... 210 2e-053
sp|Q9N2J1|UCP2_CANFA Mitochondrial uncoupling protein 2 OS=Canis... 210 2e-053
sp|Q9W725|UCP2_CYPCA Mitochondrial uncoupling protein 2 OS=Cypri... 210 2e-053
sp|Q9W720|UCP2_DANRE Mitochondrial uncoupling protein 2 OS=Danio... 207 1e-052
sp|O97649|UCP3_PIG Mitochondrial uncoupling protein 3 OS=Sus scr... 207 2e-052
sp|P55916|UCP3_HUMAN Mitochondrial uncoupling protein 3 OS=Homo ... 198 7e-050
sp|Q9GMZ1|UCP1_CANFA Mitochondrial brown fat uncoupling protein ... 188 7e-047
sp|P25874|UCP1_HUMAN Mitochondrial brown fat uncoupling protein ... 180 2e-044
sp|A0PC02|UCP1_OCHDA Mitochondrial brown fat uncoupling protein ... 180 3e-044
sp|P12242|UCP1_MOUSE Mitochondrial brown fat uncoupling protein ... 178 1e-043
sp|P14271|UCP1_RABIT Mitochondrial brown fat uncoupling protein ... 176 3e-043
>sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 OS=Sus scrofa GN=UCP2
PE=2 SV=1
Length = 309
Score = 216 bits (550), Expect = 2e-055
Identities = 124/266 (46%), Positives = 161/266 (60%), Gaps = 14/266 (5%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ--KSAIAGDVTLPKYRGLLGTVGTIAREEGLR 345
F + AAC+ ++ T PLDTAKVRLQ+Q + +YRG+LGT+ T+ R EG R
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVRNEGPR 76
Query: 346 SLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIMV 522
SL+ G+V GL RQ F +RIG+Y+ VK+ Y G +H G + ++ AG TTGAL + V
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKHFYTKGSEHAG---IGSRLLAGSTTGALAVAV 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA+ + AG RRY +++AY TI R+EG+R LW G PNVARNAI+N
Sbjct: 134 AQPTDVVKVRFQAQAR--AGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNVARNAIVNC 191
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM----GDPS 870
AEL +YD + T+LK TD++ H S GAGF I SPVDVVK+R M G S
Sbjct: 192 AELVTYDLIKDTLLKADLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSAPGQYS 251
Query: 871 LQRHYRLLRQNSEG*RTHGILQGFHP 948
H L EG R +GF P
Sbjct: 252 SAGHCALTMLQKEGPR--AFYKGFTP 275
>sp|P70406|UCP2_MOUSE Mitochondrial uncoupling protein 2 OS=Mus musculus GN=Ucp2
PE=2 SV=1
Length = 309
Score = 216 bits (549), Expect = 3e-055
Identities = 116/240 (48%), Positives = 150/240 (62%), Gaps = 8/240 (3%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ--KSAIAGDVTLPKYRGLLGTVGTIAREEGLR 345
F + AAC+ ++ T PLDTAKVRLQ+Q + +YRG+LGT+ T+ R EG R
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPR 76
Query: 346 SLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIMV 522
SL+ G+V GL RQ F +RIG+Y+ VK Y G +H G + ++ AG TTGAL + V
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAG---IGSRLLAGSTTGALAVAV 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA+ + AG RRY ++ AY TI R+EG+R LW G PNVARNAI+N
Sbjct: 134 AQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNC 191
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDPSLQRH 882
AEL +YD + T+LK TD++ H S GAGF I SPVDVVK+R M Q H
Sbjct: 192 AELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYH 251
>sp|P56500|UCP2_RAT Mitochondrial uncoupling protein 2 OS=Rattus norvegicus
GN=Ucp2 PE=2 SV=1
Length = 309
Score = 216 bits (549), Expect = 3e-055
Identities = 116/240 (48%), Positives = 150/240 (62%), Gaps = 8/240 (3%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ--KSAIAGDVTLPKYRGLLGTVGTIAREEGLR 345
F + AAC+ ++ T PLDTAKVRLQ+Q +A +YRG+LGT+ T+ R EG R
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRTEGPR 76
Query: 346 SLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIMV 522
SL+ G+V GL RQ F +RIG+Y+ VK Y G +H G + ++ AG TTGAL + V
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAG---IGSRLLAGSTTGALAVAV 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA+ + AG RRY ++ AY TI R+EG+R LW G PNVARNAI+N
Sbjct: 134 AQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNC 191
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDPSLQRH 882
EL +YD + T+LK TD++ H S GAGF I SPVDVVK+R M Q H
Sbjct: 192 TELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYH 251
>sp|Q3SZI5|UCP2_BOVIN Mitochondrial uncoupling protein 2 OS=Bos taurus GN=UCP2
PE=2 SV=1
Length = 309
Score = 215 bits (546), Expect = 7e-055
Identities = 123/266 (46%), Positives = 157/266 (59%), Gaps = 14/266 (5%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ--KSAIAGDVTLPKYRGLLGTVGTIAREEGLR 345
F + AAC+ ++ T PLDTAKVRLQ+Q + +YRG+LGT+ T+ R EG R
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGERQGPMQAAASAQYRGVLGTILTMVRTEGPR 76
Query: 346 SLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIMV 522
SL+ G+V GL RQ F +RIG+Y+ VK Y G +H G + ++ AG TTGAL + V
Sbjct: 77 SLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAG---IGSRLLAGSTTGALAVAV 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA+ + AG RRY ++ AY TI R+EG R LW G PNVARNAI+N
Sbjct: 134 AQPTDVVKVRFQAQARAGAG--RRYQSTVEAYKTIAREEGFRGLWKGTSPNVARNAIVNC 191
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM----GDPS 870
AEL +YD + T+LK TD++ H S GAGF I SPVDVVK+R M G S
Sbjct: 192 AELVTYDLIKDTLLKAHLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYS 251
Query: 871 LQRHYRLLRQNSEG*RTHGILQGFHP 948
H L EG +GF P
Sbjct: 252 SAGHCALTMLQKEG--PQAFYKGFMP 275
>sp|P55851|UCP2_HUMAN Mitochondrial uncoupling protein 2 OS=Homo sapiens GN=UCP2
PE=1 SV=1
Length = 309
Score = 211 bits (537), Expect = 8e-054
Identities = 124/267 (46%), Positives = 159/267 (59%), Gaps = 16/267 (5%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDV---TLPKYRGLLGTVGTIAREEGL 342
F + AAC+ ++ T PLDTAKVRLQ+Q + G V +YRG++GT+ T+ R EG
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGES-QGPVRATASAQYRGVMGTILTMVRTEGP 75
Query: 343 RSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIM 519
RSL+ G+V GL RQ F +RIG+Y+ VK Y G +H + ++ AG TTGAL +
Sbjct: 76 RSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAS---IGSRLLAGSTTGALAVA 132
Query: 520 VANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIIN 699
VA PTD+VKV QA+ + AG RRY ++NAY TI R+EG R LW G PNVARNAI+N
Sbjct: 133 VAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVN 190
Query: 700 AAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM----GDP 867
AEL +YD + +LK TD++ H S GAGF I SPVDVVK+R M G
Sbjct: 191 CAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQY 250
Query: 868 SLQRHYRLLRQNSEG*RTHGILQGFHP 948
S H L EG R +GF P
Sbjct: 251 SSAGHCALTMLQKEGPR--AFYKGFMP 275
>sp|Q5R5A8|UCP2_PONAB Mitochondrial uncoupling protein 2 OS=Pongo abelii GN=UCP2
PE=2 SV=1
Length = 309
Score = 211 bits (537), Expect = 8e-054
Identities = 124/267 (46%), Positives = 159/267 (59%), Gaps = 16/267 (5%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDV---TLPKYRGLLGTVGTIAREEGL 342
F + AAC+ ++ T PLDTAKVRLQ+Q + G V +YRG++GT+ T+ R EG
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGES-QGPVHATASAQYRGVMGTILTMVRTEGP 75
Query: 343 RSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIM 519
RSL+ G+V GL RQ F +RIG+Y+ VK Y G +H + ++ AG TTGAL +
Sbjct: 76 RSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAS---IGSRLLAGSTTGALAVA 132
Query: 520 VANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIIN 699
VA PTD+VKV QA+ + AG RRY ++NAY TI R+EG R LW G PNVARNAI+N
Sbjct: 133 VAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVN 190
Query: 700 AAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM----GDP 867
AEL +YD + +LK TD++ H S GAGF I SPVDVVK+R M G
Sbjct: 191 CAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQY 250
Query: 868 SLQRHYRLLRQNSEG*RTHGILQGFHP 948
S H L EG R +GF P
Sbjct: 251 SSAGHCALTMLQKEGPR--AFYKGFMP 275
>sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3
PE=2 SV=1
Length = 308
Score = 211 bits (536), Expect = 1e-053
Identities = 112/234 (47%), Positives = 148/234 (63%), Gaps = 7/234 (2%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSL 351
F + AAC ++ T PLDTAKVRLQ+Q +YRG+LGT+ T+ R EG RS
Sbjct: 17 FLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSV--QYRGVLGTILTMVRTEGPRSP 74
Query: 352 WKGVVPGLHRQCLFGGLRIGMYEPVKNLYV--GKDHVGDVPLSKKIFAGLTTGALGIMVA 525
+ G+V GLHRQ F +RIG+Y+ VK Y G DH ++ +I AG TTGA+ + A
Sbjct: 75 YSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADHSS---VAIRILAGCTTGAMAVTCA 131
Query: 526 NPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAA 705
PTD+VKV QA +L G R+Y G+++AY TI R+EGVR LW G PN+ RNAI+N A
Sbjct: 132 QPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCA 191
Query: 706 ELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
E+ +YD + + +L+ FTDN H +S GAGF A + SPVDVVK+R M P
Sbjct: 192 EMVTYDIIKEKLLESHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAP 245
>sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3
PE=2 SV=1
Length = 311
Score = 211 bits (535), Expect = 1e-053
Identities = 111/240 (46%), Positives = 149/240 (62%), Gaps = 6/240 (2%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ-KSAIAGDVTLPKYRGLLGTVGTIAREEGLRS 348
F + AAC ++ T PLDTAKVRLQ+Q ++ A +YRG+LGT+ T+ R EG RS
Sbjct: 17 FLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRS 76
Query: 349 LWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV--GKDHVGDVPLSKKIFAGLTTGALGIMV 522
L+ G+V GL RQ F +RIG+Y+ VK Y G DH + +I AG TTGA+ +
Sbjct: 77 LYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS---IITRILAGCTTGAMAVTC 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VK+ QA G R+Y+G+++AY TI R+EGVR LW G+ PN+ RNAI+N
Sbjct: 134 AQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNC 193
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDPSLQRH 882
E+ +YD + + +L TDN H +S GAGF A + SPVDVVK+R M P Q H
Sbjct: 194 GEMVTYDIIKEKLLDYHLLTDNFPCHFVSAFGAGFCATLVASPVDVVKTRYMNSPPGQYH 253
>sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 OS=Rattus norvegicus
GN=Ucp3 PE=2 SV=1
Length = 308
Score = 211 bits (535), Expect = 1e-053
Identities = 113/234 (48%), Positives = 148/234 (63%), Gaps = 7/234 (2%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSL 351
F + AAC ++ T PLDTAKVRLQ+Q V +YRG+LGT+ T+ R EG RS
Sbjct: 17 FLGAGTAACFADLLTFPLDTAKVRLQIQGE--NPGVQSVQYRGVLGTILTMVRTEGPRSP 74
Query: 352 WKGVVPGLHRQCLFGGLRIGMYEPVKNLYV--GKDHVGDVPLSKKIFAGLTTGALGIMVA 525
+ G+V GLHRQ F +RIG+Y+ VK Y G DH ++ +I AG TTGA+ + A
Sbjct: 75 YSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSS---VAIRILAGCTTGAMAVTCA 131
Query: 526 NPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAA 705
PTD+VKV QA +L G R+Y G+++AY TI R+EGVR LW G PN+ RNAI+N A
Sbjct: 132 QPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCA 191
Query: 706 ELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
E+ +YD + + +L FTDN H +S GAGF A + SPVDVVK+R M P
Sbjct: 192 EMVTYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAP 245
>sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis familiaris
GN=UCP3 PE=2 SV=1
Length = 311
Score = 210 bits (534), Expect = 2e-053
Identities = 112/235 (47%), Positives = 148/235 (62%), Gaps = 6/235 (2%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLP-KYRGLLGTVGTIAREEGLRS 348
F + AAC ++ T PLDTAKVRLQ+Q A +YRG+LGT+ T+ R EG RS
Sbjct: 17 FLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTEGPRS 76
Query: 349 LWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV--GKDHVGDVPLSKKIFAGLTTGALGIMV 522
+ G+V GL RQ F +RIG+Y+ VK Y G DH ++ +I AG TTGA+ +
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS---ITTRILAGCTTGAMAVSC 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA L AG R+Y+G+++AY TI R+EGVR LW G PN+ RNAI+N
Sbjct: 134 AQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNC 193
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
AE+ +YD + + +L TDN H++S GAGF A + SPVDVVK+R M P
Sbjct: 194 AEMVTYDIIKEKLLDYHLLTDNFPCHLISAFGAGFCATVVASPVDVVKTRYMNSP 248
>sp|Q9N2J1|UCP2_CANFA Mitochondrial uncoupling protein 2 OS=Canis familiaris
GN=UCP2 PE=2 SV=1
Length = 309
Score = 210 bits (533), Expect = 2e-053
Identities = 122/266 (45%), Positives = 157/266 (59%), Gaps = 14/266 (5%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ--KSAIAGDVTLPKYRGLLGTVGTIAREEGLR 345
F + AAC+ ++ T PLDTAKVRLQ+Q + +YRG+L T+ T+ R EG R
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVRTEGPR 76
Query: 346 SLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIMV 522
SL+ G+V GL RQ F +RIG+Y+ VK Y G +H G + ++ AG TTGAL + V
Sbjct: 77 SLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAG---IGSRLLAGSTTGALAVAV 133
Query: 523 ANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINA 702
A PTD+VKV QA+ + AG RRY +++AY TI R+EG R LW G PNVARNAI+N
Sbjct: 134 AQPTDVVKVRFQAQAR--AGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNVARNAIVNC 191
Query: 703 AELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM----GDPS 870
AEL +YD + +LK TD++ H S GAGF I SPVDVVK+R M G S
Sbjct: 192 AELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYS 251
Query: 871 LQRHYRLLRQNSEG*RTHGILQGFHP 948
H L EG R +GF P
Sbjct: 252 SAGHCALTMLQKEGPR--AFYKGFMP 275
>sp|Q9W725|UCP2_CYPCA Mitochondrial uncoupling protein 2 OS=Cyprinus carpio
GN=ucp2 PE=2 SV=1
Length = 310
Score = 210 bits (533), Expect = 2e-053
Identities = 111/238 (46%), Positives = 150/238 (63%), Gaps = 19/238 (7%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLP--------KYRGLLGTVGTIA 327
F + AAC+ ++ T PLDTAKVRLQ+Q G+ +P KYRG+ GT+ T+
Sbjct: 17 FIGAGTAACIADLFTFPLDTAKVRLQIQ-----GESKIPVNTGHGPVKYRGVFGTISTMV 71
Query: 328 REEGLRSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTG 504
R EG RSL+ G+V GL RQ F +RIG+Y+ VK Y G +HVG + ++ AG TTG
Sbjct: 72 RVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHVG---IGSRLMAGCTTG 128
Query: 505 ALGIMVANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVAR 684
A+ + +A PTD+VKV QA+ +AG +RY G+++AY TI ++EG R LW G GPN+ R
Sbjct: 129 AMAVALAQPTDVVKVRFQAQN--SAGANKRYHGTMDAYRTIAKEEGFRGLWKGTGPNITR 186
Query: 685 NAIINAAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM 858
NAI+N EL +YD + +LK TD++ H S GAGF I SPVDVVK+R M
Sbjct: 187 NAIVNCTELVTYDLIKDALLKSSLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYM 244
>sp|Q9W720|UCP2_DANRE Mitochondrial uncoupling protein 2 OS=Danio rerio GN=ucp2
PE=2 SV=1
Length = 310
Score = 207 bits (526), Expect = 1e-052
Identities = 109/233 (46%), Positives = 148/233 (63%), Gaps = 9/233 (3%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ---KSAIAGDVTLPKYRGLLGTVGTIAREEGL 342
F + AAC+ ++ T PLDTAKVRLQ+Q K++ KYRG+ GT+ T+ R EG
Sbjct: 17 FIGAGTAACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTISTMVRVEGP 76
Query: 343 RSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYV-GKDHVGDVPLSKKIFAGLTTGALGIM 519
RSL+ G+V GL RQ F +RIG+Y+ VK Y G DH G + ++ AG TTGA+ +
Sbjct: 77 RSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAG---IGSRLMAGCTTGAMAVA 133
Query: 520 VANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIIN 699
VA PTD++KV QA+ ++AG +RY +++AY TI ++EG R LW G GPN+ RNAI+N
Sbjct: 134 VAQPTDVLKVRFQAQ--VSAGASKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVN 191
Query: 700 AAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM 858
EL +YD + +LK TD++ H S GAGF I SPVDVVK+R M
Sbjct: 192 CTELVTYDLIKDALLKSSLMTDDLPCHFTSAFGAGFCTTIIASPVDVVKTRYM 244
>sp|O97649|UCP3_PIG Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3
PE=2 SV=1
Length = 308
Score = 207 bits (525), Expect = 2e-052
Identities = 109/228 (47%), Positives = 145/228 (63%), Gaps = 7/228 (3%)
Frame = +1
Query: 190 AACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSLWKGVVP 369
AAC ++ T PLDTAKVRLQ+Q A +YRG+LGT+ T+ R EG RS + G+V
Sbjct: 23 AACFADLLTFPLDTAKVRLQIQGENQA--ARSAQYRGVLGTILTMVRNEGPRSPYNGLVA 80
Query: 370 GLHRQCLFGGLRIGMYEPVKNLYV--GKDHVGDVPLSKKIFAGLTTGALGIMVANPTDLV 543
GL RQ F +RIG+Y+ VK LY G DH ++ +I AG TTGA+ + A PTD+V
Sbjct: 81 GLQRQMSFASIRIGLYDSVKQLYTPKGSDHSS---ITTRILAGCTTGAMAVTCAQPTDVV 137
Query: 544 KVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAAELASYD 723
KV QA R+Y+G+++AY TI R+EGVR LW G+ PN+ RNAI+N AE+ +YD
Sbjct: 138 KVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAEMVTYD 197
Query: 724 QVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
+ + +L TDN+ H +S GAGF A + SPVDVVK+R M P
Sbjct: 198 VIKEKVLDYHLLTDNLPCHFVSAFGAGFCATVVASPVDVVKTRYMNSP 245
>sp|P55916|UCP3_HUMAN Mitochondrial uncoupling protein 3 OS=Homo sapiens GN=UCP3
PE=1 SV=1
Length = 312
Score = 198 bits (503), Expect = 7e-050
Identities = 108/234 (46%), Positives = 147/234 (62%), Gaps = 3/234 (1%)
Frame = +1
Query: 172 FACSAFAACVGEVCTIPLDTAKVRLQLQ-KSAIAGDVTLPKYRGLLGTVGTIAREEGLRS 348
F + AAC ++ T PLDTAKVRLQ+Q ++ L +YRG+LGT+ T+ R EG S
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 349 LWKGVVPGLHRQCLFGGLRIGMYEPVKNLYVGKDHVGDVPLSKKIFAGLTTGALGIMVAN 528
+ G+V GL RQ F +RIG+Y+ VK +Y K + L+ +I AG TTGA+ + A
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKG-ADNSSLTTRILAGCTTGAMAVTCAQ 135
Query: 529 PTDLVKVILQAEGKLA-AGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAA 705
PTD+VKV QA L + R+Y+G+++AY TI R+EGVR LW G PN+ RNAI+N A
Sbjct: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
Query: 706 ELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
E+ +YD + + +L TDN H +S GAGF A + SPVDVVK+R M P
Sbjct: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSP 249
>sp|Q9GMZ1|UCP1_CANFA Mitochondrial brown fat uncoupling protein 1 OS=Canis
familiaris GN=UCP1 PE=2 SV=1
Length = 309
Score = 188 bits (477), Expect = 7e-047
Identities = 102/234 (43%), Positives = 139/234 (59%), Gaps = 2/234 (0%)
Frame = +1
Query: 157 SLPKTFACSAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREE 336
+L A +A AAC+ ++ T PLDTAKVRLQ+Q P+YRG+LGTV T+AR E
Sbjct: 12 TLSVRIAAAAGAACLADMITFPLDTAKVRLQIQGEGQGQPPRAPRYRGVLGTVATLARTE 71
Query: 337 GLRSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYVGKDHVGDVPLSKKIFAGLTTGALGI 516
GL+ L+ G+ GL RQ F LRIG+Y+ V+ ++ L +I AG+ TG +
Sbjct: 72 GLQKLYSGLPAGLQRQVGFASLRIGLYDSVRE-WLSPGQGAAASLGSRISAGVMTGGAAV 130
Query: 517 MVANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAII 696
+ PT++VKV LQA+ L P RYTG+ NAY I EG+ LW G PN+ RN II
Sbjct: 131 FIGQPTEVVKVRLQAQSHLHGRKP-RYTGTYNAYRIIATTEGLTGLWKGTTPNLMRNVII 189
Query: 697 NAAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM 858
N EL +YD + + ++K D++ H LS L AGF + SPVDVVK+R +
Sbjct: 190 NCTELVTYDLMKEALVKNHLLADDLPCHFLSALVAGFCTTVLSSPVDVVKTRFV 243
>sp|P25874|UCP1_HUMAN Mitochondrial brown fat uncoupling protein 1 OS=Homo
sapiens GN=UCP1 PE=2 SV=3
Length = 307
Score = 180 bits (456), Expect = 2e-044
Identities = 99/230 (43%), Positives = 137/230 (59%), Gaps = 6/230 (2%)
Frame = +1
Query: 181 SAFAACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSLWKG 360
+ AAC+ +V T PLDTAKVRLQ+Q V +Y+G+LGT+ + + EG L+ G
Sbjct: 20 AGIAACLADVITFPLDTAKVRLQVQGECPTSSVI--RYKGVLGTITAVVKTEGRMKLYSG 77
Query: 361 VVPGLHRQCLFGGLRIGMYEPVKN-LYVGKDHVGDVPLSKKIFAGLTTGALGIMVANPTD 537
+ GL RQ LRIG+Y+ V+ L GK+ L KI AGLTTG + + + PT+
Sbjct: 78 LPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPS--LGSKILAGLTTGGVAVFIGQPTE 135
Query: 538 LVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAAELAS 717
+VKV LQA+ L G+ RYTG+ NAY I EG+ LW G PN+ R+ IIN EL +
Sbjct: 136 VVKVRLQAQSHL-HGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVT 194
Query: 718 YDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDP 867
YD + + +K D++ H++S L AGF A + SPVDVVK+R + P
Sbjct: 195 YDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSP 244
>sp|A0PC02|UCP1_OCHDA Mitochondrial brown fat uncoupling protein 1 OS=Ochotona
daurica GN=UCP1 PE=2 SV=1
Length = 306
Score = 180 bits (455), Expect = 3e-044
Identities = 99/229 (43%), Positives = 138/229 (60%), Gaps = 5/229 (2%)
Frame = +1
Query: 190 AACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSLWKGVVP 369
AAC+ +V T PLDTAKVRLQ+Q + +Y+G+LGT+ T+A+ EG L+ G+
Sbjct: 23 AACLADVITFPLDTAKVRLQIQGE--CQTTSGIRYKGVLGTITTLAKTEGPLKLYSGLPA 80
Query: 370 GLHRQCLFGGLRIGMYEPVKNLYVGKDHVGDVPLSKKIFAGLTTGALGIMVANPTDLVKV 549
GL RQ F LRIG+Y+ V+ + G++ L KI AGLTTG + + + PT++VKV
Sbjct: 81 GLQRQISFASLRIGLYDTVQEFWGGEE--ATPSLRSKICAGLTTGGVAVFIGQPTEVVKV 138
Query: 550 ILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAAELASYDQV 729
LQA+ L G+ RYTG+ NAY I E + LW G PN+ RN IIN EL +YD +
Sbjct: 139 RLQAQSHL-HGLKPRYTGTYNAYRIIATTESLSTLWKGTTPNLLRNIIINCTELVTYDLM 197
Query: 730 NQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGDPSLQ 876
+++ D++ H+LS L AGF + SPVDVVK+R + P Q
Sbjct: 198 KGALVRNDILADDVPCHLLSALIAGFCTTLLSSPVDVVKTRFINSPQGQ 246
>sp|P12242|UCP1_MOUSE Mitochondrial brown fat uncoupling protein 1 OS=Mus
musculus GN=Ucp1 PE=2 SV=2
Length = 307
Score = 178 bits (449), Expect = 1e-043
Identities = 94/223 (42%), Positives = 132/223 (59%), Gaps = 4/223 (1%)
Frame = +1
Query: 190 AACVGEVCTIPLDTAKVRLQLQKSAIAGDVTLPKYRGLLGTVGTIAREEGLRSLWKGVVP 369
+AC+ ++ T PLDTAKVRLQ+Q A +Y+G+LGT+ T+A+ EGL L+ G+
Sbjct: 23 SACLADIITFPLDTAKVRLQIQGEGQASSTI--RYKGVLGTITTLAKTEGLPKLYSGLPA 80
Query: 370 GLHRQCLFGGLRIGMYEPVKNLYVGKDHVGDVPLSKKIFAGLTTGALGIMVANPTDLVKV 549
G+ RQ F LRIG+Y+ V+ Y L KI AGL TG + + + PT++VKV
Sbjct: 81 GIQRQISFASLRIGLYDSVQE-YFSSGRETPASLGNKISAGLMTGGVAVFIGQPTEVVKV 139
Query: 550 ILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVARNAIINAAELASYDQV 729
+QA+ L G+ RYTG+ NAY I E + LW G PN+ RN IIN EL +YD +
Sbjct: 140 RMQAQSHL-HGIKPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYDLM 198
Query: 730 NQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMM 858
++ D++ H+LS L AGF + SPVDVVK+R +
Sbjct: 199 KGALVNNKILADDVPCHLLSALVAGFCTTLLASPVDVVKTRFI 241
>sp|P14271|UCP1_RABIT Mitochondrial brown fat uncoupling protein 1
OS=Oryctolagus cuniculus GN=UCP1 PE=2 SV=1
Length = 306
Score = 176 bits (446), Expect = 3e-043
Identities = 99/241 (41%), Positives = 140/241 (58%), Gaps = 11/241 (4%)
Frame = +1
Query: 160 LPKTFACSAF----AACVGEVCTIPLDTAKVRLQLQ-KSAIAGDVTLPKYRGLLGTVGTI 324
+P T F AAC+ +V T PLDTAKVR Q+Q + I + +Y+G+LGT+ T+
Sbjct: 9 VPPTMGVKIFSAGVAACLADVITFPLDTAKVRQQIQGEFPITSGI---RYKGVLGTITTL 65
Query: 325 AREEGLRSLWKGVVPGLHRQCLFGGLRIGMYEPVKNLYVGKDHVGDVPLSKKIFAGLTTG 504
A+ EG L+ G+ GL RQ F LRIG+Y+ V+ + + L KI AGLTTG
Sbjct: 66 AKTEGPLKLYSGLPAGLQRQISFASLRIGLYDTVQEFFTSGEETPS--LGSKISAGLTTG 123
Query: 505 ALGIMVANPTDLVKVILQAEGKLAAGVPRRYTGSLNAYSTIVRQEGVRALWTGLGPNVAR 684
+ + + PT++VKV LQA+ L G+ RYTG+ NAY I E + +LW G PN+ R
Sbjct: 124 GVAVFIGQPTEVVKVRLQAQSHL-HGLKPRYTGTYNAYRIIATTESLTSLWKGTTPNLLR 182
Query: 685 NAIINAAELASYDQVNQTILKIPGFTDNIVTHILSGLGAGFFAVCIGSPVDVVKSRMMGD 864
N IIN EL +YD + +++ D++ H +S L AGF + SPVDVVK+R +
Sbjct: 183 NVIINCTELVTYDLMKGALVRNEILADDVPCHFVSALIAGFCTTLLSSPVDVVKTRFINS 242
Query: 865 P 867
P
Sbjct: 243 P 243
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 182,561,833,118
Number of Sequences: 518415
Number of Extensions: 182561833118
Number of Successful Extensions: 1116914633
Number of sequences better than 0.0: 0
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