BLASTX 7.6.2
Query= UN49133 /QuerySize=1327
(1326 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P44960|MENB_HAEIN Naphthoate synthase OS=Haemophilus influenz... 371 6e-102
sp|Q9CLV5|MENB_PASMU Naphthoate synthase OS=Pasteurella multocid... 371 6e-102
sp|P0ABU1|MENB_ECOL6 Naphthoate synthase OS=Escherichia coli O6 ... 367 1e-100
sp|P0ABU0|MENB_ECOLI Naphthoate synthase OS=Escherichia coli (st... 367 1e-100
sp|P23966|MENB_BACSU Naphthoate synthase OS=Bacillus subtilis GN... 349 3e-095
sp|Q5HQC3|MENB_STAEQ Naphthoate synthase OS=Staphylococcus epide... 346 3e-094
sp|Q8CPQ4|MENB_STAES Naphthoate synthase OS=Staphylococcus epide... 346 3e-094
sp|Q4L549|MENB_STAHJ Naphthoate synthase OS=Staphylococcus haemo... 343 2e-093
sp|Q6GAG7|MENB_STAAS Naphthoate synthase OS=Staphylococcus aureu... 342 5e-093
sp|Q8NXA0|MENB_STAAW Naphthoate synthase OS=Staphylococcus aureu... 342 5e-093
sp|Q5HH38|MENB_STAAC Naphthoate synthase OS=Staphylococcus aureu... 341 7e-093
sp|Q6GI37|MENB_STAAR Naphthoate synthase OS=Staphylococcus aureu... 341 7e-093
sp|Q99V48|MENB_STAAM Naphthoate synthase OS=Staphylococcus aureu... 340 2e-092
sp|Q7A6A9|MENB_STAAN Naphthoate synthase OS=Staphylococcus aureu... 340 2e-092
sp|Q49WG8|MENB_STAS1 Naphthoate synthase OS=Staphylococcus sapro... 340 2e-092
sp|Q9TM10|MENB_CYACA Naphthoate synthase OS=Cyanidium caldarium ... 305 7e-082
sp|P64017|ECHA8_MYCBO Probable enoyl-CoA hydratase echA8 OS=Myco... 126 4e-028
sp|P64016|ECHA8_MYCTU Probable enoyl-CoA hydratase echA8 OS=Myco... 126 4e-028
sp|P52046|CRT_CLOAB 3-hydroxybutyryl-CoA dehydratase OS=Clostrid... 124 2e-027
sp|O07137|ECHA8_MYCLE Probable enoyl-CoA hydratase echA8 OS=Myco... 119 4e-026
>sp|P44960|MENB_HAEIN Naphthoate synthase OS=Haemophilus influenzae GN=menB PE=3
SV=1
Length = 285
Score = 371 bits (952), Expect = 6e-102
Identities = 187/265 (70%), Positives = 215/265 (81%), Gaps = 2/265 (0%)
Frame = +1
Query: 385 FVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTK 564
+ DI Y K+ + IAKITINRPE RNAFRPQTVKE+M AF+DAR D ++GVI+LTG+G K
Sbjct: 22 YSDIRYHKST-DGIAKITINRPEVRNAFRPQTVKEMMTAFSDARFDENIGVIVLTGEGEK 80
Query: 565 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 741
AFCSGGDQ +R GY D + V LNVLD Q IR PKPV+AMVAGYA+GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRDIRSCPKPVVAMVAGYAIGGGHVLHML 140
Query: 742 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 921
CDLTIAA+NAIFGQTGPKVGSFD G+G+S M+RLVG KKARE+WF+ R Y A EA MGL
Sbjct: 141 CDLTIAAENAIFGQTGPKVGSFDGGWGASYMARLVGQKKAREIWFLCRQYNAQEALDMGL 200
Query: 922 INTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1101
+NTVVP DLEKETV+WCRE+LRNSP AIR LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPYADLEKETVRWCREMLRNSPIAIRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1102 EEGIEGRTAYMQRRPPDFSKFPRRP 1176
EEG EGR A+ ++R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNEKRAPDFSKFRRNP 285
>sp|Q9CLV5|MENB_PASMU Naphthoate synthase OS=Pasteurella multocida GN=menB PE=3
SV=1
Length = 285
Score = 371 bits (952), Expect = 6e-102
Identities = 184/265 (69%), Positives = 216/265 (81%), Gaps = 2/265 (0%)
Frame = +1
Query: 385 FVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTK 564
+ DI+Y K+ + IAKITINRPE RNAFRPQTVKE+++AF DAR D +GVI+LTG+G K
Sbjct: 22 YTDILYHKSL-DGIAKITINRPEVRNAFRPQTVKEMIQAFADARFDEQIGVIVLTGQGEK 80
Query: 565 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 741
AFCSGGDQ +R GY D + V LNVLD Q IR PKPV+AMVAGYA+GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYQDESGVHHLNVLDFQRDIRTCPKPVVAMVAGYAIGGGHVLHMI 140
Query: 742 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 921
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A EA +MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKEALEMGL 200
Query: 922 INTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1101
+NTVVP +LEKETV+WCRE+LRNSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPYAELEKETVRWCREMLRNSPIALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1102 EEGIEGRTAYMQRRPPDFSKFPRRP 1176
EEG EGR A+ ++R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNEKRAPDFSKFKRNP 285
>sp|P0ABU1|MENB_ECOL6 Naphthoate synthase OS=Escherichia coli O6 GN=menB PE=3
SV=1
Length = 285
Score = 367 bits (941), Expect = 1e-100
Identities = 185/265 (69%), Positives = 215/265 (81%), Gaps = 2/265 (0%)
Frame = +1
Query: 385 FVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTK 564
F DI YEK+ + IAKITINRP+ RNAFRP TVKE+++A DAR D ++GVIILTG G K
Sbjct: 22 FEDIRYEKST-DGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDK 80
Query: 565 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 741
AFCSGGDQ +R GY D + V LNVLD Q QIR PKPV+AMVAGY++GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMM 140
Query: 742 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 921
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A +A MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL 200
Query: 922 INTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1101
+NTVVPL DLEKETV+WCRE+L+NSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1102 EEGIEGRTAYMQRRPPDFSKFPRRP 1176
EEG EGR A+ Q+R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNQKRQPDFSKFKRNP 285
>sp|P0ABU0|MENB_ECOLI Naphthoate synthase OS=Escherichia coli (strain K12)
GN=menB PE=1 SV=1
Length = 285
Score = 367 bits (941), Expect = 1e-100
Identities = 185/265 (69%), Positives = 215/265 (81%), Gaps = 2/265 (0%)
Frame = +1
Query: 385 FVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTK 564
F DI YEK+ + IAKITINRP+ RNAFRP TVKE+++A DAR D ++GVIILTG G K
Sbjct: 22 FEDIRYEKST-DGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDK 80
Query: 565 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 741
AFCSGGDQ +R GY D + V LNVLD Q QIR PKPV+AMVAGY++GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMM 140
Query: 742 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 921
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A +A MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL 200
Query: 922 INTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1101
+NTVVPL DLEKETV+WCRE+L+NSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1102 EEGIEGRTAYMQRRPPDFSKFPRRP 1176
EEG EGR A+ Q+R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNQKRQPDFSKFKRNP 285
>sp|P23966|MENB_BACSU Naphthoate synthase OS=Bacillus subtilis GN=menB PE=3
SV=2
Length = 271
Score = 349 bits (895), Expect = 3e-095
Identities = 170/266 (63%), Positives = 209/266 (78%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+ + +I+YE G IAKITINRPE NAF P+TV E++ AF DARDD +VGVI+L G G
Sbjct: 8 RTYDEILYETYNG--IAKITINRPEVHNAFTPKTVAEMIDAFADARDDQNVGVIVLAGAG 65
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
KAFCSGGDQ +R GY + + RLNVLDLQ IR +PKPV+AMV+GYA+GGGH+LH+
Sbjct: 66 DKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVSGYAIGGGHVLHI 125
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 126 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 185
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE LE+ET+KWC E+L SPTA+R LKAA NA DG AG+Q+ G+ATLL+Y
Sbjct: 186 LVNTVVPLEQLEEETIKWCEEMLEKSPTALRFLKAAFNADTDGLAGIQQFAGDATLLYYT 245
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR ++ ++R PDF +FPR P
Sbjct: 246 TDEAKEGRDSFKEKRKPDFGQFPRFP 271
>sp|Q5HQC3|MENB_STAEQ Naphthoate synthase OS=Staphylococcus epidermidis (strain
ATCC 35984 / RP62A) GN=menB PE=3 SV=1
Length = 272
Score = 346 bits (886), Expect = 3e-094
Identities = 170/266 (63%), Positives = 214/266 (80%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 9 REYDEIKYEFFEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 66
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
KAFCSGGDQ R GY +D+ RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDDIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETVKWC++I+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLEQVEDETVKWCKDIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 247 TDEAKEGRDAFKEKRNPDFDQFPKFP 272
>sp|Q8CPQ4|MENB_STAES Naphthoate synthase OS=Staphylococcus epidermidis (strain
ATCC 12228) GN=menB PE=3 SV=1
Length = 272
Score = 346 bits (886), Expect = 3e-094
Identities = 170/266 (63%), Positives = 214/266 (80%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 9 REYDEIKYEFFEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 66
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
KAFCSGGDQ R GY +D+ RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDDIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETVKWC++I+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLEQVEDETVKWCKDIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 247 TDEAKEGRDAFKEKRNPDFDQFPKFP 272
>sp|Q4L549|MENB_STAHJ Naphthoate synthase OS=Staphylococcus haemolyticus (strain
JCSC1435) GN=menB PE=3 SV=1
Length = 272
Score = 343 bits (879), Expect = 2e-093
Identities = 168/266 (63%), Positives = 213/266 (80%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD ++ VIILTG+G
Sbjct: 9 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNISVIILTGEG 66
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
KAFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLDQIEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 247 TDEAKEGRDAFKEKRDPDFDQFPKFP 272
>sp|Q6GAG7|MENB_STAAS Naphthoate synthase OS=Staphylococcus aureus (strain
MSSA476) GN=menB PE=3 SV=1
Length = 273
Score = 342 bits (875), Expect = 5e-093
Identities = 169/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVSEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q8NXA0|MENB_STAAW Naphthoate synthase OS=Staphylococcus aureus (strain MW2)
GN=menB PE=3 SV=1
Length = 273
Score = 342 bits (875), Expect = 5e-093
Identities = 169/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVSEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q5HH38|MENB_STAAC Naphthoate synthase OS=Staphylococcus aureus (strain COL)
GN=menB PE=1 SV=1
Length = 273
Score = 341 bits (874), Expect = 7e-093
Identities = 169/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q6GI37|MENB_STAAR Naphthoate synthase OS=Staphylococcus aureus (strain
MRSA252) GN=menB PE=3 SV=1
Length = 273
Score = 341 bits (874), Expect = 7e-093
Identities = 169/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q99V48|MENB_STAAM Naphthoate synthase OS=Staphylococcus aureus (strain Mu50
/ ATCC 700699) GN=menB PE=1 SV=1
Length = 273
Score = 340 bits (871), Expect = 2e-092
Identities = 168/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q7A6A9|MENB_STAAN Naphthoate synthase OS=Staphylococcus aureus (strain N315)
GN=menB PE=1 SV=1
Length = 273
Score = 340 bits (871), Expect = 2e-092
Identities = 168/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYEFYEG--IAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q49WG8|MENB_STAS1 Naphthoate synthase OS=Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 / DSM 20229) GN=menB PE=3 SV=1
Length = 272
Score = 340 bits (870), Expect = 2e-092
Identities = 166/266 (62%), Positives = 211/266 (79%), Gaps = 2/266 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
+E+ +I YE G IAK+TINRPE RNAF P TV+E++ AF ARDD + VIILTG+G
Sbjct: 9 REYKEIKYELYDG--IAKVTINRPEVRNAFTPNTVQEMIDAFTRARDDQRISVIILTGEG 66
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
KAFCSGGDQ +R GY + + RLNVLDLQ IR +PKPV+AMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVRGYAIGGGNVLNV 126
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+NTVVPL+ +E ETV+WC+E+ ++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLDQVEDETVQWCQEMKQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1099 TEEGIEGRTAYMQRRPPDFSKFPRRP 1176
T+E EGR A+ ++R PDF +FP+ P
Sbjct: 247 TDEAKEGRDAFKEKRDPDFDQFPKFP 272
>sp|Q9TM10|MENB_CYACA Naphthoate synthase OS=Cyanidium caldarium GN=menB PE=3
SV=1
Length = 268
Score = 305 bits (779), Expect = 7e-082
Identities = 151/262 (57%), Positives = 198/262 (75%), Gaps = 2/262 (0%)
Frame = +1
Query: 379 KEFVDIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKG 558
K+F+DI Y K + I++I I+RP+ NAFRP+T+ E++ AF D+R+DSS+GV+IL+G G
Sbjct: 7 KDFIDIKYIKQ--DQISEIIISRPQVLNAFRPRTINEIIAAFYDSREDSSIGVVILSGHG 64
Query: 559 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 738
++AFC GGDQ +R+ GY D LNVL+LQ IR PKPVIA V+GYAVGGG IL+M
Sbjct: 65 SRAFCVGGDQKIRSKTGYIDEKGRSSLNVLELQRIIRTFPKPVIAKVSGYAVGGGQILNM 124
Query: 739 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 918
+CDLTIA++NA+ GQ+GPKVGSFDAGYGS+ M+R++G KKARE+WF Y A EA KMG
Sbjct: 125 MCDLTIASENAVLGQSGPKVGSFDAGYGSAYMARIIGQKKARELWFTCYQYDAFEAYKMG 184
Query: 919 LINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1098
L+N VV +EDL+ +K +IL SP AIR LK++LNA DG +GLQEL G +T+LFY
Sbjct: 185 LVNWVVKIEDLDSYAIKLATDILNKSPLAIRFLKSSLNADCDGQSGLQELAGYSTMLFYM 244
Query: 1099 TEEGIEGRTAYMQRRPPDFSKF 1164
+ EG EG A+++ R PDFSKF
Sbjct: 245 SAEGQEGHRAFLENREPDFSKF 266
>sp|P64017|ECHA8_MYCBO Probable enoyl-CoA hydratase echA8 OS=Mycobacterium bovis
GN=echA8 PE=3 SV=1
Length = 257
Score = 126 bits (316), Expect = 4e-028
Identities = 86/247 (34%), Positives = 127/247 (51%), Gaps = 13/247 (5%)
Frame = +1
Query: 433 ITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTKAFCSGGDQALRTSDGY 612
IT+NRP+ NA Q + E+ A + DD +G II+TG KAF +G D +
Sbjct: 17 ITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITG-SAKAFAAGADIKEMADLTF 75
Query: 613 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 792
AD +R P IA VAGYA+GGG L M+CD+ IAAD A FGQ
Sbjct: 76 ADAFTADFFATWGKLAAVR---TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEI 132
Query: 793 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINTVVPLEDLEKETVKW 972
K+G GS ++R +G KA ++ R A+EA++ GL++ VVP +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT 192
Query: 973 CREILRNSPTAIRVLKAALN-----AVDDGHAGLQELGGNATLLFYGTEEGIEGRTAYMQ 1137
I + S +A R+ K A+N ++ +G + L +A + TE+ EG A+++
Sbjct: 193 ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA----FATEDQSEGMAAFIE 248
Query: 1138 RRPPDFS 1158
+R P F+
Sbjct: 249 KRAPQFT 255
>sp|P64016|ECHA8_MYCTU Probable enoyl-CoA hydratase echA8 OS=Mycobacterium
tuberculosis GN=echA8 PE=1 SV=1
Length = 257
Score = 126 bits (316), Expect = 4e-028
Identities = 86/247 (34%), Positives = 127/247 (51%), Gaps = 13/247 (5%)
Frame = +1
Query: 433 ITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTKAFCSGGDQALRTSDGY 612
IT+NRP+ NA Q + E+ A + DD +G II+TG KAF +G D +
Sbjct: 17 ITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITG-SAKAFAAGADIKEMADLTF 75
Query: 613 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 792
AD +R P IA VAGYA+GGG L M+CD+ IAAD A FGQ
Sbjct: 76 ADAFTADFFATWGKLAAVR---TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEI 132
Query: 793 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINTVVPLEDLEKETVKW 972
K+G GS ++R +G KA ++ R A+EA++ GL++ VVP +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT 192
Query: 973 CREILRNSPTAIRVLKAALN-----AVDDGHAGLQELGGNATLLFYGTEEGIEGRTAYMQ 1137
I + S +A R+ K A+N ++ +G + L +A + TE+ EG A+++
Sbjct: 193 ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA----FATEDQSEGMAAFIE 248
Query: 1138 RRPPDFS 1158
+R P F+
Sbjct: 249 KRAPQFT 255
>sp|P52046|CRT_CLOAB 3-hydroxybutyryl-CoA dehydratase OS=Clostridium
acetobutylicum GN=crt PE=3 SV=1
Length = 261
Score = 124 bits (309), Expect = 2e-027
Identities = 86/262 (32%), Positives = 138/262 (52%), Gaps = 24/262 (9%)
Frame = +1
Query: 391 DIIYEKAAGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTKAF 570
++I EK +A +TINRP+ NA T+KE+ + +DS V +ILTG G K+F
Sbjct: 5 NVILEKEG--KVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSF 62
Query: 571 CSGGD----QALRTSDGYADPNDVGRLNVLDLQV--QIRRLPKPVIAMVAGYAVGGGHIL 732
+G D + + T +G + +L +V ++ L KPVIA V G+A+GGG +
Sbjct: 63 VAGADISEMKEMNTIEG-------RKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEI 115
Query: 733 HMVCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADK 912
M CD+ IA+ NA FGQ +G G+ +SRLVG A+++ F + A EA +
Sbjct: 116 AMSCDIRIASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALR 175
Query: 913 MGLINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNA-----VDDGHAGLQELGGN 1077
+GL+N VV +L + +I+ N+P A+++ K A+N +D A E G
Sbjct: 176 IGLVNKVVEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGE 235
Query: 1078 ATLLFYGTEEGIEGRTAYMQRR 1143
+ TE+ + TA++++R
Sbjct: 236 C----FSTEDQKDAMTAFIEKR 253
>sp|O07137|ECHA8_MYCLE Probable enoyl-CoA hydratase echA8 OS=Mycobacterium
leprae GN=echA8 PE=3 SV=1
Length = 257
Score = 119 bits (298), Expect = 4e-026
Identities = 85/245 (34%), Positives = 125/245 (51%), Gaps = 9/245 (3%)
Frame = +1
Query: 433 ITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTKAFCSGGDQALRTSDGY 612
IT+NRP+ NA Q + E+ A + D VG I++TG K F +G D S +
Sbjct: 17 ITLNRPQALNALNSQMMNEITNAAKELDIDPDVGAILITG-SPKVFAAGADIKEMASLTF 75
Query: 613 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 792
D D + +R P+IA VAGYA+GGG L M+CDL IAAD A FGQ
Sbjct: 76 TDAFDADFFSAWGKLAAVR---TPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEI 132
Query: 793 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINTVVPLEDLEKETVKW 972
K+G GS ++R +G KA ++ R A+EA++ GL++ VV +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAV 192
Query: 973 CREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG---TEEGIEGRTAYMQRR 1143
I + S +A R+ K A+N + L E + LF+ T++ EG A++++R
Sbjct: 193 ATTISQMSRSATRMAKEAVNR--SFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFIEKR 250
Query: 1144 PPDFS 1158
P F+
Sbjct: 251 APQFT 255
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 185,567,659,578
Number of Sequences: 518415
Number of Extensions: 185567659578
Number of Successful Extensions: 1125298771
Number of sequences better than 0.0: 0
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