BLASTX 7.6.2
Query= UN51466 /QuerySize=913
(912 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O34990|PURU_BACSU Formyltetrahydrofolate deformylase OS=Bacil... 170 2e-041
sp|Q55135|PURU_SYNY3 Formyltetrahydrofolate deformylase OS=Synec... 169 3e-041
sp|Q46339|PURU_CORS1 Formyltetrahydrofolate deformylase OS=Coryn... 148 9e-035
sp|P0A5T7|PURU_MYCBO Formyltetrahydrofolate deformylase OS=Mycob... 145 4e-034
sp|P0A5T6|PURU_MYCTU Formyltetrahydrofolate deformylase OS=Mycob... 145 4e-034
sp|Q03432|PURU_HAEIN Formyltetrahydrofolate deformylase OS=Haemo... 135 5e-031
sp|P0A440|PURU_ECOL6 Formyltetrahydrofolate deformylase OS=Esche... 125 5e-028
sp|P0A441|PURU_SHIFL Formyltetrahydrofolate deformylase OS=Shige... 125 5e-028
sp|P37051|PURU_ECOLI Formyltetrahydrofolate deformylase OS=Esche... 125 6e-028
sp|P12040|PUR3_BACSU Phosphoribosylglycinamide formyltransferase... 90 2e-017
sp|Q64737|PUR2_MOUSE Trifunctional purine biosynthetic protein a... 86 3e-016
sp|P43846|PUR3_HAEIN Phosphoribosylglycinamide formyltransferase... 83 2e-015
sp|P21872|PUR2_CHICK Trifunctional purine biosynthetic protein a... 82 4e-015
sp|Q59A32|PUR2_BOVIN Trifunctional purine biosynthetic protein a... 82 5e-015
sp|P22102|PUR2_HUMAN Trifunctional purine biosynthetic protein a... 80 2e-014
sp|P08179|PUR3_ECOLI Phosphoribosylglycinamide formyltransferase... 71 8e-012
sp|P16340|PUR2_DROPS Trifunctional purine biosynthetic protein a... 70 2e-011
sp|Q5HH12|PUR3_STAAC Phosphoribosylglycinamide formyltransferase... 69 4e-011
sp|Q6GI12|PUR3_STAAR Phosphoribosylglycinamide formyltransferase... 68 7e-011
sp|Q6GAE1|PUR3_STAAS Phosphoribosylglycinamide formyltransferase... 68 9e-011
>sp|O34990|PURU_BACSU Formyltetrahydrofolate deformylase OS=Bacillus subtilis
GN=purU PE=3 SV=2
Length = 300
Score = 170 bits (429), Expect = 2e-041
Identities = 92/225 (40%), Positives = 142/225 (63%), Gaps = 13/225 (5%)
Frame = -1
Query: 840 FSNYCKKFNAMRSVVRVPSLDPKYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNH 661
F++ +KF+ S+ L ++A+ +SK+ HCL E++ +WQ G L +I VISNH
Sbjct: 84 FASVAEKFDMTWSLTLASELK---RVAIFVSKELHCLHELIWEWQTGNLMAEIAVVISNH 140
Query: 660 ERAPNTHIMRFLQRHGISYHYLPTTD--QNKIEEEIFELVK--DTDFIVLARYMQVLSGN 493
E A ++R I +HY+ + ++E++ EL++ D D IVLARYMQ+L+ +
Sbjct: 141 EEA-----RELVERLNIPFHYMKANKDIRAEVEKKQLELLEQYDVDVIVLARYMQILTPD 195
Query: 492 FLKGYGKDVINIHHGLLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVER 313
F+ + +INIHH LP+F G +P K+A++ GVKLIGAT+H+VT +LD GPIIEQ +ER
Sbjct: 196 FVSAHPNRIINIHHSFLPAFIGANPYKRAYERGVKLIGATSHYVTNDLDEGPIIEQDIER 255
Query: 312 VSHRDNLTSFVQKSEDLEKKCLMKAIKSYCELRVLPYGTHKTVVF 178
V HRDN + +E+ L +A+K + E RV+ + +KT+VF
Sbjct: 256 VDHRDNAEALKNIGRTIERSVLARAVKWHLEDRVIVH-ENKTIVF 299
>sp|Q55135|PURU_SYNY3 Formyltetrahydrofolate deformylase OS=Synechocystis sp.
(strain PCC 6803) GN=purU PE=3 SV=1
Length = 284
Score = 169 bits (427), Expect = 3e-041
Identities = 86/201 (42%), Positives = 132/201 (65%), Gaps = 11/201 (5%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPT 589
++AL +SKQDHCL+++L +W+ G+L +I +ISNH + + GI +H LP
Sbjct: 90 RLALWVSKQDHCLLDILWRWRSGELRCEIPLIISNH-----PDLKSIADQFGIDFHCLPI 144
Query: 588 TDQNKIEEEIFELV----KDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRS 421
T +NK+ +E EL D +VLA+Y+Q+L+ +F+ + ++INIHH LP+F G +
Sbjct: 145 TKENKLAQETAELALLKQYQIDLVVLAKYLQILTTDFVVQF-PNIINIHHSFLPAFPGAN 203
Query: 420 PAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCLMK 241
P +A + GVK+IGAT H+ T +LD GPIIEQ V RVSHRDN+ ++K DLE+ L +
Sbjct: 204 PYHRAHERGVKIIGATAHYATAQLDEGPIIEQDVVRVSHRDNVDDLIRKGRDLERVVLAR 263
Query: 240 AIKSYCELRVLPYGTHKTVVF 178
A++ + + R+L Y ++TVVF
Sbjct: 264 AVRLHLQHRILVY-DNRTVVF 283
>sp|Q46339|PURU_CORS1 Formyltetrahydrofolate deformylase OS=Corynebacterium sp.
(strain P-1) GN=purU PE=3 SV=1
Length = 286
Score = 148 bits (371), Expect = 9e-035
Identities = 83/202 (41%), Positives = 117/202 (57%), Gaps = 10/202 (4%)
Frame = -1
Query: 774 KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYL 595
K K+ +++SK +HCL ++L + G LP+++ V SNH P+ + ++ +GI +H++
Sbjct: 89 KTKVLIMVSKFEHCLQDLLFRMHSGDLPIEVVGVASNH---PDHRSL--VEWYGIGFHHI 143
Query: 594 PTTDQNK--IEEEIFELVKDT--DFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKG 427
P + K E + EL+ T + +VLARYMQVLS + INIHH LPSFKG
Sbjct: 144 PISKDTKPRAEAALLELIDQTGAELVVLARYMQVLSDHLASELTGKTINIHHSFLPSFKG 203
Query: 426 RSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCL 247
P QA++ GVK +GAT H+V ELD GPII Q V V H V D E K L
Sbjct: 204 AKPYHQAWERGVKTVGATAHYVNSELDEGPIIAQQVVEVDHTYGPQDLVAAGRDSECKAL 263
Query: 246 MKAIKSYCELRVLPYGTHKTVV 181
A++ +CE RV YG ++TVV
Sbjct: 264 SNAVRWHCEGRVFLYG-NRTVV 284
>sp|P0A5T7|PURU_MYCBO Formyltetrahydrofolate deformylase OS=Mycobacterium bovis
GN=purU PE=3 SV=1
Length = 310
Score = 145 bits (365), Expect = 4e-034
Identities = 77/190 (40%), Positives = 118/190 (62%), Gaps = 8/190 (4%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPT 589
++A++ S +DHCL+++L + + G+L + + VI+NH H+ F G+ + ++P
Sbjct: 117 RVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLA-AHVRPF----GVPFIHIPA 171
Query: 588 TDQNKIEEE---IFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRSP 418
T + E E + L + D +VLARYMQ+LS FL+ G +INIHH LP+F G +P
Sbjct: 172 TRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAP 231
Query: 417 AKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCLMKA 238
++A + GVKLIGAT H+VTE LD GPIIEQ V RV H + V+ D+E+ L +A
Sbjct: 232 YQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRA 291
Query: 237 IKSYCELRVL 208
+ +C+ RV+
Sbjct: 292 VLWHCQDRVI 301
>sp|P0A5T6|PURU_MYCTU Formyltetrahydrofolate deformylase OS=Mycobacterium
tuberculosis GN=purU PE=3 SV=1
Length = 310
Score = 145 bits (365), Expect = 4e-034
Identities = 77/190 (40%), Positives = 118/190 (62%), Gaps = 8/190 (4%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPT 589
++A++ S +DHCL+++L + + G+L + + VI+NH H+ F G+ + ++P
Sbjct: 117 RVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLA-AHVRPF----GVPFIHIPA 171
Query: 588 TDQNKIEEE---IFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRSP 418
T + E E + L + D +VLARYMQ+LS FL+ G +INIHH LP+F G +P
Sbjct: 172 TRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAP 231
Query: 417 AKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCLMKA 238
++A + GVKLIGAT H+VTE LD GPIIEQ V RV H + V+ D+E+ L +A
Sbjct: 232 YQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRA 291
Query: 237 IKSYCELRVL 208
+ +C+ RV+
Sbjct: 292 VLWHCQDRVI 301
>sp|Q03432|PURU_HAEIN Formyltetrahydrofolate deformylase OS=Haemophilus
influenzae GN=purU PE=3 SV=2
Length = 278
Score = 135 bits (339), Expect = 5e-031
Identities = 77/200 (38%), Positives = 117/200 (58%), Gaps = 10/200 (5%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPT 589
+I +L++K+ HCL ++L K G L V+I VI NH+ ++ ++R I +H +
Sbjct: 84 RIVILVTKEAHCLGDILMKNYYGALDVEIAAVIGNHD-----NLRELVERFNIPFHLVSH 138
Query: 588 TDQNKIEEE--IFELVKD--TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRS 421
+ ++E + + E + + D+IVLA+YM+VL+ F+ Y VINIHH LP+F G
Sbjct: 139 ENLTRVEHDKLLAEKIDEYTPDYIVLAKYMRVLNPEFVARYPNRVINIHHSFLPAFIGAK 198
Query: 420 PAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCLMK 241
P +QA+ GVK+IGAT HF+ ELD GPII Q V V H N + ++ D+EK L +
Sbjct: 199 PYQQAYKRGVKIIGATAHFINNELDQGPIIMQNVINVDHTYNAEAMMRAGRDVEKTVLSR 258
Query: 240 AIKSYCELRVLPYGTHKTVV 181
A+ R+ Y +KTVV
Sbjct: 259 ALDLALHDRIFVY-KNKTVV 277
>sp|P0A440|PURU_ECOL6 Formyltetrahydrofolate deformylase OS=Escherichia coli O6
GN=purU PE=3 SV=1
Length = 280
Score = 125 bits (313), Expect = 5e-028
Identities = 72/210 (34%), Positives = 119/210 (56%), Gaps = 12/210 (5%)
Frame = -1
Query: 792 VPSLDP--KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQR 619
V L+P + +I +L++K+ HCL ++L K G L V+I VI NH+ + ++R
Sbjct: 76 VRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDT-----LRSLVER 130
Query: 618 HGISYHYL--PTTDQNKIEEEIFELVK--DTDFIVLARYMQVLSGNFLKGYGKDVINIHH 451
I + + +N+ ++++ + + D++VLA+YM+VL+ F+ + +INIHH
Sbjct: 131 FDIPFELVSHEGLSRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHH 190
Query: 450 GLLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKS 271
LP+F G P QA++ GVK+IGAT H+V + LD GPII Q V V H ++
Sbjct: 191 SFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAG 250
Query: 270 EDLEKKCLMKAIKSYCELRVLPYGTHKTVV 181
D+EK L +A+ RV YG ++T++
Sbjct: 251 RDVEKNVLSRALYKVLAQRVFVYG-NRTII 279
>sp|P0A441|PURU_SHIFL Formyltetrahydrofolate deformylase OS=Shigella flexneri
GN=purU PE=3 SV=1
Length = 280
Score = 125 bits (313), Expect = 5e-028
Identities = 72/210 (34%), Positives = 119/210 (56%), Gaps = 12/210 (5%)
Frame = -1
Query: 792 VPSLDP--KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQR 619
V L+P + +I +L++K+ HCL ++L K G L V+I VI NH+ + ++R
Sbjct: 76 VRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDT-----LRSLVER 130
Query: 618 HGISYHYL--PTTDQNKIEEEIFELVK--DTDFIVLARYMQVLSGNFLKGYGKDVINIHH 451
I + + +N+ ++++ + + D++VLA+YM+VL+ F+ + +INIHH
Sbjct: 131 FDIPFELVSHEGLSRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHH 190
Query: 450 GLLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKS 271
LP+F G P QA++ GVK+IGAT H+V + LD GPII Q V V H ++
Sbjct: 191 SFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAG 250
Query: 270 EDLEKKCLMKAIKSYCELRVLPYGTHKTVV 181
D+EK L +A+ RV YG ++T++
Sbjct: 251 RDVEKNVLSRALYKVLAQRVFVYG-NRTII 279
>sp|P37051|PURU_ECOLI Formyltetrahydrofolate deformylase OS=Escherichia coli
(strain K12) GN=purU PE=1 SV=1
Length = 280
Score = 125 bits (312), Expect = 6e-028
Identities = 72/210 (34%), Positives = 119/210 (56%), Gaps = 12/210 (5%)
Frame = -1
Query: 792 VPSLDP--KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQR 619
V L+P + +I +L++K+ HCL ++L K G L V+I VI NH+ + ++R
Sbjct: 76 VRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDT-----LRSLVER 130
Query: 618 HGISYHYL--PTTDQNKIEEEIFELVK--DTDFIVLARYMQVLSGNFLKGYGKDVINIHH 451
I + + +N+ ++++ + + D++VLA+YM+VL+ F+ + +INIHH
Sbjct: 131 FDIPFELVSHEGLTRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHH 190
Query: 450 GLLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKS 271
LP+F G P QA++ GVK+IGAT H+V + LD GPII Q V V H ++
Sbjct: 191 SFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAG 250
Query: 270 EDLEKKCLMKAIKSYCELRVLPYGTHKTVV 181
D+EK L +A+ RV YG ++T++
Sbjct: 251 RDVEKNVLSRALYKVLAQRVFVYG-NRTII 279
>sp|P12040|PUR3_BACSU Phosphoribosylglycinamide formyltransferase OS=Bacillus
subtilis GN=purN PE=3 SV=2
Length = 195
Score = 90 bits (222), Expect = 2e-017
Identities = 51/133 (38%), Positives = 73/133 (54%), Gaps = 4/133 (3%)
Frame = -1
Query: 618 HGISYHYLPTTDQNK--IEEEIFELVK--DTDFIVLARYMQVLSGNFLKGYGKDVINIHH 451
H S+ + P + +NK E+ I E ++ + + I LA YM+++ L+ YG +INIH
Sbjct: 51 HIPSFAFEPKSYENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYGGKIINIHP 110
Query: 450 GLLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKS 271
LLP+F G QAF AGVK+ G T H+V E +D+GPII Q + D L + Q+
Sbjct: 111 SLLPAFPGIDAVGQAFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEHDTLETIEQRI 170
Query: 270 EDLEKKCLMKAIK 232
LE K IK
Sbjct: 171 HKLEHKWYPSVIK 183
>sp|Q64737|PUR2_MOUSE Trifunctional purine biosynthetic protein adenosine-3
OS=Mus musculus GN=Gart PE=2 SV=2
Length = 1010
Score = 86 bits (211), Expect = 3e-016
Identities = 58/192 (30%), Positives = 96/192 (50%), Gaps = 10/192 (5%)
Frame = -1
Query: 789 PSLDPKYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNH------ERAPNTHIMRF 628
P K ++A+L+S L ++ +D K I VISN +RA I
Sbjct: 802 PVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERAGIPTR 861
Query: 627 LQRHGISYHYLPTTDQNKIEEEIFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHG 448
+ H +S + + N ++ + E D + LA +M++LSG F++ + ++NIH
Sbjct: 862 VINHKLSKNRVEF--DNAVDHVLEEF--SVDIVCLAGFMRILSGPFVRKWDGKMLNIHPS 917
Query: 447 LLPSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSE 268
LLPSFKG + +Q +AGV + G T HFV E++D+G II Q V D + + ++ +
Sbjct: 918 LLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVK 977
Query: 267 DLEKKCLMKAIK 232
E K A++
Sbjct: 978 VAEHKIFPAALQ 989
>sp|P43846|PUR3_HAEIN Phosphoribosylglycinamide formyltransferase OS=Haemophilus
influenzae GN=purN PE=3 SV=1
Length = 212
Score = 83 bits (204), Expect = 2e-015
Identities = 58/190 (30%), Positives = 95/190 (50%), Gaps = 6/190 (3%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPT 589
KIA+L+S Q L ++ G +P I CVISN +A ++R Q +L
Sbjct: 3 KIAVLISGQGTNLQTIIDACHSGDIPAKIACVISN--KADAYGLVRAKQAQIPQAVFLRK 60
Query: 588 TDQNKIE--EEIFELVKD--TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRS 421
N +E + I + ++ D IVLA YM++L+ F + + ++NIH LLP + G +
Sbjct: 61 NFSNNLEMDDAIGDYLQSLAVDLIVLAGYMKILTPKFTQRFAGKILNIHPSLLPKYAGLN 120
Query: 420 PAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKCLMK 241
++A +AG G T HFV EE+D G I+ Q + D++ ++ + E +
Sbjct: 121 TYQRAIEAGDNEHGTTVHFVNEEVDGGAIVLQAKVPIFPEDSIEEVEARTREQEYQIYPL 180
Query: 240 AIKSYCELRV 211
IK + E R+
Sbjct: 181 VIKWFTEGRL 190
>sp|P21872|PUR2_CHICK Trifunctional purine biosynthetic protein adenosine-3
OS=Gallus gallus GN=GART PE=2 SV=1
Length = 1003
Score = 82 bits (202), Expect = 4e-015
Identities = 56/187 (29%), Positives = 94/187 (50%), Gaps = 10/187 (5%)
Frame = -1
Query: 774 KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGI----- 610
K K+A+L+S L +++ + +I V+SN +R +R GI
Sbjct: 803 KVKVAVLISGTGTNLEALINSTKKPTSFAEIVLVVSNKAGVEG---LRKAERAGIPTRVI 859
Query: 609 -SYHYLPTTDQNKIEEEIFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSF 433
Y T+ + + + E + I LA +M++LSG F+K + ++NIH LLPSF
Sbjct: 860 DHKQYGSRTEFDSAVDRVLEEF-SVELICLAGFMRILSGPFVKKWEGKILNIHPSLLPSF 918
Query: 432 KGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKK 253
KG + K +AGV++ G T HFV EE+D+G II Q V D + + ++ ++ E +
Sbjct: 919 KGANAHKLVLEAGVRVTGCTVHFVAEEVDAGAIIFQEAVPVKIGDTVETLSERVKEAEHR 978
Query: 252 CLMKAIK 232
A++
Sbjct: 979 AFPAALQ 985
>sp|Q59A32|PUR2_BOVIN Trifunctional purine biosynthetic protein adenosine-3
OS=Bos taurus GN=GART PE=2 SV=1
Length = 1010
Score = 82 bits (201), Expect = 5e-015
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 10/187 (5%)
Frame = -1
Query: 774 KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNH------ERAPNTHIMRFLQRHG 613
K ++A+L+S L ++ ++ I VISN ++A I + H
Sbjct: 807 KARVAVLISGTGSNLQALIDSTREPSSLAHIVIVISNKAAVAGLDKAEKAGIPTRVINHK 866
Query: 612 ISYHYLPTTDQNKIEEEIFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSF 433
+ Y D I+E + E TD + LA +M++LSG F++ + ++NIH LLPSF
Sbjct: 867 L-YKNRAAFD-TAIDEVLEEF--STDIVCLAGFMRILSGPFVRKWNGKMLNIHPSLLPSF 922
Query: 432 KGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKK 253
KG + +Q DAGV + G T HFV E++D+G II Q V D + + ++ + E K
Sbjct: 923 KGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVETLSERVKLAEHK 982
Query: 252 CLMKAIK 232
A++
Sbjct: 983 IFPSALQ 989
>sp|P22102|PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3
OS=Homo sapiens GN=GART PE=1 SV=1
Length = 1010
Score = 80 bits (195), Expect = 2e-014
Identities = 55/186 (29%), Positives = 95/186 (51%), Gaps = 8/186 (4%)
Frame = -1
Query: 774 KYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYL 595
K ++A+L+S L ++ ++ I VISN + +R GI +
Sbjct: 807 KARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAG---LDKAERAGIPTRVI 863
Query: 594 -PTTDQNKIE-EEIFELVKD---TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFK 430
+N++E + +LV + D + LA +M++LSG F++ + ++NIH LLPSFK
Sbjct: 864 NHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFK 923
Query: 429 GRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLEKKC 250
G + +QA + GV + G T HFV E++D+G II Q V D + + ++ + E K
Sbjct: 924 GSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKI 983
Query: 249 LMKAIK 232
A++
Sbjct: 984 FPAALQ 989
>sp|P08179|PUR3_ECOLI Phosphoribosylglycinamide formyltransferase OS=Escherichia
coli (strain K12) GN=purN PE=1 SV=1
Length = 212
Score = 71 bits (173), Expect = 8e-012
Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Frame = -1
Query: 765 IALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHIMRFLQRHGISYHYLPTT 586
I +L+S L ++ + K+ + V SN A R + GI+ H L +
Sbjct: 3 IVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERAR---QAGIATHTLIAS 59
Query: 585 DQNKIEEEIFELVKDTDF-----IVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKGRS 421
+ E EL+ + D +VLA +M++LS F+ Y ++NIH LLP + G
Sbjct: 60 AFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLH 119
Query: 420 PAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERV---SHRDNLTSFVQKSE 268
+QA + G + G + HFVT+ELD GP+I Q V D++T+ VQ E
Sbjct: 120 THRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQE 173
>sp|P16340|PUR2_DROPS Trifunctional purine biosynthetic protein adenosine-3
OS=Drosophila pseudoobscura pseudoobscura GN=ade3 PE=3 SV=2
Length = 1364
Score = 70 bits (169), Expect = 2e-011
Identities = 56/189 (29%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -1
Query: 777 PKYKIALLLSKQDHCLVEMLHKWQDGKLPV--DITCVISNH------ERAPNTHIMRFLQ 622
P+ ++A+L+S + L ++ +D V +I VISN ERA I +
Sbjct: 1154 PRKRVAVLISGKGSNLQALIDAIRDSAQGVYAEIVLVISNKAGVLGLERAAKAGIPSMV- 1212
Query: 621 RHGISYHYLPTTDQNKIEEEIFELVKDTDFIVLARYMQVLSGNFLKGYGKDVINIHHGLL 442
IS+ P+ + +E +FI LA +M++LS F++ + +INIH LL
Sbjct: 1213 ---ISHKDFPSREVYDVELTRHLKTARVEFICLAGFMRILSVPFVREWRGRLINIHPSLL 1269
Query: 441 PSFKGRSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDL 262
P F G KQA +AG G T H+V E +D+G II Q + D+ + Q+
Sbjct: 1270 PKFPGLHVQKQALEAGETESGCTVHYVDEGVDTGAIIVQAAVPILPGDDEETLTQRIHYA 1329
Query: 261 EKKCLMKAI 235
E +A+
Sbjct: 1330 EHWAFPRAL 1338
>sp|Q5HH12|PUR3_STAAC Phosphoribosylglycinamide formyltransferase
OS=Staphylococcus aureus (strain COL) GN=purN PE=3 SV=1
Length = 188
Score = 69 bits (167), Expect = 4e-011
Identities = 48/176 (27%), Positives = 89/176 (50%), Gaps = 9/176 (5%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLP-VDITCVISNHERAPNTHIMRFLQRHGIS-YHYL 595
KIA+ S ++ + GKL +++T + ++H+ N + ++H I Y
Sbjct: 3 KIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQ---NAFCIDRAKKHDIPVYINE 59
Query: 594 PTTDQNK--IEEEIFELVKD--TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKG 427
P +K E+ + L+ + ++I+LA YM+++ + L + ++NIH LLP +KG
Sbjct: 60 PKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKG 119
Query: 426 RSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLE 259
QA+ +G + G+T H+V +D+G IIEQ + D+ +K + LE
Sbjct: 120 IDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLE 175
>sp|Q6GI12|PUR3_STAAR Phosphoribosylglycinamide formyltransferase
OS=Staphylococcus aureus (strain MRSA252) GN=purN PE=3 SV=1
Length = 188
Score = 68 bits (165), Expect = 7e-011
Identities = 48/176 (27%), Positives = 89/176 (50%), Gaps = 9/176 (5%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLP-VDITCVISNHERAPNTHIMRFLQRHGIS-YHYL 595
KIA+ S ++ + GKL +++T + ++H+ N + ++H I Y
Sbjct: 3 KIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQ---NAFCIDRAKKHDIPVYINE 59
Query: 594 PTTDQNK--IEEEIFELVKD--TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKG 427
P +K E+ + L+ + ++I+LA YM+++ + L + ++NIH LLP +KG
Sbjct: 60 PKQFGSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKG 119
Query: 426 RSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLE 259
QA+ +G + G+T H+V +D+G IIEQ + D+ +K + LE
Sbjct: 120 IDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLE 175
>sp|Q6GAE1|PUR3_STAAS Phosphoribosylglycinamide formyltransferase
OS=Staphylococcus aureus (strain MSSA476) GN=purN PE=3 SV=1
Length = 188
Score = 68 bits (164), Expect = 9e-011
Identities = 48/176 (27%), Positives = 89/176 (50%), Gaps = 9/176 (5%)
Frame = -1
Query: 768 KIALLLSKQDHCLVEMLHKWQDGKLP-VDITCVISNHERAPNTHIMRFLQRHGIS-YHYL 595
KIA+ S ++ + GKL +++T + ++H+ N + ++H I Y
Sbjct: 3 KIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQ---NAFCIDRAKKHDIPVYINE 59
Query: 594 PTTDQNK--IEEEIFELVKD--TDFIVLARYMQVLSGNFLKGYGKDVINIHHGLLPSFKG 427
P +K E+ + L+ + ++I+LA YM+++ + L + ++NIH LLP +KG
Sbjct: 60 PKQFDSKAAYEQHLVSLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKG 119
Query: 426 RSPAKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLTSFVQKSEDLE 259
QA+ +G + G+T H+V +D+G IIEQ + D+ +K + LE
Sbjct: 120 IDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLE 175
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 191,186,815,274
Number of Sequences: 518415
Number of Extensions: 191186815274
Number of Successful Extensions: 1167985300
Number of sequences better than 0.0: 0
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