BLASTX 7.6.2
Query= UN60349 /QuerySize=671
(670 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q67BJ4|A4GAT_MOUSE Lactosylceramide 4-alpha-galactosyltransfe... 115 4e-025
sp|Q9JI93|A4GAT_RAT Lactosylceramide 4-alpha-galactosyltransfera... 114 5e-025
sp|Q9N291|A4GAT_PANTR Lactosylceramide 4-alpha-galactosyltransfe... 113 1e-024
sp|Q9N289|A4GAT_PONPY Lactosylceramide 4-alpha-galactosyltransfe... 112 2e-024
sp|Q9NPC4|A4GAT_HUMAN Lactosylceramide 4-alpha-galactosyltransfe... 112 2e-024
sp|Q9N290|A4GAT_GORGO Lactosylceramide 4-alpha-galactosyltransfe... 112 3e-024
>sp|Q67BJ4|A4GAT_MOUSE Lactosylceramide 4-alpha-galactosyltransferase OS=Mus
musculus GN=A4galt PE=2 SV=1
Length = 359
Score = 115 bits (286), Expect = 4e-025
Identities = 71/198 (35%), Positives = 107/198 (54%), Gaps = 24/198 (12%)
Frame = +2
Query: 2 RRMFSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRR 181
R + P +P+ LS+ R+ LL+KFGGIYLDTD I+LK L NL N +G Q+ R
Sbjct: 169 RHRWEPYQLPV---LSDASRIALLWKFGGIYLDTDFIVLKNLLNLTNTLGIQS------R 219
Query: 182 WSGLNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSS 349
+ LN A L F++ H L + +F +NG WGH GP L++RV ++ ++ S +
Sbjct: 220 YV-LNGAFLAFERKHEFLALCLHDFVANYNGWIWGHQGPQLLTRVFKKWCSIQSLEKSHA 278
Query: 350 DLGFSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKL 529
G + LPP AFYP+ W ++ D S + L L + AVH+WN++S+
Sbjct: 279 CRGVTALPPEAFYPIPWQNWKKYFE--------DISPEELTQLLNATYAVHVWNKKSQGT 330
Query: 530 RIEEGS--IIQQLMSDSC 577
+E S ++ QL + C
Sbjct: 331 HLEATSKALLAQLHARYC 348
>sp|Q9JI93|A4GAT_RAT Lactosylceramide 4-alpha-galactosyltransferase OS=Rattus
norvegicus GN=A4galt PE=1 SV=1
Length = 360
Score = 114 bits (285), Expect = 5e-025
Identities = 71/195 (36%), Positives = 108/195 (55%), Gaps = 24/195 (12%)
Frame = +2
Query: 11 FSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRRWSG 190
+ P ++P+ LS+ R+ LL+KFGGIYLDTD I+LK L NL N++G Q+ R+
Sbjct: 173 WEPYLLPV---LSDASRIALLWKFGGIYLDTDFIVLKNLRNLTNMLGIQS------RYV- 222
Query: 191 LNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSSDLG 358
LN A L F++ H L I +F +NG WGH GP L++RV ++ ++ S + G
Sbjct: 223 LNGAFLAFERKHEFLALCIRDFVAHYNGWIWGHQGPQLLTRVFKKWCSIHSLKESRACRG 282
Query: 359 FSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKLRIE 538
+ LPP AFYP+ W ++ D S + L L + AVH+WN++S+ +E
Sbjct: 283 VTALPPEAFYPIPWQNWKKYFE--------DVSPEELAQLLNATYAVHVWNKKSQGTHLE 334
Query: 539 EGS--IIQQLMSDSC 577
S ++ QL + C
Sbjct: 335 ATSRALLAQLHARYC 349
>sp|Q9N291|A4GAT_PANTR Lactosylceramide 4-alpha-galactosyltransferase OS=Pan
troglodytes GN=A4GALT PE=3 SV=1
Length = 353
Score = 113 bits (282), Expect = 1e-024
Identities = 70/195 (35%), Positives = 109/195 (55%), Gaps = 24/195 (12%)
Frame = +2
Query: 11 FSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRRWSG 190
+ P ++P+ LS+ R+ L++KFGGIYLDTD I+LK L NL NV+G Q+ R+
Sbjct: 166 WEPYLLPV---LSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQS------RYV- 215
Query: 191 LNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSSDLG 358
LN A L F++ H + + +F +NG WGH GP L++RV ++ +++ S S G
Sbjct: 216 LNGAFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRSCRG 275
Query: 359 FSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKLRIE 538
+ LPP AFYP+ W ++ D + + L L + AVH+WN++S+ R E
Sbjct: 276 VTTLPPEAFYPIPWQDWKKYFE--------DINPEELPRLLSATYAVHVWNKKSQGTRFE 327
Query: 539 EGS--IIQQLMSDSC 577
S ++ QL + C
Sbjct: 328 ATSRALLAQLHARYC 342
>sp|Q9N289|A4GAT_PONPY Lactosylceramide 4-alpha-galactosyltransferase (Fragment)
OS=Pongo pygmaeus GN=A4GALT PE=3 SV=1
Length = 218
Score = 112 bits (280), Expect = 2e-024
Identities = 70/195 (35%), Positives = 108/195 (55%), Gaps = 24/195 (12%)
Frame = +2
Query: 11 FSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRRWSG 190
+ P ++P+ LS+ R+ L++KFGGIYLDTD I+LK L NL NV+G Q+ R+
Sbjct: 31 WEPYLLPV---LSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQS------RYV- 80
Query: 191 LNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSSDLG 358
LN A L F + H + + +F +NG WGH GP L++RV ++ +++ S + G
Sbjct: 81 LNGAFLAFQRRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRG 140
Query: 359 FSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKLRIE 538
+ LPP AFYP+ W ++ D S + L L + AVH+WN++S+ R E
Sbjct: 141 VTTLPPEAFYPIPWQDWKKYFE--------DISPEELPRLLNATYAVHVWNKKSQGTRFE 192
Query: 539 EGS--IIQQLMSDSC 577
S ++ QL + C
Sbjct: 193 ATSRALLAQLHARYC 207
>sp|Q9NPC4|A4GAT_HUMAN Lactosylceramide 4-alpha-galactosyltransferase OS=Homo
sapiens GN=A4GALT PE=2 SV=1
Length = 353
Score = 112 bits (279), Expect = 2e-024
Identities = 69/195 (35%), Positives = 109/195 (55%), Gaps = 24/195 (12%)
Frame = +2
Query: 11 FSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRRWSG 190
+ P ++P+ LS+ R+ L++KFGGIYLDTD I+LK L NL NV+G Q+ R+
Sbjct: 166 WEPYLLPV---LSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQS------RYV- 215
Query: 191 LNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSSDLG 358
LN A L F++ H + + +F +NG WGH GP L++RV ++ +++ S + G
Sbjct: 216 LNGAFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRG 275
Query: 359 FSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKLRIE 538
+ LPP AFYP+ W ++ D + + L L + AVH+WN++S+ R E
Sbjct: 276 VTTLPPEAFYPIPWQDWKKYFE--------DINPEELPRLLSATYAVHVWNKKSQGTRFE 327
Query: 539 EGS--IIQQLMSDSC 577
S ++ QL + C
Sbjct: 328 ATSRALLAQLHARYC 342
>sp|Q9N290|A4GAT_GORGO Lactosylceramide 4-alpha-galactosyltransferase (Fragment)
OS=Gorilla gorilla gorilla GN=A4GALT PE=3 SV=1
Length = 327
Score = 112 bits (278), Expect = 3e-024
Identities = 69/195 (35%), Positives = 109/195 (55%), Gaps = 24/195 (12%)
Frame = +2
Query: 11 FSPGVIPLEQNLSNLLRLVLLYKFGGIYLDTDVIILKPLTNLHNVIGAQTVDPVTRRWSG 190
+ P ++P+ LS+ R+ L++KFGGIYLDTD I+LK L NL NV+G Q+ R+
Sbjct: 140 WEPYLLPV---LSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQS------RYV- 189
Query: 191 LNNAVLIFDKNHPLLKSFIDEFSRTFNGNKWGHNGPYLVSRVVARF----NVSSSSSDLG 358
LN A L F++ H + + +F +NG WGH GP L++RV ++ +++ S + G
Sbjct: 190 LNGAFLAFERXHEFMALCMXDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRG 249
Query: 359 FSVLPPSAFYPVDWTRISGFYRPSVNERETDWSGKRLMHLRKHSLAVHLWNRESKKLRIE 538
+ LPP AFYP+ W ++ D + + L L + AVH+WN++S+ R E
Sbjct: 250 VTTLPPEAFYPIPWQDWKKYFE--------DINPEELPRLFSATYAVHVWNKKSQGTRFE 301
Query: 539 EGS--IIQQLMSDSC 577
S ++ QL + C
Sbjct: 302 ATSRALLAQLHARYC 316
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 211,499,373,720
Number of Sequences: 518415
Number of Extensions: 211499373720
Number of Successful Extensions: 1295646188
Number of sequences better than 0.0: 0
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