BLASTX 7.6.2
Query= UN55967 /QuerySize=807
(806 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1 OS... 273 9e-073
sp|Q6Z9U7|MCES1_ORYSJ mRNA cap guanine-N7 methyltransferase 1 OS... 189 3e-047
sp|O74880|MCES_SCHPO mRNA cap guanine-N7 methyltransferase OS=Sc... 103 2e-021
sp|Q5KKY2|MCES_CRYNE mRNA cap guanine-N7 methyltransferase OS=Cr... 101 8e-021
sp|Q1MTD3|MCES_DANRE mRNA cap guanine-N7 methyltransferase OS=Da... 93 2e-018
sp|Q8SR66|MCES_ENCCU mRNA cap guanine-N7 methyltransferase OS=En... 92 5e-018
sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase OS=Sa... 81 6e-015
sp|Q754U7|MCES_ASHGO mRNA cap guanine-N7 methyltransferase OS=As... 80 1e-014
sp|Q28FT4|MCES_XENTR mRNA cap guanine-N7 methyltransferase OS=Xe... 79 3e-014
sp|Q6CC11|MCES_YARLI mRNA cap guanine-N7 methyltransferase OS=Ya... 79 3e-014
sp|Q6FML4|MCES_CANGA mRNA cap guanine-N7 methyltransferase OS=Ca... 79 4e-014
sp|Q6CKI0|MCES_KLULA mRNA cap guanine-N7 methyltransferase OS=Kl... 78 7e-014
sp|Q9I8S2|MCES_XENLA mRNA cap guanine-N7 methyltransferase OS=Xe... 75 5e-013
sp|Q6BMH4|MCES_DEBHA mRNA cap guanine-N7 methyltransferase OS=De... 70 1e-011
sp|Q5UQX1|MCE_MIMIV Probable mRNA-capping enzyme OS=Acanthamoeba... 63 2e-009
sp|Q9VJQ4|MCES_DROME mRNA cap guanine-N7 methyltransferase OS=Dr... 62 3e-009
sp|Q4R7K1|MCES_MACFA mRNA cap guanine-N7 methyltransferase OS=Ma... 56 2e-007
sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferase OS=Ho... 56 3e-007
sp|Q9D0L8|MCES_MOUSE mRNA cap guanine-N7 methyltransferase OS=Mu... 54 9e-007
sp|Q5U2U7|MCES_RAT mRNA cap guanine-N7 methyltransferase OS=Ratt... 54 9e-007
>sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1 OS=Arabidopsis
thaliana GN=At3g20650 PE=2 SV=1
Length = 370
Score = 273 bits (698), Expect = 9e-073
Identities = 146/190 (76%), Positives = 158/190 (83%), Gaps = 7/190 (3%)
Frame = +3
Query: 243 MKRGFAQSPSSSTPPPSSRFKSNPQGGGDTEYDEEESTKNFARKVADHYSRRTNQTLEER 422
MKRGF+ SPSSS PPPSSRFKSNP+ GD+++ E+E+TKNFARKVADHYSRRTNQTLEER
Sbjct: 1 MKRGFSDSPSSSAPPPSSRFKSNPE--GDSQFLEDETTKNFARKVADHYSRRTNQTLEER 58
Query: 423 EASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEG 602
EASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEG
Sbjct: 59 EASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEG 118
Query: 603 SIEDCRTRYNGDADHHQRRKKSAFHPAYMWG-LFEVH*TDL--ERCPL-ISAVAVAMH-T 767
SIEDCRTRYNGDADHHQRRKK +F + G FEV + E P I + AMH +
Sbjct: 119 SIEDCRTRYNGDADHHQRRKKFSFPSRLLCGDCFEVELDKILEEDAPFDICSCQFAMHYS 178
Query: 768 HDY*ARARRA 797
ARARRA
Sbjct: 179 WTTEARARRA 188
>sp|Q6Z9U7|MCES1_ORYSJ mRNA cap guanine-N7 methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Os08g0180000 PE=2 SV=1
Length = 369
Score = 189 bits (478), Expect = 3e-047
Identities = 97/137 (70%), Positives = 108/137 (78%), Gaps = 5/137 (3%)
Frame = +3
Query: 267 PSSS-TPPPSSRFKSNPQGGGDTEYDEEESTKNFARKVADHYSRRTNQTLEEREASPIIH 443
PSSS P ++ + G G Y EE S+ AR+VADHYS R+NQTLEERE SPIIH
Sbjct: 9 PSSSFASAPKRQYGAGGGGYGGHGYSEERSS---ARRVADHYSARSNQTLEERENSPIIH 65
Query: 444 LKKLNNWIKSVLIQLYARPDDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRT 623
LKKLNNWIKSVLIQLYA P D VLDLACGKGGDLIKWDKA++GYYVG+DIAEGSI+DC T
Sbjct: 66 LKKLNNWIKSVLIQLYAHPGDCVLDLACGKGGDLIKWDKAKVGYYVGVDIAEGSIKDCMT 125
Query: 624 RYNGDADHHQRRKKSAF 674
RYNGD D QRRKK +F
Sbjct: 126 RYNGDTD-QQRRKKFSF 141
>sp|O74880|MCES_SCHPO mRNA cap guanine-N7 methyltransferase
OS=Schizosaccharomyces pombe GN=pcm1 PE=1 SV=1
Length = 389
Score = 103 bits (255), Expect = 2e-021
Identities = 55/119 (46%), Positives = 69/119 (57%), Gaps = 4/119 (3%)
Frame = +3
Query: 285 PPSSRFKSNPQGGGDTEYDEEESTKNFARKVADHYSRRTNQTLEEREASPIIHLKKLNNW 464
P + N G Y+ E+ N V HY+ R + ++R+ SPII LK+ NNW
Sbjct: 64 PRRRDYFQNNDNSGRRGYNRHENNGNAQDVVRSHYNARPDLGYKKRQFSPIIQLKRFNNW 123
Query: 465 IKSVLIQLYARPDD----AVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
IKSVLIQ +A VLD+ CGKGGDLIKWDKA I Y+GIDIAE S+ + RY
Sbjct: 124 IKSVLIQKFAPHASDYPILVLDMGCGKGGDLIKWDKAGIDGYIGIDIAEVSVNQAKKRY 182
>sp|Q5KKY2|MCES_CRYNE mRNA cap guanine-N7 methyltransferase OS=Cryptococcus
neoformans GN=ABD1 PE=3 SV=1
Length = 700
Score = 101 bits (250), Expect = 8e-021
Identities = 50/86 (58%), Positives = 61/86 (70%), Gaps = 1/86 (1%)
Frame = +3
Query: 375 VADHYSRRTNQTLEEREASPIIHLKKLNNWIKSVLIQLYA-RPDDAVLDLACGKGGDLIK 551
VA+HY+ R +E RE SPII LKK NNWIKSVLI +A RP VLD+ CGKGGDL K
Sbjct: 411 VAEHYNSRPEVGVERREFSPIIGLKKFNNWIKSVLIGKFAYRPRGKVLDVGCGKGGDLNK 470
Query: 552 WDKARIGYYVGIDIAEGSIEDCRTRY 629
W +ARI YVG+D+A+ S++ RY
Sbjct: 471 WKQARIALYVGLDVADQSVQQAADRY 496
>sp|Q1MTD3|MCES_DANRE mRNA cap guanine-N7 methyltransferase OS=Danio rerio
GN=rnmt PE=2 SV=1
Length = 400
Score = 93 bits (230), Expect = 2e-018
Identities = 56/134 (41%), Positives = 71/134 (52%), Gaps = 13/134 (9%)
Frame = +3
Query: 270 SSSTPPPSSRFKSNPQGGGDTEYDEEESTKNF-------ARKVADHYSRRTNQTLEEREA 428
SS T SS + GD E D+ +K ++KVA HY++ L ER
Sbjct: 31 SSQTSTSSSSSSVKRRRDGDEEDDDHSPSKKLVTEDSLHSQKVATHYNKIKECGLAERNK 90
Query: 429 SPIIHLKKLNNWIKSVLIQ------LYARPDDAVLDLACGKGGDLIKWDKARIGYYVGID 590
S I++++ NNW+KSVLI R + VLDL CGKGGDL+KW K RI V D
Sbjct: 91 SRIVYMRNFNNWLKSVLIAEILDKVRQKRREVTVLDLGCGKGGDLLKWKKGRIDKLVCAD 150
Query: 591 IAEGSIEDCRTRYN 632
IA SIE C+ RYN
Sbjct: 151 IAAVSIEQCQQRYN 164
>sp|Q8SR66|MCES_ENCCU mRNA cap guanine-N7 methyltransferase OS=Encephalitozoon
cuniculi GN=ABD1 PE=1 SV=1
Length = 298
Score = 92 bits (226), Expect = 5e-018
Identities = 47/120 (39%), Positives = 75/120 (62%), Gaps = 4/120 (3%)
Frame = +3
Query: 336 YDEEESTKNFARKVADHYSRRTNQTLEEREASPIIHLKKLNNWIKSVLIQLYARPDDAVL 515
+ ++++ + ++ +HY+ + E R+ S I+++ NN+IK+ LI+LY + D+VL
Sbjct: 10 FRKDQAMEGKKEEIREHYNSIRERGRESRQRSKTINIRNANNFIKACLIRLYTKRGDSVL 69
Query: 516 DLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRYNGDADHHQRRKKSAFHPAYMWG 695
DL CGKGGDL+K+++A IG Y G+DIAE SI D R R A + +RR K F +G
Sbjct: 70 DLGCGKGGDLLKYERAGIGEYYGVDIAEVSINDARVR----ARNMKRRFKVFFRAQDSYG 125
>sp|P32783|MCES_YEAST mRNA cap guanine-N7 methyltransferase OS=Saccharomyces
cerevisiae GN=ABD1 PE=1 SV=1
Length = 436
Score = 81 bits (199), Expect = 6e-015
Identities = 42/91 (46%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = +3
Query: 360 NFARKVADHYSRRT-NQTLEEREASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKG 536
N + V +HY+ RT +R SPII L+ NN IK +LI Y +P D VL+L CGKG
Sbjct: 117 NVDQIVREHYNERTIIANRAKRNLSPIIKLRNFNNAIKYMLIDKYTKPGDVVLELGCGKG 176
Query: 537 GDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
GDL K+ A I ++GIDI+ SI++ RY
Sbjct: 177 GDLRKYGAAGISQFIGIDISNASIQEAHKRY 207
>sp|Q754U7|MCES_ASHGO mRNA cap guanine-N7 methyltransferase OS=Ashbya gossypii
GN=ABD1 PE=3 SV=1
Length = 430
Score = 80 bits (196), Expect = 1e-014
Identities = 42/91 (46%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 360 NFARKVADHYSRRT-NQTLEEREASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKG 536
N + V +HY+ RT + R SPII L+ NN IK +LI Y RP D VL+L CGKG
Sbjct: 112 NVDQIVREHYNERTFHAKRYNRNYSPIIKLRNFNNAIKYMLIDKYTRPRDVVLELGCGKG 171
Query: 537 GDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
GDL K+ I ++GIDI+ SI + + RY
Sbjct: 172 GDLRKYGACEISQFIGIDISNESIREAQRRY 202
>sp|Q28FT4|MCES_XENTR mRNA cap guanine-N7 methyltransferase OS=Xenopus
tropicalis GN=rnmt PE=2 SV=1
Length = 405
Score = 79 bits (193), Expect = 3e-014
Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 8/133 (6%)
Frame = +3
Query: 255 FAQSPSSSTPPPSSRFKSNPQGGGDTEYDEEES--TKNFARKVADHYSRRTNQTLEEREA 428
F S + PP ++ + G+ E + + V HY+ LE R
Sbjct: 37 FTASGQNLDSPPKNKKSPLKRKAGEPESPSKRPRLEEGHGSLVVTHYNELPETGLETRSQ 96
Query: 429 SPIIHLKKLNNWIKSVLIQLYARP------DDAVLDLACGKGGDLIKWDKARIGYYVGID 590
S I HL+ NNW+KS LI + + AVLDL CGKGGDL+KW K I V D
Sbjct: 97 SRIFHLRNFNNWMKSALIGEFVEKVRQRTRNIAVLDLGCGKGGDLLKWRKGGISKLVCTD 156
Query: 591 IAEGSIEDCRTRY 629
IA+ S++ C RY
Sbjct: 157 IADVSVKQCEERY 169
>sp|Q6CC11|MCES_YARLI mRNA cap guanine-N7 methyltransferase OS=Yarrowia
lipolytica GN=ABD1 PE=3 SV=1
Length = 609
Score = 79 bits (193), Expect = 3e-014
Identities = 38/87 (43%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = +3
Query: 375 VADHYSRRTNQTLEEREASPIIHLKKLNNWIKSVLIQLYARP-DDAVLDLACGKGGDLIK 551
V +HY++ + + R++SPII L+ NN+IKSVLIQ + V+D+ CGKGGDL K
Sbjct: 303 VRNHYNQAPERGVVARQSSPIIKLRNFNNFIKSVLIQKQSLGFGMRVIDMGCGKGGDLNK 362
Query: 552 WDKARIGYYVGIDIAEGSIEDCRTRYN 632
W + R+ Y+G+DIA+ S++ RY+
Sbjct: 363 WSRQRVRDYIGVDIADVSVQQASERYH 389
>sp|Q6FML4|MCES_CANGA mRNA cap guanine-N7 methyltransferase OS=Candida glabrata
GN=ABD1 PE=3 SV=1
Length = 417
Score = 79 bits (192), Expect = 4e-014
Identities = 43/97 (44%), Positives = 57/97 (58%), Gaps = 5/97 (5%)
Frame = +3
Query: 348 ESTKNFARKVADHYSRRT---NQTLEEREASPIIHLKKLNNWIKSVLIQLYARPDDAVLD 518
E N V +HY+ RT N+T +R SPII L+ NN IK +LI + D VL+
Sbjct: 101 EKITNVNNLVREHYNERTYIANRT--KRNQSPIIKLRNFNNAIKFMLIDKFTHTGDVVLE 158
Query: 519 LACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
L CGKGGDL K+ A I ++GIDI+ SI++ RY
Sbjct: 159 LGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRY 195
>sp|Q6CKI0|MCES_KLULA mRNA cap guanine-N7 methyltransferase OS=Kluyveromyces
lactis GN=ABD1 PE=3 SV=1
Length = 426
Score = 78 bits (190), Expect = 7e-014
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 1/92 (1%)
Frame = +3
Query: 360 NFARKVADHYSRRTNQTLE-EREASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKG 536
N V HY+ RT + + R SPII L+ NN IK +LI + R D VL+LACGKG
Sbjct: 114 NVDHVVRQHYNERTFLSKKHNRNYSPIIKLRNFNNAIKYILIDKFTRAGDVVLELACGKG 173
Query: 537 GDLIKWDKARIGYYVGIDIAEGSIEDCRTRYN 632
GDL K+ A I ++GIDI+ SI + RY+
Sbjct: 174 GDLRKYGAAGISQFIGIDISNASITEALKRYH 205
>sp|Q9I8S2|MCES_XENLA mRNA cap guanine-N7 methyltransferase OS=Xenopus laevis
GN=rnmt PE=2 SV=1
Length = 402
Score = 75 bits (183), Expect = 5e-013
Identities = 40/91 (43%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Frame = +3
Query: 375 VADHYSRRTNQTLEEREASPIIHLKKLNNWIKSVLIQLYARP------DDAVLDLACGKG 536
V HY+ LE R S I HL+ NNW+KS LI + + VLDL CGKG
Sbjct: 76 VVTHYNELPETGLEIRSQSRIFHLRNFNNWMKSALIGEFVEKVQQRTRNITVLDLGCGKG 135
Query: 537 GDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
GDL+KW K I V DIA+ S++ C RY
Sbjct: 136 GDLLKWRKGGISKLVCTDIADVSVKQCEQRY 166
>sp|Q6BMH4|MCES_DEBHA mRNA cap guanine-N7 methyltransferase OS=Debaryomyces
hansenii GN=ABD1 PE=3 SV=2
Length = 524
Score = 70 bits (171), Expect = 1e-011
Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 19/156 (12%)
Frame = +3
Query: 246 KRGFAQSPSSSTPPPSSRFKSNPQGGGDTEYD---EEESTKNFARKVADHYSRRTNQTLE 416
KR ++ P S+ +NP + K+ V HY++RT Q+
Sbjct: 148 KRAHDEAEDDVVAPYSNLAVANPSSNLYQTFQSHINNREGKDINSIVRSHYNQRTQQSKF 207
Query: 417 E--REASPIIHLKKLNNWIKSVLIQLYARPD------DAVLDLACGKGGDLIKWDKARIG 572
+ R SPI L+ NN IK +L+ + +P+ +LDL CGKGGDL K + +
Sbjct: 208 QGSRTKSPIYKLRNFNNAIKYILLGNWVKPNPDSNRPTVILDLCCGKGGDLNKCEFVSVD 267
Query: 573 YYVGIDIAEGSIEDCRTRYNGDADHHQRRKKSAFHP 680
Y+GIDI++ SI++ +RY+ R K+ F P
Sbjct: 268 QYIGIDISDASIKEAFSRYS--------RNKARFIP 295
>sp|Q5UQX1|MCE_MIMIV Probable mRNA-capping enzyme OS=Acanthamoeba polyphaga
mimivirus GN=MIMI_R382 PE=1 SV=1
Length = 1170
Score = 63 bits (152), Expect = 2e-009
Identities = 29/62 (46%), Positives = 39/62 (62%)
Frame = +3
Query: 408 TLEEREASPIIHLKKLNNWIKSVLIQLYARPDDAVLDLACGKGGDLIKWDKARIGYYVGI 587
T ++ S ++ NNWIKS +I Y R VLD+ CG+GGDLIK+ A + +YVGI
Sbjct: 677 TYYQKNTSNAAGMRAFNNWIKSNMITTYCRDGSKVLDIGCGRGGDLIKFINAGVEFYVGI 736
Query: 588 DI 593
DI
Sbjct: 737 DI 738
>sp|Q9VJQ4|MCES_DROME mRNA cap guanine-N7 methyltransferase OS=Drosophila
melanogaster GN=l(2)35Bd PE=1 SV=2
Length = 427
Score = 62 bits (150), Expect = 3e-009
Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 7/103 (6%)
Frame = +3
Query: 372 KVADHYSRRTNQTLEEREASPIIHLKKLNNWIKSVLIQLYARPDDA--VLDLACGKGGDL 545
K A R+ ++ R + I + +N ++ I+ R DA VLD+ CGKGGDL
Sbjct: 93 KEAGRKDRQKSKIFFMRNFNNWIKSQLINEYMSQ--IKQNKRMGDALRVLDMCCGKGGDL 150
Query: 546 IKWDKARIGYYVGIDIAEGSIEDCRTRYNGDADHHQRRKKSAF 674
+KW+KA I + + DIAE S+E C+ RY D QR +KS F
Sbjct: 151 LKWEKAAISHLICTDIAEVSVEQCQRRYQ---DILQRSEKSKF 190
>sp|Q4R7K1|MCES_MACFA mRNA cap guanine-N7 methyltransferase OS=Macaca
fascicularis GN=RNMT PE=2 SV=1
Length = 476
Score = 56 bits (134), Expect = 2e-007
Identities = 26/43 (60%), Positives = 30/43 (69%)
Frame = +3
Query: 501 DDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
D VLDL CGKGGDL+KW K RI V DIA+ SI+ C+ RY
Sbjct: 198 DITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSIKQCQQRY 240
>sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferase OS=Homo sapiens
GN=RNMT PE=1 SV=1
Length = 476
Score = 56 bits (133), Expect = 3e-007
Identities = 25/43 (58%), Positives = 30/43 (69%)
Frame = +3
Query: 501 DDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
D VLDL CGKGGDL+KW K RI V DIA+ S++ C+ RY
Sbjct: 198 DITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRY 240
>sp|Q9D0L8|MCES_MOUSE mRNA cap guanine-N7 methyltransferase OS=Mus musculus
GN=Rnmt PE=1 SV=1
Length = 465
Score = 54 bits (129), Expect = 9e-007
Identities = 25/43 (58%), Positives = 30/43 (69%)
Frame = +3
Query: 501 DDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
D VLDL CGKGGDL+KW K RI V DIA+ S++ C+ RY
Sbjct: 187 DITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRY 229
>sp|Q5U2U7|MCES_RAT mRNA cap guanine-N7 methyltransferase OS=Rattus norvegicus
GN=Rnmt PE=2 SV=1
Length = 461
Score = 54 bits (129), Expect = 9e-007
Identities = 25/43 (58%), Positives = 30/43 (69%)
Frame = +3
Query: 501 DDAVLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRY 629
D VLDL CGKGGDL+KW K RI V DIA+ S++ C+ RY
Sbjct: 183 DITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRY 225
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 203,055,350,260
Number of Sequences: 518415
Number of Extensions: 203055350260
Number of Successful Extensions: 1243317088
Number of sequences better than 0.0: 0
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