BLASTX 7.6.2
Query= UN60713 /QuerySize=752
(751 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member ... 75 5e-013
sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13 OS=S... 69 2e-011
sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member ... 68 5e-011
sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens G... 65 3e-010
sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus G... 65 4e-010
sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=... 65 6e-010
sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus G... 65 6e-010
sp|A6QP05|DHR12_BOVIN Dehydrogenase/reductase SDR family member ... 63 2e-009
sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens G... 61 8e-009
sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens G... 58 5e-008
sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus G... 57 9e-008
sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member ... 57 1e-007
>sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member on chromosome X
homolog OS=Mus musculus GN=Dhrsx PE=2 SV=2
Length = 335
Score = 75 bits (182), Expect = 5e-013
Identities = 43/125 (34%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
AT+G+G++TA L+R G +V+ G H + ++ IR + + +D++S SV
Sbjct: 51 ATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEMGSDRAHFLPLDLASLASVR 110
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F + L + LLVNNAG++ T +GF+R + N++G F LT LLLP
Sbjct: 111 GFARDFQA------LGLPLHLLVNNAGVMLEPRAETEDGFERHLGVNFLGHFLLTLLLLP 164
Query: 731 LLRNS 745
LR S
Sbjct: 165 ALRAS 169
>sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13
OS=Schizosaccharomyces pombe GN=SPCC736.13 PE=2 SV=1
Length = 339
Score = 69 bits (168), Expect = 2e-011
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
++ G+G TA L+RKG + L GR+ K + +I + + ++++ +D+ F+SV
Sbjct: 50 SSGGIGYVTALELARKGAKVYLAGRNEEKYQKVMKQIHDEVRHSKIRFLRLDLLDFESVY 109
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
+ + E ++ + + +LVNNAGI+ T +G++ + TNY+ + T+LLLP
Sbjct: 110 Q---AAESFIAKEE---KLHILVNNAGIMNPPFELTKDGYELQIQTNYLSHYLFTELLLP 163
Query: 731 LLRNS 745
LR +
Sbjct: 164 TLRRT 168
>sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X
OS=Homo sapiens GN=DHRSX PE=2 SV=2
Length = 330
Score = 68 bits (165), Expect = 5e-011
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 6/124 (4%)
Frame = +2
Query: 374 TSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVSK 553
T G+G +TA L+R G ++++ G + + +++I+++ + +++ D++S S+ +
Sbjct: 52 TDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDLASMTSIRQ 111
Query: 554 FRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLPL 733
F + + + +L+NNAG++ R T +GF+ NY+G F LT LLL
Sbjct: 112 FVQKFKMKKI------PLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLLDT 165
Query: 734 LRNS 745
L+ S
Sbjct: 166 LKES 169
>sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens GN=RDH13 PE=1
SV=2
Length = 331
Score = 65 bits (158), Expect = 3e-010
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+R+G I+L R +IR + + + A +D++S +S+
Sbjct: 46 ANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIR 105
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
+F + + + +L+NNAG++ T +GF+ N++G F LT LLL
Sbjct: 106 EFAAKI------IEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLD 159
Query: 731 LLRNS 745
L+ S
Sbjct: 160 KLKAS 164
>sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus GN=Rdh12 PE=2
SV=1
Length = 316
Score = 65 bits (157), Expect = 4e-010
Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+R+G + + R +EIR K++Q+ ++D+S +S+
Sbjct: 47 ANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIR 106
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F E++L + + +L+NNAG++ T +GF+ N++G F LT LLL
Sbjct: 107 AF---AERFLAE---EKKLHILINNAGVMMCPYSKTTDGFETHFGVNHLGHFLLTYLLLE 160
Query: 731 LLRNS 745
L+ S
Sbjct: 161 RLKES 165
>sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=RDH12 PE=2
SV=1
Length = 316
Score = 65 bits (156), Expect = 6e-010
Identities = 39/125 (31%), Positives = 68/125 (54%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+R+G + + R +EI+ K++Q+ ++D+S +S+
Sbjct: 47 ANTGIGKETARELARRGARVYIACRDVLKGESAASEIQADTKNSQVLVRKLDLSDTKSIR 106
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F E +L + + +L+NNAG++ T +GF+ +A N++G F LT LLL
Sbjct: 107 AF---AEGFLAE---EKQLHILINNAGVMLCPYSKTADGFETHLAVNHLGHFLLTHLLLG 160
Query: 731 LLRNS 745
L+ S
Sbjct: 161 RLKES 165
>sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus GN=Rdh13 PE=2
SV=1
Length = 334
Score = 65 bits (156), Expect = 6e-010
Identities = 36/125 (28%), Positives = 65/125 (52%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+++G ++L R +IR + + +++A +D++S +S+
Sbjct: 46 ANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGETLNPRVRAERLDLASLKSIR 105
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
+F + + + +LVNNA ++ T +GF+ NY+G F LT LLL
Sbjct: 106 EFARKVIK------EEERVDILVNNAAVMRCPHWTTEDGFEMQFGVNYLGHFLLTNLLLD 159
Query: 731 LLRNS 745
L+ S
Sbjct: 160 KLKAS 164
>sp|A6QP05|DHR12_BOVIN Dehydrogenase/reductase SDR family member 12 OS=Bos
taurus GN=DHRS12 PE=2 SV=1
Length = 317
Score = 63 bits (152), Expect = 2e-009
Identities = 38/120 (31%), Positives = 65/120 (54%), Gaps = 7/120 (5%)
Frame = +2
Query: 377 SGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVSKF 556
SG+GKATA ++++G + LV R AEI +++ + + VD+S +SV KF
Sbjct: 50 SGIGKATAMEIAKRGGTVHLVCRDHSRAEGAKAEIIRESGNQNIFLHIVDLSLPKSVWKF 109
Query: 557 RNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLPLL 736
+ +Q ++ +L+NNAG + T +G ++ ATN +G + LT L+P+L
Sbjct: 110 VENFKQ-------EHTLNVLINNAGCMVNKRELTEDGLEKNFATNTLGVYVLTTALIPVL 162
>sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens GN=RDH12 PE=1
SV=3
Length = 316
Score = 61 bits (146), Expect = 8e-009
Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+ +G + + R +EIR K++Q+ ++D+S +S+
Sbjct: 47 ANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIR 106
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F E +L + + +L+NNAG++ T +GF+ + N++G F LT LLL
Sbjct: 107 AF---AEGFLAE---EKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLE 160
Query: 731 LLRNS 745
L+ S
Sbjct: 161 RLKVS 165
>sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens GN=RDH11 PE=1
SV=2
Length = 318
Score = 58 bits (139), Expect = 5e-008
Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+++G + L R EI+ + Q+ ++D+S +S+
Sbjct: 49 ANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIR 108
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F L + H + +L+NNAG++ T +GF+ + N++G F LT LLL
Sbjct: 109 AFAKG----FLAEEKH--LHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLE 162
Query: 731 LLRNS 745
L+ S
Sbjct: 163 KLKES 167
>sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus GN=Rdh11 PE=2
SV=2
Length = 316
Score = 57 bits (137), Expect = 9e-008
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Frame = +2
Query: 371 ATSGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVS 550
A +G+GK TA L+++G + L R EI+ ++Q+ ++D++ +S+
Sbjct: 46 ANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIR 105
Query: 551 KFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLP 730
F L + H + LL+NNAG++ T +GF+ + N++G F LT LLL
Sbjct: 106 AFAKD----FLAEEKH--LHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLE 159
Query: 731 LLRNS 745
L+ S
Sbjct: 160 KLKES 164
>sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member 12 OS=Homo
sapiens GN=DHRS12 PE=2 SV=2
Length = 317
Score = 57 bits (136), Expect = 1e-007
Identities = 34/120 (28%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Frame = +2
Query: 377 SGLGKATAFALSRKGFYIVLVGRSSHLLSKTLAEIRKQNKDAQLKAFEVDISSFQSVSKF 556
SG+GKATA ++++G + LV R EI +++ + + VD+S + + KF
Sbjct: 50 SGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKF 109
Query: 557 RNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPTIEGFDRMMATNYIGAFSLTKLLLPLL 736
+ +Q + +L+NNAG + T +G ++ A N +G + LT L+P+L
Sbjct: 110 VENFKQ-------EHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVL 162
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 212,551,580,446
Number of Sequences: 518415
Number of Extensions: 212551580446
Number of Successful Extensions: 1307607611
Number of sequences better than 0.0: 0
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