BLASTX 7.6.2
Query= UN75969 /QuerySize=714
(713 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6P1B1|XPP1_MOUSE Xaa-Pro aminopeptidase 1 OS=Mus musculus GN... 164 5e-040
sp|O54975|XPP1_RAT Xaa-Pro aminopeptidase 1 OS=Rattus norvegicus... 164 8e-040
sp|Q9NQW7|XPP1_HUMAN Xaa-Pro aminopeptidase 1 OS=Homo sapiens GN... 163 1e-039
sp|Q1JPJ2|XPP1_BOVIN Xaa-Pro aminopeptidase 1 OS=Bos taurus GN=X... 162 3e-039
sp|O43895|XPP2_HUMAN Xaa-Pro aminopeptidase 2 OS=Homo sapiens GN... 127 6e-029
sp|Q09795|YAA1_SCHPO Uncharacterized peptidase C22G7.01c OS=Schi... 127 1e-028
sp|Q95333|XPP2_PIG Xaa-Pro aminopeptidase 2 OS=Sus scrofa GN=XPN... 123 1e-027
sp|Q54G06|XPP1_DICDI Xaa-Pro aminopeptidase 1 OS=Dictyostelium d... 109 2e-023
sp|Q07825|XPP_YEAST Putative Xaa-Pro aminopeptidase OS=Saccharom... 62 3e-009
>sp|Q6P1B1|XPP1_MOUSE Xaa-Pro aminopeptidase 1 OS=Mus musculus GN=Xpnpep1 PE=2
SV=1
Length = 623
Score = 164 bits (415), Expect = 5e-040
Identities = 84/199 (42%), Positives = 121/199 (60%), Gaps = 5/199 (2%)
Frame = +3
Query: 84 SEILSSLRSLMATH---SPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALIT 254
SE+L LR M + P+ A ++PS D HQSEY++ D RR FVSGF GSAG A+IT
Sbjct: 7 SELLRQLRQAMRNSEYVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT 66
Query: 255 KNEARLWTDGRYFLQATQQLSNEWTLMRMG--EDPLVEVWMSDNLSEEANIGVDPWCVSV 428
+ A +WTDGRYFLQA +Q+ N WTLM+MG + P E W+ L E + +GVDP +
Sbjct: 67 EEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPT 126
Query: 429 DTANRWNKSFAKKNQNLVPTTTDLVDEVWQNRPPSHMSPVVVHPLEFSGRSVYDKLEELR 608
D + K +LVP +LVD++W +RP P++ L+++G S +K+ +LR
Sbjct: 127 DYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLR 186
Query: 609 SKLKQESARGYVIAALDEL 665
K+ + S +V+ ALDE+
Sbjct: 187 LKMAERSIAWFVVTALDEI 205
>sp|O54975|XPP1_RAT Xaa-Pro aminopeptidase 1 OS=Rattus norvegicus GN=Xpnpep1
PE=1 SV=1
Length = 623
Score = 164 bits (413), Expect = 8e-040
Identities = 84/199 (42%), Positives = 121/199 (60%), Gaps = 5/199 (2%)
Frame = +3
Query: 84 SEILSSLRSLMATH---SPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALIT 254
SE+L LR M + P+ A ++PS D HQSEY++ D RR FVSGF GSAG A+IT
Sbjct: 7 SELLRQLRQAMRNSECVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT 66
Query: 255 KNEARLWTDGRYFLQATQQLSNEWTLMRMG--EDPLVEVWMSDNLSEEANIGVDPWCVSV 428
+ A +WTDGRYFLQA +Q+ N WTLM+MG + P E W+ L E + +GVDP +
Sbjct: 67 EEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPT 126
Query: 429 DTANRWNKSFAKKNQNLVPTTTDLVDEVWQNRPPSHMSPVVVHPLEFSGRSVYDKLEELR 608
D + K +LVP +LVD++W +RP P++ L+++G S +K+ +LR
Sbjct: 127 DYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLR 186
Query: 609 SKLKQESARGYVIAALDEL 665
K+ + S +V+ ALDE+
Sbjct: 187 LKMAERSIVWFVVTALDEI 205
>sp|Q9NQW7|XPP1_HUMAN Xaa-Pro aminopeptidase 1 OS=Homo sapiens GN=XPNPEP1 PE=1
SV=3
Length = 623
Score = 163 bits (411), Expect = 1e-039
Identities = 82/199 (41%), Positives = 121/199 (60%), Gaps = 5/199 (2%)
Frame = +3
Query: 84 SEILSSLRSLMATH---SPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALIT 254
SE+L LR M + P+ A ++PS D HQSEY++ D RR FVSGF GSAG A+IT
Sbjct: 7 SELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT 66
Query: 255 KNEARLWTDGRYFLQATQQLSNEWTLMRMG--EDPLVEVWMSDNLSEEANIGVDPWCVSV 428
+ A +WTDGRYFLQA +Q+ + WTLM+MG + P E W+ L E + +GVDP +
Sbjct: 67 EEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPT 126
Query: 429 DTANRWNKSFAKKNQNLVPTTTDLVDEVWQNRPPSHMSPVVVHPLEFSGRSVYDKLEELR 608
D + K +L+P +LVD++W +RP P++ L+++G S DK+ +LR
Sbjct: 127 DYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKDKVADLR 186
Query: 609 SKLKQESARGYVIAALDEL 665
K+ + + +V+ ALDE+
Sbjct: 187 LKMAERNVMWFVVTALDEI 205
>sp|Q1JPJ2|XPP1_BOVIN Xaa-Pro aminopeptidase 1 OS=Bos taurus GN=XPNPEP1 PE=2
SV=1
Length = 623
Score = 162 bits (408), Expect = 3e-039
Identities = 81/199 (40%), Positives = 121/199 (60%), Gaps = 5/199 (2%)
Frame = +3
Query: 84 SEILSSLRSLMAT---HSPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALIT 254
SE+L LR M + P+ A ++PS D HQSEY++ D RR FVSGF GSAG A++T
Sbjct: 7 SELLRQLRQAMRNLEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIVT 66
Query: 255 KNEARLWTDGRYFLQATQQLSNEWTLMRMG--EDPLVEVWMSDNLSEEANIGVDPWCVSV 428
+ A +WTDGRYFLQA +Q+ + WTLM+MG + P E W+ L E + +GVDP +
Sbjct: 67 EEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPT 126
Query: 429 DTANRWNKSFAKKNQNLVPTTTDLVDEVWQNRPPSHMSPVVVHPLEFSGRSVYDKLEELR 608
D + K +L+P +LVD++W +RP P++ L+++G S DK+ +LR
Sbjct: 127 DYWKKMAKVLRSAGHHLIPVKDNLVDKIWTDRPERPCKPLITLGLDYTGISWKDKVADLR 186
Query: 609 SKLKQESARGYVIAALDEL 665
K+ + + +V+ ALDE+
Sbjct: 187 LKMAERNVVWFVVTALDEI 205
>sp|O43895|XPP2_HUMAN Xaa-Pro aminopeptidase 2 OS=Homo sapiens GN=XPNPEP2 PE=1
SV=3
Length = 674
Score = 127 bits (319), Expect = 6e-029
Identities = 72/216 (33%), Positives = 123/216 (56%), Gaps = 7/216 (3%)
Frame = +3
Query: 27 DI*T*NSNSLSLNRRISNMSEILSSLRSLMATHSPPLDALVVPSEDYHQSEYVSGRDKRR 206
D+ ++N L + N + L++LR M T + L A ++P D H +EY+ D+RR
Sbjct: 32 DVRNCSTNPPYLPVTVVNTTMSLTALRQQMQTQN--LSAYIIPGTDAHMNEYIGQHDERR 89
Query: 207 EFVSGFTGSAGLALITKNEARLWTDGRYFLQATQQLSNEWTLMR-MGEDPLVEVWMSDNL 383
+++GFTGSAG A++T +A +WTD RY+ QA +Q+ W L + +G P+V W+ +
Sbjct: 90 AWITGFTGSAGTAVVTMKKAAVWTDSRYWTQAERQMDCNWELHKEVGTTPIV-TWLLTEI 148
Query: 384 SEEANIGVDPWCVSVDTANRWNKSFAKKNQNLVPTTTDLVDEVW-QNRPPSHMSPVVVHP 560
+G DP+ +S+DT ++ + N+ LV TT+LVD VW RPP P+
Sbjct: 149 PAGGRVGFDPFLLSIDTWESYDLALQGSNRQLVSITTNLVDLVWGSERPPVPNQPIYALQ 208
Query: 561 LEFSGRSVYDKLEELRSKLK--QESARGYVIAALDE 662
F+G + +K+ +RS+++ Q+ +++AL+E
Sbjct: 209 EAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLSALEE 244
>sp|Q09795|YAA1_SCHPO Uncharacterized peptidase C22G7.01c OS=Schizosaccharomyces
pombe GN=SPAC22G7.01c PE=2 SV=4
Length = 598
Score = 127 bits (317), Expect = 1e-028
Identities = 76/195 (38%), Positives = 107/195 (54%), Gaps = 6/195 (3%)
Frame = +3
Query: 93 LSSLRSLMATHSPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALITKNEARL 272
L+ LR LM L VVPSED H SEY D RR F+SGF GSAG A+I + A L
Sbjct: 9 LNKLRELMKERGYTL--YVVPSEDAHSSEYTCDADARRAFISGFDGSAGCAVIGETSAAL 66
Query: 273 WTDGRYFLQATQQLSNEWTLMRMGED--PLVEVWMSDNLSEEANIGVDPWCVSVDTANRW 446
+TDGRYF QA+QQL WTLM+ G P E + + +G+D ++ A
Sbjct: 67 FTDGRYFNQASQQLDENWTLMKQGFTGVPTWEEYCTQMTKCNEKVGIDSSLITFPAAKAL 126
Query: 447 NKS-FAKKNQNLVPTTTDLVDEVW-QNRPPSHMSPVVVHPLEFSGRSVYDKLEELRSKLK 620
+S F K LV +LVD VW +RP + ++V ++++G V +KL LR +K
Sbjct: 127 RESLFLKSGAVLVGDHDNLVDIVWGASRPKEPLEKLIVQEIKYAGLGVDEKLHNLREAMK 186
Query: 621 QESARGYVIAALDEL 665
++ +V++ LDE+
Sbjct: 187 EQKIEAFVVSMLDEV 201
>sp|Q95333|XPP2_PIG Xaa-Pro aminopeptidase 2 OS=Sus scrofa GN=XPNPEP2 PE=1 SV=1
Length = 673
Score = 123 bits (308), Expect = 1e-027
Identities = 65/198 (32%), Positives = 112/198 (56%), Gaps = 5/198 (2%)
Frame = +3
Query: 78 NMSEILSSLRSLMATHSPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALITK 257
N + L++LR M T + L A ++P D H SEY+ D+RR +++GF GSAG+A++T+
Sbjct: 48 NTTAQLTALREQMLTQN--LSAYIIPDTDAHMSEYIGECDQRRAWITGFIGSAGIAVVTE 105
Query: 258 NEARLWTDGRYFLQATQQLSNEWTLMRMGEDPLVEVWMSDNLSEEANIGVDPWCVSVDTA 437
+A LWTD RY+ QA +Q+ W L + + W+ + +G DP+ S+D+
Sbjct: 106 RKAALWTDSRYWTQAERQMDCNWELHKEVSTGHIVTWLLTEIPVGGRVGFDPFLFSIDSW 165
Query: 438 NRWNKSFAKKNQNLVPTTTDLVDEVW-QNRPPSHMSPVVVHPLEFSGRSVYDKLEELRSK 614
++ + ++ LV T +LVD VW RPP +P+ F+G + +K+ +RS+
Sbjct: 166 ESYDVALQDADRELVSITVNLVDLVWGSERPPLPNAPIYALQEAFAGSTWQEKVSNIRSQ 225
Query: 615 LKQESAR--GYVIAALDE 662
+++ R +++ALDE
Sbjct: 226 MQKHHERPTAVLLSALDE 243
>sp|Q54G06|XPP1_DICDI Xaa-Pro aminopeptidase 1 OS=Dictyostelium discoideum
GN=xpnpep1 PE=3 SV=1
Length = 627
Score = 109 bits (272), Expect = 2e-023
Identities = 53/117 (45%), Positives = 80/117 (68%), Gaps = 4/117 (3%)
Frame = +3
Query: 81 MSEILSSLRSLMATHSPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFTGSAGLALITKN 260
+S+ + LR+ M S L A +VPSED HQSEY+ +DKRRE++SGF+GSAG +IT +
Sbjct: 22 ISKKVEKLRTFMKDQS--LSAYIVPSEDAHQSEYICVKDKRREYISGFSGSAGCVVITLD 79
Query: 261 EARLWTDGRYFLQATQQLSNEWTLM--RMGEDPLVEVWMSDNLSEEANIGVDPWCVS 425
LWTDGRY+LQA ++L + W +M R+ +P ++ W+ NL++E +G+D +S
Sbjct: 80 NQLLWTDGRYWLQAEKELESNWKIMKDRVVGEPTIQDWLLSNLNKENKVGIDSRLIS 136
>sp|Q07825|XPP_YEAST Putative Xaa-Pro aminopeptidase OS=Saccharomyces cerevisiae
GN=YLL029W PE=1 SV=1
Length = 749
Score = 62 bits (149), Expect = 3e-009
Identities = 36/71 (50%), Positives = 46/71 (64%), Gaps = 2/71 (2%)
Frame = +3
Query: 48 NSLSLNRRISNMSEILSSLRSLMATHSPPLDALVVPSEDYHQSEYVSGRDKRREFVSGFT 227
+SL R N ++ L LR M H L +VPS D HQSEYVS RD+RR F+SGF+
Sbjct: 94 DSLCAVNREVNTTDRLLKLRQEMKKHD--LCCYIVPSCDEHQSEYVSLRDQRRAFISGFS 151
Query: 228 GSAGLALITKN 260
GSAG+A IT++
Sbjct: 152 GSAGVACITRD 162
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 246,587,781,645
Number of Sequences: 518415
Number of Extensions: 246587781645
Number of Successful Extensions: 1601389213
Number of sequences better than 0.0: 0
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