BLASTX 7.6.2
Query= UN66211 /QuerySize=745
(744 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 230 1e-059
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 218 5e-056
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 217 7e-056
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 155 4e-037
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 155 4e-037
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 137 1e-031
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 134 6e-031
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 121 7e-027
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 119 3e-026
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 230 bits (585), Expect = 1e-059
Identities = 113/127 (88%), Positives = 118/127 (92%), Gaps = 4/127 (3%)
Frame = +1
Query: 1 EEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 180
+E EGI L QQRYPWEGS+RDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV
Sbjct: 95 QEGEEGIVL----QQRYPWEGSERDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 150
Query: 181 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEG 360
LREGTKKTVFVNFMDLCKTMHRQPDHVM +LLAELGTSGSLDGQQRLVVKG FAPKNFEG
Sbjct: 151 LREGTKKTVFVNFMDLCKTMHRQPDHVMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEG 210
Query: 361 ILRRYVS 381
ILRRY++
Sbjct: 211 ILRRYIT 217
Score = 99 bits (246), Expect = 2e-020
Identities = 48/67 (71%), Positives = 53/67 (79%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F +N + +L +YVICLGCKSPDTILSKENRLFFLRCEKCGS RSVA IK GFVA
Sbjct: 202 RFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLFFLRCEKCGSQRSVAPIKTGFVA 261
Query: 601 RVGRTKT 621
RV R KT
Sbjct: 262 RVSRRKT 268
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 218 bits (553), Expect = 5e-056
Identities = 106/128 (82%), Positives = 115/128 (89%), Gaps = 2/128 (1%)
Frame = +1
Query: 1 EEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 180
+E EGI L Q YPWEG+DRDY YDELLGRVFNILRENNP+LAGDRRRTVMRPPQV
Sbjct: 93 DEQGEGIVLGGATQ--YPWEGTDRDYKYDELLGRVFNILRENNPDLAGDRRRTVMRPPQV 150
Query: 181 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEG 360
LREGTKKTVFVNFMDLCKTMHRQP+HVM FLLAE+GTSGSLDGQQRLV+KG FAPKNFE
Sbjct: 151 LREGTKKTVFVNFMDLCKTMHRQPEHVMMFLLAEMGTSGSLDGQQRLVIKGRFAPKNFEA 210
Query: 361 ILRRYVSK 384
ILRRY+++
Sbjct: 211 ILRRYINE 218
Score = 97 bits (240), Expect = 1e-019
Identities = 47/66 (71%), Positives = 54/66 (81%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F +N +++L EYVIC GCKSPDTILSKENRLFFLRCE+CGS RSVA IKAGFVA
Sbjct: 202 RFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFFLRCEQCGSSRSVAPIKAGFVA 261
Query: 601 RVGRTK 618
+VGR K
Sbjct: 262 QVGRRK 267
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 217 bits (552), Expect = 7e-056
Identities = 107/128 (83%), Positives = 114/128 (89%), Gaps = 3/128 (2%)
Frame = +1
Query: 1 EEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 180
+E+ EGI L+ YPWEGSDRDY Y+ELL RVF ILRENNP+LAGDRRRTVMRPPQV
Sbjct: 95 DEEGEGIVLETPS---YPWEGSDRDYTYEELLDRVFTILRENNPDLAGDRRRTVMRPPQV 151
Query: 181 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEG 360
LREGTKK VFVNFMDLCKTMHRQPDHVM FLLAELGTSGSLDGQQRLVVKG FAPKNFEG
Sbjct: 152 LREGTKKAVFVNFMDLCKTMHRQPDHVMAFLLAELGTSGSLDGQQRLVVKGRFAPKNFEG 211
Query: 361 ILRRYVSK 384
ILRRYV++
Sbjct: 212 ILRRYVNE 219
Score = 98 bits (243), Expect = 5e-020
Identities = 47/64 (73%), Positives = 53/64 (82%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F +N + +L EYVICLGC+SPDTILSKENRLFFLRCEKCGSGRSVA KAGF+A
Sbjct: 203 RFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFFLRCEKCGSGRSVAPNKAGFMA 262
Query: 601 RVGR 612
RVGR
Sbjct: 263 RVGR 266
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 161 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 220
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 221 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 271
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 167 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 226
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 227 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 277
Score = 64 bits (154), Expect = 9e-010
Identities = 32/64 (50%), Positives = 41/64 (64%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F + +++L EYV C C+SPDTIL K+ RL+FL+CE C S SVA IK GF A
Sbjct: 261 RFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQA 320
Query: 601 RVGR 612
GR
Sbjct: 321 VTGR 324
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 155 bits (390), Expect = 4e-037
Identities = 72/128 (56%), Positives = 94/128 (73%), Gaps = 1/128 (0%)
Frame = +1
Query: 4 EDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRR-RTVMRPPQV 180
+D + D + + W GSDRDY YDELL RVF I+ + NP++A R+ + VMRPPQV
Sbjct: 129 DDDKSEDKENDEDNSSTWFGSDRDYTYDELLKRVFEIILDKNPDMAAGRKPKFVMRPPQV 188
Query: 181 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEG 360
LR GTKKT F NFMD+ KT+HR P H+++FLLAELGTSGS+DG Q+L++KG F PK E
Sbjct: 189 LRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIEN 248
Query: 361 ILRRYVSK 384
+LRRY+ +
Sbjct: 249 VLRRYIKE 256
Score = 66 bits (160), Expect = 2e-010
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F + +++L EYV C C+SP+TIL K+ RLFFL+CE CGS SVA IK+GF A
Sbjct: 240 RFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTRLFFLQCESCGSRCSVASIKSGFQA 299
Query: 601 RVGR 612
G+
Sbjct: 300 VTGK 303
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 167 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 226
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 227 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 277
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 165 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 224
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 225 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 275
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 167 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 226
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 227 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 277
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 155 bits (390), Expect = 4e-037
Identities = 70/111 (63%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Frame = +1
Query: 55 WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLC 231
W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+C
Sbjct: 167 WAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDIC 226
Query: 232 KTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK 384
K +HRQP H++ FLLAELGTSGS+DG +LV+KG F K E +LRRY+ +
Sbjct: 227 KLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKE 277
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 137 bits (343), Expect = 1e-031
Identities = 61/124 (49%), Positives = 93/124 (75%), Gaps = 1/124 (0%)
Frame = +1
Query: 40 QQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNF 219
Q PW G+DRDY Y EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF
Sbjct: 151 QGTIPWAGTDRDYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANF 209
Query: 220 MDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK*LSLW 399
++C T++R+ +HV N++ AELGT+GS+DG QRLV++G F E ++R Y+S+ ++
Sbjct: 210 AEICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACR 269
Query: 400 SQKS 411
+ KS
Sbjct: 270 NCKS 273
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 134 bits (337), Expect = 6e-031
Identities = 64/110 (58%), Positives = 78/110 (70%), Gaps = 1/110 (0%)
Frame = +1
Query: 49 YPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDL 228
+ W SDRDY Y ELL R F +LR NNPELAG++R+ + PP V REG KKT+F N D+
Sbjct: 159 HAWLKSDRDYYYPELLNRFFTLLRTNNPELAGEKRKYTIVPPSVHREG-KKTIFANISDI 217
Query: 229 CKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYV 378
K MHR DHV+ FL AELGTSGS+DG RL++KG F K E +LRRY+
Sbjct: 218 SKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQQKQIENVLRRYI 267
Score = 74 bits (180), Expect = 9e-013
Identities = 34/66 (51%), Positives = 46/66 (69%)
Frame = +1
Query: 421 QFGVRNGDSLLLLLAAEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVA 600
+F + +++L EYV C CKSPDTIL+KENR+FF+ CE CGS RSV IK G+ A
Sbjct: 253 RFQQKQIENVLRRYIVEYVTCKTCKSPDTILTKENRIFFMTCEACGSVRSVQAIKTGYQA 312
Query: 601 RVGRTK 618
++G+ K
Sbjct: 313 QIGKRK 318
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 121 bits (302), Expect = 7e-027
Identities = 66/147 (44%), Positives = 91/147 (61%), Gaps = 9/147 (6%)
Frame = +1
Query: 82 YDELLGRVFNILRENNPELAGDRRRTVMR--PPQVLREGTKKTVFVNFMDLCKTMHRQPD 255
Y ELL R FNILR NNPELAGDR R PP LR+G KKT+F N D+ + +HR P+
Sbjct: 131 YSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPE 189
Query: 256 HVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEGILRRYVSK*LSLWSQKSK*YQFGVR 435
H++ +L AELGTSGS+DGQ+RLV+KG F K E +LRRY+ + ++ + KS +
Sbjct: 190 HLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKRE 249
Query: 436 NGDSLLLLLAAEYVICLGCKSPDTILS 516
+ L +++C C S ++ S
Sbjct: 250 QSNRLF------FMVCKSCGSTRSVSS 270
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 119 bits (296), Expect = 3e-026
Identities = 53/128 (41%), Positives = 85/128 (66%)
Frame = +1
Query: 1 EEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 180
EE +++ Q +G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V
Sbjct: 62 EEKVPTLEIGIGAQNLIDAKGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEV 121
Query: 181 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGGFAPKNFEG 360
R G+KKT F NF+++C+ M RQ HV+ FLLAELGT+GS+DG L+VKG + K FE
Sbjct: 122 ARAGSKKTAFSNFLEICRLMKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFES 181
Query: 361 ILRRYVSK 384
+LR+Y+ +
Sbjct: 182 VLRKYIKE 189
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 224,586,243,839
Number of Sequences: 518415
Number of Extensions: 224586243839
Number of Successful Extensions: 1413644693
Number of sequences better than 0.0: 0
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