BLASTX 7.6.2
Query= UN51256 /QuerySize=1233
(1232 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54RS7|ELMOC_DICDI ELMO domain-containing protein C OS=Dictyo... 102 5e-021
sp|Q54YW1|ELMOA_DICDI ELMO domain-containing protein A OS=Dictyo... 96 5e-019
sp|Q8IZ81|ELMD2_HUMAN ELMO domain-containing protein 2 OS=Homo s... 94 1e-018
sp|Q8BGF6|ELMD2_MOUSE ELMO domain-containing protein 2 OS=Mus mu... 92 7e-018
sp|Q08DZ3|ELMD2_BOVIN ELMO domain-containing protein 2 OS=Bos ta... 90 3e-017
sp|Q54UP9|ELMOD_DICDI Ankyrin repeat and ELMO domain-containing ... 85 8e-016
sp|Q54VR8|ELMOB_DICDI ELMO domain-containing protein B OS=Dictyo... 82 5e-015
sp|Q8N336|ELMD1_HUMAN ELMO domain-containing protein 1 OS=Homo s... 77 2e-013
sp|Q0IIE6|ELMD1_BOVIN ELMO domain-containing protein 1 OS=Bos ta... 76 4e-013
sp|Q3V1U8|ELMD1_MOUSE ELMO domain-containing protein 1 OS=Mus mu... 76 5e-013
sp|Q5NVD7|ELMD1_PONAB ELMO domain-containing protein 1 OS=Pongo ... 76 5e-013
sp|Q92556|ELMO1_HUMAN Engulfment and cell motility protein 1 OS=... 56 5e-007
sp|Q8BPU7|ELMO1_MOUSE Engulfment and cell motility protein 1 OS=... 56 5e-007
>sp|Q54RS7|ELMOC_DICDI ELMO domain-containing protein C OS=Dictyostelium
discoideum GN=elmoC PE=4 SV=1
Length = 618
Score = 102 bits (254), Expect = 5e-021
Identities = 67/203 (33%), Positives = 107/203 (52%), Gaps = 18/203 (8%)
Frame = +2
Query: 260 GTHGDSRPSFDLTPAQEECLHKLQSRIDVAYDSSIPQHQEALKDLWKLAFPKEELHGIVS 439
G+H D S +T Q + + L + Y+S+ P H+E LK LW L +P++E S
Sbjct: 348 GSHIDR--SKKVTAKQSQTIKILFQKKSTIYESTNPDHEEYLKHLWSLLYPEQEFQK-KS 404
Query: 440 EQWKEMGWQGKDPSTDFRGGGFISLENLLYFAKNFPKSFQDLLRKQVGDRSVWEYPFAVV 619
WK+ G+Q DP+ DFRG G + L NL++ ++ Q++L + DR +YPFAV
Sbjct: 405 PLWKKFGFQSDDPTRDFRGMGIMGLLNLIHLVQHHNDWVQEILAQ---DR---DYPFAVA 458
Query: 620 GINITFMLIQML-----GLEAVKPRSIVGETFLRFLSV----NESAFDLLYCIAFKLMDQ 772
GINI+ ++ ++ L+ S +++ L N+ AF+ LY + F L+D
Sbjct: 459 GINISNLIFEVFQISEDSLQQPWYSSFWSSSYMAMLCSMSRHNDHAFEELYFLIFNLLDH 518
Query: 773 QLLSMRASYMEFNTVMKSTRRQL 841
+ M A+YM F V+K + QL
Sbjct: 519 LWIQMNATYMMFPLVIKKLKSQL 541
>sp|Q54YW1|ELMOA_DICDI ELMO domain-containing protein A OS=Dictyostelium
discoideum GN=elmoA PE=1 SV=1
Length = 977
Score = 96 bits (237), Expect = 5e-019
Identities = 46/106 (43%), Positives = 66/106 (62%), Gaps = 1/106 (0%)
Frame = +2
Query: 326 LQSRIDVAYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGF 505
+ +R +V ++ +H L LW L +P +L VSEQWK+MG+QG DP TDFR G
Sbjct: 369 ITNRKNVTFNKESSEHDALLMKLWSLTYPGVKLESRVSEQWKQMGFQGTDPCTDFRAMGI 428
Query: 506 ISLENLLYFAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFML 643
L+NL+YFA+N+ + F+ ++ Q+ DR EYP A GI +TF L
Sbjct: 429 WGLDNLIYFAQNYNEKFRKIVNSQI-DRKEREYPTATAGIVLTFEL 473
>sp|Q8IZ81|ELMD2_HUMAN ELMO domain-containing protein 2 OS=Homo sapiens
GN=ELMOD2 PE=1 SV=1
Length = 293
Score = 94 bits (233), Expect = 1e-018
Identities = 46/108 (42%), Positives = 67/108 (62%), Gaps = 2/108 (1%)
Frame = +2
Query: 350 YDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLLY 529
YDS QH+E L LW L P ++L+ +S+QW E+G+QG DP TDFRG G + L NL+Y
Sbjct: 120 YDSDNLQHEELLMKLWNLLMPTKKLNARISKQWAEIGFQGDDPKTDFRGMGILGLINLVY 179
Query: 530 FAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFMLIQMLGLEAVK 673
F++N+ +L + + Y +A+VGIN+T M +L EA+K
Sbjct: 180 FSENYTSEAHQILSR--SNHPKLGYSYAIVGINLTEMAYSLLKSEALK 225
>sp|Q8BGF6|ELMD2_MOUSE ELMO domain-containing protein 2 OS=Mus musculus
GN=Elmod2 PE=2 SV=1
Length = 293
Score = 92 bits (227), Expect = 7e-018
Identities = 45/122 (36%), Positives = 73/122 (59%), Gaps = 2/122 (1%)
Frame = +2
Query: 308 EECLHKLQSRIDVAYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTD 487
++ H +++ YDS+ QH++ L LW L P ++L +S+QW ++G+QG DP TD
Sbjct: 106 KQLYHDVENVRKKPYDSANAQHEKMLLKLWSLLMPTKKLTARISKQWADIGFQGDDPKTD 165
Query: 488 FRGGGFISLENLLYFAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFMLIQMLGLEA 667
FRG G + L NL+YF++N+ +L + + Y +A+VGIN+T M +L EA
Sbjct: 166 FRGMGILGLINLVYFSENYTSEAHQILSR--SNHPKLGYSYAIVGINLTEMAYSLLKSEA 223
Query: 668 VK 673
+K
Sbjct: 224 LK 225
>sp|Q08DZ3|ELMD2_BOVIN ELMO domain-containing protein 2 OS=Bos taurus GN=ELMOD2
PE=2 SV=1
Length = 293
Score = 90 bits (222), Expect = 3e-017
Identities = 44/108 (40%), Positives = 66/108 (61%), Gaps = 2/108 (1%)
Frame = +2
Query: 350 YDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLLY 529
YDS QH++ L LW L P ++L +S+QW ++G+QG DP TDFRG G + L NL+Y
Sbjct: 120 YDSDNLQHEKLLIKLWNLLMPTKKLKARISKQWADIGFQGDDPKTDFRGMGILGLINLVY 179
Query: 530 FAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFMLIQMLGLEAVK 673
F++N+ +L + + Y +A+VGIN+T M +L EA+K
Sbjct: 180 FSENYTSEAHQILSR--SNHPKLGYSYAIVGINLTEMAYSLLKSEALK 225
>sp|Q54UP9|ELMOD_DICDI Ankyrin repeat and ELMO domain-containing protein D
OS=Dictyostelium discoideum GN=elmoD PE=4 SV=1
Length = 1267
Score = 85 bits (209), Expect = 8e-016
Identities = 55/178 (30%), Positives = 87/178 (48%), Gaps = 19/178 (10%)
Frame = +2
Query: 320 HKLQSRI---DVAYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDF 490
HK+Q I Y+ P HQ L+ LW FP + E W+ +G+Q KDPS+DF
Sbjct: 288 HKIQGLIMDSKTPYNKDEPSHQRLLETLWSTLFPNQVFQR-SHENWQIIGFQNKDPSSDF 346
Query: 491 RGGGFISLENLLYFAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFMLIQMLGLEAV 670
RG G L++L+Y A+N F + L + + + YP+A GI +T L+ E V
Sbjct: 347 RGMGLAGLKHLIYLAQNHKDMFMNPLINRQPEANY--YPYATSGIQVTSFLV-----ECV 399
Query: 671 KP-------RSIVGETFLRFLSVNESAFDLLYCIAFKLMDQQLLSMRASYMEFNTVMK 823
KP ++G+ + L +E+A + +YC+ ++ A+YM F V +
Sbjct: 400 KPINISANHSDVIGQIY-PILFESENALNEIYCVLMEIFGIVWKDWNATYMIFQKVFQ 456
>sp|Q54VR8|ELMOB_DICDI ELMO domain-containing protein B OS=Dictyostelium
discoideum GN=elmoB PE=4 SV=1
Length = 284
Score = 82 bits (202), Expect = 5e-015
Identities = 36/110 (32%), Positives = 68/110 (61%), Gaps = 3/110 (2%)
Frame = +2
Query: 326 LQSRIDVAYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGF 505
++ + + YD++ +H+ +L+ LW+ P +S++W +G+QG DP+TDFRG G
Sbjct: 110 IEKKQKIPYDNNNLEHEASLERLWEALLPDVRRSARLSKEWGTLGFQGMDPATDFRGMGI 169
Query: 506 ISLENLLYFAKNFPKSFQDLLRKQVGDRSVWEYPFAVVGINITFMLIQML 655
+ L+NL+YF+ + +++L+ S YPFA+ GINIT +++ ++
Sbjct: 170 LGLDNLIYFSTQHSEDAREILK---NSNSKCCYPFAITGINITALVLNLI 216
>sp|Q8N336|ELMD1_HUMAN ELMO domain-containing protein 1 OS=Homo sapiens
GN=ELMOD1 PE=2 SV=3
Length = 334
Score = 77 bits (189), Expect = 2e-013
Identities = 37/74 (50%), Positives = 46/74 (62%)
Frame = +2
Query: 347 AYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLL 526
AYDS PQH+E L LWK P L +S+QW E+G+QG DP TDFRG G + L NL
Sbjct: 126 AYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQ 185
Query: 527 YFAKNFPKSFQDLL 568
YFA+ + Q +L
Sbjct: 186 YFAERDATAAQQVL 199
>sp|Q0IIE6|ELMD1_BOVIN ELMO domain-containing protein 1 OS=Bos taurus GN=ELMOD1
PE=2 SV=1
Length = 326
Score = 76 bits (186), Expect = 4e-013
Identities = 36/74 (48%), Positives = 46/74 (62%)
Frame = +2
Query: 347 AYDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLL 526
+YDS PQH+E L LWK P L +S+QW E+G+QG DP TDFRG G + L NL
Sbjct: 126 SYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQ 185
Query: 527 YFAKNFPKSFQDLL 568
YFA+ + Q +L
Sbjct: 186 YFAERDAAAAQQVL 199
>sp|Q3V1U8|ELMD1_MOUSE ELMO domain-containing protein 1 OS=Mus musculus
GN=Elmod1 PE=2 SV=2
Length = 326
Score = 76 bits (185), Expect = 5e-013
Identities = 38/77 (49%), Positives = 46/77 (59%)
Frame = +2
Query: 350 YDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLLY 529
YDS PQH+E L LW+L P L VS+QW E+G+QG DP TDFRG G + L NL Y
Sbjct: 127 YDSDNPQHEEMLLKLWELLKPNTPLESRVSKQWCEIGFQGDDPKTDFRGMGLLGLYNLQY 186
Query: 530 FAKNFPKSFQDLLRKQV 580
FA+ Q +L V
Sbjct: 187 FAERDATVAQQVLSDSV 203
>sp|Q5NVD7|ELMD1_PONAB ELMO domain-containing protein 1 OS=Pongo abelii
GN=ELMOD1 PE=2 SV=1
Length = 326
Score = 76 bits (185), Expect = 5e-013
Identities = 36/73 (49%), Positives = 45/73 (61%)
Frame = +2
Query: 350 YDSSIPQHQEALKDLWKLAFPKEELHGIVSEQWKEMGWQGKDPSTDFRGGGFISLENLLY 529
YDS PQH+E L LWK P L +S+QW E+G+QG DP TDFRG G + L NL Y
Sbjct: 127 YDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQY 186
Query: 530 FAKNFPKSFQDLL 568
FA+ + Q +L
Sbjct: 187 FAERDATAAQQVL 199
>sp|Q92556|ELMO1_HUMAN Engulfment and cell motility protein 1 OS=Homo sapiens
GN=ELMO1 PE=1 SV=2
Length = 727
Score = 56 bits (133), Expect = 5e-007
Identities = 36/149 (24%), Positives = 76/149 (51%), Gaps = 5/149 (3%)
Frame = +2
Query: 416 EELHGIVSEQWKEMGW-QGKDPSTDF--RGGGFISLENLLYFAKNFPKSFQDLLRKQVGD 586
E+ + + +K++G+ +P+ DF G ++L+N+LYFAK+ ++ ++ +
Sbjct: 346 EKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSR 405
Query: 587 RSVWEYPFAVVGINITFMLIQMLGLEAVKPRSIVGETFLRFLSVNESAFDLLYCIAFKLM 766
E PF I +T ML ++L + + + F ++ +F+ +CI +L+
Sbjct: 406 EDKHECPFGRSSIELTKMLCEILKVGELPSETC--NDFHPMFFTHDRSFEEFFCICIQLL 463
Query: 767 DQQLLSMRASYMEFNTVMKSTRRQLEREI 853
++ MRA+ +FN VM+ + Q+ R +
Sbjct: 464 NKTWKEMRATSEDFNKVMQVVKEQVMRAL 492
>sp|Q8BPU7|ELMO1_MOUSE Engulfment and cell motility protein 1 OS=Mus musculus
GN=Elmo1 PE=1 SV=2
Length = 727
Score = 56 bits (133), Expect = 5e-007
Identities = 36/149 (24%), Positives = 76/149 (51%), Gaps = 5/149 (3%)
Frame = +2
Query: 416 EELHGIVSEQWKEMGW-QGKDPSTDF--RGGGFISLENLLYFAKNFPKSFQDLLRKQVGD 586
E+ + + +K++G+ +P+ DF G ++L+N+LYFAK+ ++ ++ +
Sbjct: 346 EKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSR 405
Query: 587 RSVWEYPFAVVGINITFMLIQMLGLEAVKPRSIVGETFLRFLSVNESAFDLLYCIAFKLM 766
E PF I +T ML ++L + + + F ++ +F+ +CI +L+
Sbjct: 406 EDKHECPFGRSSIELTKMLCEILKVGELPSETC--NDFHPMFFTHDRSFEEFFCICIQLL 463
Query: 767 DQQLLSMRASYMEFNTVMKSTRRQLEREI 853
++ MRA+ +FN VM+ + Q+ R +
Sbjct: 464 NKTWKEMRATSEDFNKVMQVVKEQVMRAL 492
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 191,186,815,274
Number of Sequences: 518415
Number of Extensions: 191186815274
Number of Successful Extensions: 1167985300
Number of sequences better than 0.0: 0
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