BLASTX 7.6.2
Query= UN49410 /QuerySize=1059
(1058 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=A... 364 6e-100
sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stram... 295 4e-079
sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium ... 274 1e-072
sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium ... 263 2e-069
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 261 7e-069
sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter o... 126 3e-028
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 121 9e-027
sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia co... 121 1e-026
sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia co... 121 1e-026
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 121 1e-026
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 121 1e-026
sp|P50842|KDUD_BACSU 2-dehydro-3-deoxy-D-gluconate 5-dehydrogena... 120 2e-026
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 119 4e-026
sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase BacC... 116 5e-025
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 116 5e-025
sp|Q8GAV9|CPNA_COMS9 Cyclopentanol dehydrogenase OS=Comamonas sp... 113 3e-024
sp|Q937L4|CPNA_COMTE Cyclopentanol dehydrogenase OS=Comamonas te... 113 3e-024
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 112 5e-024
sp|P76633|YGCW_ECOLI Uncharacterized oxidoreductase ygcW OS=Esch... 96 4e-019
sp|Q05528|KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-dehydrogena... 89 6e-017
>sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=Arabidopsis
thaliana GN=At1g07440 PE=1 SV=1
Length = 266
Score = 364 bits (934), Expect = 6e-100
Identities = 180/266 (67%), Positives = 211/266 (79%), Gaps = 1/266 (0%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M E +RWSL+ T LVTGG GIG+AIVEE A FGA+IH C +E LN+ LS W+K
Sbjct: 1 MAGAEQSQRWSLKAKTVLVTGGTKGIGHAIVEEFAGFGAVIHTCARNEYELNECLSKWQK 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHI 691
KGFQV+GS+CD S RPERE LMQTVS MF GKL IL+NN+G IR KPT +Y A+DFSFHI
Sbjct: 61 KGFQVTGSVCDASLRPEREKLMQTVSSMFGGKLDILINNLGAIRSKPTLDYTAEDFSFHI 120
Query: 690 STNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLAC 511
STNLESAYHLSQL+HPLLKASG G+I+ SS+ GVVS GS+Y +KGA+NQL+R+LAC
Sbjct: 121 STNLESAYHLSQLAHPLLKASGCGNIIFMSSIAGVVSASVGSIYSATKGALNQLARNLAC 180
Query: 510 EWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLP 331
EWA+DGIR N+VAP I T + V D +KK + SR PL R GEP+EV+SLVAFLC+P
Sbjct: 181 EWASDGIRANAVAPAVIATPLAEAVYDDE-FKKVVISRKPLGRFGEPEEVSSLVAFLCMP 239
Query: 330 AASYITGQTICVDGGLTVNGFSYQPK 253
AASYITGQTICVDGGLTVNGFSYQP+
Sbjct: 240 AASYITGQTICVDGGLTVNGFSYQPQ 265
>sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stramonium PE=2
SV=1
Length = 268
Score = 295 bits (754), Expect = 4e-079
Identities = 148/258 (57%), Positives = 188/258 (72%), Gaps = 3/258 (1%)
Frame = -3
Query: 1032 DKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVS 853
D+RWSL+GMTALVTGG GIGYAIVEELA+FGA ++ C S+ L++ L W +KGF+VS
Sbjct: 10 DRRWSLRGMTALVTGGTRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFKVS 69
Query: 852 GSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLES 673
G +CDVSS +R+TLM++V+ F+GKL+IL+NN G K T + A+D+S + TN E+
Sbjct: 70 GPVCDVSSISQRQTLMESVTSSFNGKLNILINNAGTTIPKEATNFTAEDYSIIMGTNFEA 129
Query: 672 AYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDG 493
+Y+L QL+HPLLKASG SIV NSS GV+++ S+Y SKGA+NQ+++SLACEWA D
Sbjct: 130 SYNLCQLAHPLLKASGNASIVFNSSAAGVIAVPLSSIYAASKGAINQVTKSLACEWAKDS 189
Query: 492 IRTNSVAPNFILTDMTAPVLGDVCYKK---SLFSRTPLARAGEPKEVASLVAFLCLPAAS 322
IR N+VAP I T + KK SL R P+ RAGEP EV+SLV +LCLP AS
Sbjct: 190 IRVNAVAPWIINTPIIEAACQVPSQKKNIESLIGRAPMKRAGEPSEVSSLVTYLCLPTAS 249
Query: 321 YITGQTICVDGGLTVNGF 268
YITGQ ICVDGG TVNGF
Sbjct: 250 YITGQIICVDGGYTVNGF 267
>sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium GN=TR1 PE=1
SV=1
Length = 273
Score = 274 bits (699), Expect = 1e-072
Identities = 137/264 (51%), Positives = 184/264 (69%), Gaps = 4/264 (1%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M N + RWSL+G TALVTGG+ GIGYAIVEELA GA ++ C +E L++ L W +
Sbjct: 8 MMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWRE 67
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHI 691
KG V GS+CD+ SR ER+ LMQTV+ +FDGKL+ILVNN G + K ++ D++ +
Sbjct: 68 KGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIM 127
Query: 690 STNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLAC 511
TN E+AYHLSQ+++PLLKAS G+++ SS+ G ++ SLY SKGA+NQ+++SLAC
Sbjct: 128 GTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLAC 187
Query: 510 EWATDGIRTNSVAPNFILTDMTAPVLGDVCYKK----SLFSRTPLARAGEPKEVASLVAF 343
EWA D IR NSVAP ILT + + ++K + +TP+ RAG+P+EV++L+AF
Sbjct: 188 EWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAF 247
Query: 342 LCLPAASYITGQTICVDGGLTVNG 271
LC PAASYITGQ I DGG T NG
Sbjct: 248 LCFPAASYITGQIIWADGGFTANG 271
>sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium GN=TR2 PE=1
SV=1
Length = 260
Score = 263 bits (671), Expect = 2e-069
Identities = 135/257 (52%), Positives = 174/257 (67%), Gaps = 3/257 (1%)
Frame = -3
Query: 1035 MDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQV 856
M RW+L+G TALVTGG+ GIGY IVEELAS GA ++ C ++ LN L+ W KGF+V
Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKV 60
Query: 855 SGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLE 676
S+CD+SSR ER+ LM TV+ F GKL+ILVNN G + K +Y +D+S +S N E
Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFE 120
Query: 675 SAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATD 496
+AYHLS L+HP LKAS G++V SSV G +++ ++YG +KGAM+QL+R LA EWA D
Sbjct: 121 AAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKD 180
Query: 495 GIRTNSVAPNFILTDMTAPVLGDVCYKKS---LFSRTPLARAGEPKEVASLVAFLCLPAA 325
IR N V P I T + + D K++ L R L R GEPKE+A++VAFLC PAA
Sbjct: 181 NIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAA 240
Query: 324 SYITGQTICVDGGLTVN 274
SY+TGQ I VDGGL N
Sbjct: 241 SYVTGQIIYVDGGLMAN 257
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 261 bits (666), Expect = 7e-069
Identities = 134/258 (51%), Positives = 173/258 (67%), Gaps = 3/258 (1%)
Frame = -3
Query: 1035 MDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQV 856
M RW+L+G TALVTGG+ GIGY IVEELA+ GA ++ C ++ L++ L+ W KGF V
Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNV 60
Query: 855 SGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLE 676
S+CD+SSR ERE M+TVS F GKL+ILVNN G + K +Y +D+S +S N E
Sbjct: 61 EASVCDLSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFE 120
Query: 675 SAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATD 496
+AYHLS L+HP LKAS G++V SS+ G ++ ++YG +KGAM+QL+R LA EWA D
Sbjct: 121 AAYHLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKD 180
Query: 495 GIRTNSVAPNFILTDMTAPVLGDVCYKKS---LFSRTPLARAGEPKEVASLVAFLCLPAA 325
IR N V P I T M + D K++ L R L R GEPKE+A++VAFLC PAA
Sbjct: 181 NIRVNGVGPGVIATSMVEMTIQDPEQKENLDKLIDRCALRRMGEPKELAAVVAFLCFPAA 240
Query: 324 SYITGQTICVDGGLTVNG 271
SY+TGQ I VDGG NG
Sbjct: 241 SYVTGQIIYVDGGFMANG 258
>sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter oxydans GN=gno
PE=1 SV=1
Length = 256
Score = 126 bits (316), Expect = 3e-028
Identities = 76/250 (30%), Positives = 132/250 (52%), Gaps = 1/250 (0%)
Frame = -3
Query: 1023 WSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVSGSI 844
+SL G ALVTG + GIG + + LA +GA + + + L+ + S +E +G + S ++
Sbjct: 7 FSLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAV 66
Query: 843 CDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYH 664
DV+ + + + + G + IL+NN G R P E+ D+ +STN+ + +
Sbjct: 67 FDVTDQDAVIDGVAAIERDM-GPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFF 125
Query: 663 LSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRT 484
+ Q + G G IV SV ++ + Y +KGA+ L++ +A +W G++
Sbjct: 126 VGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQI 185
Query: 483 NSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQT 304
N +AP + T+MT ++ D + L RTP R G+ +E+ FL A+S++ GQ
Sbjct: 186 NGLAPGYFATEMTERLVADEEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRASSFVNGQV 245
Query: 303 ICVDGGLTVN 274
+ VDGG+TV+
Sbjct: 246 LMVDGGITVS 255
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 121 bits (303), Expect = 9e-027
Identities = 84/259 (32%), Positives = 135/259 (52%), Gaps = 8/259 (3%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M + M +R L ALVT GIG+AI LA GA + V + ++++++ +
Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDF 703
+G V+G++C V +RE L+ T K+ G + ILV+N L TE V D
Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATAVKLHGG-IDILVSNAAVNPFFGSLMDVTEEVWDK- 118
Query: 702 SFHISTNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSR 523
+ N+++ +++ P ++ G GS+V+ SS+ S Y +SK A+ L++
Sbjct: 119 --TLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 176
Query: 522 SLACEWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAF 343
+LA E A IR N +AP I T + + D ++S+ + R GEP++ A +V+F
Sbjct: 177 TLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSF 236
Query: 342 LCLPAASYITGQTICVDGG 286
LC ASYITG+T+ V GG
Sbjct: 237 LCSEDASYITGETVVVGGG 255
>sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia coli O6 GN=idnO
PE=3 SV=1
Length = 254
Score = 121 bits (302), Expect = 1e-026
Identities = 72/249 (28%), Positives = 126/249 (50%), Gaps = 1/249 (0%)
Frame = -3
Query: 1023 WSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVSGSI 844
+SL G L+TG A GIG+ + L +GA I + DI+ ++ ++G Q +
Sbjct: 5 FSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAP 64
Query: 843 CDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYH 664
+V+ + E + ++ + K G + +LVNN G R P TE+ +++ I+ N + +
Sbjct: 65 FNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFL 123
Query: 663 LSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRT 484
+SQ + G ++ S+ + + + Y SKGA+ L+R + E A I+
Sbjct: 124 VSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQV 183
Query: 483 NSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQT 304
N +AP + T+MT ++ D + L RTP AR G+P+E+ FL A+ ++ G
Sbjct: 184 NGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHL 243
Query: 303 ICVDGGLTV 277
+ VDGG+ V
Sbjct: 244 LFVDGGMLV 252
>sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia coli (strain K12)
GN=idnO PE=3 SV=1
Length = 254
Score = 121 bits (302), Expect = 1e-026
Identities = 72/249 (28%), Positives = 126/249 (50%), Gaps = 1/249 (0%)
Frame = -3
Query: 1023 WSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVSGSI 844
+SL G L+TG A GIG+ + L +GA I + DI+ ++ ++G Q +
Sbjct: 5 FSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAP 64
Query: 843 CDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYH 664
+V+ + E + ++ + K G + +LVNN G R P TE+ +++ I+ N + +
Sbjct: 65 FNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFL 123
Query: 663 LSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRT 484
+SQ + G ++ S+ + + + Y SKGA+ L+R + E A I+
Sbjct: 124 VSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQV 183
Query: 483 NSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQT 304
N +AP + T+MT ++ D + L RTP AR G+P+E+ FL A+ ++ G
Sbjct: 184 NGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHL 243
Query: 303 ICVDGGLTV 277
+ VDGG+ V
Sbjct: 244 LFVDGGMLV 252
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 121 bits (301), Expect = 1e-026
Identities = 81/254 (31%), Positives = 131/254 (51%), Gaps = 8/254 (3%)
Frame = -3
Query: 1035 MDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQV 856
M +R L ALVT GIG+AI LA GA + V + ++++++ + +G V
Sbjct: 6 MARRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSV 65
Query: 855 SGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDFSFHIS 688
+G++C V +RE L+ T K+ G + IL++N L E V D +
Sbjct: 66 TGTVCHVGKAEDRERLVATAVKLHGG-VDILISNAAVSPFFGSLMDVPEEVWDKI---LD 121
Query: 687 TNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACE 508
N+++ L++ P + G GSIV+ SS+ Y +SK A+ L+++LA E
Sbjct: 122 VNVKATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALE 181
Query: 507 WATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPA 328
A +R N +AP I T + + D ++S+ + + R G+P+E A +V+FLC
Sbjct: 182 LAESNVRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSED 241
Query: 327 ASYITGQTICVDGG 286
ASYITG+T+ V GG
Sbjct: 242 ASYITGETVVVAGG 255
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 121 bits (301), Expect = 1e-026
Identities = 83/259 (32%), Positives = 135/259 (52%), Gaps = 8/259 (3%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M + M +R L ALVT GIG+AI LA GA + V + ++++++ +
Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDF 703
+G V+G++C V +RE L+ T K+ G + ILV+N + TE V D
Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATAVKLHGG-IDILVSNAAVNPFFGSIMDVTEEVWDK- 118
Query: 702 SFHISTNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSR 523
+ N+++ +++ P ++ G GS+V+ SS+ S Y +SK A+ L++
Sbjct: 119 --TLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 176
Query: 522 SLACEWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAF 343
+LA E A IR N +AP I T + + D ++S+ + R GEP++ A +V+F
Sbjct: 177 TLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSF 236
Query: 342 LCLPAASYITGQTICVDGG 286
LC ASYITG+T+ V GG
Sbjct: 237 LCSEDASYITGETVVVGGG 255
>sp|P50842|KDUD_BACSU 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase OS=Bacillus
subtilis GN=kduD PE=3 SV=1
Length = 254
Score = 120 bits (300), Expect = 2e-026
Identities = 81/254 (31%), Positives = 133/254 (52%), Gaps = 19/254 (7%)
Frame = -3
Query: 1023 WSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDW----EKKGFQV 856
+SL+G TALVTG GIG I + LA GA DI T SLS+ E++G
Sbjct: 8 FSLKGKTALVTGPGTGIGQGIAKALAGAGA-----DIIGTSHTSSLSETQQLVEQEGRIF 62
Query: 855 SGSICDVSSRPERETLMQTVSKMFDGK-LSILVNNVGGIRLKPTTEYVADDFSFHISTNL 679
+ D+S + E + + +++F+ + + ILVNN G I + ++ +++ ++ NL
Sbjct: 63 TSFTLDMS---KPEAIKDSAAELFENRQIDILVNNAGIIHREKAEDFPEENWQHVLNVNL 119
Query: 678 ESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSL---YGLSKGAMNQLSRSLACE 508
S + L+QL+ + G+G I+ ++ ++S + G L Y SK A+ L++S A E
Sbjct: 120 NSLFILTQLAGRHMLKRGHGKII---NIASLLSFQGGILVPAYTASKHAVAGLTKSFANE 176
Query: 507 WATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPA 328
WA GI+ N++AP +I T T P+ D + + R P R G+ ++ FL A
Sbjct: 177 WAASGIQVNAIAPGYISTANTKPIRDDEKRNEDILKRIPAGRWGQADDIGGTAVFLASRA 236
Query: 327 ASYITGQTICVDGG 286
+ Y+ G + VDGG
Sbjct: 237 SDYVNGHILAVDGG 250
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 119 bits (297), Expect = 4e-026
Identities = 77/259 (29%), Positives = 134/259 (51%), Gaps = 8/259 (3%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M + + +R L A+VT GIG AI LA GA + + + ++++++ +
Sbjct: 1 MASSGVTRRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQA 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDF 703
+G V+G++C V +RE L+ T + G + ILV+N +L TE V D
Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVATALNLHGG-IDILVSNAAVNPFFGKLMDVTEEVWDKI 119
Query: 702 SFHISTNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSR 523
+ N+++ +++ P ++ G GS+V+ +S+ Y +SK A+ L++
Sbjct: 120 ---LDINVKAMALMTKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTK 176
Query: 522 SLACEWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAF 343
+LA E A IR N +AP I T + + D ++++ + + R G+P+E A +V+F
Sbjct: 177 NLALELAAQNIRVNCLAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSF 236
Query: 342 LCLPAASYITGQTICVDGG 286
LC ASYITG+T+ V GG
Sbjct: 237 LCSEDASYITGETVVVAGG 255
>sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase BacC OS=Bacillus
subtilis GN=bacC PE=3 SV=1
Length = 253
Score = 116 bits (288), Expect = 5e-025
Identities = 81/254 (31%), Positives = 128/254 (50%), Gaps = 21/254 (8%)
Frame = -3
Query: 1005 TALVTGGACGIGYAIVEELASFGAIIHVCDI----SETLLNKSLSDWEKKGFQVSGSICD 838
T L+TGGA GIGYA V+ + A + V DI E ++ K +D ++ D
Sbjct: 7 TVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAMIRKENND------RLHFVHTD 60
Query: 837 VSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYHLS 658
++ P + +++ F G L +L+NN G + P E +++ ++ NL + +S
Sbjct: 61 ITDEPACQNAIRSAVDKFGG-LDVLINNAGIEIVAPIHEMELSNWNKVLNVNLTGMFLMS 119
Query: 657 QLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRTNS 478
+ + + SG G+I+ SVGGVV+ Y SKG + QL+RS+A ++A IR N
Sbjct: 120 KHALKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLTRSMAVDYAKHNIRVNC 179
Query: 477 VAPNFILTDMTAP--------VLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAAS 322
V P I T + L ++ KK PL R G+P+E+A+++ FL +S
Sbjct: 180 VCPGIIDTPLNEKSFLENNEGTLEEI--KKEKAKVNPLLRLGKPEEIANVMLFLASDLSS 237
Query: 321 YITGQTICVDGGLT 280
Y+TG I DGG T
Sbjct: 238 YMTGSAITADGGYT 251
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 116 bits (288), Expect = 5e-025
Identities = 79/259 (30%), Positives = 133/259 (51%), Gaps = 8/259 (3%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M + +++R L+ ALVT GIG AI LA GA + V + ++++++ +
Sbjct: 1 MASTGVERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQG 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDF 703
+G V+G++C V +RE L+ + G + ILV+N + TE V D
Sbjct: 61 EGLSVTGTVCHVGKAEDRERLVAMAVNLHGG-VDILVSNAAVNPFFGNIIDATEEVWDKI 119
Query: 702 SFHISTNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSR 523
+ N+++ +++ P ++ G GS+++ SSVG Y +SK A+ L++
Sbjct: 120 ---LHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTK 176
Query: 522 SLACEWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAF 343
+LA E A IR N +AP I T+ + + D K+ + + R G P++ A +V+F
Sbjct: 177 NLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSF 236
Query: 342 LCLPAASYITGQTICVDGG 286
LC ASYITG+T+ V GG
Sbjct: 237 LCSEDASYITGETVVVGGG 255
>sp|Q8GAV9|CPNA_COMS9 Cyclopentanol dehydrogenase OS=Comamonas sp. (strain NCIMB
9872) GN=cpnA PE=1 SV=1
Length = 250
Score = 113 bits (281), Expect = 3e-024
Identities = 76/242 (31%), Positives = 124/242 (51%), Gaps = 1/242 (0%)
Frame = -3
Query: 999 LVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVSGSICDVSSRPE 820
LVTGGA G+G LA GA +++ D++E L ++++++ ++G + DV++
Sbjct: 10 LVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENH 69
Query: 819 RETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYHLSQLSHPL 640
+ T+ D +L LVNN G + LKP + +++ N+ S + ++
Sbjct: 70 WTGAVDTILAESD-RLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEP 128
Query: 639 LKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRTNSVAPNFI 460
++ + G IV SS+ G+V + Y SKGA+ +++ A + A IR NSV P I
Sbjct: 129 MRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVI 188
Query: 459 LTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQTICVDGGLT 280
T MT +L ++L T L RA +P EV+ V FL AS++ G + VDGG T
Sbjct: 189 ATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYT 248
Query: 279 VN 274
N
Sbjct: 249 AN 250
>sp|Q937L4|CPNA_COMTE Cyclopentanol dehydrogenase OS=Comamonas testosteroni
GN=cpnA PE=3 SV=1
Length = 250
Score = 113 bits (281), Expect = 3e-024
Identities = 76/242 (31%), Positives = 124/242 (51%), Gaps = 1/242 (0%)
Frame = -3
Query: 999 LVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEKKGFQVSGSICDVSSRPE 820
LVTGGA G+G LA GA +++ D++E L ++++++ ++G + DV++
Sbjct: 10 LVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENH 69
Query: 819 RETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYHLSQLSHPL 640
+ T+ D +L LVNN G + LKP + +++ N+ S + ++
Sbjct: 70 WTGAVDTILAESD-RLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEP 128
Query: 639 LKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIRTNSVAPNFI 460
++ + G IV SS+ G+V + Y SKGA+ +++ A + A IR NSV P I
Sbjct: 129 MRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVI 188
Query: 459 LTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQTICVDGGLT 280
T MT +L ++L T L RA +P EV+ V FL AS++ G + VDGG T
Sbjct: 189 ATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYT 248
Query: 279 VN 274
N
Sbjct: 249 AN 250
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 112 bits (279), Expect = 5e-024
Identities = 76/259 (29%), Positives = 131/259 (50%), Gaps = 8/259 (3%)
Frame = -3
Query: 1050 MQNKEMDKRWSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCDISETLLNKSLSDWEK 871
M + + ++ L ALVT GIG AI LA GA + + + ++++++ +
Sbjct: 1 MASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQG 60
Query: 870 KGFQVSGSICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGI----RLKPTTEYVADDF 703
+G V+G +C V +RE L+ K+ G + ILV+N L TE V +
Sbjct: 61 EGLSVTGVVCHVGKAEDREKLVNMALKLHQG-IDILVSNAAVNPFFGNLMDVTEEV---W 116
Query: 702 SFHISTNLESAYHLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSR 523
+ +S N+ ++ + + P ++ G GS+V+ SSV G V Y +SK A+ L++
Sbjct: 117 NKVLSINVTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTK 176
Query: 522 SLACEWATDGIRTNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAF 343
+ A E A IR N +AP I T ++ + + ++ + + R G+P++ +V+F
Sbjct: 177 NFAAELAPKNIRVNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSF 236
Query: 342 LCLPAASYITGQTICVDGG 286
LC ASYI G+T+ V GG
Sbjct: 237 LCSEDASYINGETVVVGGG 255
>sp|P76633|YGCW_ECOLI Uncharacterized oxidoreductase ygcW OS=Escherichia coli
(strain K12) GN=ygcW PE=3 SV=2
Length = 261
Score = 96 bits (237), Expect = 4e-019
Identities = 66/250 (26%), Positives = 117/250 (46%), Gaps = 4/250 (1%)
Frame = -3
Query: 1023 WSLQGMTALVTGGACGIGYAIVEELASFGAIIHVCD-ISETLLNKSLSDWEKKGFQVSGS 847
+SL+G TA+VTGG G+G A LA GA I + + + K + EK+G +V
Sbjct: 14 FSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMI--EKQGVEVDFM 71
Query: 846 ICDVSSRPERETLMQTVSKMFDGKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAY 667
+++ + ++ + F G + ILVNN G +L ++ D+ I NL +A+
Sbjct: 72 QVGITAEGAPQKIIAACCERF-GTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAF 130
Query: 666 HLSQLSHPLLKASGYGSIVMNSSVGGVVSMECGSLYGLSKGAMNQLSRSLACEWATDGIR 487
LS + ++ G I+ S+ + + Y +K A+ +++ E I+
Sbjct: 131 ELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQ 190
Query: 486 TNSVAPNFILTDMTAPVLGDVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQ 307
N +AP + TD+T + + + P R G+ +++ FL PA++Y+ G
Sbjct: 191 VNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGH 250
Query: 306 TICVDGGLTV 277
+ VDGG V
Sbjct: 251 LLVVDGGYLV 260
>sp|Q05528|KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase OS=Dickeya
dadantii (strain 3937) GN=kduD PE=1 SV=1
Length = 253
Score = 89 bits (218), Expect = 6e-017
Identities = 53/168 (31%), Positives = 86/168 (51%), Gaps = 5/168 (2%)
Frame = -3
Query: 780 GKLSILVNNVGGIRLKPTTEYVADDFSFHISTNLESAYHLSQLSHPLLKASGYGSIVMNS 601
GK+ ILVNN G IR + E+ ++ ++ N++S + +SQ G+G ++N
Sbjct: 84 GKVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQTVARQFIKQGHGGKIIN- 142
Query: 600 SVGGVVSMECG---SLYGLSKGAMNQLSRSLACEWATDGIRTNSVAPNFILTDMTAPVLG 430
+ ++S + G Y SK + ++R +A EWA I N++AP ++ T+ T V
Sbjct: 143 -IASMLSFQGGIPVPSYTASKKRVMGITRIVANEWAKHNINVNAIAPGYMATNNTQHVRA 201
Query: 429 DVCYKKSLFSRTPLARAGEPKEVASLVAFLCLPAASYITGQTICVDGG 286
D K + R P R G P+++ FL A+ Y+ G TI VDGG
Sbjct: 202 DQDRSKEILDRIPAGRWGLPQDLQGPAVFLASSASDYVNGYTIAVDGG 249
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 185,567,659,578
Number of Sequences: 518415
Number of Extensions: 185567659578
Number of Successful Extensions: 1125298771
Number of sequences better than 0.0: 0
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