BLASTX 7.6.2
Query= UN49003 /QuerySize=976
(975 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q1XDM0|ODPA_PORYE Pyruvate dehydrogenase E1 component subunit... 330 1e-089
sp|P51267|ODPA_PORPU Pyruvate dehydrogenase E1 component subunit... 325 5e-088
sp|Q1RJX4|ODPA_RICBR Pyruvate dehydrogenase E1 component subunit... 217 1e-055
sp|Q4UKQ6|ODPA_RICFE Pyruvate dehydrogenase E1 component subunit... 216 2e-055
sp|Q92IS3|ODPA_RICCN Pyruvate dehydrogenase E1 component subunit... 214 9e-055
sp|Q9R9N5|ODPA_RHIME Pyruvate dehydrogenase E1 component subunit... 214 1e-054
sp|Q68XA9|ODPA_RICTY Pyruvate dehydrogenase E1 component subunit... 210 2e-053
sp|Q9ZDR4|ODPA_RICPR Pyruvate dehydrogenase E1 component subunit... 208 8e-053
sp|O66112|ODPA_ZYMMO Pyruvate dehydrogenase E1 component subunit... 199 4e-050
sp|Q5HGZ1|ODPA_STAAC Pyruvate dehydrogenase E1 component subunit... 140 2e-032
sp|P60089|ODPA_STAAM Pyruvate dehydrogenase E1 component subunit... 140 2e-032
sp|Q820A6|ODPA_STAAN Pyruvate dehydrogenase E1 component subunit... 140 2e-032
sp|Q6GAC1|ODPA_STAAS Pyruvate dehydrogenase E1 component subunit... 140 2e-032
sp|P60090|ODPA_STAAW Pyruvate dehydrogenase E1 component subunit... 140 2e-032
sp|Q72GU1|ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alph... 138 6e-032
sp|Q5SLR4|ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alph... 138 6e-032
sp|Q6GHZ2|ODPA_STAAR Pyruvate dehydrogenase E1 component subunit... 138 6e-032
sp|Q5HQ76|ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit... 130 2e-029
sp|Q8CPN3|ODPA_STAES Pyruvate dehydrogenase E1 component subunit... 130 2e-029
sp|P37940|ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alph... 128 8e-029
>sp|Q1XDM0|ODPA_PORYE Pyruvate dehydrogenase E1 component subunit alpha
OS=Porphyra yezoensis GN=pdhA PE=3 SV=1
Length = 346
Score = 330 bits (845), Expect = 1e-089
Identities = 164/248 (66%), Positives = 198/248 (79%), Gaps = 3/248 (1%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
VM+ELFGK TGC +G+GGSMH+FS HN LGGFAFI EGIPVATGAAF S Y+++VLK+
Sbjct: 99 VMAELFGKETGCSKGRGGSMHIFSAPHNFLGGFAFIAEGIPVATGAAFQSIYRQQVLKE- 157
Query: 182 CED--VTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIW 355
ED VT FFGDGT NNGQF+ECLNMA L+KLPIIFVVENN WAIGM+H RS+S PEI
Sbjct: 158 TEDLRVTACFFGDGTTNNGQFFECLNMAVLWKLPIIFVVENNQWAIGMAHHRSSSIPEIH 217
Query: 356 KKGPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELR 535
KK AFG+PG+ VDGMDVL VR+ AK+AV RAR+G+GPTL+E TYRFRGHSLADPDELR
Sbjct: 218 KKAEAFGLPGIEVDGMDVLAVRQAAKQAVQRARQGDGPTLIEALTYRFRGHSLADPDELR 277
Query: 536 DAAEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQ 715
EK + ARDPI LKKY+++N++AN GEL I+ + +E+AV+FA +SP+P S+
Sbjct: 278 SRQEKEAWVARDPIKKLKKYILDNEIANIGELNEIQNAVKTELEQAVKFAISSPEPNMSE 337
Query: 716 LLENVFAD 739
L +FAD
Sbjct: 338 LKRYLFAD 345
>sp|P51267|ODPA_PORPU Pyruvate dehydrogenase E1 component subunit alpha
OS=Porphyra purpurea GN=pdhA PE=3 SV=1
Length = 344
Score = 325 bits (831), Expect = 5e-088
Identities = 161/247 (65%), Positives = 197/247 (79%), Gaps = 1/247 (0%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
VM+ELFGK TGC RG+GGSMH+FS HN LGGFAFI EGIPVATGAAF S Y+++VLK+
Sbjct: 97 VMAELFGKETGCSRGRGGSMHIFSAPHNFLGGFAFIAEGIPVATGAAFQSIYRQQVLKEP 156
Query: 182 CE-DVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWK 358
E VT FFGDGT NNGQF+ECLNMA L+KLPIIFVVENN WAIGM+H RS+S PEI K
Sbjct: 157 GELRVTACFFGDGTTNNGQFFECLNMAVLWKLPIIFVVENNQWAIGMAHHRSSSIPEIHK 216
Query: 359 KGPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRD 538
K AFG+PG+ VDGMDVL VR+VA++AV RAR+G+GPTL+E TYRFRGHSLADPDELR
Sbjct: 217 KAEAFGLPGIEVDGMDVLAVRQVAEKAVERARQGQGPTLIEALTYRFRGHSLADPDELRS 276
Query: 539 AAEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQL 718
EK + ARDPI LKK++++N++A+ EL I+ + +E++VEFA +SP+P S+L
Sbjct: 277 RQEKEAWVARDPIKKLKKHILDNQIASSDELNDIQSSVKIDLEQSVEFAMSSPEPNISEL 336
Query: 719 LENVFAD 739
+FAD
Sbjct: 337 KRYLFAD 343
>sp|Q1RJX4|ODPA_RICBR Pyruvate dehydrogenase E1 component subunit alpha
OS=Rickettsia bellii (strain RML369-C) GN=pdhA PE=3 SV=1
Length = 326
Score = 217 bits (552), Expect = 1e-055
Identities = 100/244 (40%), Positives = 154/244 (63%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
V++EL G+ TGC +G+GGSMH+F + GG +G +P+ TG AF KY G
Sbjct: 88 VLAELMGRATGCSKGKGGSMHLFDVPNKFYGGHGIVGAQVPIGTGLAFAEKY------NG 141
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++ F GDG N GQ YE NMAAL+ LP+++++ENN +++G S RST +++KK
Sbjct: 142 TNNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVARSTFMRDLYKK 201
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+ G ++GMD ++ + K+A R P ++E +TYR+RGHS++DP + R
Sbjct: 202 GESFGIKGFQLNGMDFEEMYDGVKQAAEYVRENSMPLILEVKTYRYRGHSMSDPAKYRSK 261
Query: 542 AEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLL 721
E Y RDPIT ++K ++EN A+E +LK IE+ + E+V+EAVEF++ SP P +L
Sbjct: 262 EEVETYKERDPITEIRKIILENNYASEADLKEIEQSVKEIVKEAVEFSENSPLPNEEELY 321
Query: 722 ENVF 733
++
Sbjct: 322 TQIY 325
>sp|Q4UKQ6|ODPA_RICFE Pyruvate dehydrogenase E1 component subunit alpha
OS=Rickettsia felis GN=pdhA PE=3 SV=1
Length = 326
Score = 216 bits (549), Expect = 2e-055
Identities = 100/244 (40%), Positives = 154/244 (63%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
V++EL G+ TGC +G+GGSMH+F + GG +G +P+ TG AF KY G
Sbjct: 88 VLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGTGLAFAEKY------NG 141
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++ F GDG N GQ YE NMAAL+ LP+++++ENN +++G S RST +++KK
Sbjct: 142 TNNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVARSTFMRDLYKK 201
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+ G +DGMD ++ AK+A R P ++E +TYR+RGHS++DP + R
Sbjct: 202 GESFGIKGFQLDGMDFEEMYNGAKQAAEYVRENSFPLILEVKTYRYRGHSMSDPAKYRSK 261
Query: 542 AEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLL 721
E +Y RDP+ ++K +++NK A E +LK IE+ + E+V+EAV+F++ SP P +L
Sbjct: 262 EEVEQYKERDPLVIIRKTILDNKYATEADLKEIEQSVKEIVKEAVKFSENSPLPDEGELY 321
Query: 722 ENVF 733
V+
Sbjct: 322 TEVY 325
>sp|Q92IS3|ODPA_RICCN Pyruvate dehydrogenase E1 component subunit alpha
OS=Rickettsia conorii GN=pdhA PE=3 SV=1
Length = 326
Score = 214 bits (544), Expect = 9e-055
Identities = 98/244 (40%), Positives = 155/244 (63%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
V++EL G+ TGC +G+GGSMH+F+ + GG +G +P+ TG AF KY
Sbjct: 88 VLAELMGRATGCSKGKGGSMHLFNVPNKFYGGHGIVGAQVPIGTGLAFVEKY------ND 141
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++ F GDG N GQ YE NMAAL+ LP+++++ENN +++G S RST +++KK
Sbjct: 142 THNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVARSTFMRDLYKK 201
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+ G +DGMD ++ + +K+A R P ++E +TYR+RGHS++DP + R
Sbjct: 202 GASFGIKGFQLDGMDFEEMYDGSKQAAEYVRENSFPLILEVKTYRYRGHSMSDPAKYRSK 261
Query: 542 AEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLL 721
E +Y RDP+ ++K +++NK E +LK+IE+ + E+V+EAVEF++ SP P +L
Sbjct: 262 EEVEQYKERDPLVIIRKTILDNKYVTEADLKAIEQSVKEIVKEAVEFSENSPLPDEGELY 321
Query: 722 ENVF 733
V+
Sbjct: 322 TQVY 325
>sp|Q9R9N5|ODPA_RHIME Pyruvate dehydrogenase E1 component subunit alpha
OS=Rhizobium meliloti GN=pdhA PE=3 SV=1
Length = 348
Score = 214 bits (543), Expect = 1e-054
Identities = 106/244 (43%), Positives = 160/244 (65%), Gaps = 7/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
VM+EL G+ G +G+GGSMHMFSKE + GG +G + + TG AF ++Y+ G
Sbjct: 109 VMAELTGRRGGLSKGKGGSMHMFSKEKHFYGGHGIVGAQVSLGTGLAFANRYR------G 162
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++V++A+FGDG N GQ YE NMAAL+KLP+I++VENN +A+G S R+++ + ++
Sbjct: 163 NDNVSLAYFGDGAANQGQVYESFNMAALWKLPVIYIVENNRYAMGTSVSRASAQTDFSQR 222
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+PG VDGMDV V+ A EAV R G+GP ++E TYR+RGHS++DP + R
Sbjct: 223 GASFGIPGYQVDGMDVRAVKAAADEAVEHCRSGKGPIILEMLTYRYRGHSMSDPAKYRSK 282
Query: 542 AEKAKY-AARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQL 718
E K + DPI +K L + A E ELK I+K++ ++V ++ +FA + P+P S+L
Sbjct: 283 DEVQKMRSEHDPIEQVKARLTDKGWATEDELKQIDKEVRDIVADSADFAQSDPEPDVSEL 342
Query: 719 LENV 730
++
Sbjct: 343 YTDI 346
>sp|Q68XA9|ODPA_RICTY Pyruvate dehydrogenase E1 component subunit alpha
OS=Rickettsia typhi GN=pdhA PE=3 SV=1
Length = 326
Score = 210 bits (532), Expect = 2e-053
Identities = 95/244 (38%), Positives = 153/244 (62%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
V++EL G+ TGC +G+GGSMH+F + GG +G +P+ TG AF KY G
Sbjct: 88 VLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGTGLAFAEKY------NG 141
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++ F GDG N GQ YE NMA+L+ LP+++++ENN +++G S RST +++KK
Sbjct: 142 TNNICFTFLGDGAVNQGQVYEAFNMASLWGLPVVYIIENNEYSMGTSVSRSTFMRDLYKK 201
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+ G +DGMD ++ K+ R P ++E +TYR+RGHS++DP + R
Sbjct: 202 GESFGIRGFQLDGMDFEEMYNGTKQVAEYVRENSFPVILEVKTYRYRGHSMSDPAKYRSK 261
Query: 542 AEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLL 721
E AKY RD + +++ +++NK A E +LK+IE+ + E+++ AVEF++ SP P +L
Sbjct: 262 EEVAKYKERDTLVRIRQIILDNKYATEEDLKAIERSVQEVIKVAVEFSENSPLPSEDELY 321
Query: 722 ENVF 733
+++
Sbjct: 322 TDIY 325
>sp|Q9ZDR4|ODPA_RICPR Pyruvate dehydrogenase E1 component subunit alpha
OS=Rickettsia prowazekii GN=pdhA PE=3 SV=1
Length = 326
Score = 208 bits (527), Expect = 8e-053
Identities = 95/244 (38%), Positives = 151/244 (61%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
V++EL G+ TGC +G+GGSMH+F + GG +G +P+ TG AF KY G
Sbjct: 88 VLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGTGLAFAEKY------NG 141
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
++ F GDG N GQ YE NMA+L+ LPI++++ENN +++G S RST +++KK
Sbjct: 142 TNNICFTFLGDGAVNQGQVYEAFNMASLWGLPIVYIIENNEYSMGTSVARSTFMCDLYKK 201
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G +FG+ G +DGMD ++ K+ R P ++E +TYR+RGHS++DP + R
Sbjct: 202 GESFGIRGFQLDGMDFEEMYNGTKQVAEYVRENSFPVILEVKTYRYRGHSMSDPAKYRSK 261
Query: 542 AEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLL 721
E KY RD + +++ +++NK A E +LK+IE+ + E+++ AVEF++ SP P +L
Sbjct: 262 EEVEKYKERDTLVRIREIILDNKYATEADLKAIEQSVREIIKVAVEFSENSPLPAEDELY 321
Query: 722 ENVF 733
++
Sbjct: 322 TEIY 325
>sp|O66112|ODPA_ZYMMO Pyruvate dehydrogenase E1 component subunit alpha
OS=Zymomonas mobilis GN=pdhA PE=3 SV=1
Length = 354
Score = 199 bits (504), Expect = 4e-050
Identities = 106/244 (43%), Positives = 151/244 (61%), Gaps = 8/244 (3%)
Frame = +2
Query: 2 VMSELFGKVTGCCRGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQG 181
VM+EL G+ +G G+GGSMHMFS EH GG +G +P+ G AF KY+ + G
Sbjct: 113 VMAELTGRASGISHGKGGSMHMFSTEHKFFGGNGIVGAQVPLGAGLAFAHKYRND---GG 169
Query: 182 CEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKK 361
C + A+FGDG+ N GQ YE NMAAL+KLP+IFV+ENN +A+G S R+ + + ++
Sbjct: 170 C---SAAYFGDGSANQGQVYEAYNMAALWKLPVIFVIENNGYAMGTSIQRANAHTALSER 226
Query: 362 GPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDELRDA 541
G FG+P + VDGMDVL+VR A AV + G+GP ++E +TYR+RGHS++DP R
Sbjct: 227 GAGFGIPALVVDGMDVLEVRGAATVAVDWVQAGKGPIILEMKTYRYRGHSMSDPARYRSR 286
Query: 542 AE-KAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQL 718
E DP+ LKK L + E EL +++ I + V+EA +FA+ +P P +L
Sbjct: 287 EEVNDMKENHDPLDNLKKDLFAAGVP-EAELVKLDEDIRQQVKEAADFAEKAPLPADEEL 345
Query: 719 LENV 730
N+
Sbjct: 346 YTNI 349
>sp|Q5HGZ1|ODPA_STAAC Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain COL) GN=pdhA PE=3 SV=1
Length = 370
Score = 140 bits (351), Expect = 2e-032
Identities = 81/228 (35%), Positives = 123/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG A G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQAAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|P60089|ODPA_STAAM Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=pdhA PE=1 SV=1
Length = 370
Score = 140 bits (351), Expect = 2e-032
Identities = 81/228 (35%), Positives = 123/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG A G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQAAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|Q820A6|ODPA_STAAN Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain N315) GN=pdhA PE=1 SV=1
Length = 370
Score = 140 bits (351), Expect = 2e-032
Identities = 81/228 (35%), Positives = 123/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG A G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQAAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|Q6GAC1|ODPA_STAAS Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MSSA476) GN=pdhA PE=3 SV=1
Length = 370
Score = 140 bits (351), Expect = 2e-032
Identities = 81/228 (35%), Positives = 123/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG A G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQAAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|P60090|ODPA_STAAW Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MW2) GN=pdhA PE=3 SV=1
Length = 370
Score = 140 bits (351), Expect = 2e-032
Identities = 81/228 (35%), Positives = 123/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG A G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQAAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|Q72GU1|ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alpha OS=Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) GN=TT_C1757 PE=3
SV=1
Length = 367
Score = 138 bits (347), Expect = 6e-032
Identities = 94/250 (37%), Positives = 131/250 (52%), Gaps = 11/250 (4%)
Frame = +2
Query: 5 MSELFGKV--TGCCRGQGGSM--HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVL 172
+ ELFG++ T +G M H SK N + I +P A GAA + K +L
Sbjct: 108 LKELFGQMLATKADPNKGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAISMK----LL 163
Query: 173 KQGCEDVTVAFFGDGTCNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEI 352
+ G V V FGDG + G +Y +N AA+ P +FV ENN +AI + + T P I
Sbjct: 164 RTG--QVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFVCENNFYAISVDYRHQTHSPTI 221
Query: 353 WKKGPAFGMPGVHVDGMDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPD-E 529
K AFG+PG VDGMDVL V KEAV RARRGEGP+LVE YR+ HS AD D
Sbjct: 222 ADKAHAFGIPGYLVDGMDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADDDSR 281
Query: 530 LRDAAEKAKYAARDPITALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGR 709
R E A + +DPI +++L L NE + + ++I +E ++ A+ +
Sbjct: 282 YRPKEEVAFWRKKDPIPRFRRFLEARGLWNEEWEEDVREEIRAELERGLKEAEEAGPVPP 341
Query: 710 SQLLENVFAD 739
+ +VFA+
Sbjct: 342 EWMFADVFAE 351
>sp|Q5SLR4|ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alpha OS=Thermus
thermophilus (strain HB8 / ATCC 27634 / DSM 579) GN=TTHA0229 PE=1 SV=1
Length = 367
Score = 138 bits (347), Expect = 6e-032
Identities = 88/234 (37%), Positives = 124/234 (52%), Gaps = 7/234 (2%)
Frame = +2
Query: 41 RGQGGSMHMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGT 220
+G+ H SK N + I +P A GAA + K +L+ G V V FGDG
Sbjct: 124 KGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAISMK----LLRTG--QVAVCTFGDGA 177
Query: 221 CNNGQFYECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDG 400
+ G +Y +N AA+ P +F+ ENN +AI + + T P I K AFG+PG VDG
Sbjct: 178 TSEGDWYAGINFAAVQGAPAVFIAENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDG 237
Query: 401 MDVLKVREVAKEAVGRARRGEGPTLVECETYRFRGHSLADPD-ELRDAAEKAKYAARDPI 577
MDVL V KEAV RARRGEGP+LVE YR+ HS AD D R E A + +DPI
Sbjct: 238 MDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRKKDPI 297
Query: 578 TALKKYLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
+++L L NE + + ++I +E ++ A+ + + E+VFA+
Sbjct: 298 PRFRRFLEARGLWNEEWEEDVREEIRAELERGLKEAEEAGPVPPEWMFEDVFAE 351
>sp|Q6GHZ2|ODPA_STAAR Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MRSA252) GN=pdhA PE=3 SV=1
Length = 370
Score = 138 bits (347), Expect = 6e-032
Identities = 80/228 (35%), Positives = 122/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQTAGVAFALK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N AA YK P IFV++NN +AI + T+ + +K A G+PG+ VDGMD L V
Sbjct: 185 EGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ KEA RA GEGPTL+E TYR+ H++A DP R + E A++ +DP+ +K+
Sbjct: 245 QATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKF 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L+E ++ D
Sbjct: 305 LENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYED 352
>sp|Q5HQ76|ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=pdhA PE=3
SV=1
Length = 370
Score = 130 bits (326), Expect = 2e-029
Identities = 75/228 (32%), Positives = 121/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQTAGVAFGLK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N A+ YK P IFV++NN +AI + T+ + +K + G+PG+ VDGMD L V
Sbjct: 185 EGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ EA RA GEGPT++E TYR+ H++A DP R + E A++ +DP+ +KY
Sbjct: 245 QATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKY 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L++ ++ +
Sbjct: 305 LEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEE 352
>sp|Q8CPN3|ODPA_STAES Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus epidermidis (strain ATCC 12228) GN=pdhA PE=3 SV=1
Length = 370
Score = 130 bits (326), Expect = 2e-029
Identities = 75/228 (32%), Positives = 121/228 (53%), Gaps = 8/228 (3%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
+ F + N L IG G AF K K+G V + + GDG + G FY
Sbjct: 131 NQFPEGVNALSPQIIIGAQYIQTAGVAFGLK------KRGKNAVAITYTGDGGSSQGDFY 184
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E +N A+ YK P IFV++NN +AI + T+ + +K + G+PG+ VDGMD L V
Sbjct: 185 EGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAVY 244
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLA--DPDELRDAAEKAKYAARDPITALKKY 595
+ EA RA GEGPT++E TYR+ H++A DP R + E A++ +DP+ +KY
Sbjct: 245 QATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKY 304
Query: 596 LVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFAD 739
L L NE + + ++ ++ A++ AD + + + L++ ++ +
Sbjct: 305 LEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEE 352
>sp|P37940|ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alpha OS=Bacillus
subtilis GN=bfmBAA PE=1 SV=1
Length = 330
Score = 128 bits (320), Expect = 8e-029
Identities = 77/228 (33%), Positives = 125/228 (54%), Gaps = 11/228 (4%)
Frame = +2
Query: 62 HMFSKEHNVLGGFAFIGEGIPVATGAAFTSKYKREVLKQGCEDVTVAFFGDGTCNNGQFY 241
H K++ ++ G + + +P A G A + +++ + FG+G+ N G F+
Sbjct: 110 HFGQKKNRIVTGSSPVTTQVPHAVGIALAGRMEKK------DIAAFVTFGEGSSNQGDFH 163
Query: 242 ECLNMAALYKLPIIFVVENNLWAIGMSHLRSTSDPEIWKKGPAFGMPGVHVDGMDVLKVR 421
E N AA++KLP+IF+ ENN +AI + + + + I + +GMPGV V+G D L+V
Sbjct: 164 EGANFAAVHKLPVIFMCENNKYAISVPYDKQVACENISDRAIGYGMPGVTVNGNDPLEVY 223
Query: 422 EVAKEAVGRARRGEGPTLVECETYRFRGHSLADPDEL---RDAAEKAKYAARDPITALKK 592
+ KEA RARRGEGPTL+E +YR HS D D R+ E+AK + DP+ +
Sbjct: 224 QAVKEARERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEEAKKS--DPLLTYQA 281
Query: 593 YLVENKLANEGELKSIEKKIDELVEEAVEFADASPQPGRSQLLENVFA 736
YL E L ++ +++ +I +V EA + A+ +P L+ V+A
Sbjct: 282 YLKETGLLSDEIEQTMLDEIMAIVNEATDEAENAPYAAPESALDYVYA 329
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 182,561,833,118
Number of Sequences: 518415
Number of Extensions: 182561833118
Number of Successful Extensions: 1116914633
Number of sequences better than 0.0: 0
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