BLASTX 7.6.2
Query= UN62337 /QuerySize=826
(825 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member ... 78 7e-014
sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member ... 75 6e-013
sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gall... 57 1e-007
sp|Q60V51|LE767_CAEBR Putative steroid dehydrogenase let-767 OS=... 54 9e-007
sp|Q0CY11|MKAR_ASPTN 3-ketoacyl-CoA reductase OS=Aspergillus ter... 54 1e-006
sp|Q17704|STDH3_CAEEL Putative steroid dehydrogenase 3 OS=Caenor... 53 3e-006
sp|A4QTE3|MKAR_MAGGR 3-ketoacyl-CoA reductase OS=Magnaporthe gri... 52 3e-006
sp|Q09517|LE767_CAEEL Putative steroid dehydrogenase let-767 OS=... 52 4e-006
sp|Q17703|STDH1_CAEEL Putative steroid dehydrogenase 1 OS=Caenor... 52 4e-006
sp|O17795|STDH2_CAEEL Putative steroid dehydrogenase 2 OS=Caenor... 52 4e-006
>sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member on chromosome X
homolog OS=Mus musculus GN=Dhrsx PE=2 SV=2
Length = 335
Score = 78 bits (190), Expect = 7e-014
Identities = 42/131 (32%), Positives = 71/131 (54%), Gaps = 6/131 (4%)
Frame = +2
Query: 314 ICVITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDIS 493
+ ++TGAT+G+G++TA L+R G VV+ G H + ++ I+ + + +D++
Sbjct: 45 VAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEMGSDRAHFLPLDLA 104
Query: 494 SFQSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPIIEGFDRMMATNYMGAFSL 673
S SV F + L + LLVNNAG++ +GF+R + N++G F L
Sbjct: 105 SLASVRGFARDFQA------LGLPLHLLVNNAGVMLEPRAETEDGFERHLGVNFLGHFLL 158
Query: 674 TKLLLPLLKTA 706
T LLLP L+ +
Sbjct: 159 TLLLLPALRAS 169
>sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X
OS=Homo sapiens GN=DHRSX PE=2 SV=2
Length = 330
Score = 75 bits (182), Expect = 6e-013
Identities = 37/129 (28%), Positives = 71/129 (55%), Gaps = 6/129 (4%)
Frame = +2
Query: 314 ICVITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDIS 493
+ ++TG T G+G +TA L+R G +V++ G + + +++IK++ + +++ D++
Sbjct: 45 VAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDLA 104
Query: 494 SFQSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPIIEGFDRMMATNYMGAFSL 673
S S+ +F + + + +L+NNAG++ R +GF+ NY+G F L
Sbjct: 105 SMTSIRQFVQKFKMKKI------PLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLL 158
Query: 674 TKLLLPLLK 700
T LLL LK
Sbjct: 159 TNLLLDTLK 167
>sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gallus gallus
GN=WWOX PE=2 SV=2
Length = 414
Score = 57 bits (137), Expect = 1e-007
Identities = 39/145 (26%), Positives = 73/145 (50%), Gaps = 6/145 (4%)
Frame = +2
Query: 314 ICVITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDIS 493
+ +ITGA SG+G TA + + G YV+L R+ + + I ++ A+++A +D++
Sbjct: 126 VIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKAKVEAMTLDLA 185
Query: 494 SFQSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPIIEGFDRMMATNYMGAFSL 673
S +SV F + + + + +LV NA I +S +G + N++G F L
Sbjct: 186 SLRSVQNFAEAFK------SKNMPLHILVCNAAIFGSSWCLTEDGLESTFQVNHLGHFYL 239
Query: 674 TKLLLPLLKTALCLHES*CTSFTHR 748
+LL +L+ + +S +HR
Sbjct: 240 VQLLEDILRRSSPARVVVVSSESHR 264
>sp|Q60V51|LE767_CAEBR Putative steroid dehydrogenase let-767 OS=Caenorhabditis
briggsae GN=let-767 PE=3 SV=1
Length = 316
Score = 54 bits (129), Expect = 9e-007
Identities = 34/92 (36%), Positives = 55/92 (59%), Gaps = 6/92 (6%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
VITGAT G+GKA AF L+R+GF V +V R+ L +T EI ++ + +++ D ++
Sbjct: 51 VITGATDGIGKAYAFELARRGFNVFIVSRTQSKLDETKKEILEKYPNIEVRTAAYDFTN- 109
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGI 595
+ S ++N LL++ I +LVNN G+
Sbjct: 110 AAPSGYKN-----LLETLNKVEIGVLVNNVGL 136
>sp|Q0CY11|MKAR_ASPTN 3-ketoacyl-CoA reductase OS=Aspergillus terreus (strain
NIH 2624 / FGSC A1156) GN=ATEG_01423 PE=3 SV=1
Length = 353
Score = 54 bits (128), Expect = 1e-006
Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 11/171 (6%)
Frame = +2
Query: 194 WNFALLSSYFQLLKRRIFGSKSTS-FSSSSSSSSSSSSHRPICVITGATSGLGKATAFAL 370
W +F + + +FG S F S S V+TGA+ GLGK A L
Sbjct: 35 WALIAAGGFFVISRALLFGRVLLSLFVLPGKSLRSFGPKGSWAVVTGASDGLGKEFALQL 94
Query: 371 SRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSFQSVSKFRNSLEQWLLDS 550
+R G+ +VLV R++ L E+ + Q K +D + Q L++ + D
Sbjct: 95 ARAGYNIVLVSRTASKLDTLSDELTSKYPSVQTKVLAMDFARNQDSD--YQKLKELIGDL 152
Query: 551 DLHSSIQLLVNNAGILATSSRPII----EGFDRMMATNYMGAFSLTKLLLP 691
D + +L+NN G P E ++ N MG +T+L++P
Sbjct: 153 D----VAVLINNVGKSHDMPVPFALTSEEEMTDIVTINCMGTLRVTQLVVP 199
>sp|Q17704|STDH3_CAEEL Putative steroid dehydrogenase 3 OS=Caenorhabditis
elegans GN=stdh-3 PE=2 SV=1
Length = 349
Score = 53 bits (125), Expect = 3e-006
Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 6/93 (6%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
VITG T G+GK+ +F L+++GF + +V R+ L +T EI ++ + +++ D ++
Sbjct: 51 VITGGTDGIGKSFSFELAKRGFNIYIVSRTQSKLEQTKKEIMEKYSNVEVRFATFDFTN- 109
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGIL 598
S+S ++ L Q SI +L+NN G+L
Sbjct: 110 PSISDYKKLLSQL-----NEVSIGMLINNVGML 137
>sp|A4QTE3|MKAR_MAGGR 3-ketoacyl-CoA reductase OS=Magnaporthe grisea
GN=MGG_05096 PE=3 SV=1
Length = 331
Score = 52 bits (124), Expect = 3e-006
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 10/130 (7%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
V+TGA+ GLGK A L+ KGF +VLV R+ L + E++ +N + K +D
Sbjct: 60 VVTGASDGLGKEFASQLAAKGFNIVLVSRTESKLKELAKELEAKNGSLKTKVLAMDYE-- 117
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGILATSSRPII----EGFDRMMATNYMGAF 667
Q L Q L D + +L+NN G + P + E ++ N +G
Sbjct: 118 QDNDDDYEKLGQLLSGLD----VAILINNVGRSHSIPVPFLQTPREELQNIVTINCLGTL 173
Query: 668 SLTKLLLPLL 697
T+++ P++
Sbjct: 174 KTTQVVAPIM 183
>sp|Q09517|LE767_CAEEL Putative steroid dehydrogenase let-767 OS=Caenorhabditis
elegans GN=let-767 PE=1 SV=2
Length = 316
Score = 52 bits (123), Expect = 4e-006
Identities = 32/92 (34%), Positives = 54/92 (58%), Gaps = 6/92 (6%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
V+TGAT G+GKA AF L+R+GF V+LV R+ L +T EI ++ +++ D ++
Sbjct: 51 VVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTN- 109
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGI 595
+ S +++ LL + I +L+NN G+
Sbjct: 110 AAPSAYKD-----LLATLNQVEIGVLINNVGM 136
>sp|Q17703|STDH1_CAEEL Putative steroid dehydrogenase 1 OS=Caenorhabditis
elegans GN=stdh-1 PE=2 SV=1
Length = 314
Score = 52 bits (123), Expect = 4e-006
Identities = 32/92 (34%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
V+TGAT G+GK+ +F L+++GF V +V R+ L T EI + + D +++ D ++
Sbjct: 51 VVTGATDGIGKSYSFELAKRGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRFATFDFTN- 109
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGI 595
SVS + LL SI +L+NN G+
Sbjct: 110 PSVSDYEK-----LLSKLNEVSIGILINNVGM 136
>sp|O17795|STDH2_CAEEL Putative steroid dehydrogenase 2 OS=Caenorhabditis
elegans GN=stdh-2 PE=2 SV=1
Length = 315
Score = 52 bits (123), Expect = 4e-006
Identities = 30/92 (32%), Positives = 53/92 (57%), Gaps = 6/92 (6%)
Frame = +2
Query: 320 VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLAEIKKQNKDAQLKAFEVDISSF 499
V+TGAT G+GK+ +F L+R+GF V +V R+ L +T +I ++ D +++ D ++
Sbjct: 51 VVTGATDGIGKSYSFELARRGFNVYIVSRTQSKLEQTKKDILEKQPDIEVRFATYDFTN- 109
Query: 500 QSVSKFRNSLEQWLLDSDLHSSIQLLVNNAGI 595
SV+ + LL S+ +L+NN G+
Sbjct: 110 PSVTDYEK-----LLSKLNEVSVGILINNVGM 136
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 215,991,697,678
Number of Sequences: 518415
Number of Extensions: 215991697678
Number of Successful Extensions: 1324424465
Number of sequences better than 0.0: 0
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