BLASTX 7.6.2
Query= UN66103 /QuerySize=629
(628 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochond... 85 4e-016
sp|Q29448|HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, mitochond... 70 1e-011
sp|P97519|HMGCL_RAT Hydroxymethylglutaryl-CoA lyase, mitochondri... 68 5e-011
sp|A8WG57|HMGC2_DANRE Probable 3-hydroxymethyl-3-methylglutaryl-... 67 6e-011
sp|P38060|HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochond... 67 6e-011
sp|Q8TB92|HMGC2_HUMAN Probable 3-hydroxymethyl-3-methylglutaryl-... 67 8e-011
sp|Q8JZS7|HMGC2_MOUSE Probable 3-hydroxymethyl-3-methylglutaryl-... 65 2e-010
sp|P35914|HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, mitochond... 64 9e-010
sp|Q8HXZ6|HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, mitochond... 64 9e-010
sp|Q5R9E1|HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, mitochond... 64 9e-010
sp|P35915|HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase OS=Gallus ... 63 1e-009
>sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial
OS=Arabidopsis thaliana GN=HMGCL PE=1 SV=2
Length = 468
Score = 85 bits (208), Expect = 4e-016
Identities = 41/49 (83%), Positives = 47/49 (95%)
Frame = +1
Query: 481 QLLREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
++ + +PKFVKIVEVGPRDGLQNEKNIVPTSVKVELI+RLVS+GLPVVE
Sbjct: 159 KISKGIPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVE 207
>sp|Q29448|HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Bos
taurus GN=HMGCL PE=2 SV=2
Length = 325
Score = 70 bits (169), Expect = 1e-011
Identities = 35/43 (81%), Positives = 37/43 (86%)
Frame = +1
Query: 499 PKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
PK VKIVEVGPRDGLQNEKNIVPT VK++LI L AGLPVVE
Sbjct: 30 PKQVKIVEVGPRDGLQNEKNIVPTPVKIKLIDMLSEAGLPVVE 72
>sp|P97519|HMGCL_RAT Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus
norvegicus GN=Hmgcl PE=2 SV=1
Length = 325
Score = 68 bits (164), Expect = 5e-011
Identities = 33/44 (75%), Positives = 38/44 (86%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+PK VKIVEVGPRDGLQNEK+IVPT VK++LI L AGLPV+E
Sbjct: 29 LPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIE 72
>sp|A8WG57|HMGC2_DANRE Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Danio rerio GN=hmgcll1 PE=2 SV=1
Length = 335
Score = 67 bits (163), Expect = 6e-011
Identities = 36/67 (53%), Positives = 47/67 (70%), Gaps = 1/67 (1%)
Frame = +1
Query: 430 TLSKHFHTLPHSLNKQQ-QLLREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVS 606
T + + LP L +++ L ++P +VKIVEVGPRDGLQNEK IVPT VK++LI L
Sbjct: 16 TFLRDYPWLPRLLWEEKCSELPKLPVYVKIVEVGPRDGLQNEKEIVPTEVKIQLIDLLSQ 75
Query: 607 AGLPVVE 627
GLPV+E
Sbjct: 76 TGLPVIE 82
>sp|P38060|HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Mus
musculus GN=Hmgcl PE=1 SV=1
Length = 325
Score = 67 bits (163), Expect = 6e-011
Identities = 33/44 (75%), Positives = 37/44 (84%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+PK VKIVEVGPRDGLQNEK+IVPT VK+ LI L AGLPV+E
Sbjct: 29 LPKQVKIVEVGPRDGLQNEKSIVPTPVKIRLIDMLSEAGLPVIE 72
>sp|Q8TB92|HMGC2_HUMAN Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Homo sapiens GN=HMGCLL1 PE=2 SV=3
Length = 370
Score = 67 bits (162), Expect = 8e-011
Identities = 32/47 (68%), Positives = 37/47 (78%)
Frame = +1
Query: 487 LREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
L +P+FVKIVEVGPRDGLQNEK IVPT +K+E I RL GL V+E
Sbjct: 71 LSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIE 117
>sp|Q8JZS7|HMGC2_MOUSE Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Mus musculus GN=Hmgcll1 PE=2 SV=1
Length = 343
Score = 65 bits (158), Expect = 2e-010
Identities = 30/44 (68%), Positives = 37/44 (84%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+P++VKIVEVGPRDGLQNEK IVPT +K+ELI +L GL V+E
Sbjct: 44 LPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIE 87
>sp|P35914|HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo
sapiens GN=HMGCL PE=1 SV=2
Length = 325
Score = 64 bits (153), Expect = 9e-010
Identities = 32/44 (72%), Positives = 36/44 (81%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+PK VKIVEVGPRDGLQNEKNIV T VK++LI L AGL V+E
Sbjct: 29 LPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIE 72
>sp|Q8HXZ6|HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Macaca
fascicularis GN=HMGCL PE=2 SV=1
Length = 325
Score = 64 bits (153), Expect = 9e-010
Identities = 32/44 (72%), Positives = 36/44 (81%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+PK VKIVEVGPRDGLQNEKNIV T VK++LI L AGL V+E
Sbjct: 29 LPKQVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIE 72
>sp|Q5R9E1|HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Pongo
abelii GN=HMGCL PE=2 SV=1
Length = 325
Score = 64 bits (153), Expect = 9e-010
Identities = 32/44 (72%), Positives = 36/44 (81%)
Frame = +1
Query: 496 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
+PK VKIVEVGPRDGLQNEKNIV T VK++LI L AGL V+E
Sbjct: 29 LPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIE 72
>sp|P35915|HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase OS=Gallus gallus GN=HMGCL
PE=1 SV=1
Length = 298
Score = 63 bits (152), Expect = 1e-009
Identities = 29/43 (67%), Positives = 35/43 (81%)
Frame = +1
Query: 499 PKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVE 627
P+ VK+VEVGPRDGLQNEK++VPT VK+ LI L GLPV+E
Sbjct: 3 PQRVKVVEVGPRDGLQNEKSVVPTPVKIRLIDMLSETGLPVIE 45
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 224,586,243,839
Number of Sequences: 518415
Number of Extensions: 224586243839
Number of Successful Extensions: 1413644693
Number of sequences better than 0.0: 0
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