BLASTX 7.6.2
Query= UN54942 /QuerySize=799
(798 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8TBB5|KLDC4_HUMAN Kelch domain-containing protein 4 OS=Homo ... 167 1e-040
sp|Q921I2|KLDC4_MOUSE Kelch domain-containing protein 4 OS=Mus m... 164 6e-040
sp|Q5R8W1|KLDC4_PONAB Kelch domain-containing protein 4 OS=Pongo... 163 1e-039
sp|Q08979|KEL3_YEAST Kelch repeat-containing protein 3 OS=Saccha... 126 2e-028
sp|Q3KRE6|KLDC2_RAT Kelch domain-containing protein 2 OS=Rattus ... 52 5e-006
sp|Q9Y2U9|KLDC2_HUMAN Kelch domain-containing protein 2 OS=Homo ... 51 7e-006
>sp|Q8TBB5|KLDC4_HUMAN Kelch domain-containing protein 4 OS=Homo sapiens
GN=KLHDC4 PE=1 SV=1
Length = 520
Score = 167 bits (421), Expect = 1e-040
Identities = 88/223 (39%), Positives = 131/223 (58%), Gaps = 11/223 (4%)
Frame = +2
Query: 2 ERFHHYKDFWMLDVKTNQWEHLNLKGCPSPRSGHRMVLYKHKIIVFGVFYDTLREVRYYN 181
E+F+HYKD W+L + T WE + G PS RSGHRMV +K ++I+FG F+++ R+ YYN
Sbjct: 147 EQFYHYKDLWVLHLATKTWEQVKSTGGPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYN 206
Query: 182 DLYVFDLDKYKWQEIKPKPGAMWPTARSGFQFFVY-QDEIFLYGGYSKEVSSEKSSEKGV 358
D+Y F+LD + W ++ P PT RSG Q V Q I +YGGYSK+ +K +KG
Sbjct: 207 DVYAFNLDTFTWSKL--SPSGTGPTPRSGCQMSVTPQGGIVVYGGYSKQ-RVKKDVDKGT 263
Query: 359 VHADLWSLDPR-----TWEWNKVKKIGMPPSSRAGFSVCV-HKKRALLFGGVVDMEMEGD 520
H+D++ L P W W ++ G+ P+ R+GFSV + + L FGGV D E E +
Sbjct: 264 RHSDMFLLKPEDGREDKWVWTRMNPSGVKPTPRSGFSVAMAPNHQTLFFGGVCD-EEEEE 322
Query: 521 VMMSLFLNELYGFQLDNRRWYPIELRKEKSSKDKAKKNLEAKP 649
+ F N+LY + RW+ +L+ KS K K ++ + +P
Sbjct: 323 SLSGEFFNDLYFYDATRNRWFEGQLKGPKSEKKKRRRGRKEEP 365
>sp|Q921I2|KLDC4_MOUSE Kelch domain-containing protein 4 OS=Mus musculus
GN=Klhdc4 PE=1 SV=2
Length = 584
Score = 164 bits (415), Expect = 6e-040
Identities = 86/230 (37%), Positives = 133/230 (57%), Gaps = 11/230 (4%)
Frame = +2
Query: 2 ERFHHYKDFWMLDVKTNQWEHLNLKGCPSPRSGHRMVLYKHKIIVFGVFYDTLREVRYYN 181
E+F+HYKD W+L + T WE + G PS RSGHRMV +K ++I+FG F+++ R+ YY+
Sbjct: 147 EQFYHYKDLWVLHLATKTWEQIRSTGGPSGRSGHRMVAWKRQLILFGGFHESARDYIYYS 206
Query: 182 DLYVFDLDKYKWQEIKPKPGAMWPTARSGFQFFVY-QDEIFLYGGYSKEVSSEKSSEKGV 358
D+Y F LD ++W ++ P PT RSG V Q I +YGGYSK+ +K +KG
Sbjct: 207 DVYTFSLDTFQWSKLSPSGAG--PTPRSGCLMAVTPQGSIAIYGGYSKQ-RVKKDVDKGT 263
Query: 359 VHADLWSLDPR-----TWEWNKVKKIGMPPSSRAGFSVCV-HKKRALLFGGVVDMEMEGD 520
H+D++ L P W W ++ G+ P++R+GFSV V + L+FGGV D E E +
Sbjct: 264 QHSDMFLLKPAEGGEGKWAWTRINPSGVKPTARSGFSVAVAPNHQILVFGGVCD-EEEEE 322
Query: 521 VMMSLFLNELYGFQLDNRRWYPIELRKEKSSKDKAKKNLEAKPIASNDDD 670
+ F ++LY + RW+ +L+ KS K K ++ P + + +
Sbjct: 323 SLEGSFFSDLYIYDAAKSRWFAAQLKGPKSEKKKRRRGKAEDPEGTTEQE 372
>sp|Q5R8W1|KLDC4_PONAB Kelch domain-containing protein 4 OS=Pongo abelii
GN=KLHDC4 PE=2 SV=1
Length = 522
Score = 163 bits (412), Expect = 1e-039
Identities = 85/217 (39%), Positives = 127/217 (58%), Gaps = 11/217 (5%)
Frame = +2
Query: 2 ERFHHYKDFWMLDVKTNQWEHLNLKGCPSPRSGHRMVLYKHKIIVFGVFYDTLREVRYYN 181
E+F+HYKD W+L + T WE + G PS RSGHRMV +K ++I+FG F+++ R+ YYN
Sbjct: 147 EQFYHYKDLWVLHLATKTWEQVKSTGSPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYN 206
Query: 182 DLYVFDLDKYKWQEIKPKPGAMWPTARSGFQFFVY-QDEIFLYGGYSKEVSSEKSSEKGV 358
D+Y F+LD + W ++ P PT RSG Q V Q I +YGGYSK+ +K ++G
Sbjct: 207 DVYTFNLDTFTWSKL--SPSGTGPTPRSGCQMSVTPQGGIIIYGGYSKQ-RVKKDVDRGT 263
Query: 359 VHADLWSLDPR-----TWEWNKVKKIGMPPSSRAGFSVCVH-KKRALLFGGVVDMEMEGD 520
H+D++ L P W W ++ G+ P+ R+GFS + + L FGGV D E E +
Sbjct: 264 RHSDMFLLKPEDGREDKWVWTRMNPSGVKPTPRSGFSAAMALNHQTLFFGGVCD-EEEEE 322
Query: 521 VMMSLFLNELYGFQLDNRRWYPIELRKEKSSKDKAKK 631
+ F N+LY + RW+ +L+ KS K K ++
Sbjct: 323 SLAGEFFNDLYFYDATRNRWFEGQLKGPKSEKKKRRR 359
>sp|Q08979|KEL3_YEAST Kelch repeat-containing protein 3 OS=Saccharomyces
cerevisiae GN=KEL3 PE=1 SV=1
Length = 651
Score = 126 bits (316), Expect = 2e-028
Identities = 74/231 (32%), Positives = 121/231 (52%), Gaps = 16/231 (6%)
Frame = +2
Query: 23 DFWMLDVKTNQWEHLNLKG---CPSPRSGHRMVLYKHKIIVFGVFYDTLR-EVRYYNDLY 190
D W+ D ++ L G PS RSGHR++ +K+ I+FG F D + Y NDL+
Sbjct: 171 DTWLFDCVERKFTKLEFGGRDSSPSARSGHRIIAWKNYFILFGGFRDLGNGQTSYLNDLW 230
Query: 191 VFDLDKYKWQEIKPKPGAMWPTARSGFQFFVYQDEIFLYGGYSKEVS-SEKSSEKGVVHA 367
FD+ YKW +++ P ARSG F + L GGY K ++ + K+ KG +
Sbjct: 231 CFDISTYKWTKLETNSK---PDARSGHCFIPTDNSAILMGGYCKIIAKNNKNLMKGKILN 287
Query: 368 DLWSL----DPRTWEWNKVKKIGMPPSSRAGFSVCVHKK-RALLFGGVVDMEMEGDVMMS 532
D W L DP+ W+W K+K PS R G+S + K+ +++ FGGV D++ + + S
Sbjct: 288 DAWKLNLTPDPKKWQWEKLKNFKNQPSPRVGYSFNLWKQNKSVAFGGVYDLQETEESLES 347
Query: 533 LFLNELYGFQLDNRRWYPIELRKEKSSKDKAKKNLEAKPIASNDDDDDDEM 685
+F N+LY F L+ +W + ++ ++ + KN A ++ D + E+
Sbjct: 348 VFYNDLYMFHLELNKWSKLRIKPQRQTN---SKNSPATSKRKSNKDQEKEL 395
>sp|Q3KRE6|KLDC2_RAT Kelch domain-containing protein 2 OS=Rattus norvegicus
GN=Klhdc2 PE=2 SV=1
Length = 406
Score = 52 bits (122), Expect = 5e-006
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 13/143 (9%)
Frame = +2
Query: 80 CPSPRSGHRMVLYKHKIIVFGVFYDTLREVRY-----YNDLYVFDLDKYKWQEIKPKPGA 244
CP+ RSGH V + V+G + Y +L++++++ +W++I +
Sbjct: 28 CPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDV 87
Query: 245 MWPTARSGFQFFVYQDEIFLYGGYSKEVSSEKSSEKGVVHADLWSLDPRTWEWNKVKKIG 424
P + SG ++L+GG+ ++ K AD R +W ++ G
Sbjct: 88 --PPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSAD------RVLQWERIDCQG 139
Query: 425 MPPSSRAGFSVCVHKKRALLFGG 493
+PPSS+ V V+K + + FGG
Sbjct: 140 IPPSSKDKLGVWVYKNKLIFFGG 162
>sp|Q9Y2U9|KLDC2_HUMAN Kelch domain-containing protein 2 OS=Homo sapiens
GN=KLHDC2 PE=1 SV=1
Length = 406
Score = 51 bits (121), Expect = 7e-006
Identities = 36/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +2
Query: 80 CPSPRSGHRMVLYKHKIIVFGVFYDTLREVRY-----YNDLYVFDLDKYKWQEIKPKPGA 244
CP+ RSGH V + V+G + Y +L++++++ +W++I +
Sbjct: 28 CPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDV 87
Query: 245 MWPTARSGFQFFVYQDEIFLYGGYSKEVSSEKSSEKGVVHADLWSLDPRTWEWNKVKKIG 424
P + SG ++L+GG+ ++ K D S D R +W ++ G
Sbjct: 88 --PPSMSGSCAVCVDRVLYLFGGHHSRGNTNK-----FYMLDSRSTD-RVLQWERIDCQG 139
Query: 425 MPPSSRAGFSVCVHKKRALLFGG 493
+PPSS+ V V+K + + FGG
Sbjct: 140 IPPSSKDKLGVWVYKNKLIFFGG 162
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 199,110,431,552
Number of Sequences: 518415
Number of Extensions: 199110431552
Number of Successful Extensions: 1213355657
Number of sequences better than 0.0: 0
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