BLASTX 7.6.2
Query= UN66731 /QuerySize=708
(707 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondr... 361 3e-099
sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondr... 353 7e-097
sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochon... 350 8e-096
sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondria... 349 2e-095
sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochon... 338 3e-092
sp|O13972|GLYD_SCHPO Probable serine hydroxymethyltransferase, c... 240 7e-063
sp|Q10104|GLYC_SCHPO Probable serine hydroxymethyltransferase, c... 239 1e-062
sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dicty... 235 2e-061
sp|O13425|GLYM_CANAL Serine hydroxymethyltransferase, mitochondr... 235 4e-061
sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic ... 233 1e-060
sp|O13426|GLYC_CANAL Serine hydroxymethyltransferase, cytosolic ... 231 5e-060
sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic ... 231 5e-060
sp|Q60V73|GLYC_CAEBR Serine hydroxymethyltransferase OS=Caenorha... 230 1e-059
sp|P50432|GLYC_CAEEL Serine hydroxymethyltransferase OS=Caenorha... 229 2e-059
sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic ... 228 3e-059
sp|Q75BQ6|GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic ... 228 3e-059
sp|Q6FUP6|GLYC_CANGA Serine hydroxymethyltransferase, cytosolic ... 226 1e-058
sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic ... 226 1e-058
sp|P35623|GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic ... 226 1e-058
sp|Q7S5N8|GLYM_NEUCR Putative serine hydroxymethyltransferase, m... 225 2e-058
>sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondrial
OS=Arabidopsis thaliana GN=SHM1 PE=1 SV=1
Length = 517
Score = 361 bits (925), Expect = 3e-099
Identities = 181/214 (84%), Positives = 190/214 (88%), Gaps = 4/214 (1%)
Frame = +2
Query: 77 MALALRRLSSSLKKP----IFSNGRFMSSLSTSTMAESERSRSSWVKQLNAPLEEVDPEI 244
MA+ALRRLSSS+ KP I S +MSSL + + E ERSR +W KQLNAPLEEVDPEI
Sbjct: 3 MAMALRRLSSSIDKPIRPLIRSTSCYMSSLPSEAVDEKERSRVTWPKQLNAPLEEVDPEI 62
Query: 245 ADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMAE 424
ADIIE EKARQWKG ELIPSENFTS SVM+AVGSVMTNKYSEGYPGARYYGGNEYIDMAE
Sbjct: 63 ADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAE 122
Query: 425 SLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHGY 604
+LCQKRALEAF LDP KWGVNVQ LSGSPANF VYTALLKPHERIMA DLPHGGHLSHGY
Sbjct: 123 TLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLPHGGHLSHGY 182
Query: 605 QTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
QTDTKKISAVSIFFETMPYRLDESTGYIDYDQ+E
Sbjct: 183 QTDTKKISAVSIFFETMPYRLDESTGYIDYDQME 216
>sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondrial OS=Solanum
tuberosum PE=2 SV=1
Length = 518
Score = 353 bits (905), Expect = 7e-097
Identities = 178/215 (82%), Positives = 191/215 (88%), Gaps = 5/215 (2%)
Frame = +2
Query: 77 MALALRRLSSSLKKPIFS--NG---RFMSSLSTSTMAESERSRSSWVKQLNAPLEEVDPE 241
MA+ALRRLS+++ KP+ S NG +MSSL + + E+S +W KQLNAPLE VDPE
Sbjct: 3 MAIALRRLSATVDKPVKSLYNGGSLYYMSSLPNEAVYDKEKSGVAWPKQLNAPLEVVDPE 62
Query: 242 IADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMA 421
IADIIE EKARQWKG ELIPSENFTS SVM+AVGSVMTNKYSEGYPGARYYGGNEYIDMA
Sbjct: 63 IADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMA 122
Query: 422 ESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHG 601
E+LCQKRALEAF LDP+KWGVNVQ LSGSPANFQVYTALLKPHERIMA DLPHGGHLSHG
Sbjct: 123 ETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALDLPHGGHLSHG 182
Query: 602 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE
Sbjct: 183 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 217
>sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 350 bits (896), Expect = 8e-096
Identities = 178/215 (82%), Positives = 188/215 (87%), Gaps = 5/215 (2%)
Frame = +2
Query: 77 MALALRRLSSSLKKP---IFSNGRF--MSSLSTSTMAESERSRSSWVKQLNAPLEEVDPE 241
MALALRRLSSS KP +F+ G MSSL + + E ER +W KQLNAPLE VDPE
Sbjct: 3 MALALRRLSSSADKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVVDPE 62
Query: 242 IADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMA 421
IADIIELEKARQWKG ELIPSENFTS SVM+AVGSVMTNKYSEGYPGARYYGGNEYIDMA
Sbjct: 63 IADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMA 122
Query: 422 ESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHG 601
E+LCQKRALEAF LDP+KWGVNVQ LSGSPANF VYTALLK H+RIMA DLPHGGHLSHG
Sbjct: 123 ETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLSHG 182
Query: 602 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
YQTDTKKISAVSIFFETMPYRL+ESTGYIDYDQLE
Sbjct: 183 YQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLE 217
>sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondrial OS=Pisum
sativum PE=1 SV=1
Length = 518
Score = 349 bits (893), Expect = 2e-095
Identities = 174/215 (80%), Positives = 189/215 (87%), Gaps = 5/215 (2%)
Frame = +2
Query: 77 MALALRRLSSSLKK---PIFSNGR--FMSSLSTSTMAESERSRSSWVKQLNAPLEEVDPE 241
MA+ALR+LSSS+ K P+FS + SSL + + E R +W KQLN+PLE +DPE
Sbjct: 3 MAMALRKLSSSVNKSSRPLFSASSLYYKSSLPDEAVYDKENPRVTWPKQLNSPLEVIDPE 62
Query: 242 IADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMA 421
IADIIELEKARQWKG ELIPSENFTS SVM+AVGSVMTNKYSEGYPGARYYGGNEYIDMA
Sbjct: 63 IADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMA 122
Query: 422 ESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHG 601
E+LCQKRALEAF LDP+KWGVNVQ LSGSP+NFQVYTALLKPH+RIMA DLPHGGHLSHG
Sbjct: 123 ETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALDLPHGGHLSHG 182
Query: 602 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE
Sbjct: 183 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 217
>sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 338 bits (865), Expect = 3e-092
Identities = 174/215 (80%), Positives = 184/215 (85%), Gaps = 5/215 (2%)
Frame = +2
Query: 77 MALALRRLSSSLKKP---IFSNGRF--MSSLSTSTMAESERSRSSWVKQLNAPLEEVDPE 241
MA ALRRLSSS KP +F+ G MSSL + + E ER +W KQLNAPLE DPE
Sbjct: 3 MASALRRLSSSSNKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVGDPE 62
Query: 242 IADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMA 421
IADIIELEKARQWKG ELI SENFTS SVM+AVGSVMTNKYSEGYPGARYYGGNEYIDMA
Sbjct: 63 IADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMA 122
Query: 422 ESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHG 601
E+LCQKRALEAF LD +KWGVNVQ LSGSPANF VYTALLK H+RIMA DLPHGGHLSHG
Sbjct: 123 ETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLSHG 182
Query: 602 YQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
YQTDTKKISAVSIFFETMPYRL+ESTGYIDYDQLE
Sbjct: 183 YQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLE 217
>sp|O13972|GLYD_SCHPO Probable serine hydroxymethyltransferase, cytosolic
OS=Schizosaccharomyces pombe GN=SPAC24C9.12c PE=2 SV=1
Length = 467
Score = 240 bits (612), Expect = 7e-063
Identities = 114/163 (69%), Positives = 135/163 (82%)
Frame = +2
Query: 218 PLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYG 397
PL+E DP +A+I+ E RQ LI SENFTS +VM+A+GSVM+NKYSEGYPGARYYG
Sbjct: 11 PLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEGYPGARYYG 70
Query: 398 GNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLP 577
GN++ID E+LCQ+RAL AF+LDP+KWGVNVQ LSGSPAN QVY A++ PH R+M DLP
Sbjct: 71 GNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLP 130
Query: 578 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
GGHLSHGYQTDTKKISAVS +FE+MPYR+D +TG IDYD LE
Sbjct: 131 SGGHLSHGYQTDTKKISAVSTYFESMPYRVDPNTGLIDYDMLE 173
>sp|Q10104|GLYC_SCHPO Probable serine hydroxymethyltransferase, cytosolic
OS=Schizosaccharomyces pombe GN=shm2 PE=2 SV=1
Length = 472
Score = 239 bits (609), Expect = 1e-062
Identities = 113/169 (66%), Positives = 132/169 (78%)
Frame = +2
Query: 200 VKQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYP 379
+K L APL E DP + I+E EK+RQ + LI SENFTS +VM+A+GS+M NKYSEGYP
Sbjct: 11 IKLLKAPLAECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYP 70
Query: 380 GARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERI 559
GARYYGGNE+ID AE LCQ RALEAFHLD KWGVNVQ SGSPAN Q Y A++KPH+R+
Sbjct: 71 GARYYGGNEFIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRL 130
Query: 560 MAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
M DLPHGGHLSHG+ T K ISAVS +F TMPY +++ TG IDYD LE
Sbjct: 131 MGLDLPHGGHLSHGFSTPQKAISAVSTYFSTMPYNVNKETGIIDYDSLE 179
>sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dictyostelium
discoideum GN=shmt1 PE=1 SV=1
Length = 457
Score = 235 bits (599), Expect = 2e-061
Identities = 115/165 (69%), Positives = 135/165 (81%), Gaps = 1/165 (0%)
Frame = +2
Query: 212 NAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARY 391
N PL+EVD EI +++ EK RQ+KG ELI SENFTS +VMEA+GS TNKY+EGYPG+RY
Sbjct: 7 NTPLKEVDNEIFELMNREKDRQFKGLELIASENFTSRAVMEALGSHFTNKYAEGYPGSRY 66
Query: 392 YGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPD 571
YGG E +D E+LCQKRAL+AF LD SKWGVNVQ SGSPANF VYTALL+PH+RIM D
Sbjct: 67 YGGTEVVDELETLCQKRALKAFRLDESKWGVNVQPYSGSPANFAVYTALLRPHDRIMGLD 126
Query: 572 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
LP GGHL+HGYQTD KKISA SIFFE+MPY++ + G IDY +LE
Sbjct: 127 LPSGGHLTHGYQTDKKKISASSIFFESMPYQIG-ADGLIDYQRLE 170
>sp|O13425|GLYM_CANAL Serine hydroxymethyltransferase, mitochondrial OS=Candida
albicans GN=SHM1 PE=3 SV=1
Length = 493
Score = 235 bits (597), Expect = 4e-061
Identities = 115/200 (57%), Positives = 149/200 (74%), Gaps = 4/200 (2%)
Frame = +2
Query: 107 SLKKPIFSNGRFMSSLSTSTMAESERSRSSWVKQLNAPLEEVDPEIADIIELEKARQWKG 286
+L++ + + + + + + T A S +++ ++ +++VDPE+ADI+ E+ RQ
Sbjct: 5 TLRRSVRAQSKNLPAFARRTYAVSPSAQA----LISKSVQDVDPEMADILNQERTRQKNS 60
Query: 287 FELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMAESLCQKRALEAFHLD 466
LIPSENFTS +VM+ +GS M NKYSEGYPG RYYGGNE ID AE+LCQKRALEAF LD
Sbjct: 61 ITLIPSENFTSKAVMDLLGSEMQNKYSEGYPGERYYGGNEIIDKAEALCQKRALEAFGLD 120
Query: 467 PSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHGYQTDTKKISAVSIFF 646
PS+WGVNVQ LSG+PAN Y+A+L+ +RIM DLPHGGHLSHGYQT T KIS +S +F
Sbjct: 121 PSQWGVNVQPLSGAPANLYAYSAILEVGDRIMGLDLPHGGHLSHGYQTKTTKISYISKYF 180
Query: 647 ETMPYRLDESTGYIDYDQLE 706
+TMPYRL+E TG IDYD LE
Sbjct: 181 QTMPYRLNEETGIIDYDTLE 200
>sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic OS=Mus musculus
GN=Shmt1 PE=1 SV=2
Length = 478
Score = 233 bits (592), Expect = 1e-060
Identities = 113/180 (62%), Positives = 136/180 (75%), Gaps = 3/180 (1%)
Frame = +2
Query: 176 SERSRSSWV---KQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGS 346
++R + W K L+ PL++ D E+ II+ E RQ G ELI SENF S +V+EA+GS
Sbjct: 2 ADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGS 61
Query: 347 VMTNKYSEGYPGARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQV 526
+ NKYSEGYPG RYYGG E+ID E LCQKRAL+A+HLDP WGVNVQ SGSPANF V
Sbjct: 62 SLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAV 121
Query: 527 YTALLKPHERIMAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
YTAL++PH RIM DLP GGHL+HG+ TD KKISA SIFFE+MPY++ TGYI+YDQLE
Sbjct: 122 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLE 181
>sp|O13426|GLYC_CANAL Serine hydroxymethyltransferase, cytosolic OS=Candida
albicans GN=SHM2 PE=1 SV=3
Length = 470
Score = 231 bits (587), Expect = 5e-060
Identities = 110/162 (67%), Positives = 130/162 (80%)
Frame = +2
Query: 221 LEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGG 400
L++ DPE+ II+ E RQ LI SENFT+ +V +A+G+ M NKYSEGYPGARYYGG
Sbjct: 18 LKDTDPEVDQIIKDEIDRQQHSIVLIASENFTTTAVFDALGTPMCNKYSEGYPGARYYGG 77
Query: 401 NEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPH 580
NE+I E LCQ+RAL+AF L P KWGVNVQ+LSGSPAN QVY A++KPHER+M DLPH
Sbjct: 78 NEHIHRMELLCQERALKAFGLTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPH 137
Query: 581 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
GGHLSHGYQTD++KISAVS +FETMPYR+D TG IDYD LE
Sbjct: 138 GGHLSHGYQTDSRKISAVSTYFETMPYRVDLETGLIDYDMLE 179
>sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens
GN=SHMT1 PE=1 SV=1
Length = 483
Score = 231 bits (587), Expect = 5e-060
Identities = 112/172 (65%), Positives = 134/172 (77%)
Frame = +2
Query: 191 SSWVKQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSE 370
SS K L PL++ D E+ +II+ E RQ G ELI SENF S +V+EA+GS + NKYSE
Sbjct: 16 SSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSE 75
Query: 371 GYPGARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPH 550
GYPG RYYGG E+ID E+LCQKRAL+A+ LDP WGVNVQ SGSPANF VYTAL++PH
Sbjct: 76 GYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPH 135
Query: 551 ERIMAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
RIM DLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TGYI+YDQLE
Sbjct: 136 GRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187
>sp|Q60V73|GLYC_CAEBR Serine hydroxymethyltransferase OS=Caenorhabditis briggsae
GN=mel-32 PE=3 SV=3
Length = 511
Score = 230 bits (584), Expect = 1e-059
Identities = 108/162 (66%), Positives = 134/162 (82%)
Frame = +2
Query: 221 LEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGG 400
+E++DPE+ +I++ EK+RQ +G ELI SENFTS +VM+A+GS M NKYSEGYPGARYYGG
Sbjct: 56 VEKIDPEVFNIMKNEKSRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 115
Query: 401 NEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPH 580
NE+ID E LCQKRALE F LDP+KWGVNVQSLSGSPANF VYTAL+ + RIM DLP
Sbjct: 116 NEFIDQMEILCQKRALEVFGLDPAKWGVNVQSLSGSPANFAVYTALVGANGRIMGLDLPD 175
Query: 581 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
GGHL+HG+ T +K+SA S FF++MPY++D +G IDYD+LE
Sbjct: 176 GGHLTHGFFTPARKVSATSEFFQSMPYKVDAQSGLIDYDKLE 217
>sp|P50432|GLYC_CAEEL Serine hydroxymethyltransferase OS=Caenorhabditis elegans
GN=mel-32 PE=1 SV=2
Length = 507
Score = 229 bits (583), Expect = 2e-059
Identities = 108/162 (66%), Positives = 133/162 (82%)
Frame = +2
Query: 221 LEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGG 400
+E+VDPE+ DI++ EK RQ +G ELI SENFTS +VM+A+GS M NKYSEGYPGARYYGG
Sbjct: 52 VEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 111
Query: 401 NEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPH 580
NE+ID E LCQKRALE F LDP+KWGVNVQ LSGSPANF VYTA++ + RIM DLP
Sbjct: 112 NEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPD 171
Query: 581 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
GGHL+HG+ T +K+SA S FF+++PY++D +TG IDYD+LE
Sbjct: 172 GGHLTHGFFTPARKVSATSEFFQSLPYKVDPTTGLIDYDKLE 213
>sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic OS=Oryctolagus
cuniculus GN=SHMT1 PE=1 SV=2
Length = 484
Score = 228 bits (581), Expect = 3e-059
Identities = 111/172 (64%), Positives = 133/172 (77%)
Frame = +2
Query: 191 SSWVKQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSE 370
SS + L PL++ D E+ DII+ E RQ G ELI SENF S +V+EA+GS + NKYSE
Sbjct: 16 SSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSE 75
Query: 371 GYPGARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPH 550
GYPG RYYGG E+ID E+LCQKRAL+A+ LDP WGVNVQ SGSPANF VYTAL++PH
Sbjct: 76 GYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPH 135
Query: 551 ERIMAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
RIM DLP GGHL+HG+ TD KKISA SIFFE+M Y+++ TGYIDYD+LE
Sbjct: 136 GRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLE 187
>sp|Q75BQ6|GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic OS=Ashbya
gossypii GN=SHM2 PE=3 SV=1
Length = 469
Score = 228 bits (580), Expect = 3e-059
Identities = 110/168 (65%), Positives = 131/168 (77%)
Frame = +2
Query: 203 KQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPG 382
K +++ L E DPE+ II+ E RQ LI SEN TS +V +A+G+ M NKYSEGYPG
Sbjct: 11 KLISSHLSESDPEVDAIIKDEIDRQKHSIVLIASENLTSTAVFDALGTPMCNKYSEGYPG 70
Query: 383 ARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIM 562
ARYYGGN++ID E LCQ+RALEAFH+ P +WGVNVQSLSGSPAN QVY AL+KPHER+M
Sbjct: 71 ARYYGGNQHIDRMELLCQRRALEAFHVTPDRWGVNVQSLSGSPANLQVYQALMKPHERLM 130
Query: 563 APDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
LP GGHLSHGYQT+T+KISAVS +FE+ PYR+D TG IDYD LE
Sbjct: 131 GLHLPDGGHLSHGYQTETRKISAVSTYFESFPYRVDPETGIIDYDTLE 178
>sp|Q6FUP6|GLYC_CANGA Serine hydroxymethyltransferase, cytosolic OS=Candida
glabrata GN=SHM2 PE=3 SV=1
Length = 469
Score = 226 bits (576), Expect = 1e-058
Identities = 107/169 (63%), Positives = 131/169 (77%)
Frame = +2
Query: 200 VKQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYP 379
+K ++ L E DPE+ II+ E RQ +LI SENFT+ SV +A+G+ + NKYSEGYP
Sbjct: 10 LKMVSGHLSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYP 69
Query: 380 GARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERI 559
GARYYGGNE+ID E LCQ+RALEAFH+ P +WGVNVQ+LSGSPAN QVY AL+KPHER+
Sbjct: 70 GARYYGGNEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERL 129
Query: 560 MAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
M LP GGHLSHGY T+ +KISAVS +FE+ PYR++ TG IDYD LE
Sbjct: 130 MGLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLE 178
>sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic OS=Pongo abelii
GN=SHMT1 PE=2 SV=1
Length = 483
Score = 226 bits (576), Expect = 1e-058
Identities = 110/172 (63%), Positives = 132/172 (76%)
Frame = +2
Query: 191 SSWVKQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSE 370
SS K L PL++ D E+ +II+ E RQ G EL SENF S +V+EA+GS + NKYSE
Sbjct: 16 SSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELFASENFASQAVLEALGSCLNNKYSE 75
Query: 371 GYPGARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPH 550
GYPG RYYGG E+ID E+LCQKRAL+A+ LDP WGVNVQ SGSPANF VYTAL++PH
Sbjct: 76 GYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPH 135
Query: 551 ERIMAPDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
RIM DLP GGHL+HG+ T KKISA SIFFE+MPY+++ TGYI+YDQLE
Sbjct: 136 GRIMGLDLPDGGHLTHGFMTGKKKISATSIFFESMPYKVNPDTGYINYDQLE 187
>sp|P35623|GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic OS=Ovis aries
GN=SHMT1 PE=1 SV=3
Length = 484
Score = 226 bits (575), Expect = 1e-058
Identities = 109/168 (64%), Positives = 130/168 (77%)
Frame = +2
Query: 203 KQLNAPLEEVDPEIADIIELEKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPG 382
K L PL++ D E+ +II+ E RQ G ELI SENF S +V+EA+GS + NKYSEGYPG
Sbjct: 20 KMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 383 ARYYGGNEYIDMAESLCQKRALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIM 562
RYYGG E+ID E LCQKRAL+ + LDP WGVNVQ SGSPANF VYTAL++PH RIM
Sbjct: 80 QRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 563 APDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLE 706
DLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TGYI+YDQLE
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187
>sp|Q7S5N8|GLYM_NEUCR Putative serine hydroxymethyltransferase, mitochondrial
OS=Neurospora crassa GN=NCU05805 PE=3 SV=1
Length = 527
Score = 225 bits (573), Expect = 2e-058
Identities = 105/148 (70%), Positives = 124/148 (83%)
Frame = +2
Query: 263 EKARQWKGFELIPSENFTSASVMEAVGSVMTNKYSEGYPGARYYGGNEYIDMAESLCQKR 442
EK RQ + LIPSENFTS +V++A+GS M NKYSEGYPGARYYGGNE+ID +E LCQ R
Sbjct: 69 EKQRQKQFINLIPSENFTSQAVLDALGSPMQNKYSEGYPGARYYGGNEFIDASERLCQDR 128
Query: 443 ALEAFHLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMAPDLPHGGHLSHGYQTDTKK 622
ALE F LDP +WGVNVQ+LSG+PAN VY+AL+ H+R+M DLPHGGHLSHGYQT TKK
Sbjct: 129 ALETFGLDPKEWGVNVQALSGAPANLYVYSALMDTHDRLMGLDLPHGGHLSHGYQTPTKK 188
Query: 623 ISAVSIFFETMPYRLDESTGYIDYDQLE 706
IS +S +FET+PYRLDE TGYIDY++LE
Sbjct: 189 ISFISKYFETLPYRLDEKTGYIDYNKLE 216
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 227,473,488,116
Number of Sequences: 518415
Number of Extensions: 227473488116
Number of Successful Extensions: 1422309314
Number of sequences better than 0.0: 0
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