BLASTX 7.6.2
Query= UN54140 /QuerySize=813
(812 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13709|FSH_DROME Homeotic protein female sterile OS=Drosophil... 89 4e-017
sp|Q91Y44|BRDT_MOUSE Bromodomain testis-specific protein OS=Mus ... 88 5e-017
sp|Q32S26|BRD2_BOVIN Bromodomain-containing protein 2 OS=Bos tau... 87 2e-016
sp|Q5TJG6|BRD2_CANFA Bromodomain-containing protein 2 OS=Canis f... 87 2e-016
sp|P25440|BRD2_HUMAN Bromodomain-containing protein 2 OS=Homo sa... 87 2e-016
sp|Q7JJ13|BRD2_MOUSE Bromodomain-containing protein 2 OS=Mus mus... 87 2e-016
sp|Q6MGA9|BRD2_RAT Bromodomain-containing protein 2 OS=Rattus no... 87 2e-016
sp|Q58F21|BRDT_HUMAN Bromodomain testis-specific protein OS=Homo... 84 1e-015
sp|Q15059|BRD3_HUMAN Bromodomain-containing protein 3 OS=Homo sa... 83 2e-015
sp|Q8K2F0|BRD3_MOUSE Bromodomain-containing protein 3 OS=Mus mus... 83 2e-015
sp|Q54BA2|Y3800_DICDI Ankyrin repeat, bromo and BTB domain-conta... 83 2e-015
sp|Q4R8Y1|BRDT_MACFA Bromodomain testis-specific protein OS=Maca... 83 2e-015
sp|Q9ESU6|BRD4_MOUSE Bromodomain-containing protein 4 OS=Mus mus... 81 9e-015
sp|O60885|BRD4_HUMAN Bromodomain-containing protein 4 OS=Homo sa... 80 1e-014
sp|Q55C84|Y0170_DICDI Bromodomain-containing protein DDB_G027017... 72 3e-012
sp|P45481|CBP_MOUSE CREB-binding protein OS=Mus musculus GN=Creb... 72 4e-012
sp|Q92793|CBP_HUMAN CREB-binding protein OS=Homo sapiens GN=CREB... 69 3e-011
sp|Q09472|EP300_HUMAN Histone acetyltransferase p300 OS=Homo sap... 68 8e-011
sp|Q07442|BDF2_YEAST Bromodomain-containing factor 2 OS=Saccharo... 67 2e-010
>sp|P13709|FSH_DROME Homeotic protein female sterile OS=Drosophila melanogaster
GN=fs(1)h PE=1 SV=2
Length = 2038
Score = 89 bits (218), Expect = 4e-017
Identities = 42/77 (54%), Positives = 54/77 (70%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA+ LGLHDYH I+K+PMDLGTVK K+ + Y+S +FA DVRL F N YN
Sbjct: 501 WPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYN 560
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +M + L ++F
Sbjct: 561 PPDHDVVAMGRKLQDVF 577
Score = 73 bits (177), Expect = 2e-012
Identities = 35/77 (45%), Positives = 47/77 (61%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDAK L L DYH I+K+PMD+GT+K +L + Y S + +D FNN +YN
Sbjct: 57 WPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYN 116
Query: 762 PVGHEVHSMAKFLLNMF 812
G +V MA+ L +F
Sbjct: 117 KPGEDVVVMAQTLEKVF 133
>sp|Q91Y44|BRDT_MOUSE Bromodomain testis-specific protein OS=Mus musculus
GN=Brdt PE=1 SV=2
Length = 956
Score = 88 bits (217), Expect = 5e-017
Identities = 41/77 (53%), Positives = 53/77 (68%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLH+Y+ +VK PMDLGT+KGK+ + Y+ +FA DVRL F N YN
Sbjct: 292 WPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYN 351
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 352 PPDHEVVAMARTLQDVF 368
>sp|Q32S26|BRD2_BOVIN Bromodomain-containing protein 2 OS=Bos taurus GN=BRD2
PE=3 SV=1
Length = 803
Score = 87 bits (213), Expect = 2e-016
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLHDYH I+K PMDL TVK K+ + Y +FA DVRL F+N YN
Sbjct: 370 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 429
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +MA+ L ++F
Sbjct: 430 PPDHDVVAMARKLQDVF 446
>sp|Q5TJG6|BRD2_CANFA Bromodomain-containing protein 2 OS=Canis familiaris
GN=BRD2 PE=3 SV=1
Length = 803
Score = 87 bits (213), Expect = 2e-016
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLHDYH I+K PMDL TVK K+ + Y +FA DVRL F+N YN
Sbjct: 370 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 429
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +MA+ L ++F
Sbjct: 430 PPDHDVVAMARKLQDVF 446
>sp|P25440|BRD2_HUMAN Bromodomain-containing protein 2 OS=Homo sapiens GN=BRD2
PE=1 SV=2
Length = 801
Score = 87 bits (213), Expect = 2e-016
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLHDYH I+K PMDL TVK K+ + Y +FA DVRL F+N YN
Sbjct: 370 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 429
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +MA+ L ++F
Sbjct: 430 PPDHDVVAMARKLQDVF 446
>sp|Q7JJ13|BRD2_MOUSE Bromodomain-containing protein 2 OS=Mus musculus GN=Brd2
PE=1 SV=1
Length = 798
Score = 87 bits (213), Expect = 2e-016
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLHDYH I+K PMDL TVK K+ + Y +FA DVRL F+N YN
Sbjct: 369 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 428
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +MA+ L ++F
Sbjct: 429 PPDHDVVAMARKLQDVF 445
>sp|Q6MGA9|BRD2_RAT Bromodomain-containing protein 2 OS=Rattus norvegicus
GN=Brd2 PE=2 SV=1
Length = 798
Score = 87 bits (213), Expect = 2e-016
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA LGLHDYH I+K PMDL TVK K+ + Y +FA DVRL F+N YN
Sbjct: 369 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 428
Query: 762 PVGHEVHSMAKFLLNMF 812
P H+V +MA+ L ++F
Sbjct: 429 PPDHDVVAMARKLQDVF 445
>sp|Q58F21|BRDT_HUMAN Bromodomain testis-specific protein OS=Homo sapiens
GN=BRDT PE=1 SV=4
Length = 947
Score = 84 bits (205), Expect = 1e-015
Identities = 39/77 (50%), Positives = 50/77 (64%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVD LGLH+Y+ +VK PMDLGT+K K+ + Y+ FA DVRL F N YN
Sbjct: 293 WPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYN 352
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 353 PPDHEVVTMARMLQDVF 369
>sp|Q15059|BRD3_HUMAN Bromodomain-containing protein 3 OS=Homo sapiens GN=BRD3
PE=1 SV=1
Length = 726
Score = 83 bits (204), Expect = 2e-015
Identities = 41/77 (53%), Positives = 49/77 (63%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA+ L LHDYH I+K PMDL TVK K+ Y FA DVRL F+N YN
Sbjct: 332 WPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYN 391
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 392 PPDHEVVAMARKLQDVF 408
>sp|Q8K2F0|BRD3_MOUSE Bromodomain-containing protein 3 OS=Mus musculus GN=Brd3
PE=1 SV=2
Length = 726
Score = 83 bits (204), Expect = 2e-015
Identities = 40/77 (51%), Positives = 49/77 (63%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVDA+ L LHDYH I+K PMDL TVK K+ Y FA D+RL F+N YN
Sbjct: 331 WPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYN 390
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 391 PPDHEVVAMARKLQDVF 407
>sp|Q54BA2|Y3800_DICDI Ankyrin repeat, bromo and BTB domain-containing protein
DDB_G0293800 OS=Dictyostelium discoideum GN=DDB_G0293800 PE=4 SV=1
Length = 806
Score = 83 bits (204), Expect = 2e-015
Identities = 59/205 (28%), Positives = 91/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 198 EEELRRRRRRRITTTTTTTS*ARTDPNQRRSLDQTDRFLSHSHLPRTPSPRRKRTTPCSR 377
E + ++ R + S P +R S T+ + ++ + + ++ T+ S
Sbjct: 414 ETPISEIKQTRTANANASNSNQSKTPAKRTSTTNTNNNIPQQNITSSNNTPQQNTSSSSS 473
Query: 378 SA*AQSPSSKFATLNGN*PPSWTTSGA*SHGSSIPTRRRKQVITRKARLRFSRAATLCFP 557
S+ S SK ++ + S ++S + S SS + + L F +
Sbjct: 474 SSTTSSTPSKSSSSTPSKSTSTSSSSSSSSSSSSSSSSNYSDSMNEKNLTFCKG---LIN 530
Query: 558 S**SIRTGWVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLT 737
+T F PVD G+ DY ++K PMDLGT+KGKL + Y + DFA DVRL
Sbjct: 531 GMFKKKTSLAFQRPVDPLAEGIPDYFDVIKHPMDLGTIKGKLDNNGYSTIKDFAADVRLM 590
Query: 738 FNNAILYNPVGHEVHSMAKFLLNMF 812
F NA+ YN V AK LLN F
Sbjct: 591 FENALTYNADSSPVWKHAKTLLNAF 615
>sp|Q4R8Y1|BRDT_MACFA Bromodomain testis-specific protein OS=Macaca fascicularis
GN=BRDT PE=2 SV=2
Length = 947
Score = 83 bits (203), Expect = 2e-015
Identities = 40/77 (51%), Positives = 50/77 (64%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVD LGLH+Y+ IVK PMDLGT+K K+ + Y+ FA DVRL F N YN
Sbjct: 293 WPFYNPVDVNALGLHNYYDIVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYN 352
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 353 PPDHEVVTMARRLQDVF 369
>sp|Q9ESU6|BRD4_MOUSE Bromodomain-containing protein 4 OS=Mus musculus GN=Brd4
PE=1 SV=1
Length = 1400
Score = 81 bits (198), Expect = 9e-015
Identities = 38/77 (49%), Positives = 48/77 (62%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVD + LGLHDY I+K PMD+ T+K KL Y +F DVRL F+N YN
Sbjct: 375 WPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYN 434
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 435 PPDHEVVAMARKLQDVF 451
>sp|O60885|BRD4_HUMAN Bromodomain-containing protein 4 OS=Homo sapiens GN=BRD4
PE=1 SV=2
Length = 1362
Score = 80 bits (196), Expect = 1e-014
Identities = 38/77 (49%), Positives = 48/77 (62%)
Frame = +3
Query: 582 WVFNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYN 761
W F PVD + LGLHDY I+K PMD+ T+K KL Y +F DVRL F+N YN
Sbjct: 374 WPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYN 433
Query: 762 PVGHEVHSMAKFLLNMF 812
P HEV +MA+ L ++F
Sbjct: 434 PPDHEVVAMARKLQDVF 450
>sp|Q55C84|Y0170_DICDI Bromodomain-containing protein DDB_G0270170
OS=Dictyostelium discoideum GN=DDB_G0270170 PE=4 SV=1
Length = 1578
Score = 72 bits (176), Expect = 3e-012
Identities = 37/75 (49%), Positives = 48/75 (64%)
Frame = +3
Query: 588 FNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYNPV 767
F V VD LG+ DY ++K PMDLGT+K L G Y++ FAED RL F+NA YNP
Sbjct: 760 FLVAVDPYALGILDYFDVIKHPMDLGTIKASLIGGGYDTIDKFAEDCRLVFSNAKTYNPS 819
Query: 768 GHEVHSMAKFLLNMF 812
+ VH MA+ L ++F
Sbjct: 820 TNPVHIMAQSLEDVF 834
>sp|P45481|CBP_MOUSE CREB-binding protein OS=Mus musculus GN=Crebbp PE=1 SV=2
Length = 2441
Score = 72 bits (175), Expect = 4e-012
Identities = 36/75 (48%), Positives = 44/75 (58%)
Frame = +3
Query: 588 FNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYNPV 767
F PVD + LG+ DY IVK PMDL T+K KL G Y+ P + +DVRL FNNA LYN
Sbjct: 1112 FRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRK 1171
Query: 768 GHEVHSMAKFLLNMF 812
V+ L +F
Sbjct: 1172 TSRVYKFCSKLAEVF 1186
>sp|Q92793|CBP_HUMAN CREB-binding protein OS=Homo sapiens GN=CREBBP PE=1 SV=3
Length = 2442
Score = 69 bits (167), Expect = 3e-011
Identities = 35/75 (46%), Positives = 43/75 (57%)
Frame = +3
Query: 588 FNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYNPV 767
F PVD + LG+ DY IVK PMDL T+K KL G Y+ P + +DV L FNNA LYN
Sbjct: 1111 FRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRK 1170
Query: 768 GHEVHSMAKFLLNMF 812
V+ L +F
Sbjct: 1171 TSRVYKFCSKLAEVF 1185
>sp|Q09472|EP300_HUMAN Histone acetyltransferase p300 OS=Homo sapiens GN=EP300
PE=1 SV=2
Length = 2414
Score = 68 bits (164), Expect = 8e-011
Identities = 34/75 (45%), Positives = 43/75 (57%)
Frame = +3
Query: 588 FNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYNPV 767
F PVD + LG+ DY IVK PMDL T+K KL G Y+ P + +D+ L FNNA LYN
Sbjct: 1075 FRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRK 1134
Query: 768 GHEVHSMAKFLLNMF 812
V+ L +F
Sbjct: 1135 TSRVYKYCSKLSEVF 1149
>sp|Q07442|BDF2_YEAST Bromodomain-containing factor 2 OS=Saccharomyces
cerevisiae GN=BDF2 PE=1 SV=1
Length = 638
Score = 67 bits (161), Expect = 2e-010
Identities = 33/75 (44%), Positives = 44/75 (58%)
Frame = +3
Query: 588 FNVPVDAKGLGLHDYHAIVKEPMDLGTVKGKLGDGSYESPLDFAEDVRLTFNNAILYNPV 767
F PVD L L +Y +VK PMDLGT+ L + Y++ F +D+ L F N +NP
Sbjct: 345 FLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPE 404
Query: 768 GHEVHSMAKFLLNMF 812
G+EVHSM K L +F
Sbjct: 405 GNEVHSMGKKLKELF 419
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 197,563,179,902
Number of Sequences: 518415
Number of Extensions: 197563179902
Number of Successful Extensions: 1194541256
Number of sequences better than 0.0: 0
|
