BLASTX 7.6.2
Query= UN52776 /QuerySize=793
(792 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P60300|CLCG_ARATH Putative chloride channel-like protein CLC-... 404 6e-112
sp|Q96282|CLCC_ARATH Chloride channel protein CLC-c OS=Arabidops... 300 7e-081
sp|P92941|CLCA_ARATH Chloride channel protein CLC-a OS=Arabidops... 267 6e-071
sp|P92942|CLCB_ARATH Chloride channel protein CLC-b OS=Arabidops... 260 1e-068
sp|P92943|CLCD_ARATH Chloride channel protein CLC-d OS=Arabidops... 206 1e-052
sp|P51798|CLCN7_HUMAN H(+)/Cl(-) exchange transporter 7 OS=Homo ... 157 9e-038
sp|O70496|CLCN7_MOUSE H(+)/Cl(-) exchange transporter 7 OS=Mus m... 157 1e-037
sp|P51799|CLCN7_RAT H(+)/Cl(-) exchange transporter 7 OS=Rattus ... 157 1e-037
sp|Q4PKH3|CLCN7_BOVIN H(+)/Cl(-) exchange transporter 7 OS=Bos t... 154 1e-036
sp|Q54AX6|CLCA_DICDI Chloride channel protein A OS=Dictyostelium... 142 3e-033
sp|Q1ZXJ0|CLCD_DICDI Chloride channel protein D OS=Dictyostelium... 136 2e-031
sp|O35454|CLCN6_MOUSE Chloride transport protein 6 OS=Mus muscul... 134 8e-031
sp|Q75JF3|CLCC_DICDI Chloride channel protein C OS=Dictyostelium... 133 1e-030
sp|P51797|CLCN6_HUMAN Chloride transport protein 6 OS=Homo sapie... 132 3e-030
sp|Q9TT16|CLCN6_RABIT Chloride transport protein 6 OS=Oryctolagu... 130 1e-029
sp|Q86AZ6|CLCB_DICDI Chloride channel protein B OS=Dictyostelium... 125 5e-028
sp|P35522|CICH_TORCA Chloride channel protein OS=Torpedo califor... 86 2e-016
sp|P21564|CICH_TORMA Chloride channel protein OS=Torpedo marmora... 83 2e-015
sp|P35523|CLCN1_HUMAN Chloride channel protein 1 OS=Homo sapiens... 73 2e-012
sp|Q9WU45|CLCN2_CAVPO Chloride channel protein 2 OS=Cavia porcel... 72 5e-012
>sp|P60300|CLCG_ARATH Putative chloride channel-like protein CLC-g
OS=Arabidopsis thaliana GN=At5g33280 PE=2 SV=1
Length = 763
Score = 404 bits (1036), Expect = 6e-112
Identities = 199/226 (88%), Positives = 214/226 (94%)
Frame = +3
Query: 114 PLPRHATNSSSQVAIVGSNLCPVESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCF 293
P R ATNS+SQVAIVG+N+CP+ESLDYEIAENDFFKQDWR RSK +IFQYV MKWLLCF
Sbjct: 16 PSLRRATNSTSQVAIVGANVCPIESLDYEIAENDFFKQDWRGRSKVEIFQYVFMKWLLCF 75
Query: 294 FIGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITS 473
IGIIVSLIGF NNLAVENLAGVKFVVTSNMM+AGR++MGF VF+VTNLILTLFAS+IT+
Sbjct: 76 CIGIIVSLIGFANNLAVENLAGVKFVVTSNMMIAGRFAMGFVVFSVTNLILTLFASVITA 135
Query: 474 FVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGA 653
FVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTL++KIIGNISAVS SLLIGKAGPMVHTGA
Sbjct: 136 FVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLIIKIIGNISAVSASLLIGKAGPMVHTGA 195
Query: 654 CVASILGQGGSKRYGLTWRWLRYFNNDRDRRDLVTCGSAAGIAASF 791
CVASILGQGGSKRY LTWRWLR+F NDRDRRDLVTCG+AAGIAASF
Sbjct: 196 CVASILGQGGSKRYRLTWRWLRFFKNDRDRRDLVTCGAAAGIAASF 241
>sp|Q96282|CLCC_ARATH Chloride channel protein CLC-c OS=Arabidopsis thaliana
GN=CLC-C PE=1 SV=1
Length = 779
Score = 300 bits (768), Expect = 7e-081
Identities = 138/225 (61%), Positives = 174/225 (77%)
Frame = +3
Query: 117 LPRHATNSSSQVAIVGSNLCPVESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFF 296
L R+ N++SQ+AIVG+N CP+ESLDYEI ENDFFKQDWR+R K +I QY +KW L F
Sbjct: 42 LARNRKNTTSQIAIVGANTCPIESLDYEIFENDFFKQDWRSRKKIEILQYTFLKWALAFL 101
Query: 297 IGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSF 476
IG+ L+GF NNL VEN+AG K ++ N+ML +Y FF F NLIL A+ + +F
Sbjct: 102 IGLATGLVGFLNNLGVENIAGFKLLLIGNLMLKEKYFQAFFAFAGCNLILATAAASLCAF 161
Query: 477 VAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGAC 656
+APAAAGSGIPEVKAYLNG+DA I + TL VKI G+I V+ ++GK GPMVHTGAC
Sbjct: 162 IAPAAAGSGIPEVKAYLNGIDAYSILAPSTLFVKIFGSIFGVAAGFVVGKEGPMVHTGAC 221
Query: 657 VASILGQGGSKRYGLTWRWLRYFNNDRDRRDLVTCGSAAGIAASF 791
+A++LGQGGSK+Y LTW+WLR+F NDRDRRDL+TCG+AAG+AA+F
Sbjct: 222 IANLLGQGGSKKYRLTWKWLRFFKNDRDRRDLITCGAAAGVAAAF 266
>sp|P92941|CLCA_ARATH Chloride channel protein CLC-a OS=Arabidopsis thaliana
GN=CLC-A PE=1 SV=2
Length = 775
Score = 267 bits (682), Expect = 6e-071
Identities = 123/225 (54%), Positives = 162/225 (72%)
Frame = +3
Query: 117 LPRHATNSSSQVAIVGSNLCPVESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFF 296
L RH T SS+ +A+VG+ + +ESLDYEI END FK DWR+RSK Q+FQY+ +KW L
Sbjct: 33 LKRHRTLSSTPLALVGAKVSHIESLDYEINENDLFKHDWRSRSKAQVFQYIFLKWTLACL 92
Query: 297 IGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSF 476
+G+ LI NLAVEN+AG K + + R+ G VFT NL LTL A+++ +
Sbjct: 93 VGLFTGLIATLINLAVENIAGYKLLAVGYYIAQDRFWTGLMVFTGANLGLTLVATVLVVY 152
Query: 477 VAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGAC 656
AP AAG GIPE+KAYLNG+D P +F T++VKI+G+I AV+ L +GK GP+VH G+C
Sbjct: 153 FAPTAAGPGIPEIKAYLNGIDTPNMFGFTTMMVKIVGSIGAVAAGLDLGKEGPLVHIGSC 212
Query: 657 VASILGQGGSKRYGLTWRWLRYFNNDRDRRDLVTCGSAAGIAASF 791
+AS+LGQGG + + WRWLRYFNNDRDRRDL+TCGSA+G+ A+F
Sbjct: 213 IASLLGQGGPDNHRIKWRWLRYFNNDRDRRDLITCGSASGVCAAF 257
>sp|P92942|CLCB_ARATH Chloride channel protein CLC-b OS=Arabidopsis thaliana
GN=CLC-B PE=1 SV=1
Length = 780
Score = 260 bits (662), Expect = 1e-068
Identities = 122/220 (55%), Positives = 156/220 (70%)
Frame = +3
Query: 132 TNSSSQVAIVGSNLCPVESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIV 311
T SS+ +A+VG+ + +ESLDYEI END FK DWR RSK Q+ QYV +KW L +G+
Sbjct: 37 TLSSTPLALVGAKVSHIESLDYEINENDLFKHDWRKRSKAQVLQYVFLKWTLACLVGLFT 96
Query: 312 SLIGFTNNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAA 491
LI NLAVEN+AG K + + + RY G V NL LTL AS++ AP A
Sbjct: 97 GLIATLINLAVENIAGYKLLAVGHFLTQERYVTGLMVLVGANLGLTLVASVLCVCFAPTA 156
Query: 492 AGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASIL 671
AG GIPE+KAYLNGVD P +F T++VKI+G+I AV+ L +GK GP+VH G+C+AS+L
Sbjct: 157 AGPGIPEIKAYLNGVDTPNMFGATTMIVKIVGSIGAVAAGLDLGKEGPLVHIGSCIASLL 216
Query: 672 GQGGSKRYGLTWRWLRYFNNDRDRRDLVTCGSAAGIAASF 791
GQGG+ + + WRWLRYFNNDRDRRDL+TCGSAAG+ A+F
Sbjct: 217 GQGGTDNHRIKWRWLRYFNNDRDRRDLITCGSAAGVCAAF 256
>sp|P92943|CLCD_ARATH Chloride channel protein CLC-d OS=Arabidopsis thaliana
GN=CLC-D PE=1 SV=2
Length = 792
Score = 206 bits (524), Expect = 1e-052
Identities = 104/204 (50%), Positives = 135/204 (66%), Gaps = 1/204 (0%)
Frame = +3
Query: 180 VESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAG 359
V SLDYE+ EN ++++ R K + YV +KW IGI L NL+VEN AG
Sbjct: 44 VNSLDYEVIENYAYREEQAHRGKLYVGYYVAVKWFFSLLIGIGTGLAAVFINLSVENFAG 103
Query: 360 VKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVD 539
KF +T ++ Y GF V+ + NL+L ++ I + APAAAGSGIPE+K YLNG+D
Sbjct: 104 WKFALTF-AIIQKSYFAGFIVYLLINLVLVFSSAYIITQFAPAAAGSGIPEIKGYLNGID 162
Query: 540 APEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLR 719
P RTL+ KI G+I +V G L +GK GP+VHTGAC+AS+LGQGGS +Y L RW +
Sbjct: 163 IPGTLLFRTLIGKIFGSIGSVGGGLALGKEGPLVHTGACIASLLGQGGSTKYHLNSRWPQ 222
Query: 720 YFNNDRDRRDLVTCGSAAGIAASF 791
F +DRDRRDLVTCG AAG+AA+F
Sbjct: 223 LFKSDRDRRDLVTCGCAAGVAAAF 246
>sp|P51798|CLCN7_HUMAN H(+)/Cl(-) exchange transporter 7 OS=Homo sapiens
GN=CLCN7 PE=1 SV=2
Length = 805
Score = 157 bits (396), Expect = 9e-038
Identities = 79/207 (38%), Positives = 125/207 (60%), Gaps = 4/207 (1%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ +EN F ++ R + T + +W++C IGI+ L+ ++ VENLAG+
Sbjct: 95 ESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGL 154
Query: 363 KF-VVTSNM---MLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
K+ V+ N+ G S ++ N L S+I +F+ P AAGSGIP++K +LN
Sbjct: 155 KYRVIKGNIDKFTEKGGLSFSLLLWATLNAAFVLVGSVIVAFIEPVAAGSGIPQIKCFLN 214
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P + L+TLV+K+ G I +V G L +GK GPM+H+G+ +A+ + QG S ++
Sbjct: 215 GVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFK 274
Query: 711 WLRYFNNDRDRRDLVTCGSAAGIAASF 791
YF D ++RD V+ G+AAG++A+F
Sbjct: 275 IFEYFRRDTEKRDFVSAGAAAGVSAAF 301
>sp|O70496|CLCN7_MOUSE H(+)/Cl(-) exchange transporter 7 OS=Mus musculus
GN=Clcn7 PE=1 SV=1
Length = 803
Score = 157 bits (395), Expect = 1e-037
Identities = 79/207 (38%), Positives = 125/207 (60%), Gaps = 4/207 (1%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ +EN F ++ R + T + +W++C IGI+ L+ ++ VENLAG+
Sbjct: 93 ESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGL 152
Query: 363 KF-VVTSNM---MLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
K+ V+ N+ G S ++ N L S+I +F+ P AAGSGIP++K +LN
Sbjct: 153 KYRVIKDNIDKFTEKGGLSFSLLLWATLNSAFVLVGSVIVAFIEPVAAGSGIPQIKCFLN 212
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P + L+TLV+K+ G I +V G L +GK GPM+H+G+ +A+ + QG S ++
Sbjct: 213 GVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFK 272
Query: 711 WLRYFNNDRDRRDLVTCGSAAGIAASF 791
YF D ++RD V+ G+AAG++A+F
Sbjct: 273 IFEYFRRDTEKRDFVSAGAAAGVSAAF 299
>sp|P51799|CLCN7_RAT H(+)/Cl(-) exchange transporter 7 OS=Rattus norvegicus
GN=Clcn7 PE=2 SV=1
Length = 803
Score = 157 bits (395), Expect = 1e-037
Identities = 79/207 (38%), Positives = 125/207 (60%), Gaps = 4/207 (1%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ +EN F ++ R + T + +W++C IGI+ L+ ++ VENLAG+
Sbjct: 93 ESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGL 152
Query: 363 KF-VVTSNM---MLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
K+ V+ N+ G S ++ N L S+I +F+ P AAGSGIP++K +LN
Sbjct: 153 KYRVIKDNIDKFTEKGGLSFSLLLWATLNSAFVLVGSVIVAFIEPVAAGSGIPQIKCFLN 212
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P + L+TLV+K+ G I +V G L +GK GPM+H+G+ +A+ + QG S ++
Sbjct: 213 GVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFK 272
Query: 711 WLRYFNNDRDRRDLVTCGSAAGIAASF 791
YF D ++RD V+ G+AAG++A+F
Sbjct: 273 IFEYFRRDTEKRDFVSAGAAAGVSAAF 299
>sp|Q4PKH3|CLCN7_BOVIN H(+)/Cl(-) exchange transporter 7 OS=Bos taurus GN=CLCN7
PE=2 SV=1
Length = 809
Score = 154 bits (387), Expect = 1e-036
Identities = 80/230 (34%), Positives = 131/230 (56%), Gaps = 10/230 (4%)
Frame = +3
Query: 114 PLPRHATNSSSQVAIVGSNLCPVESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCF 293
P PR ++ +++ ESLDY+ +EN F ++ R + T + +W++C
Sbjct: 82 PFPREIPHNEKLLSL------KYESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICA 135
Query: 294 FIGIIVSLIGFTNNLAVENLAGVKF-VVTSNM---MLAGRYSMGFFVFTVTNLILTLFAS 461
+GI+ L+ ++ VE LAG+K+ +V N+ G S ++ N L S
Sbjct: 136 MVGILTGLVACFIDIVVEKLAGLKYRLVKDNIDRFTEHGGLSFSLLLWAALNAAFVLLGS 195
Query: 462 LITSFVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMV 641
I +F+ P AAGSGIP++K +LNGV P + L+TLV+K+ G I +V G L +GK GPM+
Sbjct: 196 TIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMI 255
Query: 642 HTGACVASILGQGGSKRYGLTWRWLRYFNNDRDRRDLVTCGSAAGIAASF 791
H+G+ +A+ + QG S ++ YF D ++RD V+ G+AAG++A+F
Sbjct: 256 HSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAF 305
>sp|Q54AX6|CLCA_DICDI Chloride channel protein A OS=Dictyostelium discoideum
GN=clcA PE=2 SV=1
Length = 863
Score = 142 bits (357), Expect = 3e-033
Identities = 75/203 (36%), Positives = 118/203 (58%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLD+ I +N +++ R SK KW++CF IG++V + + +VE +
Sbjct: 96 ESLDFPIIDNQIYREYIRRTSKLNHMLKTFGKWIICFMIGVLVGITAYLVKQSVEFVNEF 155
Query: 363 KFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVDA 542
KF + + R + F V+ N++ + ASL+ V A+GSGIPEVK YLNG+
Sbjct: 156 KFDQSGKYLEDERKFIAFLVYYSINILFGVSASLVIIPVGQIASGSGIPEVKGYLNGIRI 215
Query: 543 PEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLRY 722
P+ +++TLV K++ I A S L++G GPM+H G+ + +GQ SK + L
Sbjct: 216 PQSMNVKTLVGKLVSLILAYSSGLILGPEGPMIHIGSMLGGAIGQVKSKTLKWYPKVLWK 275
Query: 723 FNNDRDRRDLVTCGSAAGIAASF 791
++NDRDRRD ++ G+AAG+AA+F
Sbjct: 276 YHNDRDRRDFISTGAAAGVAAAF 298
>sp|Q1ZXJ0|CLCD_DICDI Chloride channel protein D OS=Dictyostelium discoideum
GN=clcD PE=3 SV=1
Length = 1000
Score = 136 bits (342), Expect = 2e-031
Identities = 70/203 (34%), Positives = 108/203 (53%), Gaps = 1/203 (0%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
E LDY N + + + +++W++ F+GI + +I + ++ V N+
Sbjct: 224 ECLDYVTIYNKAHRNELYKNFSKLASDHEVLRWIVSLFMGIFIGVIAYFSHACVSNITKY 283
Query: 363 KFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVDA 542
KF ++ + + F + + N +L +SL+ + P AAGSGIPEVK YLNG
Sbjct: 284 KFKFVEAVLELDLF-LAFLTYFLLNTLLATCSSLLAVYYEPTAAGSGIPEVKGYLNGTKI 342
Query: 543 PEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLRY 722
P ++TL K + + AVS L G GPM+H GA V + Q SK +G +LR
Sbjct: 343 PHTLKMKTLWTKFLSMVLAVSSGLQAGSEGPMIHIGAIVGNGFSQAQSKEFGFKIPFLRS 402
Query: 723 FNNDRDRRDLVTCGSAAGIAASF 791
F ND+D+RD VT G+ AG+AA+F
Sbjct: 403 FRNDKDKRDFVTSGAGAGVAAAF 425
>sp|O35454|CLCN6_MOUSE Chloride transport protein 6 OS=Mus musculus GN=Clcn6
PE=1 SV=1
Length = 870
Score = 134 bits (336), Expect = 8e-031
Identities = 79/207 (38%), Positives = 112/207 (54%), Gaps = 5/207 (2%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ ND + + + +Y +KW++ F IG+ L+G + +V +
Sbjct: 49 ESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFSVRLFTQL 108
Query: 363 KFVVTSNMM----LAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
KF V + G ++ NL ASL+ + P AAGSGIPE+K YLN
Sbjct: 109 KFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LIEPVAAGSGIPEIKCYLN 167
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P I LRTL+ K+ G + +VSG L +GK GPM+H+GA V + L Q S
Sbjct: 168 GVKVPGIVRLRTLLCKVFGVLFSVSGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQF 227
Query: 711 WLRYFNNDRDRRDLVTCGSAAGIAASF 791
YF +DRD+RD V+ G+AAG+AA+F
Sbjct: 228 NFPYFRSDRDKRDFVSAGAAAGVAAAF 254
>sp|Q75JF3|CLCC_DICDI Chloride channel protein C OS=Dictyostelium discoideum
GN=clcC PE=3 SV=1
Length = 757
Score = 133 bits (334), Expect = 1e-030
Identities = 66/204 (32%), Positives = 109/204 (53%)
Frame = +3
Query: 180 VESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAG 359
++SL++ + +N ++++ +K + KW++C F+G+IV I + + V+ L G
Sbjct: 63 IQSLNFSVNDNLLQREEYEKTTKGLHLKKTFGKWIICLFLGVIVGCIAYVIKMVVQLLQG 122
Query: 360 VKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVD 539
+KF T++ + G F F NL+ + L+ P A+ SGIPEVK LNGV
Sbjct: 123 LKFHYTNHYVSNGLQGEAFLTFLGINLLFVFLSCLMVIVAGPLASSSGIPEVKGILNGVK 182
Query: 540 APEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLR 719
E R L+ KI+ + + S L +G GPM+H G+ V + + Q S G
Sbjct: 183 VREALGFRALLGKIVSLVLSFSSGLFVGPEGPMIHIGSAVGAAISQFKSSTMGFYPSLFL 242
Query: 720 YFNNDRDRRDLVTCGSAAGIAASF 791
+ NDRD+RD ++ G+A G+AA+F
Sbjct: 243 SYRNDRDKRDFISIGAATGLAAAF 266
>sp|P51797|CLCN6_HUMAN Chloride transport protein 6 OS=Homo sapiens GN=CLCN6
PE=1 SV=1
Length = 869
Score = 132 bits (331), Expect = 3e-030
Identities = 78/211 (36%), Positives = 117/211 (55%), Gaps = 13/211 (6%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ ND + + + +Y +KW++ F IG+ L+G + V +
Sbjct: 49 ESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQL 108
Query: 363 KFVVTSNMM----LAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
KF V + G ++ NL ASL+ + P AAGSGIPEVK YLN
Sbjct: 109 KFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LIEPVAAGSGIPEVKCYLN 167
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P I LRTL+ K++G + +V+G L +GK GPM+H+G S++G G + ++ R
Sbjct: 168 GVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSG----SVVGAGLPQFQSISLR 223
Query: 711 WLR----YFNNDRDRRDLVTCGSAAGIAASF 791
++ YF +DRD+RD V+ G+AAG+AA+F
Sbjct: 224 KIQFNFPYFRSDRDKRDFVSAGAAAGVAAAF 254
>sp|Q9TT16|CLCN6_RABIT Chloride transport protein 6 OS=Oryctolagus cuniculus
GN=CLCN6 PE=2 SV=1
Length = 869
Score = 130 bits (326), Expect = 1e-029
Identities = 79/207 (38%), Positives = 110/207 (53%), Gaps = 5/207 (2%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLDY+ ND + + + Y ++KW + F IG+ L+G + V+ +
Sbjct: 49 ESLDYDRCINDPYLEVLETMDHKKGRWYEVVKWTVVFAIGVCTGLVGLFVDFFVQLFTQL 108
Query: 363 KFVV----TSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLN 530
KF V G ++ NL ASL+ + P AAGSGIPE+K YLN
Sbjct: 109 KFGVVEASVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LIEPVAAGSGIPEIKCYLN 167
Query: 531 GVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWR 710
GV P I LRTL+ K+ G + +V+G L +GK GPM+H+GA V + L Q S
Sbjct: 168 GVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQF 227
Query: 711 WLRYFNNDRDRRDLVTCGSAAGIAASF 791
YF +DRD+RD V+ G+AAGIAA+F
Sbjct: 228 NFPYFRSDRDKRDFVSAGAAAGIAAAF 254
>sp|Q86AZ6|CLCB_DICDI Chloride channel protein B OS=Dictyostelium discoideum
GN=clcB PE=3 SV=1
Length = 815
Score = 125 bits (312), Expect = 5e-028
Identities = 69/204 (33%), Positives = 109/204 (53%), Gaps = 1/204 (0%)
Frame = +3
Query: 183 ESLDYEIAENDFFKQDWRARSKTQIFQYVLMKWLLCFFIGIIVSLIGFTNNLAVENLAGV 362
ESLD+ +N ++ + K Q L KW++C IG++V L+ + +V+ L +
Sbjct: 68 ESLDFNAIDNIIHRKYTFEKKKYQKILKTLGKWVICTLIGVVVGLVCYCLKESVDQLQSL 127
Query: 363 KFV-VTSNMMLAGRYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVD 539
K V + F V+ NL L + L+ P ++ SG+PEVK YLNG+
Sbjct: 128 KLTQVKKFYSTESTIFIPFLVYLGFNLCYGLISGLLVCIFGPMSSSSGLPEVKGYLNGIR 187
Query: 540 APEIFSLRTLVVKIIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLR 719
+ F+L+T++ K++ I + S L++G GPM H GA + S + Q SK +
Sbjct: 188 ISKAFNLKTVLGKLVSLIFSFSSGLVLGPEGPMFHIGAGIGSSMSQFKSKTLKFHLKSFW 247
Query: 720 YFNNDRDRRDLVTCGSAAGIAASF 791
F ND D+RD ++CG+AAGIAA+F
Sbjct: 248 IFQNDSDKRDFISCGAAAGIAAAF 271
>sp|P35522|CICH_TORCA Chloride channel protein OS=Torpedo californica PE=1 SV=3
Length = 810
Score = 86 bits (212), Expect = 2e-016
Identities = 58/196 (29%), Positives = 95/196 (48%), Gaps = 23/196 (11%)
Frame = +3
Query: 231 WRARSKTQIFQYVLM----KWLLCFFIGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAG 398
WRA K ++++++ W+ +G +++L+ + + G++F M+ G
Sbjct: 33 WRA-VKNCLYRHLVKVLGEDWIFLLLLGALMALVSWAMDFI--GSRGLRFYKYLFAMVEG 89
Query: 399 RYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVK 578
+ + V+ LIL LF+SL V+P A GSGIPE+K + G E +LRT V K
Sbjct: 90 NLGLQYLVWVCYPLILILFSSLFCQIVSPQAVGSGIPELKTIIRGAVLHEYLTLRTFVAK 149
Query: 579 IIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLRYFNNDRD-----R 743
+G A+S +GK GP VH + A++L Q L + + R+ R
Sbjct: 150 TVGLTVALSAGFPLGKEGPFVHIASICATLLNQ-----------LLCFISGRREEPYYLR 198
Query: 744 RDLVTCGSAAGIAASF 791
D++T G A GI+ F
Sbjct: 199 ADILTVGCALGISCCF 214
>sp|P21564|CICH_TORMA Chloride channel protein OS=Torpedo marmorata PE=1 SV=1
Length = 805
Score = 83 bits (204), Expect = 2e-015
Identities = 56/196 (28%), Positives = 94/196 (47%), Gaps = 23/196 (11%)
Frame = +3
Query: 231 WRARSKTQIFQYVLM----KWLLCFFIGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAG 398
WRA K ++++++ W+ +G +++L+ + + G++F ++ G
Sbjct: 33 WRA-VKNCLYRHLVKVLGEDWIFLLLLGALMALVSWAMDFI--GSRGLRFYKYLFALVEG 89
Query: 399 RYSMGFFVFTVTNLILTLFASLITSFVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVK 578
+ + V+ L L LF+SL V+P A GSGIPE+K + G E +LRT V K
Sbjct: 90 NIGLQYLVWVCYPLALILFSSLFCQIVSPQAVGSGIPELKTIIRGAVLHEYLTLRTFVAK 149
Query: 579 IIGNISAVSGSLLIGKAGPMVHTGACVASILGQGGSKRYGLTWRWLRYFNNDRD-----R 743
+G A+S +GK GP VH + A++L Q L + + R+ R
Sbjct: 150 TVGLTVALSAGFPLGKEGPFVHIASICATLLNQ-----------LLCFISGRREEPYYLR 198
Query: 744 RDLVTCGSAAGIAASF 791
D++T G A GI+ F
Sbjct: 199 ADILTVGCALGISCCF 214
>sp|P35523|CLCN1_HUMAN Chloride channel protein 1 OS=Homo sapiens GN=CLCN1 PE=1
SV=2
Length = 988
Score = 73 bits (177), Expect = 2e-012
Identities = 36/134 (26%), Positives = 73/134 (54%), Gaps = 4/134 (2%)
Frame = +3
Query: 279 WLLCFFIGIIVSLIGFT-NNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLF 455
W+ +G++++L+ ++ + ++ ++L K+ S + + F V+ L+L LF
Sbjct: 118 WIFLVLLGLLMALVSWSMDYVSAKSLQAYKW---SYAQMQPSLPLQFLVWVTFPLVLILF 174
Query: 456 ASLITSFVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGP 635
++L ++P A GSGIPE+K L GV E +++ V K++ + + + +GK GP
Sbjct: 175 SALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGP 234
Query: 636 MVHTGACVASILGQ 677
VH + A++L +
Sbjct: 235 FVHIASICAAVLSK 248
>sp|Q9WU45|CLCN2_CAVPO Chloride channel protein 2 OS=Cavia porcellus GN=CLCN2
PE=2 SV=1
Length = 902
Score = 72 bits (174), Expect = 5e-012
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 2/133 (1%)
Frame = +3
Query: 279 WLLCFFIGIIVSLIGFTNNLAVENLAGVKFVVTSNMMLAGRYSMGFFVFTVTNLILTLFA 458
W+ +G++++L+ + + A+ + ++ L + + + ++L F+
Sbjct: 93 WIFLVLLGLLMALVSWAMDYAIAVCLQAQQWMSQG--LNTNILLQYLAWVTYPVVLITFS 150
Query: 459 SLITSFVAPAAAGSGIPEVKAYLNGVDAPEIFSLRTLVVKIIGNISAVSGSLLIGKAGPM 638
+ T +AP A GSGIPE+K L GV E +L+T V K+IG A+ + +GK GP
Sbjct: 151 AGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFVAKVIGLTCALGSGMPLGKEGPF 210
Query: 639 VHTGACVASILGQ 677
VH + AS+L +
Sbjct: 211 VHIASMCASLLSK 223
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 197,035,034,504
Number of Sequences: 518415
Number of Extensions: 197035034504
Number of Successful Extensions: 1188428614
Number of sequences better than 0.0: 0
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