BLASTX 7.6.2
Query= UN61218 /QuerySize=672
(671 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6NYY9|TMM49_DANRE Transmembrane protein 49 OS=Danio rerio GN... 98 5e-020
sp|Q0VCK9|TMM49_BOVIN Transmembrane protein 49 OS=Bos taurus GN=... 94 5e-019
sp|Q5R9K4|TMM49_PONAB Transmembrane protein 49 OS=Pongo abelii G... 94 9e-019
sp|Q91ZQ0|TMM49_RAT Transmembrane protein 49 OS=Rattus norvegicu... 94 9e-019
sp|Q96GC9|TMM49_HUMAN Transmembrane protein 49 OS=Homo sapiens G... 93 1e-018
sp|Q99KU0|TMM49_MOUSE Transmembrane protein 49 OS=Mus musculus G... 93 1e-018
sp|Q68EQ9|TMM49_XENTR Transmembrane protein 49 OS=Xenopus tropic... 86 2e-016
sp|Q54NL4|TMM49_DICDI Transmembrane protein 49 homolog OS=Dictyo... 84 9e-016
sp|Q6INE8|TMM49_XENLA Transmembrane protein 49 OS=Xenopus laevis... 83 1e-015
>sp|Q6NYY9|TMM49_DANRE Transmembrane protein 49 OS=Danio rerio GN=tmem49 PE=2
SV=1
Length = 406
Score = 98 bits (242), Expect = 5e-020
Identities = 52/142 (36%), Positives = 81/142 (57%), Gaps = 1/142 (0%)
Frame = +2
Query: 116 SSSSSDVAISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFLL 295
+ SS+D ++ ++ +E +L L +PF TL+ F T + +K L G L
Sbjct: 22 NGSSTDSSLRERKQLDREERLSLVLWKRPFITLQYFFLETAITLKEWTWKLWQRRGVVFL 81
Query: 296 VTTLLVVFGVLLATVDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLGP 475
L +F L +++G H ++V+ L + + +W+ LG+ SS+GLG+GLHTF+LYLGP
Sbjct: 82 TVVLFSLFS-LAYSIEGAHQEYVQHLEKKFLWCAYWVGLGILSSVGLGTGLHTFLLYLGP 140
Query: 476 HIALFTLKATQCGRVDLKSAPY 541
HIA TL A +CG V+ PY
Sbjct: 141 HIASVTLAAYECGSVNFPEPPY 162
>sp|Q0VCK9|TMM49_BOVIN Transmembrane protein 49 OS=Bos taurus GN=TMEM49 PE=2
SV=1
Length = 406
Score = 94 bits (233), Expect = 5e-019
Identities = 51/137 (37%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 137 AISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFLLVTTLLVV 316
+++ + + +E +N+ L QP TL+ F T + +K S L +V + L++
Sbjct: 29 SVNEKKRRDREERQNIVLWRQPLITLQYFSLETLVILKEWTSKLWHRQS---IVVSFLLL 85
Query: 317 FGVLLAT--VDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLGPHIALF 490
VL AT V+G H ++V+ + + +WI LG+ SS+GLG+GLHTF+LYLGPHIA
Sbjct: 86 LAVLTATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASV 145
Query: 491 TLKATQCGRVDLKSAPY 541
TL A +C V+ PY
Sbjct: 146 TLAAYECNSVNFPEPPY 162
>sp|Q5R9K4|TMM49_PONAB Transmembrane protein 49 OS=Pongo abelii GN=TMEM49 PE=2
SV=1
Length = 406
Score = 94 bits (231), Expect = 9e-019
Identities = 50/137 (36%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 137 AISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFLLVTTLLVV 316
+++ + + +E +N+ L QP TL+ F + +K S L +V + L++
Sbjct: 29 SVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQS---IVVSFLLL 85
Query: 317 FGVLLAT--VDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLGPHIALF 490
VL+AT V+G H ++V+ + + +WI LG+ SS+GLG+GLHTF+LYLGPHIA
Sbjct: 86 LAVLIATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASV 145
Query: 491 TLKATQCGRVDLKSAPY 541
TL A +C V+ PY
Sbjct: 146 TLAAYECNSVNFPEPPY 162
>sp|Q91ZQ0|TMM49_RAT Transmembrane protein 49 OS=Rattus norvegicus GN=Tmem49
PE=2 SV=1
Length = 406
Score = 94 bits (231), Expect = 9e-019
Identities = 51/153 (33%), Positives = 84/153 (54%), Gaps = 5/153 (3%)
Frame = +2
Query: 89 GSAAAATSSSSSSSDVAISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYL 268
G+ + + S + +++ + + +E +N+ L QP TL+ F T + +K S L
Sbjct: 13 GAMSKEQHNGSFTDPSSVNEKKRRDREERQNIVLWRQPLITLQYFSLETLVVLKEWTSKL 72
Query: 269 LSHGGWFLLVTTLLVVFGVLLAT--VDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGS 442
+V + ++ L+AT V+G H ++V+ + + +WI LG+ SS+GLG+
Sbjct: 73 WHRQS---MVVSFFLLLAALVATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGT 129
Query: 443 GLHTFVLYLGPHIALFTLKATQCGRVDLKSAPY 541
GLHTF+LYLGPHIA TL A +C V+ PY
Sbjct: 130 GLHTFLLYLGPHIASVTLAAYECNSVNFPEPPY 162
>sp|Q96GC9|TMM49_HUMAN Transmembrane protein 49 OS=Homo sapiens GN=TMEM49 PE=2
SV=1
Length = 406
Score = 93 bits (230), Expect = 1e-018
Identities = 50/137 (36%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 137 AISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFLLVTTLLVV 316
+++ + + +E +N+ L QP TL+ F + +K S L +V + L++
Sbjct: 29 SVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQS---IVVSFLLL 85
Query: 317 FGVLLAT--VDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLGPHIALF 490
VL+AT V+G H ++V+ + + +WI LG+ SS+GLG+GLHTF+LYLGPHIA
Sbjct: 86 LAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASV 145
Query: 491 TLKATQCGRVDLKSAPY 541
TL A +C V+ PY
Sbjct: 146 TLAAYECNSVNFPEPPY 162
>sp|Q99KU0|TMM49_MOUSE Transmembrane protein 49 OS=Mus musculus GN=Tmem49 PE=2
SV=2
Length = 406
Score = 93 bits (230), Expect = 1e-018
Identities = 51/145 (35%), Positives = 81/145 (55%), Gaps = 5/145 (3%)
Frame = +2
Query: 113 SSSSSSDVAISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFL 292
+ S + ++ + + +E +N+ L QP TL+ F T + +K S L
Sbjct: 21 NGSLTDPSSVHEKKRRDREERQNIVLWRQPLITLQYFSLETLVVLKEWTSKLWHRQS--- 77
Query: 293 LVTTLLVVFGVLLAT--VDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLY 466
+V + L++ L+AT V+G H ++V+ + + +WI LG+ SS+GLG+GLHTF+LY
Sbjct: 78 IVVSFLLLLAALVATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLY 137
Query: 467 LGPHIALFTLKATQCGRVDLKSAPY 541
LGPHIA TL A +C V+ PY
Sbjct: 138 LGPHIASVTLAAYECNSVNFPEPPY 162
>sp|Q68EQ9|TMM49_XENTR Transmembrane protein 49 OS=Xenopus tropicalis GN=tmem49
PE=2 SV=1
Length = 406
Score = 86 bits (210), Expect = 2e-016
Identities = 43/134 (32%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Frame = +2
Query: 140 ISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFLLVTTLLVVF 319
+S + + +E +++ L +P TL+ F+ + +K S L H ++ LL+
Sbjct: 30 LSDRKSRDREERQSIVLWRKPLITLQYFILEVLITLK-DWSIRLWHRRMMVVSVLLLLAV 88
Query: 320 GVLLATVDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLGPHIALFTLK 499
++ ++G H ++V+ + + + +W+ LG+ SS+GLG+GLHTF+LYLGPHIA T+
Sbjct: 89 LSVVYYIEGTHQQYVQYVEKKCLWCAYWVGLGILSSVGLGTGLHTFLLYLGPHIASVTIA 148
Query: 500 ATQCGRVDLKSAPY 541
A +C V+ PY
Sbjct: 149 AYECNSVNFPEPPY 162
>sp|Q54NL4|TMM49_DICDI Transmembrane protein 49 homolog OS=Dictyostelium
discoideum GN=tmem49 PE=3 SV=1
Length = 403
Score = 84 bits (205), Expect = 9e-016
Identities = 50/137 (36%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +2
Query: 113 SSSSSSDVAISALREKHEKEVENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWFL 292
S+ + I L E+ EK +N+ L P T K F+ + I Y + + L
Sbjct: 10 SNEKDIQLRIQQLEERKEKR-KNVKLLFSPIKTTKYFLYILKDTLVSGIRYFQTR-PFLL 67
Query: 293 LVTTLLVVFGVLLATVDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYLG 472
L + V G H K++ + + + +WW+ LGV SSIGLG+GLHTFVLYLG
Sbjct: 68 FFIALFASLTFIAVYVPGEHQKYMGKYSDLISDCIWWVGLGVLSSIGLGTGLHTFVLYLG 127
Query: 473 PHIALFTLKATQCGRVD 523
PHIA TL AT+ V+
Sbjct: 128 PHIAKVTLAATEWNSVN 144
>sp|Q6INE8|TMM49_XENLA Transmembrane protein 49 OS=Xenopus laevis GN=tmem49 PE=2
SV=1
Length = 406
Score = 83 bits (204), Expect = 1e-015
Identities = 45/144 (31%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = +2
Query: 113 SSSSSSDVAISALREKHEKEV-ENLTLTSQPFYTLKLFVEATFLYIKRSISYLLSHGGWF 289
++ S D + R++ ++E +++ L +P TL+ F+ + +K S L H
Sbjct: 20 NNGSFQDPSFMCNRKRRDREERQSIVLWRKPLITLQYFILEVLINLK-EWSVRLWHRRMM 78
Query: 290 LLVTTLLVVFGVLLATVDGPHGKHVEELLEYVRYSLWWIALGVASSIGLGSGLHTFVLYL 469
++ LL+ + ++G H + V+ + + + +W+ LG+ SS+GLG+GLHTF+LYL
Sbjct: 79 VVSVLLLLAVLSVAYYIEGEHQQCVQYIEKKCLWCAYWVGLGILSSVGLGTGLHTFLLYL 138
Query: 470 GPHIALFTLKATQCGRVDLKSAPY 541
GPHIA T+ A +C V+ PY
Sbjct: 139 GPHIASVTIAAYECNSVNFPEPPY 162
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 215,453,981,912
Number of Sequences: 518415
Number of Extensions: 215453981912
Number of Successful Extensions: 1318477742
Number of sequences better than 0.0: 0
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