BLASTX 7.6.2
Query= UN50124 /QuerySize=1223
(1222 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R493|IF2A_PONAB Eukaryotic translation initiation factor 2 ... 289 3e-077
sp|P05198|IF2A_HUMAN Eukaryotic translation initiation factor 2 ... 289 4e-077
sp|Q6GL89|IF2A_XENTR Eukaryotic translation initiation factor 2 ... 289 5e-077
sp|Q5ZLX2|IF2A_CHICK Eukaryotic translation initiation factor 2 ... 288 6e-077
sp|Q7ZTK4|IF2A_XENLA Eukaryotic translation initiation factor 2 ... 287 1e-076
sp|P68102|IF2A_BOVIN Eukaryotic translation initiation factor 2 ... 287 1e-076
sp|Q6ZWX6|IF2A_MOUSE Eukaryotic translation initiation factor 2 ... 287 1e-076
sp|P68101|IF2A_RAT Eukaryotic translation initiation factor 2 su... 287 1e-076
sp|P41374|IF2A_DROME Eukaryotic translation initiation factor 2 ... 258 9e-068
sp|Q869N9|IF2A_DICDI Eukaryotic translation initiation factor 2 ... 238 1e-061
sp|P56286|IF2A_SCHPO Eukaryotic translation initiation factor 2 ... 215 5e-055
sp|P20459|IF2A_YEAST Eukaryotic translation initiation factor 2 ... 201 1e-050
sp|P20460|IF2A_PIG Eukaryotic translation initiation factor 2 su... 100 2e-020
sp|Q57581|IF2A_METJA Translation initiation factor 2 subunit alp... 89 6e-017
sp|Q973G0|IF2A_SULTO Translation initiation factor 2 subunit alp... 86 6e-016
>sp|Q5R493|IF2A_PONAB Eukaryotic translation initiation factor 2 subunit 1
OS=Pongo abelii GN=EIF2S1 PE=2 SV=1
Length = 315
Score = 289 bits (739), Expect = 3e-077
Identities = 151/329 (45%), Positives = 220/329 (66%), Gaps = 28/329 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNERVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P S+L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-SILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ ++ L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
+ P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 NMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEE 1017
D+ L M +L +N E+ GD+++ E E
Sbjct: 282 DETELARQMERLERENAEVDGDDDAEEME 310
>sp|P05198|IF2A_HUMAN Eukaryotic translation initiation factor 2 subunit 1
OS=Homo sapiens GN=EIF2S1 PE=1 SV=3
Length = 315
Score = 289 bits (738), Expect = 4e-077
Identities = 151/329 (45%), Positives = 220/329 (66%), Gaps = 28/329 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P S+L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-SILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ ++ L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
+ P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 NMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEE 1017
D+ L M +L +N E+ GD+++ E E
Sbjct: 282 DETELARQMERLERENAEVDGDDDAEEME 310
>sp|Q6GL89|IF2A_XENTR Eukaryotic translation initiation factor 2 subunit 1
OS=Xenopus tropicalis GN=eif2s1 PE=2 SV=1
Length = 315
Score = 289 bits (737), Expect = 5e-077
Identities = 150/332 (45%), Positives = 221/332 (66%), Gaps = 28/332 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEVD VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PALSCRFYQHKFPEVDDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDK++GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKDKGYIDLSKRRVSPEEALKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE LY W Y+K G+ A++AFK ++ PD + DG +
Sbjct: 122 TKDEQLESLYQRTAWVFDEKYKKPGYGAYDAFKHAVSDPDVL-------------DGLD- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ + L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +K+A++ + E
Sbjct: 168 ------LNEDERRVLIDNINRRLTPQAVKIRADIEVACYGYEGIDAVKDALRAGLSCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
+ P+KI L+APP YV+TT TL++ +G+ +L +A++V E I++ +G V+ P+ V++
Sbjct: 222 NMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMSVIKERIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEEEDT 1026
D+ L + +L +N E+ GD+++ E E T
Sbjct: 282 DETELARQLERLEKENAEVDGDDDAEEMEAKT 313
>sp|Q5ZLX2|IF2A_CHICK Eukaryotic translation initiation factor 2 subunit 1
OS=Gallus gallus GN=EIF2S1 PE=2 SV=2
Length = 315
Score = 288 bits (736), Expect = 6e-077
Identities = 152/332 (45%), Positives = 221/332 (66%), Gaps = 28/332 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PALSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P ++L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-AILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+TEE + L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LTEEERRVLIDNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
+ P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 NMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEEEDT 1026
D+ L + +L +N E+ GD+++ E E T
Sbjct: 282 DETELARQLERLERENAEVDGDDDAEEMEAKT 313
>sp|Q7ZTK4|IF2A_XENLA Eukaryotic translation initiation factor 2 subunit 1
OS=Xenopus laevis GN=eif2s1 PE=2 SV=1
Length = 315
Score = 287 bits (734), Expect = 1e-076
Identities = 148/332 (44%), Positives = 222/332 (66%), Gaps = 28/332 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEVD VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLNCRFYQHKFPEVDDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDK++GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKDKGYIDLSKRRVSPEEALKCEDKFTKSKTVYSILRHVAEVLDY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
L+ L+ W Y+K G+ A++AFK ++ PD + DG +
Sbjct: 122 TKDEQLDSLFQRTAWVFDEKYKKPGYGAYDAFKNAVSDPDIL-------------DGLD- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
++E+ + L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +K+A++ + E
Sbjct: 168 ------LSEDERRVLIDNINRRLTPQAVKIRADIEVACYGYEGIDAVKDALRAGLSCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
+ P+KI L+APP YV+TT TL++ +G+ +L +A++V E I++ +G V+ P+ V++
Sbjct: 222 NMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMSVIKERIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEEEDT 1026
D+ L + +L +N E+ GD+++ E E T
Sbjct: 282 DETELARQLERLEKENAEVDGDDDADEMEAKT 313
>sp|P68102|IF2A_BOVIN Eukaryotic translation initiation factor 2 subunit 1
OS=Bos taurus GN=EIF2S1 PE=2 SV=2
Length = 315
Score = 287 bits (733), Expect = 1e-076
Identities = 150/329 (45%), Positives = 219/329 (66%), Gaps = 28/329 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P S+L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-SILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ ++ L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 TMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEE 1017
D+ L + +L +N E+ GD+++ E E
Sbjct: 282 DETELARQLERLERENAEVDGDDDAEEME 310
>sp|Q6ZWX6|IF2A_MOUSE Eukaryotic translation initiation factor 2 subunit 1
OS=Mus musculus GN=Eif2s1 PE=1 SV=3
Length = 315
Score = 287 bits (733), Expect = 1e-076
Identities = 150/329 (45%), Positives = 219/329 (66%), Gaps = 28/329 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P S+L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-SILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ ++ L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 TMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEE 1017
D+ L + +L +N E+ GD+++ E E
Sbjct: 282 DETELARQLERLERENAEVDGDDDAEEME 310
>sp|P68101|IF2A_RAT Eukaryotic translation initiation factor 2 subunit 1
OS=Rattus norvegicus GN=Eif2s1 PE=1 SV=2
Length = 315
Score = 287 bits (733), Expect = 1e-076
Identities = 150/329 (45%), Positives = 219/329 (66%), Gaps = 28/329 (8%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSI 414
LI++GR E V+V+RVDKE+GYIDLSKRRVS E+ CE+++ KSK V+SI+RHVAE L
Sbjct: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121
Query: 415 ----DLEELYVNIGWPL---YRKHGH-AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEV 570
LE L+ W Y++ G+ A++AFK ++ P S+L SL
Sbjct: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP-SILDSLD------------- 167
Query: 571 TRVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNE 750
+ E+ ++ L+ NI RR+TPQ +KIRADIE+ C+ ++G+ +KEA++ E
Sbjct: 168 ------LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE 221
Query: 751 DCPVKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSER 930
P+KI L+APP YV+TT TL++ +G+ +L +A+AV E I++ +G V+ P+ V++
Sbjct: 222 TMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDT 281
Query: 931 DDKMLTEHMAKLRMDNEEISGDEESGEEE 1017
D+ L + +L +N E+ GD+++ E E
Sbjct: 282 DETELARQLERLERENAEVDGDDDAEEME 310
>sp|P41374|IF2A_DROME Eukaryotic translation initiation factor 2 subunit 1
OS=Drosophila melanogaster GN=eIF-2alpha PE=1 SV=1
Length = 341
Score = 258 bits (657), Expect = 9e-068
Identities = 136/331 (41%), Positives = 203/331 (61%), Gaps = 27/331 (8%)
Frame = +1
Query: 61 LECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLI 240
L R Y +YPE++ VM+ V +IA+MGAYV LLEYNNIEGMIL SELSRRRIRS++ LI
Sbjct: 3 LTSRFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLI 62
Query: 241 KVGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSID- 417
+VG+ EPV+V+RVDKE+GYIDLSKRRVS ED++ C ER+ K+K ++S++RHVA+ L +
Sbjct: 63 RVGKTEPVVVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGFEG 122
Query: 418 ---LEELYVNIGWPLYRKHGH---AFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEVTRV 579
LE+LY W +K+ + A++ FK +T P +V E
Sbjct: 123 NEKLEDLYQKTAWHFEKKYNNKTVAYDIFKQSVTDP-TVFDECNLE-------------- 167
Query: 580 VPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNEDCP 759
E K+ L+ NI+R++ +KIRADIE C+ ++G+ +K ++ K E+ P
Sbjct: 168 -----PETKEVLLSNIKRKLVSPTVKIRADIECSCYGYEGIDAVKASLTKGLELSTEELP 222
Query: 760 VKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSERDDK 939
++I L+APPLYV+TT T K G++ LE AI ++ G+ V AP+ V+ D+
Sbjct: 223 IRINLIAPPLYVMTTSTTKKTDGLKALEVAIEHIRAKTSEYDGEFKVIMAPKLVTAIDEA 282
Query: 940 MLTEHMAKLRMDNEEISGDEESGEEEEDTGM 1032
L + + +N +++GD++ + + GM
Sbjct: 283 DLARRLERAEAENAQVAGDDDEEDGADQEGM 313
>sp|Q869N9|IF2A_DICDI Eukaryotic translation initiation factor 2 subunit 1
OS=Dictyostelium discoideum GN=eif2s1 PE=1 SV=1
Length = 341
Score = 238 bits (605), Expect = 1e-061
Identities = 134/328 (40%), Positives = 202/328 (61%), Gaps = 17/328 (5%)
Frame = +1
Query: 64 ECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIK 243
+CRMYE KYPE + VM+++++I DMG YVSLLEYNNIEGMIL SE+SRRRIRS++ L++
Sbjct: 6 DCRMYEKKYPEENELVMVRIESIGDMGVYVSLLEYNNIEGMILLSEISRRRIRSINKLVR 65
Query: 244 VGRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLS---- 411
VG+ E V+V+RVDK++GYIDLSKRRV+ E+ CEER++KSK VH I+R+VA LS
Sbjct: 66 VGKTEAVVVVRVDKDKGYIDLSKRRVTPEEYAQCEERFHKSKAVHGIVRYVATKLSTEDN 125
Query: 412 -IDLEELYVNIGWPLYRKHGHAFEAFKVLLTGPDSVLGSLTREIKEVGPDGQEVTRVVPA 588
+ + LY WPLY K+GHA+EAFK+ +T P G ++ + ++V ++
Sbjct: 126 VVKTKHLYTKFVWPLYTKYGHAYEAFKLSITEPSVFNGF------DIAENERKV--LMET 177
Query: 589 VTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNEDCP--- 759
+ +++K K +R + +K H +K E ++
Sbjct: 178 IIQKLKPQPHK-VRADLEITCYDYEGIDAIKHAITASQNHALSVLKAPEDGKFDEKAFGV 236
Query: 760 VKIKLVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSERDDK 939
V IKLVAPPLYV+ +KE+G+ ++ + + V +E I K G L +K APR V DD+
Sbjct: 237 VTIKLVAPPLYVMVGTFDEKEKGLSMVGQCVDVLSEEITKKNGNLTIKAAPRIVGAVDDQ 296
Query: 940 MLTEHMAKLRMDNEEISGDEESGEEEED 1023
L + M +L ++N++ G+E ++++D
Sbjct: 297 ELRDLMEQLEVENQDGDGEEHEDDDDDD 324
>sp|P56286|IF2A_SCHPO Eukaryotic translation initiation factor 2 subunit alpha
OS=Schizosaccharomyces pombe GN=tif211 PE=1 SV=1
Length = 306
Score = 215 bits (547), Expect = 5e-055
Identities = 102/154 (66%), Positives = 126/154 (81%)
Frame = +1
Query: 67 CRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIKV 246
CRMYE+++PEVD V++ V+ I +MGAYV LLEY+NIEGM+L SELSRRRIRSV I+V
Sbjct: 6 CRMYENRFPEVDELVVVNVRQIQEMGAYVKLLEYDNIEGMVLLSELSRRRIRSVQKHIRV 65
Query: 247 GRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSIDLEE 426
GR E V+VLRVDKE+GYIDLSKRRVS ED+ CEER+NKSK VHSIMRH+AE ++ LE
Sbjct: 66 GRNEVVVVLRVDKEKGYIDLSKRRVSPEDVVKCEERFNKSKAVHSIMRHIAEKHNVPLET 125
Query: 427 LYVNIGWPLYRKHGHAFEAFKVLLTGPDSVLGSL 528
+Y IGWPLYRK+GHA++AFK+ ++ PD V L
Sbjct: 126 MYTTIGWPLYRKYGHAYDAFKLAISNPDHVFEGL 159
Score = 132 bits (330), Expect = 8e-030
Identities = 66/133 (49%), Positives = 88/133 (66%)
Frame = +1
Query: 613 LVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNEDCPVKIKLVAPPLY 792
L+ I RR+TPQP+KIRAD+E+ CF ++G+ IK A+K AE E+ P+K+KLVAPPLY
Sbjct: 170 LLAQISRRLTPQPIKIRADVEVTCFGYEGINAIKAALKAAEDVHTEEVPIKVKLVAPPLY 229
Query: 793 VLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSERDDKMLTEHMAKLRM 972
VL T LDK G++ LE+AI ++I G VK P+AVSE D+ L + M K
Sbjct: 230 VLLTNALDKSLGLKKLEEAIGAIEKSITASNGTCTVKMKPKAVSETDELELADLMKKFEK 289
Query: 973 DNEEISGDEESGE 1011
+N EISGDEE +
Sbjct: 290 ENAEISGDEEDDQ 302
>sp|P20459|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha
OS=Saccharomyces cerevisiae GN=SUI2 PE=1 SV=1
Length = 304
Score = 201 bits (509), Expect = 1e-050
Identities = 98/142 (69%), Positives = 115/142 (80%)
Frame = +1
Query: 67 CRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIKV 246
CR YE+KYPE+D VM+ V+ IA+MGAYV LLEY+NIEGMIL SELSRRRIRS+ LI+V
Sbjct: 6 CRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRV 65
Query: 247 GRIEPVMVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSIDLEE 426
G+ + +VLRVDKE+GYIDLSKRRVS EDI CEE+Y KSK VHSI+R+ AE I LEE
Sbjct: 66 GKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEE 125
Query: 427 LYVNIGWPLYRKHGHAFEAFKV 492
LY I WPL RK GHA+EAFK+
Sbjct: 126 LYKTIAWPLSRKFGHAYEAFKL 147
Score = 124 bits (309), Expect = 2e-027
Identities = 64/143 (44%), Positives = 90/143 (62%)
Frame = +1
Query: 592 TEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKKAEAAGNEDCPVKIK 771
+++V D L I +R+TPQ +KIRAD+E+ CF ++G+ IK+A+K AE E VK+K
Sbjct: 162 SKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVK 221
Query: 772 LVAPPLYVLTTQTLDKEQGIEILEKAIAVCTETIDKHKGKLVVKEAPRAVSERDDKMLTE 951
LVA PLYVLTTQ LDK++GIE LE AI TE I K+ G + P+AV+ +D L
Sbjct: 222 LVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQA 281
Query: 952 HMAKLRMDNEEISGDEESGEEEE 1020
+ +DN S D+E ++E
Sbjct: 282 LLESKELDNRSDSEDDEDESDDE 304
>sp|P20460|IF2A_PIG Eukaryotic translation initiation factor 2 subunit 1
(Fragment) OS=Sus scrofa GN=EIF2S1 PE=1 SV=2
Length = 70
Score = 100 bits (248), Expect = 2e-020
Identities = 46/66 (69%), Positives = 57/66 (86%)
Frame = +1
Query: 55 PNLECRMYESKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSS 234
P L CR Y+ K+PEV+ VM+ V++IA+MGAYVSLLEYNNIEGMIL SELSRRRIRS++
Sbjct: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61
Query: 235 LIKVGR 252
LI++GR
Sbjct: 62 LIRIGR 67
>sp|Q57581|IF2A_METJA Translation initiation factor 2 subunit alpha
OS=Methanocaldococcus jannaschii GN=eif2a PE=3 SV=1
Length = 266
Score = 89 bits (219), Expect = 6e-017
Identities = 58/195 (29%), Positives = 101/195 (51%), Gaps = 9/195 (4%)
Frame = +1
Query: 85 KYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIKVGRIEPV 264
++PE V+ VK++ GA+V LLEY EGMI SE++ ++++ +KVG+
Sbjct: 7 EFPEEGDIVIGTVKDVKPYGAFVELLEYPGKEGMIHISEVTSGWVKNIRDHVKVGQRVVA 66
Query: 265 MVLRVDKEEGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSIDLEELYVNIG 444
VLRVD+ +G+IDLS +RV+E+ + + + + + ++ AE L LEE + +G
Sbjct: 67 KVLRVDERKGHIDLSLKRVTEQQKRAKVQEWKRFQRASKMLERAAEKLGKSLEEAWEEVG 126
Query: 445 WPLYRKHGHAFEAFKVLLTGPDSVLGSL------TREIKEVGPDGQEVTRVVPAVTEEVK 606
+ L + G + AF+ ++ VL L + EV + E+T V E+K
Sbjct: 127 YLLEDEFGELYNAFETMVIEGKEVLDDLEISEEWKNVLYEVAKESIELTNVEVEGVIEMK 186
Query: 607 DAL---VKNIRRRMT 642
+K I++ +T
Sbjct: 187 SYAPDGIKQIKKALT 201
>sp|Q973G0|IF2A_SULTO Translation initiation factor 2 subunit alpha
OS=Sulfolobus tokodaii GN=eif2a PE=3 SV=1
Length = 263
Score = 86 bits (210), Expect = 6e-016
Identities = 45/133 (33%), Positives = 82/133 (61%)
Frame = +1
Query: 121 VKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIKVGRIEPVMVLRVDKEEGYI 300
VK I D G+YV+L EY N++ + +SE+S R ++++ +IK GR V V+RVDK +G I
Sbjct: 19 VKQIFDYGSYVTLDEYGNLQAFLPWSEISSRWVKNIRDVIKEGRKIVVKVIRVDKRKGTI 78
Query: 301 DLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSIDLEELYVNIGWPLYRKHGHAFE 480
D+S ++V+E++ + ++ K + V I+ V++ ++ +E + + W L K+G A++
Sbjct: 79 DVSLKKVTEDEKRKKMSQWKKIQKVDKILEIVSQKINKTEKEGWEQVAWKLEDKYGDAYD 138
Query: 481 AFKVLLTGPDSVL 519
A + DS+L
Sbjct: 139 ALVKAVKEGDSIL 151
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 186,633,630,012
Number of Sequences: 518415
Number of Extensions: 186633630012
Number of Successful Extensions: 1140826441
Number of sequences better than 0.0: 0
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