BLASTX 7.6.2
Query= UN68410 /QuerySize=486
(485 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabi... 166 7e-041
sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus ... 69 9e-012
sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo... 69 1e-011
sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xeno... 67 3e-011
sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=... 66 8e-011
sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase RNF12-B OS=Xen... 66 1e-010
sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase RNF12 OS=Xenop... 66 1e-010
sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=... 66 1e-010
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 65 1e-010
sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase RNF12-A OS=Xen... 65 1e-010
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 65 2e-010
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 65 2e-010
sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN... 64 3e-010
sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RLIM OS=Homo s... 64 3e-010
sp|Q9WTV7|RNF12_MOUSE E3 ubiquitin-protein ligase RLIM OS=Mus mu... 64 3e-010
sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN... 63 7e-010
sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens... 63 7e-010
sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 63 9e-010
sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf13... 63 9e-010
sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 P... 62 1e-009
>sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabidopsis thaliana
GN=SDIR1 PE=1 SV=1
Length = 273
Score = 166 bits (419), Expect = 7e-041
Identities = 77/91 (84%), Positives = 81/91 (89%)
Frame = -1
Query: 485 LTKQASTSSSAEKKQDSVSASKKGTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDP 306
L KQASTSSSAEK DS + SKKGTEDELTCSVCLEQVTVGE+VRTLPCLHQFHA CIDP
Sbjct: 181 LAKQASTSSSAEKMLDSANESKKGTEDELTCSVCLEQVTVGEIVRTLPCLHQFHAGCIDP 240
Query: 305 WLRQQGTCPVCKFKAHSGWQEQDDGTDDDDD 213
WLRQQGTCPVCKF+AHSGWQEQD+ DD D
Sbjct: 241 WLRQQGTCPVCKFRAHSGWQEQDEIDDDASD 271
>sp|Q3U2C5|RN149_MOUSE E3 ubiquitin-protein ligase RNF149 OS=Mus musculus
GN=Rnf149 PE=2 SV=2
Length = 394
Score = 69 bits (168), Expect = 9e-012
Identities = 32/72 (44%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Frame = -1
Query: 437 SVSASKKGTE-DELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK--- 270
+V +KG + D C+VC+E V +V+R LPC H FH +CIDPWL TCP+CK
Sbjct: 250 TVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDV 309
Query: 269 FKAHSGWQEQDD 234
KA W + +D
Sbjct: 310 IKALGYWGDPED 321
>sp|Q8NC42|RN149_HUMAN E3 ubiquitin-protein ligase RNF149 OS=Homo sapiens
GN=RNF149 PE=2 SV=2
Length = 400
Score = 69 bits (167), Expect = 1e-011
Identities = 32/72 (44%), Positives = 42/72 (58%), Gaps = 4/72 (5%)
Frame = -1
Query: 437 SVSASKKGTE-DELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK--- 270
+V +KG + D C+VC+E V +++R LPC H FH +CIDPWL TCP+CK
Sbjct: 254 TVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDV 313
Query: 269 FKAHSGWQEQDD 234
KA W E D
Sbjct: 314 IKALGYWGEPGD 325
>sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xenopus laevis
GN=rnf149 PE=2 SV=1
Length = 397
Score = 67 bits (163), Expect = 3e-011
Identities = 32/74 (43%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Frame = -1
Query: 434 VSASKKGTE-DELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK---F 267
V +KG + D C+VC+E ++VR LPC H FH +CIDPWL + TCP+CK
Sbjct: 250 VKKGEKGIDIDAENCAVCIENYKTKDLVRILPCKHIFHRLCIDPWLIEHRTCPMCKLDVI 309
Query: 266 KAHSGWQEQDDGTD 225
KA W E ++ D
Sbjct: 310 KALGFWVEPEETLD 323
>sp|Q68DV7|RNF43_HUMAN RING finger protein 43 OS=Homo sapiens GN=RNF43 PE=1
SV=1
Length = 783
Score = 66 bits (160), Expect = 8e-011
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Frame = -1
Query: 476 QASTSSSAEKKQDSVSASKKGTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLR 297
QAS + + DS S+ C++CLE+ + G+ +R + CLH+FH C+DPWL
Sbjct: 249 QASCRQARGEWPDSGSSCSSAP----VCAICLEEFSEGQELRVISCLHEFHRNCVDPWLH 304
Query: 296 QQGTCPVCKFKAHSG 252
Q TCP+C F G
Sbjct: 305 QHRTCPLCMFNITEG 319
>sp|Q7T037|RF12B_XENLA E3 ubiquitin-protein ligase RNF12-B OS=Xenopus laevis
GN=rnf12-b PE=2 SV=1
Length = 757
Score = 66 bits (159), Expect = 1e-010
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = -1
Query: 440 DSVSASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
D++S G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 687 DNLSTRNYGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 744
>sp|Q07G42|RNF12_XENTR E3 ubiquitin-protein ligase RNF12 OS=Xenopus tropicalis
GN=rnf12 PE=2 SV=1
Length = 639
Score = 66 bits (159), Expect = 1e-010
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = -1
Query: 440 DSVSASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
D++S G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 569 DNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 626
>sp|Q5NCP0|RNF43_MOUSE RING finger protein 43 OS=Mus musculus GN=Rnf43 PE=2
SV=1
Length = 784
Score = 66 bits (159), Expect = 1e-010
Identities = 23/48 (47%), Positives = 33/48 (68%)
Frame = -1
Query: 395 CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCKFKAHSG 252
C++CLE+ + G+ +R + CLH+FH C+DPWL Q TCP+C F G
Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHRTCPLCMFNIVEG 319
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 65 bits (158), Expect = 1e-010
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = -1
Query: 401 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCKFKAHSG 252
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 226 LECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 274
>sp|Q641J8|RF12A_XENLA E3 ubiquitin-protein ligase RNF12-A OS=Xenopus laevis
GN=rnf12-a PE=1 SV=1
Length = 622
Score = 65 bits (158), Expect = 1e-010
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = -1
Query: 440 DSVSASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
D++S G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 552 DNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICR 609
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 65 bits (157), Expect = 2e-010
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = -1
Query: 401 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCKFKAHSG 252
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 226 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 274
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 65 bits (157), Expect = 2e-010
Identities = 31/50 (62%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = -1
Query: 401 LTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCKFKAHSG 252
L C VC E TVGE VR LPC H FH CI PWL Q TCPVC+ K+ SG
Sbjct: 225 LECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCR-KSLSG 273
>sp|Q5SPX3|RN215_MOUSE RING finger protein 215 OS=Mus musculus GN=Rnf215 PE=2
SV=1
Length = 379
Score = 64 bits (155), Expect = 3e-010
Identities = 28/55 (50%), Positives = 36/55 (65%), Gaps = 3/55 (5%)
Frame = -1
Query: 431 SASKKGTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCKF 267
S + GTE TC+VCL+ + +R LPC H+FH C+DPWL Q TCP+CKF
Sbjct: 318 SLPEPGTE---TCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKF 369
>sp|Q9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RLIM OS=Homo sapiens GN=RLIM
PE=1 SV=3
Length = 624
Score = 64 bits (155), Expect = 3e-010
Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = -1
Query: 440 DSVSASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
D+++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 554 DNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 611
>sp|Q9WTV7|RNF12_MOUSE E3 ubiquitin-protein ligase RLIM OS=Mus musculus GN=Rlim
PE=1 SV=2
Length = 600
Score = 64 bits (155), Expect = 3e-010
Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Frame = -1
Query: 440 DSVSASKKGTEDEL-TCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
D+++ G D L TCSVC+ + T G +R LPC H++H CID WL + TCP+C+
Sbjct: 530 DNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 587
>sp|Q9Y6U7|RN215_HUMAN RING finger protein 215 OS=Homo sapiens GN=RNF215 PE=1
SV=2
Length = 377
Score = 63 bits (152), Expect = 7e-010
Identities = 28/67 (41%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Frame = -1
Query: 461 SSAEKKQDSVSASKKGTED--ELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQG 288
+S + ++ +S + +G D TC+VCL+ + +R LPC H+FH C+DPWL Q
Sbjct: 301 ASLKTRRCRLSRAAQGLPDPGAETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQ 360
Query: 287 TCPVCKF 267
TCP+CKF
Sbjct: 361 TCPLCKF 367
>sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens GN=ZNRF3 PE=2
SV=3
Length = 936
Score = 63 bits (152), Expect = 7e-010
Identities = 24/71 (33%), Positives = 40/71 (56%)
Frame = -1
Query: 482 TKQASTSSSAEKKQDSVSASKKGTEDELTCSVCLEQVTVGEVVRTLPCLHQFHAVCIDPW 303
T++ ++ S ++ + + C++CLE+ GE +R +PC H+FH C+DPW
Sbjct: 264 TRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPW 323
Query: 302 LRQQGTCPVCK 270
L Q TCP C+
Sbjct: 324 LLQHHTCPHCR 334
>sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1
Length = 419
Score = 63 bits (151), Expect = 9e-010
Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = -1
Query: 437 SVSASKKGTEDELT-CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
+V K T+ + C+VC+E +VVR LPC H FH C+DPWL + TCP+CK
Sbjct: 249 TVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCK 305
>sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf130 PE=1 SV=1
Length = 419
Score = 63 bits (151), Expect = 9e-010
Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = -1
Query: 437 SVSASKKGTEDELT-CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
+V K T+ + C+VC+E +VVR LPC H FH C+DPWL + TCP+CK
Sbjct: 249 TVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCK 305
>sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 PE=1 SV=1
Length = 419
Score = 62 bits (150), Expect = 1e-009
Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = -1
Query: 437 SVSASKKGTEDELT-CSVCLEQVTVGEVVRTLPCLHQFHAVCIDPWLRQQGTCPVCK 270
+V K T+ + C+VC+E +VVR LPC H FH C+DPWL + TCP+CK
Sbjct: 249 TVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCK 305
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 230,958,350,165
Number of Sequences: 518415
Number of Extensions: 230958350165
Number of Successful Extensions: 1437040323
Number of sequences better than 0.0: 0
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