BLASTX 7.6.2
Query= UN68434 /QuerySize=638
(637 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subun... 189 1e-047
sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subun... 189 2e-047
sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subun... 189 2e-047
sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subun... 186 2e-046
sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subun... 183 1e-045
sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5 OS=S... 155 2e-037
sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=S... 147 8e-035
>sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subunit 12 OS=Bos
taurus GN=PSMD12 PE=2 SV=3
Length = 456
Score = 189 bits (479), Expect = 1e-047
Identities = 92/183 (50%), Positives = 129/183 (70%)
Frame = +3
Query: 78 MGDSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 257
+ G L+ I+ LL+ EKQ R A ++ T + I+++C+EAK+W LLNE I+ LSK+
Sbjct: 34 LAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAIVKMCYEAKEWDLLNENIMLLSKR 93
Query: 258 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 437
R QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IK
Sbjct: 94 RSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIK 153
Query: 438 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
E G + EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K N +F
Sbjct: 154 EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKF 213
Query: 618 LMQ 626
+
Sbjct: 214 FQE 216
>sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subunit 12 OS=Homo
sapiens GN=PSMD12 PE=1 SV=3
Length = 456
Score = 189 bits (478), Expect = 2e-047
Identities = 91/183 (49%), Positives = 129/183 (70%)
Frame = +3
Query: 78 MGDSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 257
+ G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+
Sbjct: 34 LAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKR 93
Query: 258 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 437
R QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IK
Sbjct: 94 RSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIK 153
Query: 438 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
E G + EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K N +F
Sbjct: 154 EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKF 213
Query: 618 LMQ 626
+
Sbjct: 214 FQE 216
>sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo
abelii GN=PSMD12 PE=2 SV=3
Length = 456
Score = 189 bits (478), Expect = 2e-047
Identities = 91/183 (49%), Positives = 129/183 (70%)
Frame = +3
Query: 78 MGDSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 257
+ G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+
Sbjct: 34 LAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKR 93
Query: 258 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 437
R QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IK
Sbjct: 94 RSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIK 153
Query: 438 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
E G + EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K N +F
Sbjct: 154 EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKF 213
Query: 618 LMQ 626
+
Sbjct: 214 FQE 216
>sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 OS=Mus
musculus GN=Psmd12 PE=2 SV=3
Length = 456
Score = 186 bits (470), Expect = 2e-046
Identities = 90/180 (50%), Positives = 127/180 (70%)
Frame = +3
Query: 78 MGDSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 257
+ G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W L NE I+ LSK+
Sbjct: 34 LAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLHNENIMLLSKR 93
Query: 258 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 437
R QLKQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IK
Sbjct: 94 RSQLKQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIK 153
Query: 438 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
E G + EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+K N +F
Sbjct: 154 EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKF 213
>sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subunit 12
OS=Dictyostelium discoideum GN=psmD12 PE=2 SV=1
Length = 447
Score = 183 bits (463), Expect = 1e-045
Identities = 88/183 (48%), Positives = 135/183 (73%)
Frame = +3
Query: 78 MGDSGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 257
+ SG L +I+ LL EKQ R AE+ T K A EI++LC+EA L+NE+++ LSK+
Sbjct: 35 LAKSGKLIEAIENLLITEKQCRQAEDSPSTSKIAAEIIKLCYEAGRLDLVNEKLVLLSKR 94
Query: 258 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 437
RGQL+ A++++VQ++M Y+DQ D++ ++ELI TL +S GKI+VE ERARLT+ L+KIK
Sbjct: 95 RGQLRPAIKAIVQESMVYVDQITDMKQKLELIDTLRTISDGKIFVENERARLTKTLSKIK 154
Query: 438 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
ED+G IA AA ++Q++ VET+G M K EKI F ++Q+R+C++ +D++RAQ++ K N +
Sbjct: 155 EDEGDIASAAKILQDLQVETYGTMEKREKITFFIDQMRICMNNKDFIRAQLIGNKVNRKT 214
Query: 618 LMQ 626
L +
Sbjct: 215 LAE 217
>sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5
OS=Schizosaccharomyces pombe GN=rpn5a PE=1 SV=1
Length = 443
Score = 155 bits (391), Expect = 2e-037
Identities = 80/175 (45%), Positives = 121/175 (69%)
Frame = +3
Query: 93 NLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQLK 272
+++A++++LL EKQ+R A + + K I L F A D++ LNEQ+++L KK GQLK
Sbjct: 27 DIDANLEKLLIFEKQVRQASDTSTNTKVLIYIADLLFRAGDFQGLNEQLVSLFKKHGQLK 86
Query: 273 QAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQGQ 452
Q++ S+VQ M Y+ D++T+I LI+TL ++ GKIYVE+ERARLT+ L++IKE+QG
Sbjct: 87 QSMTSLVQHVMTYLPGIDDLKTKINLIETLRTITDGKIYVEVERARLTQLLSQIKEEQGD 146
Query: 453 IAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKTNLEF 617
I A +++ VET+G+ EK+AFIL+QVRL L R DY A ++K N++F
Sbjct: 147 IKSAQEILCNEPVETYGSFDLKEKVAFILDQVRLFLLRSDYYMASTYTKKINVKF 201
>sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=Saccharomyces
cerevisiae GN=RPN5 PE=1 SV=3
Length = 445
Score = 147 bits (369), Expect = 8e-035
Identities = 75/169 (44%), Positives = 121/169 (71%), Gaps = 2/169 (1%)
Frame = +3
Query: 102 ASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQLKQAV 281
+++D+LL EK+ R A ++A +++ +I+ L W LNEQ+ LSKK GQLK ++
Sbjct: 34 SALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSI 93
Query: 282 QSMVQQAMQYI--DQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQGQI 455
Q M+Q+ M+Y+ ++ D+ TRI +I+T+ V+ KI+VE+ERAR+T+ L +IK+++G+I
Sbjct: 94 QYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKI 153
Query: 456 AEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRK 602
EAAD++ E+ VET+G+M +EKI FILEQ+ L + + DY +A +LSRK
Sbjct: 154 DEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRK 202
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 230,958,350,165
Number of Sequences: 518415
Number of Extensions: 230958350165
Number of Successful Extensions: 1437040323
Number of sequences better than 0.0: 0
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