BLASTX 7.6.2
Query= UN50431 /QuerySize=994
(993 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synapto... 73 2e-012
sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associa... 72 4e-012
sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associa... 72 4e-012
sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associate... 72 4e-012
sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizos... 72 4e-012
sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associa... 71 9e-012
sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associate... 70 2e-011
sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associa... 70 2e-011
sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associa... 70 2e-011
sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associa... 70 2e-011
sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associa... 70 3e-011
sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associa... 69 5e-011
sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associa... 69 5e-011
sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associate... 69 5e-011
sp|Q6Q595|SCS22_YEAST Vesicle-associated membrane protein-associ... 54 1e-006
>sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synaptobrevin-binding
protein OS=Aplysia californica PE=2 SV=1
Length = 260
Score = 73 bits (178), Expect = 2e-012
Identities = 40/95 (42%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E LI EL+F DLK++N TD + FKVKTT+PK+Y VRPN+G+++P
Sbjct: 5 EQALILEPAGELRFKGPFTDVVTADLKLSNPTDRRICFKVKTTAPKRYCVRPNSGILEPK 64
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPH 577
S + V LQ Y P+ + K KF++QS P H
Sbjct: 65 TSIAVAVMLQ-PFNYDPNEKNKHKFMVQSMYAPDH 98
>sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associated protein A
OS=Homo sapiens GN=VAPA PE=1 SV=3
Length = 249
Score = 72 bits (176), Expect = 4e-012
Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E L+ P +LKF +LK+ N +D V FKVKTT+P++Y VRPN+G+I P
Sbjct: 12 EQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPG 71
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHT 574
+ + V LQ +Y P+ + K KF++Q+ PP+T
Sbjct: 72 STVTVSVMLQ-PFDYDPNEKSKHKFMVQTIFAPPNT 106
>sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associated protein A
OS=Pongo abelii GN=VAPA PE=2 SV=2
Length = 249
Score = 72 bits (176), Expect = 4e-012
Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E L+ P +LKF +LK+ N +D V FKVKTT+P++Y VRPN+G+I P
Sbjct: 12 EQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPG 71
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHT 574
+ + V LQ +Y P+ + K KF++Q+ PP+T
Sbjct: 72 STVTVSVMLQ-PFDYDPNEKSKHKFMVQTIFAPPNT 106
>sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associated protein B
OS=Rattus norvegicus GN=Vapb PE=1 SV=3
Length = 243
Score = 72 bits (176), Expect = 4e-012
Identities = 42/95 (44%), Positives = 57/95 (60%), Gaps = 2/95 (2%)
Frame = -1
Query: 855 QLISIVPD-ELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWD 679
Q++S+ P ELKF +LK+ N TD V FKVKTT+P++Y VRPN+GVI
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAGA 65
Query: 678 SCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHT 574
S + V LQ +Y P+ + K KF++QS PP T
Sbjct: 66 SLNVSVMLQ-PFDYDPNEKSKHKFMVQSMFAPPDT 99
>sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizosaccharomyces
pombe GN=SPAC17C9.12 PE=1 SV=2
Length = 319
Score = 72 bits (176), Expect = 4e-012
Identities = 44/137 (32%), Positives = 74/137 (54%), Gaps = 9/137 (6%)
Frame = -1
Query: 792 CDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIRVTLQ-AQREYPPDMQCK 616
CDL++ N + FKVKTT+PK+Y VRPN G I+ + + V LQ E P +C+
Sbjct: 21 CDLELRNTAPYPIGFKVKTTAPKQYCVRPNGGRIEANSAVSVEVILQPLDHEPAPGTKCR 80
Query: 615 DKFLLQSTLVPPHTDVDDLPQDTFTKDSGKTLTECKLKVSYISSSTTT-------QRSSD 457
DKFL+QST + P D+ D +T+ S ++E K++ Y +T + +
Sbjct: 81 DKFLVQSTELKPELQGMDI-ADIWTQVSKANISERKIRCVYSEGPSTANAHANAHHQPAQ 139
Query: 456 SGATNVDANSSETISTV 406
+ T++ ++++ +TV
Sbjct: 140 TTTTSIPTSATDNYTTV 156
>sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associated protein B
OS=Mus musculus GN=Vapb PE=2 SV=3
Length = 243
Score = 71 bits (173), Expect = 9e-012
Identities = 42/95 (44%), Positives = 56/95 (58%), Gaps = 2/95 (2%)
Frame = -1
Query: 855 QLISIVPD-ELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWD 679
Q++S+ P ELKF +LK+ N TD V FKVKTT P++Y VRPN+GVI
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTVPRRYCVRPNSGVIDAGA 65
Query: 678 SCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHT 574
S + V LQ +Y P+ + K KF++QS PP T
Sbjct: 66 SLNVSVMLQ-PFDYDPNEKSKHKFMVQSMFAPPDT 99
>sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associated protein A
OS=Rattus norvegicus GN=Vapa PE=1 SV=3
Length = 249
Score = 70 bits (170), Expect = 2e-011
Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E L+ P +LKF +LK+ N +D V FKVKTT+P++Y VRPN+GVI P
Sbjct: 12 EQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGVIDPG 71
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPH 577
+ V LQ +Y P+ + K KF++Q+ PP+
Sbjct: 72 SIVTVSVMLQ-PFDYDPNEKSKHKFMVQTIFAPPN 105
>sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associated protein B
OS=Bos taurus GN=VAPB PE=2 SV=1
Length = 243
Score = 70 bits (170), Expect = 2e-011
Identities = 42/100 (42%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = -1
Query: 855 QLISIVPD-ELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWD 679
Q++S+ P ELKF +LK+ N TD V FKVKTT+P++Y VRPN+G+I
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 678 SCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHTDVDDL 559
S + V LQ +Y P+ + K KF++QS P TD D+
Sbjct: 66 SINVSVMLQ-PFDYDPNEKSKHKFMVQSMFAP--TDTSDM 102
>sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C
OS=Homo sapiens GN=VAPB PE=1 SV=3
Length = 243
Score = 70 bits (170), Expect = 2e-011
Identities = 42/100 (42%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = -1
Query: 855 QLISIVPD-ELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWD 679
Q++S+ P ELKF +LK+ N TD V FKVKTT+P++Y VRPN+G+I
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 678 SCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHTDVDDL 559
S + V LQ +Y P+ + K KF++QS P TD D+
Sbjct: 66 SINVSVMLQ-PFDYDPNEKSKHKFMVQSMFAP--TDTSDM 102
>sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associated protein
C16G5.05c OS=Schizosaccharomyces pombe GN=SPBC16G5.05c PE=1 SV=1
Length = 383
Score = 70 bits (170), Expect = 2e-011
Identities = 43/124 (34%), Positives = 72/124 (58%), Gaps = 6/124 (4%)
Frame = -1
Query: 786 LKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIRVTLQAQREYP-PDMQCKDK 610
+ V N V FKVKTT+PK Y VRPN+G I+P + ++V LQA +E P PD +C+DK
Sbjct: 23 ISVHNPNPEPVIFKVKTTAPKHYCVRPNSGKIEPKSTVNVQVLLQAMKEEPAPDFKCRDK 82
Query: 609 FLLQSTLV--PPHTDVDDLPQD-TFTKDSGKTLTECKLKVSYISSSTTTQRSSDSGATNV 439
FL+QS + ++V++ + T + G+++ + K++ Y S+ +S+D N
Sbjct: 83 FLIQSMAIGDADTSNVENYHEFWTEMEKQGRSIFDRKIRCVY--STKQPPQSADKQVENT 140
Query: 438 DANS 427
++
Sbjct: 141 STSN 144
>sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associated protein A
OS=Mus musculus GN=Vapa PE=1 SV=2
Length = 249
Score = 70 bits (169), Expect = 3e-011
Identities = 37/95 (38%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E L+ P +LKF +LK+ N +D V FKVKTT+P++Y VRPN+G+I P
Sbjct: 12 EQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPG 71
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPH 577
+ V LQ +Y P+ + K KF++Q+ PP+
Sbjct: 72 SIVTVSVMLQ-PFDYDPNEKSKHKFMVQTIFAPPN 105
>sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associated protein
SCS2 OS=Saccharomyces cerevisiae GN=SCS2 PE=1 SV=3
Length = 244
Score = 69 bits (167), Expect = 5e-011
Identities = 53/175 (30%), Positives = 85/175 (48%), Gaps = 11/175 (6%)
Frame = -1
Query: 849 ISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWDSCI 670
+ I PD L + L +QS ++N +D +AFKVKTT+PK Y VRPN V+ P ++
Sbjct: 4 VEISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQ 63
Query: 669 IRVTLQAQREYP-PDMQCKDKFLLQSTLVPPH----TDVDDLPQDTFTKDSGKTLTECKL 505
++V E P D +C+DKFL+ TL P+ V D+ D + + +++ K+
Sbjct: 64 VQVIFLGLTEEPAADFKCRDKFLV-ITLPSPYDLNGKAVADVWSDLEAEFKQQAISK-KI 121
Query: 504 KVSYISSSTTTQRSSDSGATNVDANSSETISTVQRLKEERDAAVKQTQQLQHELE 340
KV Y+ S + N+ N VQ + + AV +++ E E
Sbjct: 122 KVKYLISPDVHPAQNQ----NIQENKETVEPVVQDSEPKEVPAVVNEKEVPAEPE 172
>sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associated protein A
OS=Bos taurus GN=VAPA PE=2 SV=1
Length = 249
Score = 69 bits (167), Expect = 5e-011
Identities = 37/95 (38%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
Frame = -1
Query: 861 ENQLISIVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPW 682
E L+ P +LKF +LK+ N +D V FKVKTT+P++Y VRPN+G+I P
Sbjct: 12 EQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPG 71
Query: 681 DSCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPH 577
+ + V LQ +Y P+ + K KF++Q+ PP+
Sbjct: 72 LTVTVSVMLQ-PFDYDPNEKSKHKFMVQTIFAPPN 105
>sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associated protein B
OS=Sus scrofa GN=VAPB PE=3 SV=1
Length = 243
Score = 69 bits (167), Expect = 5e-011
Identities = 40/95 (42%), Positives = 56/95 (58%), Gaps = 2/95 (2%)
Frame = -1
Query: 855 QLISIVPD-ELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWD 679
Q++S+ P ELKF +LK+ N TD V FKVKTT+P++Y VRPN+G+I
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 678 SCIIRVTLQAQREYPPDMQCKDKFLLQSTLVPPHT 574
S + V LQ +Y P+ + K KF++QS P T
Sbjct: 66 SINVSVMLQ-PFDYDPNEKSKHKFMVQSMFAPADT 99
>sp|Q6Q595|SCS22_YEAST Vesicle-associated membrane protein-associated protein
SCS22 OS=Saccharomyces cerevisiae GN=SCS22 PE=1 SV=2
Length = 175
Score = 54 bits (129), Expect = 1e-006
Identities = 34/98 (34%), Positives = 55/98 (56%), Gaps = 4/98 (4%)
Frame = -1
Query: 843 IVPDELKFLFELEKQSYCDLKVANKTDNYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIR 664
IVP++L F L KQS +K+ N + V FKV+T++P KY VRPN +I +S ++
Sbjct: 3 IVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQ 62
Query: 663 VTLQAQREYPPD---MQCKDKFLLQSTLVP-PHTDVDD 562
+ + D Q +DKFL+ + +P + +V+D
Sbjct: 63 IVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVED 100
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 187,698,552,422
Number of Sequences: 518415
Number of Extensions: 187698552422
Number of Successful Extensions: 1153387334
Number of sequences better than 0.0: 0
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