BLASTX 7.6.2
Query= UN68788 /QuerySize=708
(707 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q05763|DRTS2_ARATH Bifunctional dihydrofolate reductase-thymi... 265 3e-070
sp|Q05762|DRTS1_ARATH Bifunctional dihydrofolate reductase-thymi... 216 2e-055
sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymid... 186 2e-046
sp|P45350|DRTS_DAUCA Bifunctional dihydrofolate reductase-thymid... 183 2e-045
sp|O81395|DRTS_MAIZE Bifunctional dihydrofolate reductase-thymid... 181 4e-045
sp|Q2QRX6|DRTS_ORYSJ Putative bifunctional dihydrofolate reducta... 157 7e-038
sp|Q93341|DYR_CAEEL Putative dihydrofolate reductase OS=Caenorha... 103 1e-021
sp|P22906|DYR_CANAL Dihydrofolate reductase OS=Candida albicans ... 95 3e-019
sp|P07807|DYR_YEAST Dihydrofolate reductase OS=Saccharomyces cer... 95 3e-019
sp|P16184|DYR_PNECA Dihydrofolate reductase OS=Pneumocystis cari... 92 4e-018
sp|Q27783|DRTS_TRYBB Bifunctional dihydrofolate reductase-thymid... 91 5e-018
sp|P28019|DYR_AEDAL Dihydrofolate reductase OS=Aedes albopictus ... 89 2e-017
sp|Q920D2|DYR_RAT Dihydrofolate reductase OS=Rattus norvegicus G... 89 3e-017
sp|P00375|DYR_MOUSE Dihydrofolate reductase OS=Mus musculus GN=D... 88 6e-017
sp|P00377|DYR_PIG Dihydrofolate reductase OS=Sus scrofa GN=DHFR ... 87 9e-017
sp|Q27793|DRTS_TRYCR Bifunctional dihydrofolate reductase-thymid... 87 1e-016
sp|P16126|DRTS_LEIAM Bifunctional dihydrofolate reductase-thymid... 86 2e-016
sp|P04753|DYR_MESAU Dihydrofolate reductase OS=Mesocricetus aura... 86 2e-016
sp|P09503|DYR_SHV21 Viral dihydrofolate reductase OS=Saimiriine ... 85 4e-016
sp|P07382|DRTS_LEIMA Bifunctional dihydrofolate reductase-thymid... 84 8e-016
>sp|Q05763|DRTS2_ARATH Bifunctional dihydrofolate reductase-thymidylate synthase
2 OS=Arabidopsis thaliana GN=THY-2 PE=2 SV=2
Length = 565
Score = 265 bits (676), Expect = 3e-070
Identities = 132/168 (78%), Positives = 147/168 (87%), Gaps = 2/168 (1%)
Frame = +3
Query: 102 LSILKALLPLSQRWLCKLPPNPNPSSLPNILKVSLSTMSNTLNGHVTSPSEPQRAYQVVV 281
L+ ALLPLSQRW CK +P PSSL NI KVS+STM+NTLNG+V S+PQ YQVVV
Sbjct: 13 LAFKSALLPLSQRWFCKF--SPKPSSLTNIFKVSISTMANTLNGNVIMTSKPQSTYQVVV 70
Query: 282 AATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPAKYKPLSG 461
AAT +MGIGKDGKLPW LPTDLKFFK+LTL+TSDSAKKNAVVMGRKTWESIP KY+PLSG
Sbjct: 71 AATKEMGIGKDGKLPWNLPTDLKFFKDLTLSTSDSAKKNAVVMGRKTWESIPKKYRPLSG 130
Query: 462 RLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
RLNVVL+RSSGFD+AN ENVVTCSS++SALDLLA PP+ LSIEKVFVI
Sbjct: 131 RLNVVLSRSSGFDIANTENVVTCSSIDSALDLLAAPPFSLSIEKVFVI 178
>sp|Q05762|DRTS1_ARATH Bifunctional dihydrofolate reductase-thymidylate synthase
1 OS=Arabidopsis thaliana GN=THY-1 PE=2 SV=2
Length = 519
Score = 216 bits (548), Expect = 2e-055
Identities = 108/132 (81%), Positives = 118/132 (89%), Gaps = 2/132 (1%)
Frame = +3
Query: 216 SNTLNGHVTS--PSEPQRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSA 389
+ TLN VT+ SEPQR YQVVVAAT +MGIGKDGKLPW LPTDLKFFK++TLTTSDS+
Sbjct: 3 TTTLNDSVTTTLASEPQRTYQVVVAATKEMGIGKDGKLPWNLPTDLKFFKDITLTTSDSS 62
Query: 390 KKNAVVMGRKTWESIPAKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQP 569
KKNAVVMGRKTWESIP KY+PLSGRLNVVLTRS GFD+AN ENVVTCSSV+SALDLLA P
Sbjct: 63 KKNAVVMGRKTWESIPIKYRPLSGRLNVVLTRSGGFDIANTENVVTCSSVDSALDLLAAP 122
Query: 570 PYRLSIEKVFVI 605
PY LSIE+VFVI
Sbjct: 123 PYCLSIERVFVI 134
>sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Glycine max PE=1 SV=1
Length = 530
Score = 186 bits (470), Expect = 2e-046
Identities = 92/126 (73%), Positives = 101/126 (80%)
Frame = +3
Query: 228 NGHVTSPSEPQRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVV 407
NG V QR YQVVVAAT GIGKDGKLPW LPTDLKFFKE+T+ TS+ KKNA+V
Sbjct: 14 NGSVNPLPNLQRTYQVVVAATQDWGIGKDGKLPWRLPTDLKFFKEITMKTSEPGKKNAIV 73
Query: 408 MGRKTWESIPAKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSI 587
MGRKTWESIP +Y+PLSGRLNVVLTRS FD+A AENVV C S+ SAL+LLA PY LSI
Sbjct: 74 MGRKTWESIPLEYRPLSGRLNVVLTRSGSFDIATAENVVICGSMSSALELLAASPYSLSI 133
Query: 588 EKVFVI 605
EKVFVI
Sbjct: 134 EKVFVI 139
>sp|P45350|DRTS_DAUCA Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Daucus carota PE=2 SV=1
Length = 528
Score = 183 bits (462), Expect = 2e-045
Identities = 87/131 (66%), Positives = 106/131 (80%)
Frame = +3
Query: 213 MSNTLNGHVTSPSEPQRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAK 392
++N NG + +PQR YQVVVAAT MGIGKDGKLPW LP+D+KFFK++T+TTSD K
Sbjct: 6 LANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTTSDPLK 65
Query: 393 KNAVVMGRKTWESIPAKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPP 572
+NAV+MGRKTWESIP +++PL GRLNVVLTRS FD+A ENVV C S+ SAL+LLA P
Sbjct: 66 RNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALELLAGSP 125
Query: 573 YRLSIEKVFVI 605
Y +S+EKVFVI
Sbjct: 126 YCVSVEKVFVI 136
>sp|O81395|DRTS_MAIZE Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Zea mays GN=DRTS PE=2 SV=1
Length = 521
Score = 181 bits (459), Expect = 4e-045
Identities = 91/121 (75%), Positives = 96/121 (79%)
Frame = +3
Query: 243 SPSEPQRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKT 422
S PQR YQVVVA T MGIGKDG LPW LP DLKFFKELTLTTSD KKNAV+MGRKT
Sbjct: 10 SQGRPQRNYQVVVAGTRDMGIGKDGVLPWKLPGDLKFFKELTLTTSDPVKKNAVIMGRKT 69
Query: 423 WESIPAKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFV 602
WESIP K +PL GRLNV+LTRS FD A ENVV C S+ESAL+LLA PY LSIEKVFV
Sbjct: 70 WESIPVKSRPLPGRLNVILTRSGSFDFATVENVVICGSMESALELLASTPYCLSIEKVFV 129
Query: 603 I 605
I
Sbjct: 130 I 130
>sp|Q2QRX6|DRTS_ORYSJ Putative bifunctional dihydrofolate reductase-thymidylate
synthase OS=Oryza sativa subsp. japonica GN=Os12g0446900 PE=3 SV=2
Length = 494
Score = 157 bits (396), Expect = 7e-038
Identities = 74/103 (71%), Positives = 86/103 (83%)
Frame = +3
Query: 297 MGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPAKYKPLSGRLNVV 476
MGIGKDG LPW LP DLKFFK++T+TTSD +KKNAVVMGRKTWESIP K++PL GRLNV+
Sbjct: 1 MGIGKDGTLPWKLPGDLKFFKDITVTTSDPSKKNAVVMGRKTWESIPLKFRPLPGRLNVI 60
Query: 477 LTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
LTRS FD A AENVV C S++SAL LLA PY L++EK F+I
Sbjct: 61 LTRSGSFDFATAENVVICGSLDSALQLLATTPYCLTVEKTFII 103
>sp|Q93341|DYR_CAEEL Putative dihydrofolate reductase OS=Caenorhabditis elegans
GN=dhfr-1 PE=2 SV=1
Length = 189
Score = 103 bits (256), Expect = 1e-021
Identities = 49/115 (42%), Positives = 78/115 (67%), Gaps = 2/115 (1%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPA 440
R ++VA + GIGK+G LPW + D+++F +T SD +K+NAV+MGRK WESIP
Sbjct: 2 RKMNLIVAMDAEGGIGKNGVLPWRIKKDMQYFASVTKNVSDQSKRNAVLMGRKCWESIPV 61
Query: 441 KYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
+PL+GRLN+VL+R +++ + +S+E+A+ LL++PP+ SIE ++ I
Sbjct: 62 TRRPLAGRLNIVLSRQ--LPAQKSDDYIVVNSLEAAMKLLSEPPFVDSIETIWNI 114
>sp|P22906|DYR_CANAL Dihydrofolate reductase OS=Candida albicans GN=DFR1 PE=1
SV=4
Length = 192
Score = 95 bits (235), Expect = 3e-019
Identities = 43/97 (44%), Positives = 70/97 (72%), Gaps = 1/97 (1%)
Frame = +3
Query: 273 VVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPAKYKP 452
+V A +GIG GK+PW L ++++FK++T T+ +NAV+MGRKTWESIP K++P
Sbjct: 9 IVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRP 68
Query: 453 LSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLA 563
L RLN++L+RS + + +N++ SS+ES+L+L++
Sbjct: 69 LPDRLNIILSRSYENKIID-DNIIHASSIESSLNLVS 104
>sp|P07807|DYR_YEAST Dihydrofolate reductase OS=Saccharomyces cerevisiae GN=DFR1
PE=1 SV=2
Length = 211
Score = 95 bits (235), Expect = 3e-019
Identities = 45/113 (39%), Positives = 77/113 (68%), Gaps = 3/113 (2%)
Frame = +3
Query: 273 VVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPAKYKP 452
+V +MGIG G LPW LP+++K+F+++T T D KKNA++MGRKTWESIP K++P
Sbjct: 11 IVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRP 70
Query: 453 LSGRLNVVLTRSSGFDVAN--AENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
L R+NV+++RS D + ++V +S+ +A+ + + ++ +E+++VI
Sbjct: 71 LPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAI-MNLESNFKEHLERIYVI 122
>sp|P16184|DYR_PNECA Dihydrofolate reductase OS=Pneumocystis carinii PE=1 SV=1
Length = 206
Score = 92 bits (226), Expect = 4e-018
Identities = 49/122 (40%), Positives = 77/122 (63%), Gaps = 8/122 (6%)
Frame = +3
Query: 258 QRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELT--LTTSDSAKK-NAVVMGRKTWE 428
Q++ ++VA T GIG+ LPW L ++ +FK +T + T DS + N V+MGRKTWE
Sbjct: 4 QKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWE 63
Query: 429 SIPAKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQ---PPYRLSIEKVF 599
SIP +++PL GR+NVV+TR+ D+ N + + S++ AL+LL + + I ++F
Sbjct: 64 SIPLQFRPLKGRINVVITRNESLDLGN--GIHSAKSLDHALELLYRTYGSESSVQINRIF 121
Query: 600 VI 605
VI
Sbjct: 122 VI 123
>sp|Q27783|DRTS_TRYBB Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Trypanosoma brucei brucei PE=3 SV=1
Length = 527
Score = 91 bits (225), Expect = 5e-018
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 10/135 (7%)
Frame = +3
Query: 177 SLPNILKVSLSTMSNTLNGHVTSPSEPQRAYQVVVAATNQMGIGKDGKLPWTLPTDLKFF 356
SL IL+ + + L G ++ P P R + VVVA+ + GIG G +PW +P D+++F
Sbjct: 3 SLTRILRKKIPV--HELAGKISRP--PLRPFSVVVASDEKGGIGDGGTIPWEIPEDMQYF 58
Query: 357 KELTL------TTSDSAKKNAVVMGRKTWESIPAKYKPLSGRLNVVLTRSSGFDVANAEN 518
+ +T +K+NAVVMGRKTW+S+P K++PLS RLNVVL+RS+ + A
Sbjct: 59 RRVTTNLRGKNVKPSPSKRNAVVMGRKTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGI 118
Query: 519 VVTCSSVESALDLLA 563
E+A D++A
Sbjct: 119 PDPIKRAEAANDVVA 133
>sp|P28019|DYR_AEDAL Dihydrofolate reductase OS=Aedes albopictus GN=DHFR PE=3
SV=1
Length = 186
Score = 89 bits (220), Expect = 2e-017
Identities = 44/115 (38%), Positives = 69/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIPA 440
+ + ++VA GIG G LPW L +LK+F +T DS K+NA++MGRKT+ +P
Sbjct: 2 KKFSLIVAVCANGGIGIKGDLPWRLRQELKYFSRMTKKIQDSGKRNAIIMGRKTYFGVPE 61
Query: 441 KYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
+PL RLN++LTR + +E V+ C+S++ AL L + P IE V+++
Sbjct: 62 SKRPLPERLNIILTRDPSANAYPSE-VMVCTSMQEALKKLDEAPLVNEIENVWIV 115
>sp|Q920D2|DYR_RAT Dihydrofolate reductase OS=Rattus norvegicus GN=Dhfr PE=2
SV=3
Length = 187
Score = 89 bits (218), Expect = 3e-017
Identities = 47/116 (40%), Positives = 68/116 (58%), Gaps = 3/116 (2%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPW-TLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIP 437
R +VA + MGIGK+G LPW L + K+F+ +T T+S K+N V+MGRKTW SIP
Sbjct: 3 RPLNCIVAVSQNMGIGKNGDLPWPLLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIP 62
Query: 438 AKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
K +PL R+N+VL+R A S++ AL L+ QP ++ V+V+
Sbjct: 63 EKNRPLKDRINIVLSRELKEPPQGAH--FLAKSLDDALKLIEQPELASKVDMVWVV 116
>sp|P00375|DYR_MOUSE Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3
Length = 187
Score = 88 bits (216), Expect = 6e-017
Identities = 46/116 (39%), Positives = 68/116 (58%), Gaps = 3/116 (2%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPW-TLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIP 437
R +VA + MGIGK+G LPW L + K+F+ +T T+S K+N V+MGRKTW SIP
Sbjct: 3 RPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIP 62
Query: 438 AKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
K +PL R+N+VL+R A S++ AL L+ QP ++ V+++
Sbjct: 63 EKNRPLKDRINIVLSRELKEPPRGAH--FLAKSLDDALRLIEQPELASKVDMVWIV 116
>sp|P00377|DYR_PIG Dihydrofolate reductase OS=Sus scrofa GN=DHFR PE=1 SV=1
Length = 186
Score = 87 bits (214), Expect = 9e-017
Identities = 46/116 (39%), Positives = 68/116 (58%), Gaps = 3/116 (2%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPW-TLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIP 437
R +VA + MGIGK+G LPW L + K+F+ +T T+S K+N V+MGRKTW SIP
Sbjct: 2 RPLNCIVAVSQNMGIGKNGDLPWPPLRNEYKYFQRMTTTSSVEGKQNLVIMGRKTWFSIP 61
Query: 438 AKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
K +PL R+N+VL+R A S++ AL L QP + ++ V+++
Sbjct: 62 EKNRPLKDRINIVLSRELKEPPQGAH--FLAKSLDDALKLTEQPELKDKVDMVWIV 115
>sp|Q27793|DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Trypanosoma cruzi PE=1 SV=2
Length = 521
Score = 87 bits (213), Expect = 1e-016
Identities = 42/80 (52%), Positives = 54/80 (67%), Gaps = 6/80 (7%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTL------TTSDSAKKNAVVMGRKT 422
RA+ +VVA GIG +PW +P D+KFF++LT AK+NAVVMGRKT
Sbjct: 21 RAFSLVVAVDEHGGIGDGRSIPWNVPEDMKFFRDLTTKLRGKNVKPSPAKRNAVVMGRKT 80
Query: 423 WESIPAKYKPLSGRLNVVLT 482
W+SIP K++PL GRLNVVL+
Sbjct: 81 WDSIPPKFRPLPGRLNVVLS 100
>sp|P16126|DRTS_LEIAM Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Leishmania amazonensis PE=3 SV=1
Length = 520
Score = 86 bits (211), Expect = 2e-016
Identities = 41/79 (51%), Positives = 53/79 (67%), Gaps = 5/79 (6%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSD-----SAKKNAVVMGRKTW 425
RA+ +VVA Q GIG +PW +P D+ FFK+ T + K+NAVVMGRKTW
Sbjct: 25 RAFSIVVALDKQHGIGDGESIPWRVPEDMAFFKDQTTLLRNKKPPTDKKRNAVVMGRKTW 84
Query: 426 ESIPAKYKPLSGRLNVVLT 482
ES+P K++PL GRLNVVL+
Sbjct: 85 ESVPVKFRPLKGRLNVVLS 103
>sp|P04753|DYR_MESAU Dihydrofolate reductase OS=Mesocricetus auratus GN=DHFR
PE=2 SV=4
Length = 187
Score = 86 bits (211), Expect = 2e-016
Identities = 45/116 (38%), Positives = 67/116 (57%), Gaps = 3/116 (2%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPW-TLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIP 437
R +VA + MGIGK+G PW L + K+F+ +T T+S K+N V+MGRKTW SIP
Sbjct: 3 RPLNCIVAVSQNMGIGKNGDFPWPMLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIP 62
Query: 438 AKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
K +PL R+N+VL+R A S++ AL L+ QP ++ V+++
Sbjct: 63 EKNRPLKDRINIVLSRELKEPPQGAH--FLAKSLDDALKLIEQPELADKVDMVWIV 116
>sp|P09503|DYR_SHV21 Viral dihydrofolate reductase OS=Saimiriine herpesvirus 2
(strain 11) GN=DHFR PE=3 SV=1
Length = 187
Score = 85 bits (209), Expect = 4e-016
Identities = 48/116 (41%), Positives = 66/116 (56%), Gaps = 3/116 (2%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPW-TLPTDLKFFKELTLTTSDSAKKNAVVMGRKTWESIP 437
+A +VA MGIGK G LPW L D K F+ +T T+S K+N V+MG+KTW SIP
Sbjct: 3 QALNCIVAVAQNMGIGKQGNLPWPRLMNDFKHFQRMTTTSSVPDKQNLVIMGKKTWFSIP 62
Query: 438 AKYKPLSGRLNVVLTRSSGFDVANAENVVTCSSVESALDLLAQPPYRLSIEKVFVI 605
K +PL GR+NVVL++ A S++ AL L QP ++ V++I
Sbjct: 63 EKNRPLKGRINVVLSKELKELPHRAH--FLAKSLDDALKLTEQPELANKVDMVWII 116
>sp|P07382|DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase
OS=Leishmania major PE=1 SV=1
Length = 520
Score = 84 bits (206), Expect = 8e-016
Identities = 40/79 (50%), Positives = 52/79 (65%), Gaps = 5/79 (6%)
Frame = +3
Query: 261 RAYQVVVAATNQMGIGKDGKLPWTLPTDLKFFKELTLTTSD-----SAKKNAVVMGRKTW 425
RA+ +VVA Q GIG +PW +P D+ FFK T + K+NAVVMGRKTW
Sbjct: 25 RAFSIVVALDMQHGIGDGESIPWRVPEDMTFFKNQTTLLRNKKPPTEKKRNAVVMGRKTW 84
Query: 426 ESIPAKYKPLSGRLNVVLT 482
ES+P K++PL GRLN+VL+
Sbjct: 85 ESVPVKFRPLKGRLNIVLS 103
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 230,958,350,165
Number of Sequences: 518415
Number of Extensions: 230958350165
Number of Successful Extensions: 1437040323
Number of sequences better than 0.0: 0
|
