BLASTX 7.6.2
Query= UN56709 /QuerySize=723
(722 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member ... 182 3e-045
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 180 1e-044
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 179 2e-044
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 172 2e-042
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 171 4e-042
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 171 4e-042
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 171 7e-042
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 169 2e-041
sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member ... 156 2e-037
sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR famil... 145 4e-034
sp|O07575|YHDF_BACSU Uncharacterized oxidoreductase yhdF OS=Baci... 102 2e-021
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 98 4e-020
sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 94 6e-019
sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 94 6e-019
sp|P08694|BPHB_PSEPS Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogen... 92 2e-018
sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ket... 92 3e-018
sp|P80873|GS39_BACSU General stress protein 39 OS=Bacillus subti... 91 9e-018
sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococc... 89 3e-017
sp|P66775|BUTA_STAAM Acetoin(diacetyl) reductase OS=Staphylococc... 89 3e-017
sp|P99120|BUTA_STAAN Acetoin(diacetyl) reductase OS=Staphylococc... 89 3e-017
>sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo
sapiens GN=DHRS2 PE=1 SV=3
Length = 258
Score = 182 bits (460), Expect = 3e-045
Identities = 93/205 (45%), Positives = 130/205 (63%), Gaps = 2/205 (0%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L +VA+VT ST GIGF I R +GA VV+SSRKQ NV+ A+ KL+ +G+ GIVCH
Sbjct: 12 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV K ++ G +D LVC+A NP L T E + DK+ +NVKS LLL
Sbjct: 72 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 131
Query: 429 QDMAPHLE-KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNAV 602
+ P++E + +VI ++SIA + P ++ +Y V+KTALLGLT+ LA E+ P D RVN V
Sbjct: 132 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCV 191
Query: 603 APGFVPTHFASFITGNSQVRESIEE 677
PG + T F+ GN + ++ +E
Sbjct: 192 VPGIIKTDFSKVFHGNESLWKNFKE 216
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 180 bits (455), Expect = 1e-044
Identities = 99/206 (48%), Positives = 131/206 (63%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV V+ +G IDILV NAA NP I+ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEE 677
+APG + T F+ + + + ES++E
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKE 217
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 179 bits (453), Expect = 2e-044
Identities = 98/206 (47%), Positives = 131/206 (63%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV V+ +G IDILV NAA NP ++ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEE 677
+APG + T F+ + + + ES++E
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKE 217
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 172 bits (435), Expect = 2e-042
Identities = 92/206 (44%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
LE KVA+VTAST GIG I R +GA VVVSSRKQ NV+ V L+ +G+ G VCH
Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV V +G +DILV NAA NP I+ E V DK+ +NVK+++L+
Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ ++S+ + P ++ Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEE 677
+APG + T+F+ + + +E ++E
Sbjct: 192 LAPGLIKTNFSQVLWMDKARKEYMKE 217
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 171 bits (433), Expect = 4e-042
Identities = 93/205 (45%), Positives = 131/205 (63%), Gaps = 3/205 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L+ KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV LK +G+ G VCH
Sbjct: 12 LDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV V+ +G +DIL+ NAA +P ++ E V DK+ ++NVK++ LL
Sbjct: 72 VGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLT 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRVNA 599
+ + P + K G S++ ++SIA + P S+ Y V+KTALLGLTK LA E+ + RVN
Sbjct: 132 KAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIE 674
+APG + T F+ + + +ESI+
Sbjct: 192 LAPGLIRTSFSRVLWEDPARQESIK 216
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 171 bits (433), Expect = 4e-042
Identities = 94/206 (45%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV L+ +G+ GIVCH
Sbjct: 12 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R L+ ++++ IDILV NAA NP ++ E V DK+ INV ++ +++
Sbjct: 72 VGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMI 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ + S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEE 677
+APG + T F+S + + I+E
Sbjct: 192 LAPGLIKTRFSSVLWEEKAREDFIKE 217
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 171 bits (431), Expect = 7e-042
Identities = 94/206 (45%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST GIG I R +GA VV+SSRKQ NV+ AV L+ +G+ G+VCH
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV ++ + IDILV NAA NP ++ E V +K+ INV +S +++
Sbjct: 72 VGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMI 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ ++S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEE 677
+APG + THF+S + E I+E
Sbjct: 192 LAPGLIKTHFSSVLWKEKAREEMIKE 217
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 169 bits (427), Expect = 2e-041
Identities = 94/207 (45%), Positives = 127/207 (61%), Gaps = 3/207 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVAIVTAST GIG I R +GA VV+SSRKQ NV+ AV L+++G+ G VCH
Sbjct: 12 LANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCH 71
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV + +G IDILV NAA NP ++ E V DK+ +INVK+ L+
Sbjct: 72 VGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMT 131
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEM-GPDTRVNA 599
+ + P +EK G SV+ + SIA F P + Y V+KTAL+GLTK LA E+ + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNC 191
Query: 600 VAPGFVPTHFASFITGNSQVRESIEEK 680
+APG + T F+ + + E+I +K
Sbjct: 192 LAPGLIKTSFSKALWEDKAQEENIIQK 218
>sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member 4-like 2
OS=Homo sapiens GN=DHRS4L2 PE=2 SV=1
Length = 230
Score = 156 bits (392), Expect = 2e-037
Identities = 87/181 (48%), Positives = 113/181 (62%), Gaps = 3/181 (1%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST GIGF I R + A VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 249 VSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 428
V A+ R LV V+ +G IDILV NAA NP ++ E V DK +INVK+ L+
Sbjct: 88 VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 147
Query: 429 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 599
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGL LA E+ P + RVN
Sbjct: 148 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNC 207
Query: 600 V 602
+
Sbjct: 208 L 208
>sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like
2 OS=Homo sapiens GN=DHRS4L1 PE=5 SV=1
Length = 281
Score = 145 bits (364), Expect = 4e-034
Identities = 85/209 (40%), Positives = 124/209 (59%), Gaps = 6/209 (2%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
L KVA+VTAST IGF + +R +GA VVVS RKQ NV++AV L+ +G+ G VCH
Sbjct: 30 LTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGEGLSMTGTVCH 89
Query: 249 VSNAQHRRDLVEKTVQKYGKIDIL---VCNAAANPSTDPILSTKEAVLDKLWEINVKSSI 419
V + LV ++ +G IDIL + N+ +L T E D+ +IN K+
Sbjct: 90 VGKMKDWERLVATAMKLHGVIDILSLSITNSKRGLFWFTLLQTAEEAWDRNLDINGKALA 149
Query: 420 LLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTR 590
L+++ + P +EK G SV F+ S+A F+P + Y V+KTALLGL K LA E+ P + R
Sbjct: 150 LMIKAVVPEMEKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIR 209
Query: 591 VNAVAPGFVPTHFASFITGNSQVRESIEE 677
VN +APG + T F+ + + + ES++E
Sbjct: 210 VNCLAPGLIKTSFSRMLWMDKEKEESMKE 238
>sp|O07575|YHDF_BACSU Uncharacterized oxidoreductase yhdF OS=Bacillus subtilis
GN=yhdF PE=3 SV=1
Length = 289
Score = 102 bits (254), Expect = 2e-021
Identities = 60/184 (32%), Positives = 100/184 (54%), Gaps = 2/184 (1%)
Frame = +3
Query: 66 RLEGKVAIVTASTQGIGFGIIERFGLEGASV-VVSSRKQANVEEAVEKLKSKGIDAYGIV 242
+L+GKVAI+T GIG F EGA + ++ + ++ EE ++++ + + I
Sbjct: 42 KLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIP 101
Query: 243 CHVSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSIL 422
V + H V++TV +GK+DILV NAA D IL+ L+K + N+ S
Sbjct: 102 GDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFH 161
Query: 423 LLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRVNA 599
+ + PHL++G ++I TSI ++ ++ Y TK A++ T+++A + RVNA
Sbjct: 162 MTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNA 221
Query: 600 VAPG 611
VAPG
Sbjct: 222 VAPG 225
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 98 bits (243), Expect = 4e-020
Identities = 72/214 (33%), Positives = 112/214 (52%), Gaps = 19/214 (8%)
Frame = +3
Query: 69 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 248
LEG A+VT ++GIG+GI+E GASV SR Q ++E + + +SKG + VC
Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEASVCD 66
Query: 249 VSNAQHRRDLVEKTVQK--YGKIDILVCNAAANPSTDPILSTKEAV------LDKLWEIN 404
+S+ R + + KTV +GK++ILV NA I+ KEA + IN
Sbjct: 67 LSSRSEREEFM-KTVSNHFHGKLNILVNNAG-------IVIYKEAKDYTMEDYSHIMSIN 118
Query: 405 VKSSILLLQDMAPHLE--KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG 578
+++ L P L+ + +V+FI+SI+G A+YG TK A+ LT+ LA E
Sbjct: 119 FEAAYHLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWA 178
Query: 579 PDT-RVNAVAPGFVPTHFASFITGNSQVRESIEE 677
D RVN V PG + T + + +E++++
Sbjct: 179 KDNIRVNGVGPGVIATSMVEMTIQDPEQKENLDK 212
>sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
O157:H7 GN=hdhA PE=3 SV=1
Length = 255
Score = 94 bits (233), Expect = 6e-019
Identities = 71/213 (33%), Positives = 105/213 (49%), Gaps = 16/213 (7%)
Frame = +3
Query: 66 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 245
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 246 HVSNAQHRRDLVEKTVQKYGKIDILVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 416
+++ Q L + + K GK+DILV NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 417 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 587
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 588 RVNAVAPGFVPTHFASFITGNSQVRESIEEKTL 686
RVN +APG + T S + IE+K L
Sbjct: 183 RVNGIAPGAILTDAL-----KSVITPEIEQKML 210
>sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
(strain K12) GN=hdhA PE=1 SV=1
Length = 255
Score = 94 bits (233), Expect = 6e-019
Identities = 71/213 (33%), Positives = 105/213 (49%), Gaps = 16/213 (7%)
Frame = +3
Query: 66 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 245
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 246 HVSNAQHRRDLVEKTVQKYGKIDILVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 416
+++ Q L + + K GK+DILV NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 417 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 587
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 588 RVNAVAPGFVPTHFASFITGNSQVRESIEEKTL 686
RVN +APG + T S + IE+K L
Sbjct: 183 RVNGIAPGAILTDAL-----KSVITPEIEQKML 210
>sp|P08694|BPHB_PSEPS Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
OS=Pseudomonas pseudoalcaligenes GN=bphB PE=3 SV=2
Length = 275
Score = 92 bits (228), Expect = 2e-018
Identities = 56/186 (30%), Positives = 92/186 (49%), Gaps = 8/186 (4%)
Frame = +3
Query: 66 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 245
+L+G+ ++T G+G +++RF E V+ + E E G + GIV
Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEAKVAVLDK----SAERLAELETDLGDNVLGIVG 57
Query: 246 HVSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKE----AVLDKLWEINVKS 413
V + + ++ + V ++GKID L+ NA + ++ E A D+++ INVK
Sbjct: 58 DVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKG 117
Query: 414 SILLLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPDTRV 593
I ++ + + +VIF S AGF P G +Y K A++GL + LA E+ P RV
Sbjct: 118 YIHAVKALPALVASRGNVIFTISNAGFYPNGGGPLYTAAKQAIVGLVRELAFELAPYVRV 177
Query: 594 NAVAPG 611
N V PG
Sbjct: 178 NGVGPG 183
>sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ketoacyl reductase
1 OS=Streptomyces violaceoruber GN=gra-orf5 PE=3 SV=1
Length = 272
Score = 92 bits (227), Expect = 3e-018
Identities = 64/193 (33%), Positives = 93/193 (48%), Gaps = 14/193 (7%)
Frame = +3
Query: 81 VAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSNA 260
VA+VT +T GIG I R GA + +R + + + V++L+ +G D G VC V++
Sbjct: 19 VALVTGATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDVADP 78
Query: 261 QHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLW----EINVKSSILLL 428
R V VQ+YG +DILV NA + + D+LW N+ S L+
Sbjct: 79 AQIRAYVAAAVQRYGTVDILVNNAGRSGG-----GATAEIADELWLDVITTNLTSVFLMT 133
Query: 429 QDM----APHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRV 593
+++ +K +I I S G Q Y +K ++GLTKAL E+ V
Sbjct: 134 KEVLNAGGMLAKKRGRIINIASTGGKQGVVHAVPYSASKHGVVGLTKALGLELARTGITV 193
Query: 594 NAVAPGFVPTHFA 632
NAV PGFV T A
Sbjct: 194 NAVCPGFVETPMA 206
>sp|P80873|GS39_BACSU General stress protein 39 OS=Bacillus subtilis GN=ydaD
PE=1 SV=3
Length = 286
Score = 91 bits (223), Expect = 9e-018
Identities = 60/193 (31%), Positives = 97/193 (50%), Gaps = 2/193 (1%)
Frame = +3
Query: 39 EMEGKKIGRRLEGKVAIVTASTQGIGFGIIERFGLEGASV-VVSSRKQANVEEAVEKLKS 215
E E K +L+GKVA++T GIG + + EGA + +V + + EE ++++
Sbjct: 30 EYEDYKGADKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQ 89
Query: 216 KGIDAYGIVCHVSNAQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLW 395
+G+ I V + + VEKTV++ G +DILV NA + I L + +
Sbjct: 90 EGVKCLLIAGDVGEEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTF 149
Query: 396 EINVKSSILLLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEM 575
+ N S L + +L+ GS++I TSI + ++ Y TK A+ T+ +A +
Sbjct: 150 KTNFYSQFYLTKKAIDYLKPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQAL 209
Query: 576 GPD-TRVNAVAPG 611
D RVNAVAPG
Sbjct: 210 VKDGIRVNAVAPG 222
>sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain COL) GN=butA PE=3 SV=1
Length = 258
Score = 89 bits (219), Expect = 3e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 78 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 257
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 258 AQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 437
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 438 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 605
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 606 PGFVPT 623
PG V T
Sbjct: 184 PGIVQT 189
>sp|P66775|BUTA_STAAM Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain Mu50 / ATCC 700699) GN=butA PE=3 SV=1
Length = 258
Score = 89 bits (219), Expect = 3e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 78 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 257
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 258 AQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 437
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 438 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 605
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 606 PGFVPT 623
PG V T
Sbjct: 184 PGIVQT 189
>sp|P99120|BUTA_STAAN Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain N315) GN=butA PE=1 SV=1
Length = 258
Score = 89 bits (219), Expect = 3e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 78 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 257
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 258 AQHRRDLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 437
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 438 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 605
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 606 PGFVPT 623
PG V T
Sbjct: 184 PGIVQT 189
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 203,055,350,260
Number of Sequences: 518415
Number of Extensions: 203055350260
Number of Successful Extensions: 1243317088
Number of sequences better than 0.0: 0
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