BLASTX 7.6.2
Query= UN57610 /QuerySize=786
(785 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus ... 97 1e-019
sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porce... 88 5e-017
sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapien... 85 4e-016
sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fasc... 84 1e-015
sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculu... 83 2e-015
sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus... 57 1e-007
sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase OS=Sus... 52 4e-006
>sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus GN=MAN2B1 PE=1
SV=3
Length = 999
Score = 97 bits (239), Expect = 1e-019
Identities = 71/219 (32%), Positives = 107/219 (48%), Gaps = 16/219 (7%)
Frame = -1
Query: 785 RATGGGSIKDGELELMLHRRTCMDDSRGVEESLEETVCINGTCTGLTVRGSYYVSINKVG 606
R+ GG S++DG LELM+HRR DD+RGV E L N +GL VRG + V ++K
Sbjct: 786 RSQGGSSLRDGSLELMVHRRLLKDDARGVGEPL------NKEGSGLWVRGRHLVLLDKKE 839
Query: 605 GEGARWRRGTGQEIYSPLLMAFTHKNKEKWKGSNSVKGNAMDPLYAFPPNVALITLQELD 426
AR R E+ +P ++ +++ + + PP+V L+TL
Sbjct: 840 TAAARHRLQAEMEVLAPQVV-LAQGGGARYRLEKAPRTQFSGLRRELPPSVRLLTLARWG 898
Query: 425 LGNVLLRLAHLYEAGEES--EYSKVAKVELKKLFTGKTIKGVKEMSLAATQEKAKMKEKM 252
+LLRL H + GE+S S ++L LF+ TI ++E +LAA Q A ++
Sbjct: 899 PETLLLRLEHQFAVGEDSGRNLSSPVTLDLTNLFSAFTITNLRETTLAANQLLA-YASRL 957
Query: 251 KWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRTFL 135
+W + + T P + + L PMEIRTFL
Sbjct: 958 QWTTD------TGPTPHPSPSRPVSATITLQPMEIRTFL 990
>sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porcellus GN=MAN2B1
PE=1 SV=1
Length = 1007
Score = 88 bits (217), Expect = 5e-017
Identities = 75/227 (33%), Positives = 113/227 (49%), Gaps = 29/227 (12%)
Frame = -1
Query: 785 RATGGGSIKDGELELMLHRRTCMDDSRGVEESLEETVCINGTCTGLTVRGSYYVSINKVG 606
R+ GG S+ DG LELM+HRR DD RGV E+L+E +G VRG + + ++
Sbjct: 791 RSQGGSSMSDGSLELMVHRRLLKDDGRGVGEALQE------PGSGGWVRGRHLLLLDTAR 844
Query: 605 GEGARWRRGTGQEIYSPLLM-------AFTHKNKEKWKGSNSVKGNAMDPL-YAFPPNVA 450
A R +E+ +P L+ ++ H + E +V L PP+V
Sbjct: 845 EAAAEHRLLAEKELLAPQLVLAPGQGPSYHHDHHE------AVPRKQFSGLRRQLPPSVR 898
Query: 449 LITLQELDLGNVLLRLAHLYEAGEES--EYSKVAKVELKKLFTGKTIKGVKEMSLAATQE 276
L+TL +LLRL H + GE+S S ++L+ LF+ TI ++E +LAA Q
Sbjct: 899 LLTLARWGPDTLLLRLEHQFALGEDSSRNLSLPVTLDLQDLFSTFTITRLQETTLAANQL 958
Query: 275 KAKMKEKMKWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRTFL 135
+A ++KW E + + V LD S+ + L PMEIRTF+
Sbjct: 959 RAS-ASRLKWTTEIDPISRPA----VPRLDPSS--ITLQPMEIRTFV 998
>sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapiens GN=MAN2B1
PE=1 SV=3
Length = 1011
Score = 85 bits (209), Expect = 4e-016
Identities = 72/224 (32%), Positives = 102/224 (45%), Gaps = 30/224 (13%)
Frame = -1
Query: 785 RATGGGSIKDGELELMLHRRTCMDDSRGVEESLEETVCINGTCTGLTVRGSYYVSINKVG 606
R+ GG S++DG LELM+HRR DD RGV E L E NG +G VRG + V ++
Sbjct: 797 RSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLME----NG--SGAWVRGRHLVLLDTAQ 850
Query: 605 GEGARWRRGTGQEIYSPLLMAFTHKNKEKWKGSNSVKGNAMDPLYAF-------PPNVAL 447
A R QE+ +P ++ G + P F PP+V L
Sbjct: 851 AAAAGHRLLAEQEVLAPQVVLA--------PGGGAAYNLGAPPRTQFSGLRRDLPPSVHL 902
Query: 446 ITLQELDLGNVLLRLAHLYEAGEES--EYSKVAKVELKKLFTGKTIKGVKEMSLAATQEK 273
+TL VLLRL H + GE+S S + L+ LF+ TI ++E +L A Q +
Sbjct: 903 LTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLR 962
Query: 272 AKMKEKMKWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRT 141
+ ++KW ++ T P + L PMEIRT
Sbjct: 963 -EAASRLKW------TTNTGPTPHQTPYQLDPANITLEPMEIRT 999
>sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fascicularis
GN=MAN2B1 PE=2 SV=1
Length = 1012
Score = 84 bits (206), Expect = 1e-015
Identities = 71/224 (31%), Positives = 102/224 (45%), Gaps = 30/224 (13%)
Frame = -1
Query: 785 RATGGGSIKDGELELMLHRRTCMDDSRGVEESLEETVCINGTCTGLTVRGSYYVSINKVG 606
R+ GG S++DG LELM+HRR DD RGV E L E NG +G VRG + V ++
Sbjct: 798 RSQGGSSLRDGSLELMVHRRLLKDDERGVSEPLME----NG--SGAWVRGRHLVLLDTAQ 851
Query: 605 GEGARWRRGTGQEIYSPLLMAFTHKNKEKWKGSNSVKGNAMDPLYAF-------PPNVAL 447
A R QE+ +P ++ G + P F PP+V L
Sbjct: 852 AAAAGHRLLAEQEVLAPQVVLA--------PGGGAAYNLGAPPRTQFSGLRRELPPSVHL 903
Query: 446 ITLQELDLGNVLLRLAHLYEAGEES--EYSKVAKVELKKLFTGKTIKGVKEMSLAATQEK 273
+TL +LLRL H + GE+S S + L+ LF+ TI ++E +L A Q +
Sbjct: 904 LTLASWGPEMLLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLR 963
Query: 272 AKMKEKMKWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRT 141
+ ++KW ++ T P + L PMEIRT
Sbjct: 964 -EAASRLKW------TTNTGPTPHQTPYQLDPANITLEPMEIRT 1000
>sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculus GN=Man2b1
PE=2 SV=3
Length = 1013
Score = 83 bits (204), Expect = 2e-015
Identities = 61/182 (33%), Positives = 91/182 (50%), Gaps = 10/182 (5%)
Frame = -1
Query: 785 RATGGGSIKDGELELMLHRRTCMDDSRGVEESLEETVCINGTCTGLTVRGSYYVSINKVG 606
R+ GG S++DG LELM+HRR +DD RGV E L E T TG VRG + V ++ V
Sbjct: 798 RSQGGSSLQDGSLELMVHRRLLVDDDRGVSEPLLE------TDTGDKVRGRHLVLLSSVS 851
Query: 605 GEGARWRRGTGQEIYSPLLMAFTHKNKEKWKGSNSVKGNAMDPLYAFPPNVALITLQELD 426
AR R QE+ +P ++ + + + K PP V L+TL
Sbjct: 852 DAAARHRLLAEQEVLAPQVV-LSLGGSSPYHSRATPKTQFSGLRQELPPQVHLLTLARWG 910
Query: 425 LGNVLLRLAHLYEAGEESE--YSKVAKVELKKLFTGKTIKGVKEMSLAATQEKAKMKEKM 252
+LLRL H + E+S+ S + ++ LF TI ++E +LAA Q ++ ++
Sbjct: 911 PKMLLLRLEHQFALKEDSDRNLSSPVTLNVQNLFQTFTINYLQETTLAANQPLSR-ASRL 969
Query: 251 KW 246
KW
Sbjct: 970 KW 971
>sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus GN=MAN2B1 PE=2
SV=1
Length = 1007
Score = 57 bits (136), Expect = 1e-007
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 8/111 (7%)
Frame = -1
Query: 464 PPNVALITLQELDLGNVLLRLAHLYEAGEES-EYSKVAKVELKKLFTGKTIKGVKEMSLA 288
PP+V L+TL D +LLRL H + GE+S S ++L LF+ TI ++E +L
Sbjct: 895 PPSVHLLTLARWDQKTLLLRLEHQFAVGEDSGNLSSPVTLDLTDLFSAFTITYLQETTLV 954
Query: 287 ATQEKAKMKEKMKWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRTFL 135
A Q +A ++KW ++ T P + L PMEIRTFL
Sbjct: 955 ANQLRAS-ASRLKW------TPNTGPTPLPSPSRLDPATITLQPMEIRTFL 998
>sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase OS=Sus scrofa
GN=MAN2B2 PE=1 SV=2
Length = 995
Score = 52 bits (123), Expect = 4e-006
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = -1
Query: 428 DLGNVLLRLAHLYEAGEESEYSKVAKVELKKLFTG-KTIKGVKEMSLAATQEKAKMKEKM 252
D VLLRL HLYEAGE S+ + L+ + G ++ V+E SL T + + +
Sbjct: 894 DFRRVLLRLHHLYEAGEHQALSRPVTLNLQSVLRGLGSVVAVEERSLTGTWDVNSL-HRW 952
Query: 251 KWKVEGEEAKSSSHTQKVGPLDSSALVVELAPMEIRTFLLQF 126
WK E S + + PL + + P EIRTF + F
Sbjct: 953 SWKTEDGHHHRGSSRRPLPPLRGPNVTIH--PKEIRTFFIHF 992
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 205,079,028,280
Number of Sequences: 518415
Number of Extensions: 205079028280
Number of Successful Extensions: 1272460166
Number of sequences better than 0.0: 0
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