BLASTX 7.6.2
Query= UN73512 /QuerySize=683
(682 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZL16|WIPI3_CHICK WD repeat domain phosphoinositide-interact... 112 3e-024
sp|Q68F45|WIPI3_XENLA WD repeat domain phosphoinositide-interact... 111 4e-024
sp|Q640T2|WIPI3_XENTR WD repeat domain phosphoinositide-interact... 111 4e-024
sp|Q5MNZ6|WIPI3_HUMAN WD repeat domain phosphoinositide-interact... 111 8e-024
sp|Q9CR39|WIPI3_MOUSE WD repeat domain phosphoinositide-interact... 111 8e-024
sp|Q5R7W0|WIPI3_PONAB WD repeat domain phosphoinositide-interact... 111 8e-024
sp|Q7ZUW6|WIPI3_DANRE WD repeat domain phosphoinositide-interact... 110 1e-023
sp|Q5QA93|HSV2_PICAN SVP1-like protein 2 OS=Pichia angusta GN=HS... 91 6e-018
sp|Q6CEI9|HSV2_YARLI SVP1-like protein 2 OS=Yarrowia lipolytica ... 91 6e-018
sp|Q9P3W2|HSV2_SCHPO SVP1-like protein 2 OS=Schizosaccharomyces ... 80 8e-015
sp|Q91VM3|WIPI4_MOUSE WD repeat domain phosphoinositide-interact... 79 2e-014
sp|Q5U2Y0|WIPI4_RAT WD repeat domain phosphoinositide-interactin... 79 2e-014
sp|Q9Y484|WIPI4_HUMAN WD repeat domain phosphoinositide-interact... 78 5e-014
sp|Q6DCV0|WIPI4_XENLA WD repeat domain phosphoinositide-interact... 77 9e-014
sp|Q6FXC1|HSV2_CANGA SVP1-like protein 2 OS=Candida glabrata GN=... 72 2e-012
sp|Q7ZUX3|WIPI4_DANRE WD repeat domain phosphoinositide-interact... 71 7e-012
sp|Q9FPQ6|GP1_CHLRE Vegetative cell wall protein gp1 OS=Chlamydo... 62 2e-009
>sp|Q5ZL16|WIPI3_CHICK WD repeat domain phosphoinositide-interacting protein 3
OS=Gallus gallus GN=WDR45L PE=2 SV=1
Length = 344
Score = 112 bits (279), Expect = 3e-024
Identities = 55/100 (55%), Positives = 66/100 (66%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNADPLKEKEKQEFPE-GGVGHVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q68F45|WIPI3_XENLA WD repeat domain phosphoinositide-interacting protein 3
OS=Xenopus laevis GN=wdr45l PE=2 SV=1
Length = 344
Score = 111 bits (277), Expect = 4e-024
Identities = 55/100 (55%), Positives = 67/100 (67%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV+ VEM
Sbjct: 7 NPHGN------GLLYSGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEF-LEGGVSYVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q640T2|WIPI3_XENTR WD repeat domain phosphoinositide-interacting protein 3
OS=Xenopus tropicalis GN=wdr45l PE=2 SV=1
Length = 344
Score = 111 bits (277), Expect = 4e-024
Identities = 55/100 (55%), Positives = 66/100 (66%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEF-LEGGVGYVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q5MNZ6|WIPI3_HUMAN WD repeat domain phosphoinositide-interacting protein 3
OS=Homo sapiens GN=WDR45L PE=2 SV=2
Length = 344
Score = 111 bits (275), Expect = 8e-024
Identities = 55/100 (55%), Positives = 66/100 (66%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEF-LEGGVGHVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q9CR39|WIPI3_MOUSE WD repeat domain phosphoinositide-interacting protein 3
OS=Mus musculus GN=Wdr45l PE=2 SV=2
Length = 344
Score = 111 bits (275), Expect = 8e-024
Identities = 55/100 (55%), Positives = 66/100 (66%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEF-LEGGVGHVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q5R7W0|WIPI3_PONAB WD repeat domain phosphoinositide-interacting protein 3
OS=Pongo abelii GN=WDR45L PE=2 SV=1
Length = 344
Score = 111 bits (275), Expect = 8e-024
Identities = 55/100 (55%), Positives = 66/100 (66%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E +++F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEF-LEGGVGHVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q7ZUW6|WIPI3_DANRE WD repeat domain phosphoinositide-interacting protein 3
OS=Danio rerio GN=wdr45l PE=2 SV=1
Length = 344
Score = 110 bits (274), Expect = 1e-023
Identities = 55/100 (55%), Positives = 65/100 (65%), Gaps = 7/100 (7%)
Frame = +1
Query: 262 NPDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEM 441
NP N LL+ FNQDH CFA G + GFR+ N DP +E + +F GGV VEM
Sbjct: 7 NPHGN------GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKHEF-LEGGVGHVEM 59
Query: 442 LFRCNILALVGGGPDPQYPPNKVMIWDDHQSPCIGELSFS 561
LFRCN LALVGGG P+YPPNKVMIWDD + + E+ FS
Sbjct: 60 LFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFS 99
>sp|Q5QA93|HSV2_PICAN SVP1-like protein 2 OS=Pichia angusta GN=HSV2 PE=3 SV=1
Length = 360
Score = 91 bits (224), Expect = 6e-018
Identities = 46/109 (42%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
Frame = +1
Query: 265 PDSNIQTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEML 444
P +++ P++L+ +FNQD CFAV + GF++ N DP +R F GGV ++ ML
Sbjct: 6 PIESVRAHEPAVLNAAFNQDQTCFAVCHESGFQVYNTDPMELRMKRTFSTNGGVGLIAML 65
Query: 445 FRCNILALVGGGPDPQYPPNKVMIWDD-HQSPCIGELSFSPMFDPLGSR 588
R N +ALVGGG P++P NK+ IWDD + P I SP+ + L SR
Sbjct: 66 HRTNYVALVGGGRQPRFPVNKLCIWDDLKKKPSIMLEFMSPILNVLLSR 114
>sp|Q6CEI9|HSV2_YARLI SVP1-like protein 2 OS=Yarrowia lipolytica GN=HSV2 PE=3
SV=1
Length = 359
Score = 91 bits (224), Expect = 6e-018
Identities = 48/111 (43%), Positives = 73/111 (65%), Gaps = 4/111 (3%)
Frame = +1
Query: 265 PDSNIQTPLPS--LLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVE 438
PD+++ + +L+ +FNQD ACFA+ +RGFR+ DP +R+FD GG+ V++
Sbjct: 4 PDAHVIASMEDQPILNAAFNQDSACFAICHNRGFRVYVTDPMDLRVQREFD-DGGIGVIQ 62
Query: 439 MLFRCNILALVGGGPDPQYPPNKVMIWDDHQS-PCIGELSFSPMFDPLGSR 588
ML R N LA+VGGG +P++P NK++IWDD +S P + SP+ + L SR
Sbjct: 63 MLHRTNYLAVVGGGSNPKFPQNKLVIWDDLKSKPALSLEFLSPVLNVLLSR 113
>sp|Q9P3W2|HSV2_SCHPO SVP1-like protein 2 OS=Schizosaccharomyces pombe GN=hsv2
PE=2 SV=1
Length = 364
Score = 80 bits (197), Expect = 8e-015
Identities = 36/85 (42%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Frame = +1
Query: 307 LSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPD 486
+S NQD +C +V D G++I +P + +R F+ GG+++V+MLFR N+L LVGGG +
Sbjct: 7 VSLNQDASCMSVALDTGYKIFQINPLKLRAQRQFN-DGGLSIVKMLFRSNVLLLVGGGGN 65
Query: 487 PQYPPNKVMIWDDHQSPCIGELSFS 561
P+Y PNK+++WDD + + EL +
Sbjct: 66 PKYAPNKLIVWDDVKERPVKELELN 90
>sp|Q91VM3|WIPI4_MOUSE WD repeat domain phosphoinositide-interacting protein 4
OS=Mus musculus GN=Wdr45 PE=2 SV=1
Length = 360
Score = 79 bits (193), Expect = 2e-014
Identities = 38/82 (46%), Positives = 49/82 (59%)
Frame = +1
Query: 280 QTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNI 459
Q PL + L FNQD +CF + G RI N +P E D ++ G V +VEML R N+
Sbjct: 3 QQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNL 62
Query: 460 LALVGGGPDPQYPPNKVMIWDD 525
LALVGGG P++ V+IWDD
Sbjct: 63 LALVGGGSSPKFSEISVLIWDD 84
>sp|Q5U2Y0|WIPI4_RAT WD repeat domain phosphoinositide-interacting protein 4
OS=Rattus norvegicus GN=Wdr45 PE=2 SV=1
Length = 309
Score = 79 bits (193), Expect = 2e-014
Identities = 38/82 (46%), Positives = 49/82 (59%)
Frame = +1
Query: 280 QTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNI 459
Q PL + L FNQD +CF + G RI N +P E D ++ G V +VEML R N+
Sbjct: 3 QQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNL 62
Query: 460 LALVGGGPDPQYPPNKVMIWDD 525
LALVGGG P++ V+IWDD
Sbjct: 63 LALVGGGSSPKFSEISVLIWDD 84
>sp|Q9Y484|WIPI4_HUMAN WD repeat domain phosphoinositide-interacting protein 4
OS=Homo sapiens GN=WDR45 PE=2 SV=1
Length = 360
Score = 78 bits (190), Expect = 5e-014
Identities = 37/82 (45%), Positives = 49/82 (59%)
Frame = +1
Query: 280 QTPLPSLLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNI 459
Q PL + L FNQD +CF + G RI N +P E D ++ G + +VEML R N+
Sbjct: 3 QQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNL 62
Query: 460 LALVGGGPDPQYPPNKVMIWDD 525
LALVGGG P++ V+IWDD
Sbjct: 63 LALVGGGSSPKFSEISVLIWDD 84
>sp|Q6DCV0|WIPI4_XENLA WD repeat domain phosphoinositide-interacting protein 4
OS=Xenopus laevis GN=wdr45 PE=2 SV=1
Length = 355
Score = 77 bits (188), Expect = 9e-014
Identities = 36/73 (49%), Positives = 46/73 (63%)
Frame = +1
Query: 307 LSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPD 486
L FNQD +CF + G RI N +P E D ++ G V VEML RCN+LALVGGG +
Sbjct: 10 LRFNQDQSCFCCAMETGVRIFNIEPLMEKGHLDQEQVGSVGQVEMLHRCNLLALVGGGSN 69
Query: 487 PQYPPNKVMIWDD 525
P++ V+IWDD
Sbjct: 70 PKFSDISVLIWDD 82
>sp|Q6FXC1|HSV2_CANGA SVP1-like protein 2 OS=Candida glabrata GN=HSV2 PE=3 SV=1
Length = 445
Score = 72 bits (176), Expect = 2e-012
Identities = 33/79 (41%), Positives = 50/79 (63%), Gaps = 4/79 (5%)
Frame = +1
Query: 307 LSFNQDHACFAVGTDRGFRILNCDPFREIFRRDF----DRGGGVAVVEMLFRCNILALVG 474
++FNQD +CF+ ++GF + N P ++F +RG G+ +ML+R N +ALVG
Sbjct: 20 VTFNQDESCFSCANEQGFLVYNTFPLSLKLTKEFKQTPERGAGIGYSQMLYRTNYIALVG 79
Query: 475 GGPDPQYPPNKVMIWDDHQ 531
GG P+Y N+V+IWDD Q
Sbjct: 80 GGQRPRYSLNRVVIWDDLQ 98
>sp|Q7ZUX3|WIPI4_DANRE WD repeat domain phosphoinositide-interacting protein 4
OS=Danio rerio GN=wdr45 PE=2 SV=1
Length = 358
Score = 71 bits (172), Expect = 7e-012
Identities = 32/73 (43%), Positives = 45/73 (61%)
Frame = +1
Query: 307 LSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPD 486
L FNQD +CF + G RI N +P E D ++ G +A+ ML R N+LA+VGGG +
Sbjct: 10 LQFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSIALCSMLHRSNLLAVVGGGVN 69
Query: 487 PQYPPNKVMIWDD 525
P++ V+IWDD
Sbjct: 70 PKFSEISVLIWDD 82
>sp|Q9FPQ6|GP1_CHLRE Vegetative cell wall protein gp1 OS=Chlamydomonas
reinhardtii GN=GP1 PE=2 SV=1
Length = 555
Score = 62 bits (150), Expect = 2e-009
Identities = 47/121 (38%), Positives = 57/121 (47%), Gaps = 8/121 (6%)
Frame = +2
Query: 74 PPSPLPPTLLPGQSIPPPPQIPTLLSPLTTAIPETTPSPSIPSPP*ASTPKRSLTIPIPI 253
PPSP PP+ P PP P P+ P + P + PSP+ PSP + P S P P
Sbjct: 88 PPSPAPPSPAPPSPAPPSPAPPSPAPP--SPAPPSPPSPAPPSPSPPAPPSPSPPSPAP- 144
Query: 254 PIPIPIPTSKRLSPPSFTSPSTKTTPA-SPSAPTAASASSTAIPSARFSAAISIAAAVSP 430
P+P P P SPP SPS P+ +P +PT S S PS A S A V P
Sbjct: 145 PLP-PSPAPPSPSPPVPPSPSPPVPPSPAPPSPTPPSPSPPVPPS---PAPPSPAPPVPP 200
Query: 431 S 433
S
Sbjct: 201 S 201
Score = 60 bits (145), Expect = 9e-009
Identities = 40/113 (35%), Positives = 49/113 (43%), Gaps = 11/113 (9%)
Frame = +2
Query: 74 PPSPLPPTLLPGQSIPPPPQIPTLLSPLTTAIPETTPSPSIPSPP*ASTPKRSLTIPIPI 253
PPSP PP+ P PP P P SP + +P+P P+PP + P + P P
Sbjct: 60 PPSPAPPSPGPPSPAPPSPPSPAPPSPAPPSPAPPSPAPPSPAPPSPAPPSPAPPSPAPP 119
Query: 254 PIPIPIPTSKRLSPPSFTSPSTKT---------TPASPSAPTAASASSTAIPS 385
P P P S SPP+ SPS + P SPS P S S PS
Sbjct: 120 SPPSPAPPSP--SPPAPPSPSPPSPAPPLPPSPAPPSPSPPVPPSPSPPVPPS 170
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 241,170,924,377
Number of Sequences: 518415
Number of Extensions: 241170924377
Number of Successful Extensions: 1551573010
Number of sequences better than 0.0: 0
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