BLASTX 7.6.2
Query= UN50066 /QuerySize=1399
(1398 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54PY7|M2OM_DICDI Probable mitochondrial 2-oxoglutarate/malat... 220 3e-056
sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate carrier... 212 5e-054
sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate carrier... 211 2e-053
sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier... 209 6e-053
sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carrier p... 205 7e-052
sp|Q9CR58|KMCP1_MOUSE Kidney mitochondrial carrier protein 1 OS=... 182 6e-045
sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier OS=Homo ... 179 4e-044
sp|O95258|UCP5_HUMAN Brain mitochondrial carrier protein 1 OS=Ho... 179 7e-044
sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier OS=Mus m... 176 3e-043
sp|P56500|UCP2_RAT Mitochondrial uncoupling protein 2 OS=Rattus ... 176 3e-043
sp|Q9Z2B2|UCP5_MOUSE Brain mitochondrial carrier protein 1 OS=Mu... 176 3e-043
sp|P70406|UCP2_MOUSE Mitochondrial uncoupling protein 2 OS=Mus m... 176 6e-043
sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 OS=Sus scr... 174 1e-042
sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis... 174 1e-042
sp|Q3SZI5|UCP2_BOVIN Mitochondrial uncoupling protein 2 OS=Bos t... 174 2e-042
sp|O97649|UCP3_PIG Mitochondrial uncoupling protein 3 OS=Sus scr... 173 4e-042
sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos t... 172 6e-042
sp|Q5R5A8|UCP2_PONAB Mitochondrial uncoupling protein 2 OS=Pongo... 172 8e-042
sp|Q9N2J1|UCP2_CANFA Mitochondrial uncoupling protein 2 OS=Canis... 171 2e-041
sp|P55851|UCP2_HUMAN Mitochondrial uncoupling protein 2 OS=Homo ... 171 2e-041
>sp|Q54PY7|M2OM_DICDI Probable mitochondrial 2-oxoglutarate/malate carrier
protein OS=Dictyostelium discoideum GN=ucpC PE=3 SV=1
Length = 318
Score = 220 bits (558), Expect = 3e-056
Identities = 116/251 (46%), Positives = 164/251 (65%), Gaps = 3/251 (1%)
Frame = +3
Query: 510 PRVGIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPL 689
P+ G + + I + EG L+ G+SA++LRQ Y+TTR GLYD++K + K +P
Sbjct: 63 PKRGALKMLVHINQTEGFFTLYKGLSASLLRQATYTTTRFGLYDLIK-DIVAKDDKPLPF 121
Query: 690 TRKLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTS 869
T+K+ G ++G GA VG PAD+ MVRMQADG+LP RRNYK+V D I ++ + EG+ S
Sbjct: 122 TQKIMVGMLSGAGGAIVGTPADLTMVRMQADGKLPFNLRRNYKNVFDGIFRISKEEGIIS 181
Query: 870 LWRGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNP 1049
LW+G S + RAM +TA Q+++YD K+ +L G D + TH+ +S A FVA+VA++P
Sbjct: 182 LWKGCSPNLIRAMFMTAGQVSSYDQTKQLMLASGYFHDDIKTHLIASTTAAFVAAVATSP 241
Query: 1050 VDVIKTRVMNM-KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILF 1226
+DVIKTR+MN K V G+ YKG DC KT+RAEG A YKGF P R P T++ F
Sbjct: 242 LDVIKTRIMNSPKTVTGEL-QYKGTFDCLSKTLRAEGFKAFYKGFNPYFMRLGPQTILTF 300
Query: 1227 VTLEQVKKVLK 1259
+ +EQ+ + K
Sbjct: 301 IFVEQLNILWK 311
>sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate carrier protein OS=Bos
taurus GN=SLC25A11 PE=1 SV=3
Length = 314
Score = 212 bits (539), Expect = 5e-054
Identities = 106/239 (44%), Positives = 156/239 (65%), Gaps = 1/239 (0%)
Frame = +3
Query: 543 IIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIAG 722
I+R EG R +++G+SA +LRQ Y+TTR+G+Y +L + T + K G AG
Sbjct: 71 ILRAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAG 130
Query: 723 GIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTINR 902
GA VG PA+VA++RM ADGRLP+ RR YK+V +A+ ++V+ EGV +LWRG T+ R
Sbjct: 131 ATGAFVGTPAEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMAR 190
Query: 903 AMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMNM 1082
A++V A+QLA+Y K+ +L+ G D ++ H +S +G V + AS PVD++KTR+ NM
Sbjct: 191 AVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNM 250
Query: 1083 KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKVLK 1259
+++ GK P YK +D +K VR EG +L+KGF P +R P TV+ F+ LEQ+ K K
Sbjct: 251 RMIDGK-PEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYK 308
>sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus
musculus GN=Slc25a11 PE=1 SV=3
Length = 314
Score = 211 bits (535), Expect = 2e-053
Identities = 105/239 (43%), Positives = 154/239 (64%), Gaps = 1/239 (0%)
Frame = +3
Query: 543 IIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIAG 722
I++ EG + +++G+SA +LRQ Y+TTR+G+Y +L + T + K G AG
Sbjct: 71 ILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAG 130
Query: 723 GIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTINR 902
GA VG PA+VA++RM ADGRLP RR YK+V +A+ ++ R EGV +LWRG T+ R
Sbjct: 131 ATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMAR 190
Query: 903 AMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMNM 1082
A++V A+QLA+Y K+ +L+ G D ++ H +S +G V + AS PVD++KTR+ NM
Sbjct: 191 AVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNM 250
Query: 1083 KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKVLK 1259
+++ GK P YK +D LK VR EG +L+KGF P +R P TV+ F+ LEQ+ K K
Sbjct: 251 RMIDGK-PEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYK 308
>sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier protein
OS=Homo sapiens GN=SLC25A11 PE=1 SV=3
Length = 314
Score = 209 bits (530), Expect = 6e-053
Identities = 105/239 (43%), Positives = 152/239 (63%), Gaps = 1/239 (0%)
Frame = +3
Query: 543 IIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIAG 722
I++ EG R +++G+SA +LRQ Y+TTR+G+Y +L + T + K G AG
Sbjct: 71 ILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAG 130
Query: 723 GIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTINR 902
GA VG PA+VA++RM ADGRLP RR YK+V +A+ ++ R EGV +LWRG T+ R
Sbjct: 131 ATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMAR 190
Query: 903 AMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMNM 1082
A++V A+QLA+Y K+ +L+ G D ++ H +S +G V + AS PVD+ KTR+ NM
Sbjct: 191 AVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNM 250
Query: 1083 KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKVLK 1259
+++ GK P YK +D K VR EG +L+KGF P +R P TV+ F+ LEQ+ K K
Sbjct: 251 RMIDGK-PEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYK 308
>sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carrier protein
OS=Rattus norvegicus GN=Slc25a11 PE=2 SV=3
Length = 314
Score = 205 bits (521), Expect = 7e-052
Identities = 104/239 (43%), Positives = 152/239 (63%), Gaps = 1/239 (0%)
Frame = +3
Query: 543 IIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIAG 722
I++ EG R +++G+SA +LRQ Y+TTR+G+Y +L + T + K G AG
Sbjct: 71 ILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAG 130
Query: 723 GIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTINR 902
GA VG PA+VA++RM ADGRLP RR YK+V +A+ ++ R EGV +LWRG T+ R
Sbjct: 131 ATGAFVGPPAEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMAR 190
Query: 903 AMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMNM 1082
A++V A+QLA+Y K+ +L+ G D ++ H + +G V + AS PVD++KTR+ NM
Sbjct: 191 AVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAIMISGLVTTAASMPVDIVKTRIQNM 250
Query: 1083 KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKVLK 1259
+++ K P YK +D LK VR EG +L+KGF P +R P TV+ F+ LEQ+ K K
Sbjct: 251 RMIDEK-PEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYK 308
>sp|Q9CR58|KMCP1_MOUSE Kidney mitochondrial carrier protein 1 OS=Mus musculus
GN=Slc25a30 PE=1 SV=1
Length = 291
Score = 182 bits (461), Expect = 6e-045
Identities = 98/247 (39%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTD-PETKSIPLTR 695
G++ RI R+EG +AL+SG++ +LRQ Y T ++G Y LK + PE ++ L
Sbjct: 51 GMLHALMRIGREEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLAVERPEDET--LLV 108
Query: 696 KLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLW 875
+ G ++G I +A+ NP DV +RMQA ++D+ + + EG LW
Sbjct: 109 NVVCGILSGVISSAIANPTDVLKIRMQAQNSAVQG------GMIDSFMSIYQQEGTRGLW 162
Query: 876 RGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVD 1055
+G S+T RA +V +L YD K+ ++ GLM D + TH SSF G V ++ASNPVD
Sbjct: 163 KGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVATHFLSSFTCGLVGALASNPVD 222
Query: 1056 VIKTRVMNMKVVA-GKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
V++TR+MN + + G+ YKG +DC L+T + EG ALYKGFWP R P+ +I F+T
Sbjct: 223 VVRTRMMNQRALRDGRCAGYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFLT 282
Query: 1233 LEQVKKV 1253
EQ+KK+
Sbjct: 283 YEQLKKL 289
>sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier OS=Homo sapiens
GN=SLC25A10 PE=1 SV=2
Length = 287
Score = 179 bits (454), Expect = 4e-044
Identities = 96/246 (39%), Positives = 143/246 (58%), Gaps = 7/246 (2%)
Frame = +3
Query: 513 RVGIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLT 692
++ + G+ R++R +G AL+SG+SA++ RQ YS TR +Y+ ++ + +P
Sbjct: 41 KLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFH 100
Query: 693 RKLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSL 872
K+ G ++G G VG PAD+ VRMQ D +LP RRNY LD + ++ R EG+ L
Sbjct: 101 EKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRL 160
Query: 873 WRGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPV 1052
+ G++M +R LVT QL+ YD K+ VL G + D + TH +SF AG A+ P+
Sbjct: 161 FSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPL 220
Query: 1053 DVIKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
DV+KTR+MN K Y+G CA++T + G +A YKG P R P TV+ FV
Sbjct: 221 DVLKTRLMNSK------GEYQGVFHCAVETAKL-GPLAFYKGLVPAGIRLIPHTVLTFVF 273
Query: 1233 LEQVKK 1250
LEQ++K
Sbjct: 274 LEQLRK 279
>sp|O95258|UCP5_HUMAN Brain mitochondrial carrier protein 1 OS=Homo sapiens
GN=SLC25A14 PE=2 SV=1
Length = 325
Score = 179 bits (452), Expect = 7e-044
Identities = 92/238 (38%), Positives = 137/238 (57%), Gaps = 7/238 (2%)
Frame = +3
Query: 540 RIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIA 719
RI ++EG AL+SG++ +LRQ Y T ++G+Y LK + + + L + G ++
Sbjct: 93 RICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVE-RLEDETLLINMICGVVS 151
Query: 720 GGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTIN 899
G I + + NP DV +RMQA G L S++ + + + EG LWRG T
Sbjct: 152 GVISSTIANPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQ 205
Query: 900 RAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMN 1079
RA +V +L YD K+ ++ G+M D ++TH SSF G ++ASNPVDV++TR+MN
Sbjct: 206 RAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMN 265
Query: 1080 MKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKV 1253
+ + G YKG VD LK + EG ALYKGFWP R P+ +I F+T EQ+K++
Sbjct: 266 QRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
>sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier OS=Mus musculus
GN=Slc25a10 PE=2 SV=2
Length = 287
Score = 176 bits (446), Expect = 3e-043
Identities = 94/246 (38%), Positives = 143/246 (58%), Gaps = 7/246 (2%)
Frame = +3
Query: 513 RVGIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLT 692
++ + G+ +++R +G AL++G+SA++ RQ YS TR +Y+ ++ T +P
Sbjct: 40 KLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFY 99
Query: 693 RKLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSL 872
K+ G I+G G VG PAD+ VRMQ D +LP + RRNY LD + ++ R E + L
Sbjct: 100 NKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKL 159
Query: 873 WRGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPV 1052
+ G++M +R LVT QL+ YD K+ VL G + D + TH SSF AG A+ P+
Sbjct: 160 FSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVSSFIAGGCATFLCQPL 219
Query: 1053 DVIKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
DV+KTR+MN K Y+G CA++T + G A +KG +P R P TV+ F+
Sbjct: 220 DVLKTRLMNSK------GEYQGVFHCAMETAKL-GPQAFFKGLFPAGIRLIPHTVLTFMF 272
Query: 1233 LEQVKK 1250
LEQ++K
Sbjct: 273 LEQLRK 278
>sp|P56500|UCP2_RAT Mitochondrial uncoupling protein 2 OS=Rattus norvegicus
GN=Ucp2 PE=2 SV=1
Length = 309
Score = 176 bits (446), Expect = 3e-043
Identities = 101/266 (37%), Positives = 149/266 (56%), Gaps = 8/266 (3%)
Frame = +3
Query: 459 LAFQTSSSSSAVHAPPPPRVGIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLY 638
L Q S A A G++G ++R EG R+L++G+ A + RQ +++ R+GLY
Sbjct: 41 LQIQGESQGLARTAASAQYRGVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLY 100
Query: 639 DILKTKWTDPETKSIPLTRKLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYK 818
D +K +T ++ + +L AG G + AV P DV VR QA R R Y+
Sbjct: 101 DSVKQFYT-KGSEHAGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQAR--AGGGRRYQ 157
Query: 819 SVLDAIAQMVRGEGVTSLWRGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTH 998
S ++A + R EG+ LW+G+S + R +V ++L TYD +K+T+L+ LM D L H
Sbjct: 158 STVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELVTYDLIKDTLLKANLMTDDLPCH 217
Query: 999 VTSSFAAGFVASVASNPVDVIKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKG 1178
TS+F AGF +V ++PVDV+KTR MN + Y A CAL +R EG A YKG
Sbjct: 218 FTSAFGAGFCTTVIASPVDVVKTRYMNSAL-----GQYHSAGHCALTMLRKEGPRAFYKG 272
Query: 1179 FWPTVSRQAPFTVILFVTLEQVKKVL 1256
F P+ R + V++FVT EQ+K+ L
Sbjct: 273 FMPSFLRLGSWNVVMFVTYEQLKRAL 298
>sp|Q9Z2B2|UCP5_MOUSE Brain mitochondrial carrier protein 1 OS=Mus musculus
GN=Slc25a14 PE=2 SV=2
Length = 325
Score = 176 bits (446), Expect = 3e-043
Identities = 90/238 (37%), Positives = 137/238 (57%), Gaps = 7/238 (2%)
Frame = +3
Query: 540 RIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIA 719
RI ++EG AL+SG++ +LRQ Y T ++G+Y LK + + + L + G ++
Sbjct: 93 RIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVE-RLEDETLLINMICGVVS 151
Query: 720 GGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTIN 899
G I + + NP DV +RMQA G L S++ + + + EG LWRG T
Sbjct: 152 GVISSTIANPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQ 205
Query: 900 RAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMN 1079
RA +V +L YD K+ ++ G++ D ++TH SSF G ++ASNPVDV++TR+MN
Sbjct: 206 RAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMN 265
Query: 1080 MKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKV 1253
+ + G YKG +D LK + EG ALYKGFWP R P+ +I F+T EQ+K++
Sbjct: 266 QRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
>sp|P70406|UCP2_MOUSE Mitochondrial uncoupling protein 2 OS=Mus musculus GN=Ucp2
PE=2 SV=1
Length = 309
Score = 176 bits (444), Expect = 6e-043
Identities = 96/246 (39%), Positives = 144/246 (58%), Gaps = 8/246 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+L++G+ A + RQ +++ R+GLYD +K +T ++ + +
Sbjct: 61 GVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHAGIGSR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
L AG G + AV P DV VR QA R R Y+S ++A + R EG+ LW+
Sbjct: 120 LLAGSTTGALAVAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWK 177
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G+S + R +V ++L TYD +K+T+L+ LM D L H TS+F AGF +V ++PVDV
Sbjct: 178 GTSPNVARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDV 237
Query: 1059 IKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLE 1238
+KTR MN + Y A CAL +R EG A YKGF P+ R + V++FVT E
Sbjct: 238 VKTRYMNSAL-----GQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292
Query: 1239 QVKKVL 1256
Q+K+ L
Sbjct: 293 QLKRAL 298
>sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 OS=Sus scrofa GN=UCP2
PE=2 SV=1
Length = 309
Score = 174 bits (441), Expect = 1e-042
Identities = 96/246 (39%), Positives = 143/246 (58%), Gaps = 8/246 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+L++G+ A + RQ +++ R+GLYD +K +T ++ + +
Sbjct: 61 GVLGTILTMVRNEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKHFYT-KGSEHAGIGSR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
L AG G + AV P DV VR QA R R Y+S +DA + R EG+ LW+
Sbjct: 120 LLAGSTTGALAVAVAQPTDVVKVRFQAQAR--AGGGRRYRSTVDAYKTIAREEGLRGLWK 177
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G+S + R +V ++L TYD +K+T+L+ LM D L H TS+F AGF +V ++PVDV
Sbjct: 178 GTSPNVARNAIVNCAELVTYDLIKDTLLKADLMTDDLPCHFTSAFGAGFCTTVIASPVDV 237
Query: 1059 IKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLE 1238
+KTR MN Y A CAL ++ EG A YKGF P+ R + V++FVT E
Sbjct: 238 VKTRYMN-----SAPGQYSSAGHCALTMLQKEGPRAFYKGFTPSFLRLGSWNVVMFVTYE 292
Query: 1239 QVKKVL 1256
Q+K+ L
Sbjct: 293 QLKRAL 298
>sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis familiaris
GN=UCP3 PE=2 SV=1
Length = 311
Score = 174 bits (441), Expect = 1e-042
Identities = 93/248 (37%), Positives = 140/248 (56%), Gaps = 9/248 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+ ++G+ A + RQ +++ R+GLYD +K +T + +T +
Sbjct: 60 GVLGTILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSITTR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
+ AG G + + P DV VR QA L R Y +DA + R EGV LW+
Sbjct: 120 ILAGCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWK 179
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G+ I R +V +++ TYD +KE +L+ L+ D H+ S+F AGF A+V ++PVDV
Sbjct: 180 GTLPNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLISAFGAGFCATVVASPVDV 239
Query: 1059 IKTRVMNMKVVAGKTPP--YKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
+KTR MN +PP Y +DC LK V EG A YKGF P+ R + V++FVT
Sbjct: 240 VKTRYMN-------SPPGQYCSPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVT 292
Query: 1233 LEQVKKVL 1256
EQ+K+ L
Sbjct: 293 YEQLKRAL 300
>sp|Q3SZI5|UCP2_BOVIN Mitochondrial uncoupling protein 2 OS=Bos taurus GN=UCP2
PE=2 SV=1
Length = 309
Score = 174 bits (439), Expect = 2e-042
Identities = 96/246 (39%), Positives = 143/246 (58%), Gaps = 8/246 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+L+SG+ A + RQ +++ R+GLYD +K +T ++ + +
Sbjct: 61 GVLGTILTMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHAGIGSR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
L AG G + AV P DV VR QA R R Y+S ++A + R EG LW+
Sbjct: 120 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAGAG--RRYQSTVEAYKTIAREEGFRGLWK 177
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G+S + R +V ++L TYD +K+T+L+ LM D L H TS+F AGF +V ++PVDV
Sbjct: 178 GTSPNVARNAIVNCAELVTYDLIKDTLLKAHLMTDDLPCHFTSAFGAGFCTTVIASPVDV 237
Query: 1059 IKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLE 1238
+KTR MN + Y A CAL ++ EG A YKGF P+ R + V++FVT E
Sbjct: 238 VKTRYMNSAL-----GQYSSAGHCALTMLQKEGPQAFYKGFMPSFLRLGSWNVVMFVTYE 292
Query: 1239 QVKKVL 1256
Q+K+ L
Sbjct: 293 QLKRAL 298
>sp|O97649|UCP3_PIG Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3
PE=2 SV=1
Length = 308
Score = 173 bits (437), Expect = 4e-042
Identities = 93/248 (37%), Positives = 138/248 (55%), Gaps = 9/248 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+ ++G+ A + RQ +++ R+GLYD +K +T + +T +
Sbjct: 57 GVLGTILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSSITTR 116
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
+ AG G + P DV VR QA R Y +DA + R EGV LW+
Sbjct: 117 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWK 176
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G I R +V +++ TYD +KE VL+ L+ D L H S+F AGF A+V ++PVDV
Sbjct: 177 GILPNITRNAIVNCAEMVTYDVIKEKVLDYHLLTDNLPCHFVSAFGAGFCATVVASPVDV 236
Query: 1059 IKTRVMNMKVVAGKTPP--YKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
+KTR MN +PP Y+ +DC LK V EG A YKGF P+ R + V++FV+
Sbjct: 237 VKTRYMN-------SPPGQYQNPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVS 289
Query: 1233 LEQVKKVL 1256
EQ+K+ L
Sbjct: 290 YEQLKRAL 297
>sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3
PE=2 SV=1
Length = 311
Score = 172 bits (435), Expect = 6e-042
Identities = 92/248 (37%), Positives = 135/248 (54%), Gaps = 9/248 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+L+SG+ A + RQ +++ R+GLYD +K +T + + +
Sbjct: 60 GVLGTILTMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSIITR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
+ AG G + P DV +R QA L R Y +DA + R EGV LW+
Sbjct: 120 ILAGCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWK 179
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G I R +V ++ TYD +KE +L+ L+ D H S+F AGF A++ ++PVDV
Sbjct: 180 GILPNITRNAIVNCGEMVTYDIIKEKLLDYHLLTDNFPCHFVSAFGAGFCATLVASPVDV 239
Query: 1059 IKTRVMNMKVVAGKTPP--YKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVT 1232
+KTR MN +PP Y DC LK V EG A YKGF P+ R + V++FVT
Sbjct: 240 VKTRYMN-------SPPGQYHSPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVT 292
Query: 1233 LEQVKKVL 1256
EQ+K+ L
Sbjct: 293 YEQMKRAL 300
>sp|Q5R5A8|UCP2_PONAB Mitochondrial uncoupling protein 2 OS=Pongo abelii GN=UCP2
PE=2 SV=1
Length = 309
Score = 172 bits (434), Expect = 8e-042
Identities = 98/260 (37%), Positives = 147/260 (56%), Gaps = 9/260 (3%)
Frame = +3
Query: 480 SSSAVHAPPPPRV-GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTK 656
S VHA + G++G ++R EG R+L++G+ A + RQ +++ R+GLYD +K
Sbjct: 47 SQGPVHATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106
Query: 657 WTDPETKSIPLTRKLAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAI 836
+T ++ + +L AG G + AV P DV VR QA R R Y+S ++A
Sbjct: 107 YT-KGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAY 163
Query: 837 AQMVRGEGVTSLWRGSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFA 1016
+ R EG LW+G+S + R +V ++L TYD +K+ +L+ LM D L H TS+F
Sbjct: 164 KTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFG 223
Query: 1017 AGFVASVASNPVDVIKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVS 1196
AGF +V ++PVDV+KTR MN + Y A CAL ++ EG A YKGF P+
Sbjct: 224 AGFCTTVIASPVDVVKTRYMNSAL-----GQYSSAGHCALTMLQKEGPRAFYKGFMPSFL 278
Query: 1197 RQAPFTVILFVTLEQVKKVL 1256
R + V++FVT EQ+K+ L
Sbjct: 279 RLGSWNVVMFVTYEQLKRAL 298
>sp|Q9N2J1|UCP2_CANFA Mitochondrial uncoupling protein 2 OS=Canis familiaris
GN=UCP2 PE=2 SV=1
Length = 309
Score = 171 bits (431), Expect = 2e-041
Identities = 94/238 (39%), Positives = 138/238 (57%), Gaps = 8/238 (3%)
Frame = +3
Query: 543 IIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRKLAAGFIAG 722
++R EG R+L+SG+ A + RQ +++ R+GLYD +K +T ++ + +L AG G
Sbjct: 69 MVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHAGIGSRLLAGSTTG 127
Query: 723 GIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWRGSSMTINR 902
+ AV P DV VR QA R R Y+S +DA + R EG LW+G+S + R
Sbjct: 128 ALAVAVAQPTDVVKVRFQAQAR--AGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNVAR 185
Query: 903 AMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDVIKTRVMNM 1082
+V ++L TYD +K+ +L+ LM D L H TS+F AGF +V ++PVDV+KTR MN
Sbjct: 186 NAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNS 245
Query: 1083 KVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLEQVKKVL 1256
+ Y A CAL ++ EG A YKGF P+ R + V++FVT EQ+K+ L
Sbjct: 246 AL-----GQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRAL 298
>sp|P55851|UCP2_HUMAN Mitochondrial uncoupling protein 2 OS=Homo sapiens GN=UCP2
PE=1 SV=1
Length = 309
Score = 171 bits (431), Expect = 2e-041
Identities = 94/246 (38%), Positives = 142/246 (57%), Gaps = 8/246 (3%)
Frame = +3
Query: 519 GIIGIGSRIIRQEGTRALFSGVSATVLRQTLYSTTRMGLYDILKTKWTDPETKSIPLTRK 698
G++G ++R EG R+L++G+ A + RQ +++ R+GLYD +K +T ++ + +
Sbjct: 61 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHASIGSR 119
Query: 699 LAAGFIAGGIGAAVGNPADVAMVRMQADGRLPLADRRNYKSVLDAIAQMVRGEGVTSLWR 878
L AG G + AV P DV VR QA R R Y+S ++A + R EG LW+
Sbjct: 120 LLAGSTTGALAVAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAYKTIAREEGFRGLWK 177
Query: 879 GSSMTINRAMLVTASQLATYDSVKETVLERGLMRDGLVTHVTSSFAAGFVASVASNPVDV 1058
G+S + R +V ++L TYD +K+ +L+ LM D L H TS+F AGF +V ++PVDV
Sbjct: 178 GTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDV 237
Query: 1059 IKTRVMNMKVVAGKTPPYKGAVDCALKTVRAEGVMALYKGFWPTVSRQAPFTVILFVTLE 1238
+KTR MN + Y A CAL ++ EG A YKGF P+ R + V++FVT E
Sbjct: 238 VKTRYMNSAL-----GQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292
Query: 1239 QVKKVL 1256
Q+K+ L
Sbjct: 293 QLKRAL 298
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 186,100,387,091
Number of Sequences: 518415
Number of Extensions: 186100387091
Number of Successful Extensions: 1135017718
Number of sequences better than 0.0: 0
|
