BLASTX 7.6.2
Query= UN58424 /QuerySize=749
(748 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 77 8e-014
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 75 4e-013
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 72 5e-012
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 71 8e-012
sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xeno... 71 8e-012
sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xeno... 70 1e-011
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 70 2e-011
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 69 2e-011
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 69 3e-011
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 69 3e-011
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 68 5e-011
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 68 5e-011
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 68 7e-011
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 67 1e-010
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 67 1e-010
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 65 3e-010
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 64 7e-010
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 58 5e-008
sp|Q63364|PJA2_RAT E3 ubiquitin-protein ligase Praja-2 OS=Rattus... 55 3e-007
sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 55 4e-007
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 77 bits (189), Expect = 8e-014
Identities = 26/72 (36%), Positives = 45/72 (62%)
Frame = -2
Query: 711 SQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEEDVATTT 532
+++ C +CKE ++ + +E+PC H +HP C+ PWL NSCP+CRHELP +++
Sbjct: 226 AEAECCICKENLVIGDKMQELPCKHTFHPPCLKPWLDEHNSCPICRHELPTDDQKYENWK 285
Query: 531 VAEEDSGDSSAG 496
E+++ + G
Sbjct: 286 EREKEAEEERKG 297
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 75 bits (183), Expect = 4e-013
Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 6/73 (8%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPA------EEEDVAT 538
CAVCK+ ++ +++PC H YH DCI+PWL RNSCPVCR +L EE T
Sbjct: 257 CAVCKDGMVMGETGKKLPCGHCYHGDCIVPWLGTRNSCPVCRFQLETDDAEYEEERKKRT 316
Query: 537 TTVAEEDSGDSSA 499
+TV++ + SS+
Sbjct: 317 STVSDSAAASSSS 329
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 72 bits (174), Expect = 5e-012
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = -2
Query: 717 SDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEE 550
S ++ C VC F A EMPC+H++H +CILPWL+ NSCP+CRHELP +++
Sbjct: 70 SQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDD 125
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 71 bits (172), Expect = 8e-012
Identities = 26/62 (41%), Positives = 38/62 (61%)
Frame = -2
Query: 738 IAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPA 559
+ T + D C VCKE + + E R++PCNH +H CI+PWL + ++CPVCR L
Sbjct: 215 VTVTQEQVDMGLECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNG 274
Query: 558 EE 553
E+
Sbjct: 275 ED 276
>sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xenopus laevis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 71 bits (172), Expect = 8e-012
Identities = 28/65 (43%), Positives = 39/65 (60%)
Frame = -2
Query: 741 EIAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELP 562
++ T ++D+ C VC F R++PC H++H CILPWL NSCP+CRHELP
Sbjct: 65 KVTVTPEQADAALKCPVCLLEFEEGETVRQLPCEHLFHSACILPWLGKTNSCPLCRHELP 124
Query: 561 AEEED 547
+ D
Sbjct: 125 TDSPD 129
>sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xenopus tropicalis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 70 bits (170), Expect = 1e-011
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = -2
Query: 741 EIAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELP 562
++ T ++D+ C VC F R++PC H++H CILPWL NSCP+CRHELP
Sbjct: 65 KVTVTPEQADAALKCPVCLLEFEEGETVRQLPCEHLFHSSCILPWLGKTNSCPLCRHELP 124
Query: 561 AEEED 547
+ +
Sbjct: 125 TDSPE 129
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 70 bits (169), Expect = 2e-011
Identities = 27/56 (48%), Positives = 38/56 (67%)
Frame = -2
Query: 717 SDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEE 550
S ++ C VC F EMPC+H++H +CILPWL+ NSCP+CRHELP +++
Sbjct: 82 SKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDD 137
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 69 bits (168), Expect = 2e-011
Identities = 26/50 (52%), Positives = 35/50 (70%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEE 550
C VC F EMPC+H++H +CILPWL+ NSCP+CRHELP +++
Sbjct: 88 CPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDD 137
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 69 bits (167), Expect = 3e-011
Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
Frame = -2
Query: 744 IEIAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHEL 565
I+I H+ S + C VCKE + + R++PCNH++H DCI+PWL ++CPVCR L
Sbjct: 214 IQITEEHVGSGLE--CPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSL 271
Query: 564 PAE 556
+
Sbjct: 272 SGQ 274
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 69 bits (167), Expect = 3e-011
Identities = 27/56 (48%), Positives = 38/56 (67%)
Frame = -2
Query: 717 SDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEE 550
S ++ C VC F A EMPC+H++H CILPWL+ NSCP+CR+ELP +++
Sbjct: 70 SQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYELPTDDD 125
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 68 bits (165), Expect = 5e-011
Identities = 24/62 (38%), Positives = 39/62 (62%)
Frame = -2
Query: 738 IAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPA 559
+ T + ++ C VCKE + + + R++PCNH +H CI+PWL + ++CPVCR L
Sbjct: 216 VTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNG 275
Query: 558 EE 553
E+
Sbjct: 276 ED 277
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 68 bits (165), Expect = 5e-011
Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = -2
Query: 747 VIEIAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHE 568
V+ I+P ++D C VC F REMPC H++H CILPWL NSCP+CR E
Sbjct: 65 VVIISPE--QADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWLNKTNSCPLCRLE 122
Query: 567 LPAEEED 547
LP + D
Sbjct: 123 LPTDNAD 129
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 68 bits (164), Expect = 7e-011
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Frame = -2
Query: 744 IEIAPTHLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHEL 565
I+I H+ S + C VCKE + + R++PCNH++H DCI+PWL ++CPVCR L
Sbjct: 215 IQITEEHVGSGLE--CPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSL 272
Query: 564 PAEEEDVATTTVAEEDSGDSS 502
+ ++E SS
Sbjct: 273 SGQNTATNPPGLSEMTFSSSS 293
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 67 bits (162), Expect = 1e-010
Identities = 23/48 (47%), Positives = 33/48 (68%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAE 556
C VCKE + + R++PCNH++H DCI+PWL ++CPVCR L +
Sbjct: 228 CPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQ 275
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 67 bits (162), Expect = 1e-010
Identities = 24/48 (50%), Positives = 32/48 (66%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAE 556
C VCKE + L R++PCNH++H CI+PWL +SCPVCR L +
Sbjct: 231 CPVCKEDYALGESVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSLTGQ 278
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 65 bits (158), Expect = 3e-010
Identities = 23/48 (47%), Positives = 32/48 (66%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAE 556
C VCK+ + L R++PCNH++H CI+PWL +SCPVCR L +
Sbjct: 229 CPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQ 276
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 64 bits (155), Expect = 7e-010
Identities = 23/48 (47%), Positives = 32/48 (66%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAE 556
C VCK+ + L R++PCNH++H CI+PWL +SCPVCR L +
Sbjct: 232 CPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQ 279
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 58 bits (139), Expect = 5e-008
Identities = 23/49 (46%), Positives = 32/49 (65%)
Frame = -2
Query: 699 CAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEE 553
C+VCKE + R +PC H +H +CIL WL NSCP+CR+EL ++
Sbjct: 70 CSVCKEPAEEGQKYRILPCKHEFHEECILLWLKKTNSCPLCRYELETDD 118
>sp|Q63364|PJA2_RAT E3 ubiquitin-protein ligase Praja-2 OS=Rattus norvegicus
GN=Pja2 PE=2 SV=1
Length = 707
Score = 55 bits (132), Expect = 3e-007
Identities = 23/76 (30%), Positives = 34/76 (44%)
Frame = -2
Query: 726 HLESDSQSHCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCRHELPAEEED 547
H + C +C ++ A E+PC+H +H C+ WL +CPVCR P D
Sbjct: 624 HTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWLQKSGTCPVCRRHFPPAVID 683
Query: 546 VATTTVAEEDSGDSSA 499
+ +E D S A
Sbjct: 684 ASAAASSEPDLDASPA 699
>sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1
Length = 419
Score = 55 bits (131), Expect = 4e-007
Identities = 18/43 (41%), Positives = 29/43 (67%)
Frame = -2
Query: 702 HCAVCKETFLLSSEAREMPCNHIYHPDCILPWLAIRNSCPVCR 574
HCAVC E++ + R +PC H++H C+ PWL+ +CP+C+
Sbjct: 263 HCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCK 305
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 208,048,610,154
Number of Sequences: 518415
Number of Extensions: 208048610154
Number of Successful Extensions: 1281187403
Number of sequences better than 0.0: 0
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