BLASTX 7.6.2
Query= UN53864 /QuerySize=878
(877 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54493|GLUP_BACSU Rhomboid protease gluP OS=Bacillus subtilis... 78 6e-014
sp|Q6IUY1|RHBL3_TOXGO Rhomboid-like protease 3 OS=Toxoplasma gon... 78 6e-014
sp|A0JPA1|RHDF2_XENTR Rhomboid family member 2 OS=Xenopus tropic... 69 5e-011
sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens... 68 9e-011
sp|Q19821|ROM1_CAEEL Rhomboid-related protein 1 OS=Caenorhabditi... 67 1e-010
sp|Q695U0|RHBL1_TOXGO Rhomboid-like protease 1 OS=Toxoplasma gon... 67 1e-010
sp|P58873|RHBL3_MOUSE Rhomboid-related protein 3 OS=Mus musculus... 66 3e-010
sp|Q6GV23|RHBL5_TOXGO Rhomboid-like protease 5 OS=Toxoplasma gon... 66 3e-010
sp|Q6GMF8|RHDF1_DANRE Rhomboid family member 1 OS=Danio rerio GN... 65 4e-010
sp|P20350|RHOM_DROME Protein rhomboid OS=Drosophila melanogaster... 64 9e-010
sp|Q00M95|RHDF2_CANFA Rhomboid family member 2 OS=Canis familiar... 63 2e-009
sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens G... 63 2e-009
sp|Q80WQ6|RHDF2_MOUSE Rhomboid family member 2 OS=Mus musculus G... 62 5e-009
sp|P96617|YDCA_BACSU Putative rhomboid protease ydcA OS=Bacillus... 59 3e-008
>sp|P54493|GLUP_BACSU Rhomboid protease gluP OS=Bacillus subtilis GN=gluP PE=1
SV=2
Length = 507
Score = 78 bits (191), Expect = 6e-014
Identities = 46/120 (38%), Positives = 74/120 (61%), Gaps = 2/120 (1%)
Frame = +1
Query: 382 SSRTLEKLGSLEWDKVVEKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVR 561
++ TL G+ E + ++ + E WRLLT I LH G+ HLA N L+L +G +E+ +G R
Sbjct: 202 NTETLVAFGAKE-NSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGR 260
Query: 562 IGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLGSMLSELLTNWTIYSNKVHLSMLI 741
+IYL +G+ GSI S +F S GASGA+FG LG++L L+N ++ + ++++
Sbjct: 261 FLLIYLAAGITGSIASFVFSPYP-SAGASGAIFGCLGALLYVALSNRKMFLRTIGTNIIV 319
>sp|Q6IUY1|RHBL3_TOXGO Rhomboid-like protease 3 OS=Toxoplasma gondii GN=ROM3
PE=2 SV=1
Length = 263
Score = 78 bits (191), Expect = 6e-014
Identities = 40/117 (34%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +1
Query: 373 FGPSSRTLEKLGSLEWDKVVEKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFG 552
+ P+ RTL LG+ + + WR++T ++LHA ++HL N++ ++ I +RLE+++G
Sbjct: 60 YEPNERTLMLLGA-AYAPAFSNFQLWRVVTPLFLHATILHLVLNLVFILHISLRLEERYG 118
Query: 553 FVRIGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLGSMLSELLTNWTIYSNKV 723
+ V Y +S + G++LS L ++SVGAS A FG++G M +E+ W S ++
Sbjct: 119 TKKFLVTYFLSAIVGNLLSMLMQPWALSVGASTAGFGIIGGMAAEVSVVWCKLSEEL 175
>sp|A0JPA1|RHDF2_XENTR Rhomboid family member 2 OS=Xenopus tropicalis GN=rhbdf2
PE=2 SV=1
Length = 826
Score = 69 bits (166), Expect = 5e-011
Identities = 36/99 (36%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
Frame = +1
Query: 448 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 627
+RL ++LHAGVIH +++ + + LE+ G++RI +IY++SG+ G++ S+LF+
Sbjct: 625 YRLWLSLFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPY 684
Query: 628 SISVGASGALFGLLGSMLSELLTNWTIYSN--KVHLSML 738
VG +G+ FGLL + EL +W I + K L +L
Sbjct: 685 RAEVGPAGSQFGLLACLFVELFQSWQILAKPWKAFLKLL 723
>sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens GN=RHBDL2 PE=1
SV=2
Length = 303
Score = 68 bits (164), Expect = 9e-011
Identities = 32/90 (35%), Positives = 54/90 (60%)
Frame = +1
Query: 433 EKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSS 612
++ EAWR ++ + +HAGV H+ N+ + +GI LE +R+G++YL + GS+ SS
Sbjct: 116 KREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASS 175
Query: 613 LFIRNSISVGASGALFGLLGSMLSELLTNW 702
+F VGASG ++ L+G +L N+
Sbjct: 176 IFDPLRYLVGASGGVYALMGGYFMNVLVNF 205
>sp|Q19821|ROM1_CAEEL Rhomboid-related protein 1 OS=Caenorhabditis elegans
GN=rom-1 PE=2 SV=2
Length = 356
Score = 67 bits (163), Expect = 1e-010
Identities = 33/87 (37%), Positives = 53/87 (60%)
Frame = +1
Query: 442 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 621
EAWR + ++LHAG+ HL N++ + +GI LE RIG IYL++ GS+L
Sbjct: 165 EAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAID 224
Query: 622 RNSISVGASGALFGLLGSMLSELLTNW 702
NS+ VGAS ++ L+ + ++ ++ NW
Sbjct: 225 PNSLLVGASAGVYALIFAHVANVILNW 251
>sp|Q695U0|RHBL1_TOXGO Rhomboid-like protease 1 OS=Toxoplasma gondii GN=ROM1
PE=2 SV=1
Length = 293
Score = 67 bits (162), Expect = 1e-010
Identities = 34/109 (31%), Positives = 64/109 (58%), Gaps = 2/109 (1%)
Frame = +1
Query: 379 PSSRTLEKLGSLEWDKVVEKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFV 558
P++ L G+ + ++++ + WRLL ++LHA H+ N+ + +G +E+++G +
Sbjct: 88 PAANILVHFGA-NYPPLIKQGQVWRLLLPVFLHANFFHVFFNVFFQLRMGFTIERRYGLL 146
Query: 559 RIGVIYLMSGMGGSILS-SLFIRNSISVGASGALFGLLGSMLSELLTNW 702
+ +Y S + G++LS + F NS+ VGAS A FGL+G + E+ W
Sbjct: 147 KFTGLYFASAIYGNLLSATAFFCNSLKVGASTAGFGLIGIQICEMALTW 195
>sp|P58873|RHBL3_MOUSE Rhomboid-related protein 3 OS=Mus musculus GN=Rhbdl3 PE=2
SV=1
Length = 404
Score = 66 bits (159), Expect = 3e-010
Identities = 30/88 (34%), Positives = 54/88 (61%)
Frame = +1
Query: 442 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 621
+AWR +T I++HAGV L N+ + +G+ LE G RIG++Y+ + GS+ S+
Sbjct: 210 QAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVAD 269
Query: 622 RNSISVGASGALFGLLGSMLSELLTNWT 705
+ VG+SG ++ L+ + L+ ++ NW+
Sbjct: 270 MTAPVVGSSGGVYALVSAHLANIVMNWS 297
>sp|Q6GV23|RHBL5_TOXGO Rhomboid-like protease 5 OS=Toxoplasma gondii GN=ROM5
PE=1 SV=1
Length = 841
Score = 66 bits (159), Expect = 3e-010
Identities = 35/108 (32%), Positives = 65/108 (60%)
Frame = +1
Query: 379 PSSRTLEKLGSLEWDKVVEKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFV 558
P+ R LG+L+ +KV E +R++ ++LH G +HL N+ LE +GF+
Sbjct: 442 PNPRVFSSLGALDTNKVRNYGEMFRVVWGMFLHGGWMHLLLNVSCQAQTLWILEPAWGFL 501
Query: 559 RIGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLGSMLSELLTNW 702
R ++++ G+ GS+LS++ +++VG+SGA +GLLG+++ + W
Sbjct: 502 RTLSLWIVGGVSGSLLSAVANPCTVTVGSSGAFYGLLGALVPFSIEYW 549
>sp|Q6GMF8|RHDF1_DANRE Rhomboid family member 1 OS=Danio rerio GN=rhbdf1 PE=2
SV=1
Length = 857
Score = 65 bits (158), Expect = 4e-010
Identities = 30/87 (34%), Positives = 56/87 (64%)
Frame = +1
Query: 448 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 627
+RL ++LHAG++H ++ + I LE+ G++RI +IY++SG+ G++ S++F+
Sbjct: 656 YRLWLSLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFLPY 715
Query: 628 SISVGASGALFGLLGSMLSELLTNWTI 708
VG +G+ FG+L + EL+ +W I
Sbjct: 716 RAEVGPAGSQFGILACLFVELIQSWQI 742
>sp|P20350|RHOM_DROME Protein rhomboid OS=Drosophila melanogaster GN=rho PE=1
SV=2
Length = 355
Score = 64 bits (155), Expect = 9e-010
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Frame = +1
Query: 442 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 621
+ WR + ++LHA HL N++ +F GI LE G RIGVIY+ GS+ +S+
Sbjct: 149 QVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVD 208
Query: 622 RNSISVGASGALFGLLGSMLSELLTNWT-IYSNKVHLSMLITY*QC 756
VGASG ++ LL + L+ + N+ + S L ++ + C
Sbjct: 209 SEVFLVGASGGVYALLAAHLANITLNYAHMKSASTQLGSVVIFVSC 254
>sp|Q00M95|RHDF2_CANFA Rhomboid family member 2 OS=Canis familiaris GN=RHBDF2
PE=2 SV=1
Length = 827
Score = 63 bits (152), Expect = 2e-009
Identities = 30/87 (34%), Positives = 55/87 (63%)
Frame = +1
Query: 448 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 627
+RL ++LHAGV+H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 626 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 685
Query: 628 SISVGASGALFGLLGSMLSELLTNWTI 708
VG +G+ FGLL + EL +W +
Sbjct: 686 RAEVGPAGSQFGLLACLFVELFQSWQL 712
>sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1
SV=2
Length = 856
Score = 63 bits (152), Expect = 2e-009
Identities = 30/87 (34%), Positives = 55/87 (63%)
Frame = +1
Query: 448 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 627
+RL ++LHAGV+H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 655 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 714
Query: 628 SISVGASGALFGLLGSMLSELLTNWTI 708
VG +G+ FGLL + EL +W +
Sbjct: 715 RAEVGPAGSQFGLLACLFVELFQSWPL 741
>sp|Q80WQ6|RHDF2_MOUSE Rhomboid family member 2 OS=Mus musculus GN=Rhbdf2 PE=1
SV=1
Length = 827
Score = 62 bits (149), Expect = 5e-009
Identities = 28/87 (32%), Positives = 55/87 (63%)
Frame = +1
Query: 448 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 627
+R+ ++LHAG++H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 626 YRIWLSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFILSGITGNLASAIFLPY 685
Query: 628 SISVGASGALFGLLGSMLSELLTNWTI 708
VG +G+ FGLL + EL +W +
Sbjct: 686 RAEVGPAGSQFGLLACLFVELFQSWQL 712
>sp|P96617|YDCA_BACSU Putative rhomboid protease ydcA OS=Bacillus subtilis
GN=ydcA PE=3 SV=1
Length = 199
Score = 59 bits (142), Expect = 3e-008
Identities = 40/106 (37%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Frame = +1
Query: 430 VEKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILS 609
V E WRL+T I LHAG HL N +S+ LE+ G R ++Y SG+ G+I +
Sbjct: 53 VANGEWWRLITPILLHAGFTHLLFNSMSIFLFAPALERMLGKARFLLVYAGSGIIGNIGT 112
Query: 610 SLF-IRNSISVGASGALFGLLGSMLSELLTNWTIYSNKVHLSMLIT 744
+ + + VGASGA+FGL G L +L + + H M+IT
Sbjct: 113 YVTEPLDYVHVGASGAIFGLFGVYLFMVLFRNELIGQE-HSKMIIT 157
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 197,035,034,504
Number of Sequences: 518415
Number of Extensions: 197035034504
Number of Successful Extensions: 1188428614
Number of sequences better than 0.0: 0
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