BLASTX 7.6.2
Query= UN71573 /QuerySize=573
(572 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gall... 93 1e-018
sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo... 91 3e-018
sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus ... 90 1e-017
sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pong... 90 1e-017
sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Dani... 87 8e-017
sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member ... 85 3e-016
sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member ... 83 9e-016
sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13 OS=S... 75 3e-013
sp|Q9VLU5|WWOX_DROME WW domain-containing oxidoreductase OS=Dros... 66 1e-010
sp|O32291|YXNA_BACSU Uncharacterized oxidoreductase yxnA OS=Baci... 52 2e-006
>sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gallus gallus
GN=WWOX PE=2 SV=2
Length = 414
Score = 93 bits (229), Expect = 1e-018
Identities = 51/113 (45%), Positives = 70/113 (61%), Gaps = 6/113 (5%)
Frame = +1
Query: 223 IVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNIEAMELD 402
I+TG+ SGIG ETA+ A GA+V++A RN + +Q+ EW +EAM LD
Sbjct: 128 IITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWH----KAKVEAMTLD 183
Query: 403 LLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHL 561
L SL SV FA+A+ +++ PLH+L+ NA IF G + +EDG E QVNHL
Sbjct: 184 LASLRSVQNFAEAFKSKNMPLHILVCNAAIF--GSSWCLTEDGLESTFQVNHL 234
>sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo sapiens
GN=WWOX PE=1 SV=1
Length = 414
Score = 91 bits (225), Expect = 3e-018
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 6/113 (5%)
Frame = +1
Query: 223 IVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNIEAMELD 402
+VTG+ SGIG ETA+ A GAHV++A RN A E + + EW +EAM LD
Sbjct: 128 VVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWH----KAKVEAMTLD 183
Query: 403 LLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHL 561
L L SV FA+A+ A++ PLHVL+ NA FA+ ++DG E QVNHL
Sbjct: 184 LALLRSVQHFAEAFKAKNVPLHVLVCNAATFAL--PWSLTKDGLETTFQVNHL 234
>sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus musculus
GN=Wwox PE=1 SV=1
Length = 414
Score = 90 bits (221), Expect = 1e-017
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 6/113 (5%)
Frame = +1
Query: 223 IVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNIEAMELD 402
+VTG+ SGIG ETA+ A GAHV++A RN A E + + EW +EAM LD
Sbjct: 128 LVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWH----KAKVEAMTLD 183
Query: 403 LLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHL 561
L L SV FA+A+ A++ LHVL+ NAG FA+ ++DG E QVNHL
Sbjct: 184 LAVLRSVQHFAEAFKAKNVSLHVLVCNAGTFAL--PWGLTKDGLETTFQVNHL 234
>sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pongo abelii
GN=WWOX PE=2 SV=1
Length = 414
Score = 90 bits (221), Expect = 1e-017
Identities = 51/113 (45%), Positives = 68/113 (60%), Gaps = 6/113 (5%)
Frame = +1
Query: 223 IVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNIEAMELD 402
+VTG+ SGIG ETA+ A GAHV++A RN A E + + EW +EA+ LD
Sbjct: 128 VVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWH----KAKVEAVTLD 183
Query: 403 LLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHL 561
L L SV FA+A+ A++ PLHVL+ NA FA+ ++DG E QVNHL
Sbjct: 184 LALLRSVQHFAEAFKAKNVPLHVLVCNAATFAL--PWSLTKDGLETTFQVNHL 234
>sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Danio rerio GN=wwox
PE=2 SV=1
Length = 412
Score = 87 bits (213), Expect = 8e-017
Identities = 49/119 (41%), Positives = 68/119 (57%), Gaps = 6/119 (5%)
Frame = +1
Query: 205 VNDLTCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNI 384
++D IVTG+ SGIG ETAR A GAHV++A RN A + EW+ +
Sbjct: 119 LSDKVIIVTGANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWS----KARV 174
Query: 385 EAMELDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHL 561
E + LDL SL SV +FA+ + A PLHVL+ NA + + + +EDG+E Q+ HL
Sbjct: 175 EVLPLDLASLRSVRQFAELFKATKLPLHVLVCNAAV--CSQPWRLTEDGFESTFQICHL 231
>sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member on chromosome X
homolog OS=Mus musculus GN=Dhrsx PE=2 SV=2
Length = 335
Score = 85 bits (208), Expect = 3e-016
Identities = 54/125 (43%), Positives = 72/125 (57%), Gaps = 6/125 (4%)
Frame = +1
Query: 187 PLPLPPVNDLTCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGR 366
P LPP IVTG+T+GIGR TARQLA G VV+A + QE++ + E
Sbjct: 35 PPVLPPQPGRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEMGSD 94
Query: 367 GLPLNIEAMELDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHM 546
+ LDL SLASV FA + A PLH+L++NAG+ M E + +EDG+E+H+
Sbjct: 95 ----RAHFLPLDLASLASVRGFARDFQALGLPLHLLVNNAGV--MLEPRAETEDGFERHL 148
Query: 547 QVNHL 561
VN L
Sbjct: 149 GVNFL 153
>sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X
OS=Homo sapiens GN=DHRSX PE=2 SV=2
Length = 330
Score = 83 bits (204), Expect = 9e-016
Identities = 46/121 (38%), Positives = 70/121 (57%), Gaps = 6/121 (4%)
Frame = +1
Query: 199 PPVNDLTCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPL 378
PP D IVTG T GIG TA+ LA G HV++A N A++++ + + E L
Sbjct: 39 PPRPDRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEE----TLND 94
Query: 379 NIEAMELDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNH 558
+E + DL S+ S+ +F + + PLHVLI+NAG+ M Q+ + DG+E+H +N+
Sbjct: 95 KVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGV--MMVPQRKTRDGFEEHFGLNY 152
Query: 559 L 561
L
Sbjct: 153 L 153
>sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13
OS=Schizosaccharomyces pombe GN=SPCC736.13 PE=2 SV=1
Length = 339
Score = 75 bits (182), Expect = 3e-013
Identities = 45/123 (36%), Positives = 72/123 (58%), Gaps = 6/123 (4%)
Frame = +1
Query: 196 LPPVNDLTCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLP 375
+P + +VTGS+ GIG TA +LA GA V +A RN + Q++++Q +E
Sbjct: 37 IPDLTGKVALVTGSSGGIGYVTALELARKGAKVYLAGRNEEKYQKVMKQIHDEVRHS--- 93
Query: 376 LNIEAMELDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVN 555
I + LDLL SV + A+++ A+ LH+L++NAGI M + ++DGYE +Q N
Sbjct: 94 -KIRFLRLDLLDFESVYQAAESFIAKEEKLHILVNNAGI--MNPPFELTKDGYELQIQTN 150
Query: 556 HLA 564
+L+
Sbjct: 151 YLS 153
>sp|Q9VLU5|WWOX_DROME WW domain-containing oxidoreductase OS=Drosophila
melanogaster GN=Wwox PE=2 SV=1
Length = 409
Score = 66 bits (159), Expect = 1e-010
Identities = 43/116 (37%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Frame = +1
Query: 217 TCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNEWTGRGLPLNIEAME 396
T ++TG+ GIG ETAR LA G ++ A RN +A+ I++ E A
Sbjct: 123 TALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAA-- 180
Query: 397 LDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFSEDGYEQHMQVNHLA 564
LDL SL SV RF + + LI NAG+FA+ + + DG E QV+HL+
Sbjct: 181 LDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTR--TVDGLETTFQVSHLS 234
>sp|O32291|YXNA_BACSU Uncharacterized oxidoreductase yxnA OS=Bacillus subtilis
GN=yxnA PE=3 SV=2
Length = 356
Score = 52 bits (124), Expect = 2e-006
Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 16/135 (11%)
Frame = +1
Query: 178 LQNPLPLPPVNDLTCIVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELIQQWQNE- 354
++ L L + D ++TG++SGIG TAR AE GA VV A RN +A +EL + + +
Sbjct: 20 IKTKLKLKKLKDQVIVITGASSGIGLVTARMAAEKGAKVVAAARNEEALKELTDELKEKG 79
Query: 355 ----WTGRGLPLNIEAMELDLLSLASVARFADAWNARSGPLHVLIDNAGIFAMGEAQKFS 522
W + + + ++++ RF D W ++NA + G A +
Sbjct: 80 HDAIWVKADVGKEEDVNRIAETAISTFGRF-DTW----------VNNAAVSTFGHAMDVT 128
Query: 523 EDGYEQHMQVNHLAP 567
+ ++ N P
Sbjct: 129 VEDMKRMFDTNFWGP 143
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 238,032,376,884
Number of Sequences: 518415
Number of Extensions: 238032376884
Number of Successful Extensions: 1500547491
Number of sequences better than 0.0: 0
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