BLASTX 7.6.2
Query= UN70593 /QuerySize=707
(706 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VYY9|Y1727_DROME TBC1 domain family member CG11727 OS=Droso... 91 8e-018
sp|Q5ZJ17|RBG1L_CHICK Rab GTPase-activating protein 1-like OS=Ga... 89 2e-017
sp|Q5R372|RBG1L_HUMAN Rab GTPase-activating protein 1-like OS=Ho... 89 2e-017
sp|Q5RCW6|RBG1L_PONAB Rab GTPase-activating protein 1-like OS=Po... 89 2e-017
sp|Q9Y3P9|RBGP1_HUMAN Rab GTPase-activating protein 1 OS=Homo sa... 87 9e-017
sp|A2AWA9|RBGP1_MOUSE Rab GTPase-activating protein 1 OS=Mus mus... 87 9e-017
sp|Q5RAN1|RBGP1_PONAB Rab GTPase-activating protein 1 OS=Pongo a... 87 9e-017
sp|A6H6A9|RBG1L_MOUSE Rab GTPase-activating protein 1-like OS=Mu... 87 1e-016
sp|Q4KMP7|TB10B_HUMAN TBC1 domain family member 10B OS=Homo sapi... 85 5e-016
sp|Q8BHL3|TB10B_MOUSE TBC1 domain family member 10B OS=Mus muscu... 85 5e-016
sp|Q96CN4|EVI5L_HUMAN EVI5-like protein OS=Homo sapiens GN=EVI5L... 83 1e-015
sp|Q9BXI6|TB10A_HUMAN TBC1 domain family member 10A OS=Homo sapi... 80 1e-014
sp|P58802|TB10A_MOUSE TBC1 domain family member 10A OS=Mus muscu... 80 1e-014
sp|O60447|EVI5_HUMAN Ecotropic viral integration site 5 protein ... 79 2e-014
sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 OS=Homo sapien... 74 6e-013
sp|Q8C9V1|TB10C_MOUSE Carabin OS=Mus musculus GN=Tbc1d10c PE=2 SV=1 72 2e-012
sp|Q8BYJ6|TBCD4_MOUSE TBC1 domain family member 4 OS=Mus musculu... 71 5e-012
sp|P97366|EVI5_MOUSE Ecotropic viral integration site 5 protein ... 70 9e-012
sp|Q86TI0|TBCD1_HUMAN TBC1 domain family member 1 OS=Homo sapien... 70 1e-011
sp|Q60949|TBCD1_MOUSE TBC1 domain family member 1 OS=Mus musculu... 69 3e-011
>sp|Q9VYY9|Y1727_DROME TBC1 domain family member CG11727 OS=Drosophila
melanogaster GN=CG11727 PE=1 SV=3
Length = 807
Score = 91 bits (223), Expect = 8e-018
Identities = 47/95 (49%), Positives = 64/95 (67%), Gaps = 8/95 (8%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVY--ETSASELDIIRDISRTFPSHV 599
+R+GIP R +VWQ +SG+ D G +Q Y TSA E I RDI+RT+P
Sbjct: 113 VRRGIPHHFRAIVWQQLSGASD------GDKKQYAEYIKATSACEKVIRRDIARTYPEVE 166
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
FF+++ GPGQ +L+NV+KAYS++DR+VGY QG GF
Sbjct: 167 FFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSGF 201
>sp|Q5ZJ17|RBG1L_CHICK Rab GTPase-activating protein 1-like OS=Gallus gallus
GN=RABGAP1L PE=2 SV=1
Length = 816
Score = 89 bits (219), Expect = 2e-017
Identities = 43/95 (45%), Positives = 61/95 (64%), Gaps = 6/95 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYE--QLVVYETSASELDIIRDISRTFPSHV 599
+++G+P+ LR VWQL++G D N + + ++++ SA E I RDI RTFP+H
Sbjct: 536 VKRGVPEALRAEVWQLLAGCHD----NEAMLDKYRILITMDSAQENVITRDIHRTFPAHD 591
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+F+ G GQ SLY + KAYSVYD D+GY QG F
Sbjct: 592 YFKDTEGDGQESLYKICKAYSVYDEDIGYCQGQSF 626
>sp|Q5R372|RBG1L_HUMAN Rab GTPase-activating protein 1-like OS=Homo sapiens
GN=RABGAP1L PE=1 SV=1
Length = 815
Score = 89 bits (219), Expect = 2e-017
Identities = 43/93 (46%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
++ G+P+ LR VWQL++G D M ++++ + SA E I RDI RTFP+H +F
Sbjct: 535 VKSGVPEALRAEVWQLLAGCHDNQAMLDRY--RILITKDSAQESVITRDIHRTFPAHDYF 592
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+ G GQ SLY + KAYSVYD D+GY QG F
Sbjct: 593 KDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
>sp|Q5RCW6|RBG1L_PONAB Rab GTPase-activating protein 1-like OS=Pongo abelii
GN=RABGAP1L PE=2 SV=1
Length = 815
Score = 89 bits (219), Expect = 2e-017
Identities = 43/93 (46%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
++ G+P+ LR VWQL++G D M ++++ + SA E I RDI RTFP+H +F
Sbjct: 535 VKSGVPEALRAEVWQLLAGCHDNQAMLDRY--RILITKDSAQESVITRDIHRTFPAHDYF 592
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+ G GQ SLY + KAYSVYD D+GY QG F
Sbjct: 593 KDTGGDGQESLYKICKAYSVYDEDIGYCQGQSF 625
>sp|Q9Y3P9|RBGP1_HUMAN Rab GTPase-activating protein 1 OS=Homo sapiens
GN=RABGAP1 PE=1 SV=3
Length = 1069
Score = 87 bits (214), Expect = 9e-017
Identities = 44/95 (46%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELD--IIRDISRTFPSHV 599
+R G+P+ LRG VWQL++G + N + E+ + T S D I RDI+RTFP+H
Sbjct: 563 VRNGVPEALRGEVWQLLAGCHN----NDHLVEKYRILITKESPQDSAITRDINRTFPAHD 618
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+F+ G GQ SLY + KAYSVYD ++GY QG F
Sbjct: 619 YFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSF 653
>sp|A2AWA9|RBGP1_MOUSE Rab GTPase-activating protein 1 OS=Mus musculus
GN=Rabgap1 PE=2 SV=1
Length = 1064
Score = 87 bits (214), Expect = 9e-017
Identities = 44/95 (46%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELD--IIRDISRTFPSHV 599
+R G+P+ LRG VWQL++G + N + E+ + T S D I RDI+RTFP+H
Sbjct: 558 VRSGVPEALRGEVWQLLAGCHN----NDHLVEKYRILITKESPQDSAITRDINRTFPAHD 613
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+F+ G GQ SLY + KAYSVYD ++GY QG F
Sbjct: 614 YFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSF 648
>sp|Q5RAN1|RBGP1_PONAB Rab GTPase-activating protein 1 OS=Pongo abelii
GN=RABGAP1 PE=2 SV=1
Length = 1069
Score = 87 bits (214), Expect = 9e-017
Identities = 44/95 (46%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELD--IIRDISRTFPSHV 599
+R G+P+ LRG VWQL++G + N + E+ + T S D I RDI+RTFP+H
Sbjct: 563 VRNGVPEALRGEVWQLLAGCHN----NDHLVEKYRILITKESPQDSAITRDINRTFPAHD 618
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+F+ G GQ SLY + KAYSVYD ++GY QG F
Sbjct: 619 YFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSF 653
>sp|A6H6A9|RBG1L_MOUSE Rab GTPase-activating protein 1-like OS=Mus musculus
GN=Rabgap1l PE=1 SV=1
Length = 815
Score = 87 bits (213), Expect = 1e-016
Identities = 42/93 (45%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
++ G+P+ LR VWQL++G D M ++++ + SA E I RDI RTFP+H +F
Sbjct: 535 VKSGVPEALRAEVWQLLAGCHDNQEMLDKY--RILITKDSAQESVITRDIHRTFPAHDYF 592
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+ G GQ SLY + KAYSV+D D+GY QG F
Sbjct: 593 KDTGGDGQESLYKICKAYSVFDEDIGYCQGQSF 625
>sp|Q4KMP7|TB10B_HUMAN TBC1 domain family member 10B OS=Homo sapiens GN=TBC1D10B
PE=1 SV=3
Length = 808
Score = 85 bits (208), Expect = 5e-016
Identities = 43/91 (47%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 423 RIRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDII-RDISRTFPSHV 599
R RKGIP LR WQ +S S++LL NPG +E+L LD+I +D+ R FP H
Sbjct: 356 RCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHE 415
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQ 692
F R G GQ+ LY +LKAY++Y D GY Q
Sbjct: 416 MFAARGGHGQQDLYRILKAYTIYRPDEGYCQ 446
>sp|Q8BHL3|TB10B_MOUSE TBC1 domain family member 10B OS=Mus musculus GN=Tbc1d10b
PE=1 SV=2
Length = 798
Score = 85 bits (208), Expect = 5e-016
Identities = 43/91 (47%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 423 RIRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDII-RDISRTFPSHV 599
R RKGIP LR WQ +S S++LL NPG +E+L LD+I +D+ R FP H
Sbjct: 342 RCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAAGDPKWLDVIEKDLHRQFPFHE 401
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQ 692
F R G GQ+ LY +LKAY++Y D GY Q
Sbjct: 402 MFAARGGHGQQDLYRILKAYTIYRPDEGYCQ 432
>sp|Q96CN4|EVI5L_HUMAN EVI5-like protein OS=Homo sapiens GN=EVI5L PE=1 SV=1
Length = 794
Score = 83 bits (204), Expect = 1e-015
Identities = 43/93 (46%), Positives = 60/93 (64%), Gaps = 3/93 (3%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
IRKGIP R +VWQL+ + D+ + N Y +L+ + +L I RDI+RT+P H FF
Sbjct: 112 IRKGIPHHFRAIVWQLLCSATDMPVKNQ--YSELLKMSSPCEKL-IRRDIARTYPEHEFF 168
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+ + GQ L+NV+KAYS+ DR+VGY QG F
Sbjct: 169 KGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAF 201
>sp|Q9BXI6|TB10A_HUMAN TBC1 domain family member 10A OS=Homo sapiens GN=TBC1D10A
PE=1 SV=1
Length = 508
Score = 80 bits (195), Expect = 1e-014
Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 423 RIRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDII-RDISRTFPSHV 599
R +KGIP LRG WQ +SG + L NPG +++L + LD+I RD+ R FP H
Sbjct: 107 RCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHE 166
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQ 692
F R G GQ+ L+ VLKAY++Y + GY Q
Sbjct: 167 MFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQ 197
>sp|P58802|TB10A_MOUSE TBC1 domain family member 10A OS=Mus musculus GN=Tbc1d10a
PE=1 SV=1
Length = 500
Score = 80 bits (195), Expect = 1e-014
Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 423 RIRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDII-RDISRTFPSHV 599
R +KGIP LRG WQ +SG + L NPG +++L + LD+I RD+ R FP H
Sbjct: 107 RCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFPFHE 166
Query: 600 FFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQ 692
F R G GQ+ L+ VLKAY++Y + GY Q
Sbjct: 167 MFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQ 197
>sp|O60447|EVI5_HUMAN Ecotropic viral integration site 5 protein homolog OS=Homo
sapiens GN=EVI5 PE=1 SV=2
Length = 810
Score = 79 bits (194), Expect = 2e-014
Identities = 41/93 (44%), Positives = 60/93 (64%), Gaps = 3/93 (3%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
+ KGIP R +VWQL+ ++ + + + Y +L+ TS E I RDI+RT+P H FF
Sbjct: 160 VHKGIPHHFRAIVWQLLCSAQSMPIKDQ--YSELLKM-TSPCEKLIRRDIARTYPEHNFF 216
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
+++ GQ L+NV+KAYS+ DR+VGY QG F
Sbjct: 217 KEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAF 249
>sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4
PE=1 SV=2
Length = 1298
Score = 74 bits (181), Expect = 6e-013
Identities = 38/99 (38%), Positives = 63/99 (63%), Gaps = 6/99 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDL--LLMN----PGVYEQLVVYETSASELDIIRDISRTF 587
+++G+P RG +WQ ++ L L N P + + ++ + +A + I+ D+ RTF
Sbjct: 915 LKEGVPKSRRGEIWQFLALQYRLRHRLPNKQQPPDISYKELLKQLTAQQHAILVDLGRTF 974
Query: 588 PSHVFFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
P+H +F + GPGQ SL+N+LKAYS+ D++VGY QG+ F
Sbjct: 975 PTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISF 1013
>sp|Q8C9V1|TB10C_MOUSE Carabin OS=Mus musculus GN=Tbc1d10c PE=2 SV=1
Length = 444
Score = 72 bits (176), Expect = 2e-012
Identities = 38/92 (41%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Frame = +3
Query: 429 RKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDII-RDISRTFPSHVFF 605
RKGIP LR W L+ G+R NPG Y++L ++ I RD+ R FP H F
Sbjct: 88 RKGIPSALRARCWPLLCGARMCQKNNPGTYQELAAAPGDPQWMETIGRDLHRQFPLHEMF 147
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMG 701
G GQ+ L VLKAY++Y + GY Q G
Sbjct: 148 VSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQG 179
>sp|Q8BYJ6|TBCD4_MOUSE TBC1 domain family member 4 OS=Mus musculus GN=Tbc1d4
PE=1 SV=2
Length = 1307
Score = 71 bits (173), Expect = 5e-012
Identities = 35/99 (35%), Positives = 61/99 (61%), Gaps = 6/99 (6%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYE------QLVVYETSASELDIIRDISRTF 587
+++G+P RG +WQ ++ L P ++ + ++ + +A + I+ D+ RTF
Sbjct: 924 LKEGVPKSRRGEIWQFLALQYRLRHRLPNKHQPPDTSYKELLKQLTAQQHAILVDLGRTF 983
Query: 588 PSHVFFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
P+H +F + G GQ SL+N+LKAYS+ D++VGY QG+ F
Sbjct: 984 PTHPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISF 1022
>sp|P97366|EVI5_MOUSE Ecotropic viral integration site 5 protein OS=Mus musculus
GN=Evi5 PE=1 SV=2
Length = 809
Score = 70 bits (171), Expect = 9e-012
Identities = 37/91 (40%), Positives = 59/91 (64%), Gaps = 3/91 (3%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPGVYEQLVVYETSASELDIIRDISRTFPSHVFF 605
+RKGIP R +VWQL+ ++ + + + Y +L+ TS E I RDI+RT+P H FF
Sbjct: 160 VRKGIPHHFRAIVWQLLCNAQSMTIKDQ--YSELLKM-TSPCEKLIRRDIARTYPEHNFF 216
Query: 606 QKRHGPGQRSLYNVLKAYSVYDRDVGYVQGM 698
+++ GQ L+NV+KAYS+ DR++ V+ +
Sbjct: 217 KEKDSLGQEVLFNVMKAYSLVDRELVTVRAV 247
>sp|Q86TI0|TBCD1_HUMAN TBC1 domain family member 1 OS=Homo sapiens GN=TBC1D1
PE=1 SV=2
Length = 1168
Score = 70 bits (170), Expect = 1e-011
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 8/100 (8%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPG-------VYEQLVVYETSASELDIIRDISRT 584
+ +G+P RG +W+ ++ L P Y++L+ TS I+ D+ RT
Sbjct: 797 VGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHA-ILIDLGRT 855
Query: 585 FPSHVFFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
FP+H +F + G GQ SLYN+LKAYS+ D++VGY QG+ F
Sbjct: 856 FPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSF 895
>sp|Q60949|TBCD1_MOUSE TBC1 domain family member 1 OS=Mus musculus GN=Tbc1d1
PE=2 SV=2
Length = 1255
Score = 69 bits (167), Expect = 3e-011
Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 8/100 (8%)
Frame = +3
Query: 426 IRKGIPDCLRGLVWQLISGSRDLLLMNPG-------VYEQLVVYETSASELDIIRDISRT 584
+ +G+P RG +W+ ++ L P Y++L+ TS I+ D+ RT
Sbjct: 884 VGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQPKDVPYKELLKKLTSQQHA-ILIDLGRT 942
Query: 585 FPSHVFFQKRHGPGQRSLYNVLKAYSVYDRDVGYVQGMGF 704
FP+H +F + G GQ SLYN+LKAYS+ D++VGY QG+ F
Sbjct: 943 FPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSF 982
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 234,619,297,094
Number of Sequences: 518415
Number of Extensions: 234619297094
Number of Successful Extensions: 1485043153
Number of sequences better than 0.0: 0
|
