BLASTX 7.6.2
Query= UN72731 /QuerySize=765
(764 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A6QP05|DHR12_BOVIN Dehydrogenase/reductase SDR family member ... 156 2e-037
sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member ... 153 2e-036
sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens G... 126 3e-028
sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus G... 121 5e-027
sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus G... 117 1e-025
sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=... 116 2e-025
sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens G... 115 4e-025
sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens G... 109 3e-023
sp|Q17QU7|DHR13_BOVIN Dehydrogenase/reductase SDR family member ... 108 6e-023
sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus G... 108 6e-023
sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member ... 107 1e-022
sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member ... 106 2e-022
sp|Q5SS80|DHR13_MOUSE Dehydrogenase/reductase SDR family member ... 105 4e-022
sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gall... 105 4e-022
sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo... 100 2e-020
sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pong... 100 2e-020
sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member ... 99 2e-020
sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus ... 98 6e-020
sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13 OS=S... 95 5e-019
sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Dani... 94 1e-018
>sp|A6QP05|DHR12_BOVIN Dehydrogenase/reductase SDR family member 12 OS=Bos
taurus GN=DHRS12 PE=2 SV=1
Length = 317
Score = 156 bits (392), Expect = 2e-037
Identities = 80/182 (43%), Positives = 115/182 (63%), Gaps = 2/182 (1%)
Frame = +2
Query: 116 WRSTAFGIYGYMNFTKNGFLDHSKKFKPEDMQIQIQGKNCVVTGANSGIGYAAAEGLASR 295
+RS A+ G +TK+G+ SK F P+D+++Q+ G+ +VTG NSGIG A A +A R
Sbjct: 4 YRSAAWFAKGLREYTKSGYESASKDFVPDDLEVQVPGRAFMVTGGNSGIGKATAMEIAKR 63
Query: 296 GANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCDLSSVNDIKSFASTFASKDVPVHVL 475
G V++VCR+ R E A ++I +GNQN++L + DLS + F F ++ ++VL
Sbjct: 64 GGTVHLVCRDHSRAEGAKAEIIRESGNQNIFLHIVDLSLPKSVWKFVENF-KQEHTLNVL 122
Query: 476 VNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELMLPLLEKASPDSKVITVSSGGMYTS 655
+NNAG + NKR T +G E NFA N LG Y +T ++P+LEK D +VITVSSGGM
Sbjct: 123 INNAGCMVNKRELTEDGLEKNFATNTLGVYVLTTALIPVLEK-EHDPRVITVSSGGMLVQ 181
Query: 656 PL 661
L
Sbjct: 182 KL 183
>sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member 12 OS=Homo
sapiens GN=DHRS12 PE=2 SV=2
Length = 317
Score = 153 bits (384), Expect = 2e-036
Identities = 80/185 (43%), Positives = 113/185 (61%), Gaps = 2/185 (1%)
Frame = +2
Query: 107 LKTWRSTAFGIYGYMNFTKNGFLDHSKKFKPEDMQIQIQGKNCVVTGANSGIGYAAAEGL 286
+ +RS + G +TK+G+ K F P D+++QI G+ +VTG NSGIG A A +
Sbjct: 1 MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEI 60
Query: 287 ASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCDLSSVNDIKSFASTFASKDVPV 466
A RG V++VCR++ E+A +I +GNQN++L + DLS I F F ++ +
Sbjct: 61 AKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENF-KQEHKL 119
Query: 467 HVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELMLPLLEKASPDSKVITVSSGGM 646
HVL+NNAG + NKR T +G E NFA N LG Y +T ++P+LEK D +VITVSSGGM
Sbjct: 120 HVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEK-EHDPRVITVSSGGM 178
Query: 647 YTSPL 661
L
Sbjct: 179 LVQKL 183
>sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens GN=RDH11 PE=1
SV=2
Length = 318
Score = 126 bits (314), Expect = 3e-028
Identities = 63/142 (44%), Positives = 96/142 (67%), Gaps = 1/142 (0%)
Frame = +2
Query: 212 IQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYL 391
+Q+ GK VVTGAN+GIG A+ LA RGA VY+ CR+ E+GE +IQ +TGNQ V +
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLV 96
Query: 392 EVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTM 571
DLS I++FA F +++ +HVL+NNAG++ + T +GFE++ VN LG + +
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLL 156
Query: 572 TELMLPLLEKASPDSKVITVSS 637
T L+L L++++P S+++ VSS
Sbjct: 157 THLLLEKLKESAP-SRIVNVSS 177
>sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus GN=Rdh11 PE=2
SV=2
Length = 316
Score = 121 bits (303), Expect = 5e-027
Identities = 59/144 (40%), Positives = 97/144 (67%), Gaps = 1/144 (0%)
Frame = +2
Query: 212 IQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYL 391
+Q+ GK +VTGAN+GIG A+ LA RGA VY+ CR+ ++GE A +IQ TGN V++
Sbjct: 34 VQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFV 93
Query: 392 EVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTM 571
DL+ I++FA F +++ +H+L+NNAG++ + T +GFE++ VN LG + +
Sbjct: 94 RKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLL 153
Query: 572 TELMLPLLEKASPDSKVITVSSGG 643
T L+L L++++P S+++ +SS G
Sbjct: 154 THLLLEKLKESAP-SRIVNLSSLG 176
>sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus GN=Rdh12 PE=2
SV=1
Length = 316
Score = 117 bits (292), Expect = 1e-025
Identities = 60/142 (42%), Positives = 93/142 (65%), Gaps = 1/142 (0%)
Frame = +2
Query: 212 IQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYL 391
+QI GK V+TGAN+GIG A LA RGA VY+ CR+ +GE A S+I+ T N V +
Sbjct: 35 VQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLV 94
Query: 392 EVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTM 571
DLS I++FA F +++ +H+L+NNAG++ + T +GFE +F VN LG + +
Sbjct: 95 RKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTTDGFETHFGVNHLGHFLL 154
Query: 572 TELMLPLLEKASPDSKVITVSS 637
T L+L L++++P ++V+ +SS
Sbjct: 155 TYLLLERLKESAP-ARVVNLSS 175
>sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=RDH12 PE=2
SV=1
Length = 316
Score = 116 bits (289), Expect = 2e-025
Identities = 60/142 (42%), Positives = 93/142 (65%), Gaps = 1/142 (0%)
Frame = +2
Query: 212 IQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYL 391
+Q+ GK V+TGAN+GIG A LA RGA VY+ CR+ +GE A S+IQ T N V +
Sbjct: 35 VQLFGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIQADTKNSQVLV 94
Query: 392 EVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTM 571
DLS I++FA F +++ +H+L+NNAG++ + T +GFE + AVN LG + +
Sbjct: 95 RKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMLCPYSKTADGFETHLAVNHLGHFLL 154
Query: 572 TELMLPLLEKASPDSKVITVSS 637
T L+L L++++P ++V+ +SS
Sbjct: 155 THLLLGRLKESAP-ARVVNLSS 175
>sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens GN=RDH12 PE=1
SV=3
Length = 316
Score = 115 bits (287), Expect = 4e-025
Identities = 60/142 (42%), Positives = 92/142 (64%), Gaps = 1/142 (0%)
Frame = +2
Query: 212 IQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYL 391
+Q+ GK V+TGAN+GIG A LASRGA VY+ CR+ +GE A S+I+ T N V +
Sbjct: 35 VQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLV 94
Query: 392 EVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTM 571
DLS I++FA F +++ +H+L+NNAG++ + T +GFE + VN LG + +
Sbjct: 95 RKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLL 154
Query: 572 TELMLPLLEKASPDSKVITVSS 637
T L+L L+ ++P ++V+ VSS
Sbjct: 155 TYLLLERLKVSAP-ARVVNVSS 175
>sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens GN=RDH13 PE=1
SV=2
Length = 331
Score = 109 bits (270), Expect = 3e-023
Identities = 59/140 (42%), Positives = 85/140 (60%), Gaps = 1/140 (0%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
I GK +VTGAN+GIG A LA RG N+ + CR+ E+ E A I+ T N +V
Sbjct: 36 IPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARH 95
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ I+ FA+ ++ V +L+NNAG++ TT +GFE+ F VN LG + +T
Sbjct: 96 LDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTN 155
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+L L KAS S++I +SS
Sbjct: 156 LLLDKL-KASAPSRIINLSS 174
>sp|Q17QU7|DHR13_BOVIN Dehydrogenase/reductase SDR family member 13 OS=Bos
taurus GN=DHRS13 PE=2 SV=1
Length = 377
Score = 108 bits (268), Expect = 6e-023
Identities = 58/140 (41%), Positives = 88/140 (62%), Gaps = 3/140 (2%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
++G+ VVTGANSGIG A LA RGA V + CR++ERGE A ++ +GN V
Sbjct: 34 LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMA 93
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ +++FA+ F S + + +L++NAG+ RT P F L VN +G + +T
Sbjct: 94 LDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREP--FNLLLRVNHIGPFLLTH 151
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+LP L+ ++P S+V+ VSS
Sbjct: 152 LLLPRLKTSAP-SRVVVVSS 170
>sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus GN=Rdh13 PE=2
SV=1
Length = 334
Score = 108 bits (268), Expect = 6e-023
Identities = 61/140 (43%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
I GK +VTGAN+GIG A LA RG NV + CR+ E+ E A I+ T N V E
Sbjct: 36 IPGKTVIVTGANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGETLNPRVRAER 95
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ I+ FA ++ V +LVNNA ++ TT +GFE+ F VN LG + +T
Sbjct: 96 LDLASLKSIREFARKVIKEEERVDILVNNAAVMRCPHWTTEDGFEMQFGVNYLGHFLLTN 155
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+L L KAS S++I +SS
Sbjct: 156 LLLDKL-KASAPSRIINLSS 174
>sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X
OS=Homo sapiens GN=DHRSX PE=2 SV=2
Length = 330
Score = 107 bits (265), Expect = 1e-022
Identities = 57/145 (39%), Positives = 86/145 (59%), Gaps = 3/145 (2%)
Frame = +2
Query: 236 VVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCDLSSV 415
+VTG GIGY+ A+ LA G +V + N + ++ +SKI+ T N V CDL+S+
Sbjct: 47 IVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 416 NDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELMLPLL 595
I+ F F K +P+HVL+NNAG++ + T +GFE +F +N LG + +T L+L L
Sbjct: 107 TSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLLDTL 166
Query: 596 -EKASP--DSKVITVSSGGMYTSPL 661
E SP ++V+TVSS Y + L
Sbjct: 167 KESGSPGHSARVVTVSSATHYVAEL 191
>sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 OS=Homo
sapiens GN=DHRS13 PE=1 SV=1
Length = 377
Score = 106 bits (263), Expect = 2e-022
Identities = 57/140 (40%), Positives = 87/140 (62%), Gaps = 3/140 (2%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
++G+ VVTGANSGIG A LA RGA V + CR++ERGE A ++ +GN V
Sbjct: 34 LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMA 93
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ +++FA+ F S + + +L++NAG+ RT E F L VN +G + +T
Sbjct: 94 LDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTR--EAFNLLLRVNHIGPFLLTH 151
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+LP L+ +P S+V+ V+S
Sbjct: 152 LLLPCLKACAP-SRVVVVAS 170
>sp|Q5SS80|DHR13_MOUSE Dehydrogenase/reductase SDR family member 13 OS=Mus
musculus GN=Dhrs13 PE=1 SV=1
Length = 376
Score = 105 bits (261), Expect = 4e-022
Identities = 59/140 (42%), Positives = 86/140 (61%), Gaps = 3/140 (2%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
++G+ VVTGANSGIG A LA RGA V + CR++ERGE A ++ +GN V
Sbjct: 34 LRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMA 93
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ +++FA+ F S + + VL++NAG+ RT E F L VN +G + +T
Sbjct: 94 LDLASLASVQAFATAFLSSEPRLDVLIHNAGISSCGRTR--ETFNLLLRVNHVGPFLLTH 151
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+LP L +P S+V+ VSS
Sbjct: 152 LLLPRLRSCAP-SRVVIVSS 170
>sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gallus gallus
GN=WWOX PE=2 SV=2
Length = 414
Score = 105 bits (261), Expect = 4e-022
Identities = 53/140 (37%), Positives = 84/140 (60%), Gaps = 1/140 (0%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
+ GK ++TGANSGIG+ A+ A GA V + CRN RG +A+ +I V
Sbjct: 122 LSGKVIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKAKVEAMT 181
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ +++FA F SK++P+H+LV NA + + T +G E F VN LG + + +
Sbjct: 182 LDLASLRSVQNFAEAFKSKNMPLHILVCNAAIFGSSWCLTEDGLESTFQVNHLGHFYLVQ 241
Query: 578 LMLPLLEKASPDSKVITVSS 637
L+ +L ++SP ++V+ VSS
Sbjct: 242 LLEDILRRSSP-ARVVVVSS 260
>sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo sapiens
GN=WWOX PE=1 SV=1
Length = 414
Score = 100 bits (247), Expect = 2e-020
Identities = 56/138 (40%), Positives = 81/138 (58%), Gaps = 1/138 (0%)
Frame = +2
Query: 224 GKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCD 403
GK VVTGANSGIG+ A+ A GA+V + CRN R EA+S+I V D
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLD 183
Query: 404 LSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELM 583
L+ + ++ FA F +K+VP+HVLV NA + T +G E F VN LG + + +L+
Sbjct: 184 LALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLL 243
Query: 584 LPLLEKASPDSKVITVSS 637
+L +++P ++VI VSS
Sbjct: 244 QDVLCRSAP-ARVIVVSS 260
>sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pongo abelii
GN=WWOX PE=2 SV=1
Length = 414
Score = 100 bits (247), Expect = 2e-020
Identities = 56/138 (40%), Positives = 81/138 (58%), Gaps = 1/138 (0%)
Frame = +2
Query: 224 GKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCD 403
GK VVTGANSGIG+ A+ A GA+V + CRN R EA+S+I V D
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAVTLD 183
Query: 404 LSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELM 583
L+ + ++ FA F +K+VP+HVLV NA + T +G E F VN LG + + +L+
Sbjct: 184 LALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLL 243
Query: 584 LPLLEKASPDSKVITVSS 637
+L +++P ++VI VSS
Sbjct: 244 QDVLCRSAP-ARVIVVSS 260
>sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member on chromosome X
homolog OS=Mus musculus GN=Dhrsx PE=2 SV=2
Length = 335
Score = 99 bits (246), Expect = 2e-020
Identities = 56/156 (35%), Positives = 89/156 (57%), Gaps = 4/156 (2%)
Frame = +2
Query: 191 FKPEDMQIQIQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNST 370
F+P + Q G+ +VTGA +GIG + A LA G V + ++ RG+E +S I+
Sbjct: 33 FRPPVLPPQ-PGRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEM 91
Query: 371 GNQNVYLEVCDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVN 550
G+ + DL+S+ ++ FA F + +P+H+LVNNAG++ R T +GFE + VN
Sbjct: 92 GSDRAHFLPLDLASLASVRGFARDFQALGLPLHLLVNNAGVMLEPRAETEDGFERHLGVN 151
Query: 551 VLGTYTMTELMLPLLEKASPD---SKVITVSSGGMY 649
LG + +T L+LP L + + S+V+TV S Y
Sbjct: 152 FLGHFLLTLLLLPALRASGAEGRGSRVVTVGSATHY 187
>sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus musculus
GN=Wwox PE=1 SV=1
Length = 414
Score = 98 bits (242), Expect = 6e-020
Identities = 56/138 (40%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +2
Query: 224 GKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEVCD 403
GK +VTGANSGIG+ A+ A GA+V + CRN R EA+S+I V D
Sbjct: 124 GKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAKVEAMTLD 183
Query: 404 LSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTELM 583
L+ + ++ FA F +K+V +HVLV NAG T +G E F VN LG + + +L+
Sbjct: 184 LAVLRSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLL 243
Query: 584 LPLLEKASPDSKVITVSS 637
+L ++SP ++VI VSS
Sbjct: 244 QDVLCRSSP-ARVIVVSS 260
>sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13
OS=Schizosaccharomyces pombe GN=SPCC736.13 PE=2 SV=1
Length = 339
Score = 95 bits (234), Expect = 5e-019
Identities = 50/157 (31%), Positives = 85/157 (54%), Gaps = 5/157 (3%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
+ GK +VTG++ GIGY A LA +GA VY+ RN+E+ ++ + +I + + +
Sbjct: 40 LTGKVALVTGSSGGIGYVTALELARKGAKVYLAGRNEEKYQKVMKQIHDEVRHSKIRFLR 99
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL + A +F +K+ +H+LVNNAG++ T +G+EL N L Y TE
Sbjct: 100 LDLLDFESVYQAAESFIAKEEKLHILVNNAGIMNPPFELTKDGYELQIQTNYLSHYLFTE 159
Query: 578 LMLPLLEKASP-----DSKVITVSSGGMYTSPLTQIF 673
L+LP L + + D +++ V+S +P + I+
Sbjct: 160 LLLPTLRRTAEECRPGDVRIVHVASIAYLQAPYSGIY 196
>sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Danio rerio GN=wwox
PE=2 SV=1
Length = 412
Score = 94 bits (231), Expect = 1e-018
Identities = 51/158 (32%), Positives = 80/158 (50%)
Frame = +2
Query: 218 IQGKNCVVTGANSGIGYAAAEGLASRGANVYMVCRNKERGEEALSKIQNSTGNQNVYLEV 397
+ K +VTGANSGIG+ A A GA+V + CRN+ R +A S I V +
Sbjct: 119 LSDKVIIVTGANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWSKARVEVLP 178
Query: 398 CDLSSVNDIKSFASTFASKDVPVHVLVNNAGLLENKRTTTPEGFELNFAVNVLGTYTMTE 577
DL+S+ ++ FA F + +P+HVLV NA + T +GFE F + LG + + +
Sbjct: 179 LDLASLRSVRQFAELFKATKLPLHVLVCNAAVCSQPWRLTEDGFESTFQICHLGHFLLVQ 238
Query: 578 LMLPLLEKASPDSKVITVSSGGMYTSPLTQIFSYQSDI 691
L+ +L ++P V+ S +T L + D+
Sbjct: 239 LLQDVLRLSAPARVVVVSSESHRFTDLLDSCGNLDLDL 276
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 239,620,709,007
Number of Sequences: 518415
Number of Extensions: 239620709007
Number of Successful Extensions: 1524707197
Number of sequences better than 0.0: 0
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