BLASTX 7.6.2
Query= UN59555 /QuerySize=742
(741 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54493|GLUP_BACSU Rhomboid protease gluP OS=Bacillus subtilis... 72 3e-012
sp|Q6IUY1|RHBL3_TOXGO Rhomboid-like protease 3 OS=Toxoplasma gon... 71 6e-012
sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens... 66 2e-010
sp|Q6GV23|RHBL5_TOXGO Rhomboid-like protease 5 OS=Toxoplasma gon... 63 2e-009
sp|A0JPA1|RHDF2_XENTR Rhomboid family member 2 OS=Xenopus tropic... 62 4e-009
sp|Q19821|ROM1_CAEEL Rhomboid-related protein 1 OS=Caenorhabditi... 61 8e-009
sp|Q695U0|RHBL1_TOXGO Rhomboid-like protease 1 OS=Toxoplasma gon... 60 1e-008
sp|P20350|RHOM_DROME Protein rhomboid OS=Drosophila melanogaster... 59 3e-008
sp|Q6GMF8|RHDF1_DANRE Rhomboid family member 1 OS=Danio rerio GN... 58 5e-008
sp|Q00M95|RHDF2_CANFA Rhomboid family member 2 OS=Canis familiar... 58 5e-008
sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens G... 58 7e-008
sp|P58873|RHBL3_MOUSE Rhomboid-related protein 3 OS=Mus musculus... 57 1e-007
sp|Q80WQ6|RHDF2_MOUSE Rhomboid family member 2 OS=Mus musculus G... 57 1e-007
sp|P96617|YDCA_BACSU Putative rhomboid protease ydcA OS=Bacillus... 57 1e-007
>sp|P54493|GLUP_BACSU Rhomboid protease gluP OS=Bacillus subtilis GN=gluP PE=1
SV=2
Length = 507
Score = 72 bits (176), Expect = 3e-012
Identities = 43/98 (43%), Positives = 62/98 (63%), Gaps = 2/98 (2%)
Frame = +3
Query: 405 SSRTLEKLGSLEWDKVVGKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVR 584
++ TL G+ E + ++ + E WRLLT I LH G+ HLA N L+L +G +E+ +G R
Sbjct: 202 NTETLVAFGAKE-NSLIAQGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGR 260
Query: 585 IGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLGS 698
+IYL +G+ GSI S +F S GASGA+FG LG+
Sbjct: 261 FLLIYLAAGITGSIASFVFSPYP-SAGASGAIFGCLGA 297
>sp|Q6IUY1|RHBL3_TOXGO Rhomboid-like protease 3 OS=Toxoplasma gondii GN=ROM3
PE=2 SV=1
Length = 263
Score = 71 bits (173), Expect = 6e-012
Identities = 36/100 (36%), Positives = 64/100 (64%), Gaps = 1/100 (1%)
Frame = +3
Query: 396 FGPSSRTLEKLGSLEWDKVVGKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFG 575
+ P+ RTL LG+ + + WR++T ++LHA ++HL N++ ++ I +RLE+++G
Sbjct: 60 YEPNERTLMLLGA-AYAPAFSNFQLWRVVTPLFLHATILHLVLNLVFILHISLRLEERYG 118
Query: 576 FVRIGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLG 695
+ V Y +S + G++LS L ++SVGAS A FG++G
Sbjct: 119 TKKFLVTYFLSAIVGNLLSMLMQPWALSVGASTAGFGIIG 158
>sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens GN=RHBDL2 PE=1
SV=2
Length = 303
Score = 66 bits (159), Expect = 2e-010
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +3
Query: 459 KHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSL 638
+ EAWR ++ + +HAGV H+ N+ + +GI LE +R+G++YL + GS+ SS+
Sbjct: 117 REEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSI 176
Query: 639 FIRNSISVGASGALFGLLGSCFL 707
F VGASG ++ L+G F+
Sbjct: 177 FDPLRYLVGASGGVYALMGGYFM 199
>sp|Q6GV23|RHBL5_TOXGO Rhomboid-like protease 5 OS=Toxoplasma gondii GN=ROM5
PE=1 SV=1
Length = 841
Score = 63 bits (152), Expect = 2e-009
Identities = 34/99 (34%), Positives = 61/99 (61%)
Frame = +3
Query: 402 PSSRTLEKLGSLEWDKVVGKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFV 581
P+ R LG+L+ +KV E +R++ ++LH G +HL N+ LE +GF+
Sbjct: 442 PNPRVFSSLGALDTNKVRNYGEMFRVVWGMFLHGGWMHLLLNVSCQAQTLWILEPAWGFL 501
Query: 582 RIGVIYLMSGMGGSILSSLFIRNSISVGASGALFGLLGS 698
R ++++ G+ GS+LS++ +++VG+SGA +GLLG+
Sbjct: 502 RTLSLWIVGGVSGSLLSAVANPCTVTVGSSGAFYGLLGA 540
>sp|A0JPA1|RHDF2_XENTR Rhomboid family member 2 OS=Xenopus tropicalis GN=rhbdf2
PE=2 SV=1
Length = 826
Score = 62 bits (149), Expect = 4e-009
Identities = 31/83 (37%), Positives = 53/83 (63%)
Frame = +3
Query: 471 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 650
+RL ++LHAGVIH +++ + + LE+ G++RI +IY++SG+ G++ S+LF+
Sbjct: 625 YRLWLSLFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPY 684
Query: 651 SISVGASGALFGLLGSCFLTSHQ 719
VG +G+ FGLL F+ Q
Sbjct: 685 RAEVGPAGSQFGLLACLFVELFQ 707
>sp|Q19821|ROM1_CAEEL Rhomboid-related protein 1 OS=Caenorhabditis elegans
GN=rom-1 PE=2 SV=2
Length = 356
Score = 61 bits (146), Expect = 8e-009
Identities = 31/76 (40%), Positives = 46/76 (60%)
Frame = +3
Query: 465 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 644
EAWR + ++LHAG+ HL N++ + +GI LE RIG IYL++ GS+L
Sbjct: 165 EAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAID 224
Query: 645 RNSISVGASGALFGLL 692
NS+ VGAS ++ L+
Sbjct: 225 PNSLLVGASAGVYALI 240
>sp|Q695U0|RHBL1_TOXGO Rhomboid-like protease 1 OS=Toxoplasma gondii GN=ROM1
PE=2 SV=1
Length = 293
Score = 60 bits (144), Expect = 1e-008
Identities = 32/99 (32%), Positives = 59/99 (59%), Gaps = 2/99 (2%)
Frame = +3
Query: 402 PSSRTLEKLGSLEWDKVVGKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFV 581
P++ L G+ + ++ + + WRLL ++LHA H+ N+ + +G +E+++G +
Sbjct: 88 PAANILVHFGA-NYPPLIKQGQVWRLLLPVFLHANFFHVFFNVFFQLRMGFTIERRYGLL 146
Query: 582 RIGVIYLMSGMGGSILS-SLFIRNSISVGASGALFGLLG 695
+ +Y S + G++LS + F NS+ VGAS A FGL+G
Sbjct: 147 KFTGLYFASAIYGNLLSATAFFCNSLKVGASTAGFGLIG 185
>sp|P20350|RHOM_DROME Protein rhomboid OS=Drosophila melanogaster GN=rho PE=1
SV=2
Length = 355
Score = 59 bits (141), Expect = 3e-008
Identities = 30/78 (38%), Positives = 44/78 (56%)
Frame = +3
Query: 465 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 644
+ WR + ++LHA HL N++ +F GI LE G RIGVIY+ GS+ +S+
Sbjct: 149 QVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVD 208
Query: 645 RNSISVGASGALFGLLGS 698
VGASG ++ LL +
Sbjct: 209 SEVFLVGASGGVYALLAA 226
>sp|Q6GMF8|RHDF1_DANRE Rhomboid family member 1 OS=Danio rerio GN=rhbdf1 PE=2
SV=1
Length = 857
Score = 58 bits (139), Expect = 5e-008
Identities = 27/79 (34%), Positives = 51/79 (64%)
Frame = +3
Query: 471 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 650
+RL ++LHAG++H ++ + I LE+ G++RI +IY++SG+ G++ S++F+
Sbjct: 656 YRLWLSLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFLPY 715
Query: 651 SISVGASGALFGLLGSCFL 707
VG +G+ FG+L F+
Sbjct: 716 RAEVGPAGSQFGILACLFV 734
>sp|Q00M95|RHDF2_CANFA Rhomboid family member 2 OS=Canis familiaris GN=RHBDF2
PE=2 SV=1
Length = 827
Score = 58 bits (139), Expect = 5e-008
Identities = 31/88 (35%), Positives = 54/88 (61%)
Frame = +3
Query: 471 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 650
+RL ++LHAGV+H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 626 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 685
Query: 651 SISVGASGALFGLLGSCFLTSHQLDYLL 734
VG +G+ FGLL F+ Q LL
Sbjct: 686 RAEVGPAGSQFGLLACLFVELFQSWQLL 713
>sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1
SV=2
Length = 856
Score = 58 bits (138), Expect = 7e-008
Identities = 29/83 (34%), Positives = 52/83 (62%)
Frame = +3
Query: 471 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 650
+RL ++LHAGV+H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 655 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 714
Query: 651 SISVGASGALFGLLGSCFLTSHQ 719
VG +G+ FGLL F+ Q
Sbjct: 715 RAEVGPAGSQFGLLACLFVELFQ 737
>sp|P58873|RHBL3_MOUSE Rhomboid-related protein 3 OS=Mus musculus GN=Rhbdl3 PE=2
SV=1
Length = 404
Score = 57 bits (136), Expect = 1e-007
Identities = 27/78 (34%), Positives = 47/78 (60%)
Frame = +3
Query: 465 EAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFI 644
+AWR +T I++HAGV L N+ + +G+ LE G RIG++Y+ + GS+ S+
Sbjct: 210 QAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVAD 269
Query: 645 RNSISVGASGALFGLLGS 698
+ VG+SG ++ L+ +
Sbjct: 270 MTAPVVGSSGGVYALVSA 287
>sp|Q80WQ6|RHDF2_MOUSE Rhomboid family member 2 OS=Mus musculus GN=Rhbdf2 PE=1
SV=1
Length = 827
Score = 57 bits (136), Expect = 1e-007
Identities = 29/88 (32%), Positives = 54/88 (61%)
Frame = +3
Query: 471 WRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILSSLFIRN 650
+R+ ++LHAG++H +++ + I LE+ G+ RI +I+++SG+ G++ S++F+
Sbjct: 626 YRIWLSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFILSGITGNLASAIFLPY 685
Query: 651 SISVGASGALFGLLGSCFLTSHQLDYLL 734
VG +G+ FGLL F+ Q LL
Sbjct: 686 RAEVGPAGSQFGLLACLFVELFQSWQLL 713
>sp|P96617|YDCA_BACSU Putative rhomboid protease ydcA OS=Bacillus subtilis
GN=ydcA PE=3 SV=1
Length = 199
Score = 57 bits (136), Expect = 1e-007
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +3
Query: 453 VGKHEAWRLLTCIWLHAGVIHLAANMLSLVFIGIRLEQQFGFVRIGVIYLMSGMGGSILS 632
V E WRL+T I LHAG HL N +S+ LE+ G R ++Y SG+ G+I +
Sbjct: 53 VANGEWWRLITPILLHAGFTHLLFNSMSIFLFAPALERMLGKARFLLVYAGSGIIGNIGT 112
Query: 633 SLF-IRNSISVGASGALFGLLG 695
+ + + VGASGA+FGL G
Sbjct: 113 YVTEPLDYVHVGASGAIFGLFG 134
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 210,982,208,808
Number of Sequences: 518415
Number of Extensions: 210982208808
Number of Successful Extensions: 1289689628
Number of sequences better than 0.0: 0
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