BLASTX 7.6.2
Query= UN54796 /QuerySize=989
(988 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 OS... 186 2e-046
sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabi... 178 9e-044
sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase A6 OS... 170 1e-041
sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase D... 146 3e-034
sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase D... 139 5e-032
sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kin... 132 6e-030
sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kin... 131 8e-030
sp|P18161|PYK2_DICDI Dual specificity protein kinase pyk2 OS=Dic... 118 7e-026
sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dic... 117 1e-025
sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase ki... 111 8e-024
sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/thre... 111 1e-023
sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/thre... 111 1e-023
sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase ki... 109 4e-023
sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase D... 106 4e-022
sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase ki... 105 6e-022
sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase ki... 105 8e-022
sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kina... 105 8e-022
sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase ki... 103 3e-021
sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase ki... 103 3e-021
sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase ki... 99 4e-020
>sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 OS=Arabidopsis
thaliana GN=At2g47470 PE=1 SV=1
Length = 361
Score = 186 bits (472), Expect = 2e-046
Identities = 88/95 (92%), Positives = 91/95 (95%)
Frame = -2
Query: 342 CGHCKKLAPEYEKLGASFKKAKSVLIAKVDCDEHKSVCTKYGVSGYPTIQWFPKGSLEPQ 163
CGHCKKLAPEYEKLGASFKKAKSVLIAKVDCDE KSVCTKYGVSGYPTIQWFPKGSLEPQ
Sbjct: 52 CGHCKKLAPEYEKLGASFKKAKSVLIAKVDCDEQKSVCTKYGVSGYPTIQWFPKGSLEPQ 111
Query: 162 KYEGARNAEALAEYVNKKGGTNVKLAVAPQSLVVL 58
KYEG RNAEALAEYVNK+GGTNVKLA PQ++VVL
Sbjct: 112 KYEGPRNAEALAEYVNKEGGTNVKLAAVPQNVVVL 146
>sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabidopsis thaliana
GN=HT1 PE=1 SV=1
Length = 390
Score = 178 bits (449), Expect = 9e-044
Identities = 83/148 (56%), Positives = 105/148 (70%)
Frame = -2
Query: 981 ALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRW 802
ALD++RGM Y+H + IHRDLKS+NLL++ + +K+ADFG + +E Q GTYRW
Sbjct: 193 ALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQCREAKGNMGTYRW 252
Query: 801 MAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCL 622
MAPEMI+ +PYT+KVDVYSFGIVL EL T LLPFQ MT VQAAFAV + RP +P C
Sbjct: 253 MAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQ 312
Query: 621 PVLGEIMTRCWDADPEVRPCFAEIVNLL 538
P L ++ RCW +P RP F+ IV +L
Sbjct: 313 PALAHLIKRCWSENPSKRPDFSNIVAVL 340
>sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase A6 OS=Medicago
sativa PE=2 SV=1
Length = 364
Score = 170 bits (430), Expect = 1e-041
Identities = 79/95 (83%), Positives = 87/95 (91%)
Frame = -2
Query: 342 CGHCKKLAPEYEKLGASFKKAKSVLIAKVDCDEHKSVCTKYGVSGYPTIQWFPKGSLEPQ 163
CGHCKKLAPEYEKL SFKKAKSVLIAKVDCDEHKSVC+KYGVSGYPTIQWFPKGSLEP+
Sbjct: 58 CGHCKKLAPEYEKLPNSFKKAKSVLIAKVDCDEHKSVCSKYGVSGYPTIQWFPKGSLEPK 117
Query: 162 KYEGARNAEALAEYVNKKGGTNVKLAVAPQSLVVL 58
K+EG R AE+LAE+VN +GGTNVK+A AP +VVL
Sbjct: 118 KFEGPRTAESLAEFVNTEGGTNVKIATAPSHVVVL 152
>sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DDB_G0272254
OS=Dictyostelium discoideum GN=DDB_G0272254 PE=3 SV=1
Length = 1331
Score = 146 bits (367), Expect = 3e-034
Identities = 72/148 (48%), Positives = 95/148 (64%), Gaps = 1/148 (0%)
Frame = -2
Query: 981 ALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRW 802
A D+ARGM ++H RN IHRDLKS NLL+ +IKIAD G+AR T+ MT GT W
Sbjct: 1181 AFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTMT-TIGTVAW 1239
Query: 801 MAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCL 622
APE+++H Y QK DVYS+ IVL EL+TG P+Q + + A V ++G+RP +P +C
Sbjct: 1240 TAPEILRHESYNQKADVYSYAIVLYELLTGEEPYQGIPPMNAGILVASKGLRPELPDNCD 1299
Query: 621 PVLGEIMTRCWDADPEVRPCFAEIVNLL 538
P +++ CW DP RP F EI N L
Sbjct: 1300 PNWKKLVVWCWSEDPNKRPSFEEITNYL 1327
>sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DDB_G0267514
OS=Dictyostelium discoideum GN=DDB_G0267514 PE=3 SV=1
Length = 916
Score = 139 bits (348), Expect = 5e-032
Identities = 66/150 (44%), Positives = 97/150 (64%)
Frame = -2
Query: 987 KQALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTY 808
K A+ +A+GM Y+H IHRD+KS NLL+ ++KI DFG+++++ ++ MT G+
Sbjct: 763 KLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTEMTKSIGSP 822
Query: 807 RWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGD 628
WM+PE++ YT+KVDVY+FGI+L EL TG LP+ + +VQ A AV + +RP +P
Sbjct: 823 IWMSPELLMGEDYTEKVDVYAFGIILWELGTGELPYSGLDSVQLALAVTTKSLRPPIPNA 882
Query: 627 CLPVLGEIMTRCWDADPEVRPCFAEIVNLL 538
L ++ CW DP RP F EI+NLL
Sbjct: 883 WPYQLSHLIQACWHQDPLKRPSFTEILNLL 912
>sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo
sapiens GN=MLTK PE=1 SV=2
Length = 800
Score = 132 bits (330), Expect = 6e-030
Identities = 69/176 (39%), Positives = 104/176 (59%), Gaps = 11/176 (6%)
Frame = -2
Query: 981 ALDVARGMAYVHER---NFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGT 811
A DVA+GM Y+H IHRDLKS N++I+AD +KI DFG +R T M+ GT
Sbjct: 111 ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMS-LVGT 169
Query: 810 YRWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPG 631
+ WMAPE+IQ P ++ D YS+G+VL E++T +PF+ + +Q A+ VV + R T+P
Sbjct: 170 FPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPS 229
Query: 630 DCLPVLGEIMTRCWDADPEVRPCFAEIVNLLGGAETEVMTTVR-------KARFRC 484
C E++ +CW+AD + RP F +I+++L + + KA +RC
Sbjct: 230 SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRC 285
>sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kinase MLT OS=Mus
musculus GN=Mltk PE=1 SV=1
Length = 802
Score = 131 bits (329), Expect = 8e-030
Identities = 65/151 (43%), Positives = 97/151 (64%), Gaps = 4/151 (2%)
Frame = -2
Query: 981 ALDVARGMAYVHER---NFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGT 811
A DVA+GM Y+H IHRDLKS N++I+AD +KI DFG +R T M+ GT
Sbjct: 111 ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMS-LVGT 169
Query: 810 YRWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPG 631
+ WMAPE+IQ P ++ D YS+G+VL E++T +PF+ + +Q A+ VV + R T+P
Sbjct: 170 FPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPS 229
Query: 630 DCLPVLGEIMTRCWDADPEVRPCFAEIVNLL 538
C E++ +CW+AD + RP F +I+++L
Sbjct: 230 SCPRSFAELLHQCWEADAKKRPSFKQIISIL 260
>sp|P18161|PYK2_DICDI Dual specificity protein kinase pyk2 OS=Dictyostelium
discoideum GN=splB PE=2 SV=2
Length = 1155
Score = 118 bits (295), Expect = 7e-026
Identities = 61/150 (40%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
Frame = -2
Query: 975 DVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETG---TYR 805
D+A G+ ++H +HRDL S N+L+ +IKI+DFG++R + + MT G R
Sbjct: 960 DMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGICNPR 1019
Query: 804 WMAPEMIQH-RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGD 628
W PE+ ++ Y++KVDVY F +V+ E++TG +PF ++ QA+ V G+RP +P
Sbjct: 1020 WRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEY 1079
Query: 627 CLPVLGEIMTRCWDADPEVRPCFAEIVNLL 538
C P L ++T+CW+ADP RP F IVN L
Sbjct: 1080 CDPELKLLLTQCWEADPNDRPPFTYIVNKL 1109
>sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium
discoideum GN=pyk3 PE=1 SV=1
Length = 1338
Score = 117 bits (293), Expect = 1e-025
Identities = 59/153 (38%), Positives = 90/153 (58%), Gaps = 7/153 (4%)
Frame = -2
Query: 987 KQALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARI---EVQTEGMTPET 817
K D++ GM ++H +HRDL S N+L+ ++IKIADFG+A ++ G+T
Sbjct: 1153 KMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDDMTLSGIT--- 1209
Query: 816 GTYRWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTV 637
RW +PE+ + Y +KVDVYSFG+V+ E+ TG +PF+ + +A RP +
Sbjct: 1210 -NPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTGKIPFEGLDGTASAAKAAFENYRPAI 1268
Query: 636 PGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLL 538
P DC L +++T+CW +DP RP F EI+ L
Sbjct: 1269 PPDCPVSLRKLITKCWASDPSQRPSFTEILTEL 1301
>sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase OS=Homo
sapiens GN=MLK4 PE=1 SV=1
Length = 1036
Score = 111 bits (277), Expect = 8e-024
Identities = 59/166 (35%), Positives = 95/166 (57%), Gaps = 12/166 (7%)
Frame = -2
Query: 954 YVHERNFI---HRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTY 808
Y+HE F+ HRDLKS N+L+ ++++KI DFG+AR +T M+ GTY
Sbjct: 250 YLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTKMS-TAGTY 308
Query: 807 RWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGD 628
WMAPE+I+ +++ D++S+G++L EL+TG +P++ + + A+ V + +P
Sbjct: 309 AWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPST 368
Query: 627 CLPVLGEIMTRCWDADPEVRPCFAEIVNLLGGAETEVMTTVRKARF 490
C ++M CW DP +RP FA I+ L E VMT + + F
Sbjct: 369 CPEPFAKLMKECWQQDPHIRPSFALILEQLTAIEGAVMTEMPQESF 414
>sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0287001 OS=Dictyostelium discoideum GN=DDB_G0287001 PE=3
SV=1
Length = 650
Score = 111 bits (275), Expect = 1e-023
Identities = 58/148 (39%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -2
Query: 981 ALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRW 802
A D+A M ++H IHRDLKS N+LI+ D + K+ DFG +R + MT GT +
Sbjct: 490 ASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLNLGTSCY 549
Query: 801 MAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCL 622
M+PE+ + Y + DVY+FGIVL E+I P++N+ + +V +G RPT+P DC
Sbjct: 550 MSPELFKGNGYDETCDVYAFGIVLWEIIARKEPYENINSWSIP-VLVAKGERPTIPADCP 608
Query: 621 PVLGEIMTRCWDADPEVRPCFAEIVNLL 538
+++ CW P+ RP F EI + L
Sbjct: 609 SEYSKLIKACWTDKPKKRPSFKEICDTL 636
>sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0286997 OS=Dictyostelium discoideum GN=DDB_G0286997 PE=3
SV=1
Length = 966
Score = 111 bits (275), Expect = 1e-023
Identities = 58/148 (39%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = -2
Query: 981 ALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRW 802
A D+A M ++H IHRDLKS N+LI+ D + K+ DFG +R + MT GT +
Sbjct: 806 ASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMNLGTSCY 865
Query: 801 MAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCL 622
M+PE+ + Y + DVY+FGIVL E+I P++N+ + +V +G RPT+P DC
Sbjct: 866 MSPELFKGNGYDETCDVYAFGIVLWEIIARKEPYENINSWSIP-VMVAKGDRPTIPADCP 924
Query: 621 PVLGEIMTRCWDADPEVRPCFAEIVNLL 538
+++ CW P+ RP F EI + L
Sbjct: 925 SEYSKLIKACWTDKPKKRPSFKEICDTL 952
>sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase kinase OS=Mus
musculus GN=Mlk4 PE=2 SV=2
Length = 1002
Score = 109 bits (271), Expect = 4e-023
Identities = 57/166 (34%), Positives = 95/166 (57%), Gaps = 12/166 (7%)
Frame = -2
Query: 954 YVHER---NFIHRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTY 808
Y+HE +HRDLKS N+L+ ++++KI DFG+AR +T M+ GTY
Sbjct: 234 YLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTRMS-AAGTY 292
Query: 807 RWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGD 628
WMAPE+I+ +++ D++S+G++L EL+TG +P++ + + A+ V + +P
Sbjct: 293 AWMAPEVIRSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPST 352
Query: 627 CLPVLGEIMTRCWDADPEVRPCFAEIVNLLGGAETEVMTTVRKARF 490
C ++M CW+ DP +RP FA I+ L E V+T + + F
Sbjct: 353 CPEPFAKLMKECWEQDPHIRPSFALILQQLTAIEEAVLTNMPQESF 398
>sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DDB_G0282895
OS=Dictyostelium discoideum GN=DDB_G0282895 PE=3 SV=1
Length = 1634
Score = 106 bits (262), Expect = 4e-022
Identities = 53/151 (35%), Positives = 88/151 (58%), Gaps = 1/151 (0%)
Frame = -2
Query: 987 KQALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTY 808
K AL VA+G+AY+H +FIHRD+K+ N+L+ + + K+ DFG++R+ MT GT
Sbjct: 1479 KYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAVAGTP 1538
Query: 807 RWMAPEMIQHRPYTQKVDVYSFGIVLRELITGLLPF-QNMTAVQAAFAVVNRGVRPTVPG 631
+W +PE + YT DVYS+G++L EL TG PF + + V+ A +V ++ ++P +
Sbjct: 1539 KWESPECLMGEAYTSASDVYSYGMMLFELATGDEPFLEIQSIVELARSVCDKKLKPKISS 1598
Query: 630 DCLPVLGEIMTRCWDADPEVRPCFAEIVNLL 538
+ ++ C P+ RP +I+ L
Sbjct: 1599 SVPNFISSLIKDCLHNSPKKRPTMNQIIQKL 1629
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo
sapiens GN=MAP3K11 PE=1 SV=1
Length = 847
Score = 105 bits (261), Expect = 6e-022
Identities = 58/156 (37%), Positives = 91/156 (58%), Gaps = 9/156 (5%)
Frame = -2
Query: 933 IHRDLKSDNLL----ISAD----RSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDLKS+N+L I +D +++KI DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 238 IHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKA 296
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + + A+ V + +P C ++M
Sbjct: 297 STFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMA 356
Query: 597 RCWDADPEVRPCFAEIVNLLGGAETEVMTTVRKARF 490
CW DP RP FA I+ L E +V+ + + F
Sbjct: 357 DCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSF 392
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 OS=Mus
musculus GN=Map3k11 PE=1 SV=1
Length = 850
Score = 105 bits (260), Expect = 8e-022
Identities = 56/156 (35%), Positives = 89/156 (57%), Gaps = 9/156 (5%)
Frame = -2
Query: 933 IHRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDLKS+N+L+ +++KI DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 239 IHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKA 297
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + + A+ V + +P C ++M
Sbjct: 298 STFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMA 357
Query: 597 RCWDADPEVRPCFAEIVNLLGGAETEVMTTVRKARF 490
CW DP RP FA I+ L E +V+ + + F
Sbjct: 358 DCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSF 393
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 OS=Rattus
norvegicus GN=Map3k11 PE=2 SV=1
Length = 850
Score = 105 bits (260), Expect = 8e-022
Identities = 56/156 (35%), Positives = 89/156 (57%), Gaps = 9/156 (5%)
Frame = -2
Query: 933 IHRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDLKS+N+L+ +++KI DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 239 IHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKA 297
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + + A+ V + +P C ++M
Sbjct: 298 STFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMA 357
Query: 597 RCWDADPEVRPCFAEIVNLLGGAETEVMTTVRKARF 490
CW DP RP FA I+ L E +V+ + + F
Sbjct: 358 DCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSF 393
>sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 OS=Homo
sapiens GN=MAP3K10 PE=1 SV=3
Length = 954
Score = 103 bits (255), Expect = 3e-021
Identities = 56/140 (40%), Positives = 81/140 (57%), Gaps = 9/140 (6%)
Frame = -2
Query: 933 IHRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDLKS N+LI AD +KI DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 219 IHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMS-AAGTYAWMAPEVIRL 277
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + A+ A+ V + +P C ++
Sbjct: 278 SLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLE 337
Query: 597 RCWDADPEVRPCFAEIVNLL 538
CWD DP RP F I+ L
Sbjct: 338 ECWDPDPHGRPDFGSILKRL 357
>sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 OS=Mus
musculus GN=Map3k10 PE=2 SV=2
Length = 940
Score = 103 bits (255), Expect = 3e-021
Identities = 56/140 (40%), Positives = 81/140 (57%), Gaps = 9/140 (6%)
Frame = -2
Query: 933 IHRDLKSDNLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDLKS N+LI AD +KI DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 219 IHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMS-AAGTYAWMAPEVIRL 277
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + A+ A+ V + +P C ++
Sbjct: 278 SLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLE 337
Query: 597 RCWDADPEVRPCFAEIVNLL 538
CWD DP RP F I+ L
Sbjct: 338 ECWDPDPHGRPDFGSILKQL 357
>sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10
OS=Xenopus laevis GN=map3k10 PE=1 SV=1
Length = 1005
Score = 99 bits (245), Expect = 4e-020
Identities = 55/148 (37%), Positives = 83/148 (56%), Gaps = 9/148 (6%)
Frame = -2
Query: 933 IHRDLKSDNLLISA--------DRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQH 778
IHRDL S N+LI ++++ I DFG+AR +T M+ GTY WMAPE+I+
Sbjct: 239 IHRDLGSSNILILEKAENDDLFNKTLNITDFGLAREWQKTTKMS-AAGTYAWMAPEVIRL 297
Query: 777 RPYTQKVDVYSFGIVLRELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMT 598
+++ DV+SFG++L EL+TG +P++ + A+ A+ V + +P C I+
Sbjct: 298 SLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILE 357
Query: 597 RCWDADPEVRPCFAEIVNLLGGAETEVM 514
CWD DP RP F+ I+ L E M
Sbjct: 358 ACWDPDPHSRPTFSCILEQLTTIEQSAM 385
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 199,110,431,552
Number of Sequences: 518415
Number of Extensions: 199110431552
Number of Successful Extensions: 1213355657
Number of sequences better than 0.0: 0
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