BLASTX 7.6.2
Query= UN69233 /QuerySize=770
(769 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mu... 70 2e-011
sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Ratt... 70 2e-011
sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Ho... 68 7e-011
sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Po... 68 7e-011
sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Ga... 67 9e-011
sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bo... 67 2e-010
sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Ga... 66 3e-010
sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mu... 61 8e-009
sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Ho... 60 1e-008
sp|Q9NXG6|P4HTM_HUMAN Transmembrane prolyl 4-hydroxylase OS=Homo... 52 5e-006
sp|Q8BG58|P4HTM_MOUSE Transmembrane prolyl 4-hydroxylase OS=Mus ... 52 5e-006
>sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 70 bits (169), Expect = 2e-011
Identities = 42/110 (38%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Frame = -2
Query: 762 DKIIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRM 595
D ++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+
Sbjct: 391 DPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRI 450
Query: 594 ATMLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
AT L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 451 ATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN-LFASGEGDYSTR 499
>sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 70 bits (169), Expect = 2e-011
Identities = 42/110 (38%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Frame = -2
Query: 762 DKIIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRM 595
D ++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+
Sbjct: 391 DPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRI 450
Query: 594 ATMLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
AT L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 451 ATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN-LFASGEGDYSTR 499
>sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens
GN=P4HA1 PE=1 SV=2
Length = 534
Score = 68 bits (164), Expect = 7e-011
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRMAT 589
++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 393 VVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIAT 452
Query: 588 MLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 453 WLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN-LFASGEGDYSTR 499
>sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii
GN=P4HA1 PE=2 SV=1
Length = 534
Score = 68 bits (164), Expect = 7e-011
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRMAT 589
++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 393 VVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIAT 452
Query: 588 MLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 453 WLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN-LFASGEGDYSTR 499
>sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gallus
GN=P4HA1 PE=1 SV=1
Length = 516
Score = 67 bits (163), Expect = 9e-011
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDY----FVDEFNTKNGGQRMAT 589
++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 375 VVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIAT 434
Query: 588 MLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 435 WLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN-LFPSGEGDYSTR 481
Score = 52 bits (122), Expect = 5e-006
Identities = 21/47 (44%), Positives = 30/47 (63%)
Frame = -2
Query: 474 GLSVKPRMGDALLFWSMRPDATLDPSSLHGGCPVIRGNKWSSTKWMH 334
G SV P+ G A+ ++++ P D S+ H CPV+ GNKW S KW+H
Sbjct: 454 GASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLH 500
>sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus
GN=P4HA1 PE=1 SV=1
Length = 534
Score = 67 bits (161), Expect = 2e-010
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRMAT 589
++ I RI D T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 393 VVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIAT 452
Query: 588 MLMYLSDVEEGGETVFPAANMNY-----SSVPWYNDLFECGKKGLSVK 460
L Y+SDV GG TVFP + ++V WYN LF G+ S +
Sbjct: 453 WLFYMSDVLAGGATVFPEVGASVWPKKGTAVFWYN-LFASGEGDYSTR 499
>sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus
GN=P4HA2 PE=2 SV=1
Length = 534
Score = 66 bits (159), Expect = 3e-010
Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 8/102 (7%)
Frame = -2
Query: 762 DKIIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYFVDEFNT--KNGGQRMAT 589
D ++ + +R+ T + E LQV +Y G +YEPH+D+ F++ K+ G R+AT
Sbjct: 393 DPVVAKVNQRMQQITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSTLKSEGNRLAT 452
Query: 588 MLMYLSDVEEGGETVFPAAN-----MNYSSVPWYNDLFECGK 478
L Y+SDVE GG TVFP ++V WYN LF G+
Sbjct: 453 FLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYN-LFRSGE 493
>sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus
GN=P4ha2 PE=2 SV=1
Length = 537
Score = 61 bits (146), Expect = 8e-009
Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 9/95 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRMAT 589
++ + +R+ T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 396 VVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVAT 455
Query: 588 MLMYLSDVEEGGETVFPAAN-----MNYSSVPWYN 499
L Y+SDVE GG TVFP ++V WYN
Sbjct: 456 FLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYN 490
>sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens
GN=P4HA2 PE=1 SV=1
Length = 535
Score = 60 bits (144), Expect = 1e-008
Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 9/95 (9%)
Frame = -2
Query: 756 IIKTIEKRIADYTFIPADHGEGLQVLHYEEGQKYEPHYDYF----VDEFNTKNGGQRMAT 589
++ + +R+ T + E LQV +Y G +YEPH+D+ D F G R+AT
Sbjct: 394 VVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVAT 453
Query: 588 MLMYLSDVEEGGETVFPAAN-----MNYSSVPWYN 499
L Y+SDVE GG TVFP ++V WYN
Sbjct: 454 FLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYN 488
>sp|Q9NXG6|P4HTM_HUMAN Transmembrane prolyl 4-hydroxylase OS=Homo sapiens
GN=P4HTM PE=1 SV=2
Length = 502
Score = 52 bits (122), Expect = 5e-006
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 5/57 (8%)
Frame = -2
Query: 486 CGKKGLSVKPRMGDALLFWSMRPD-----ATLDPSSLHGGCPVIRGNKWSSTKWMHV 331
C K L VKP+ G A+ +++ PD +D SLHGGC V RG KW + W++V
Sbjct: 404 CDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWINV 460
>sp|Q8BG58|P4HTM_MOUSE Transmembrane prolyl 4-hydroxylase OS=Mus musculus
GN=P4htm PE=2 SV=1
Length = 503
Score = 52 bits (122), Expect = 5e-006
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 5/57 (8%)
Frame = -2
Query: 486 CGKKGLSVKPRMGDALLFWSMRPD-----ATLDPSSLHGGCPVIRGNKWSSTKWMHV 331
C K L VKP+ G A+ +++ PD +D SLHGGC V RG KW + W++V
Sbjct: 405 CDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINV 461
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 231,464,017,541
Number of Sequences: 518415
Number of Extensions: 231464017541
Number of Successful Extensions: 1443091064
Number of sequences better than 0.0: 0
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