BLASTX 7.6.2
Query= UN77493 /QuerySize=697
(696 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 95 4e-019
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 94 1e-018
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 91 6e-018
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 91 8e-018
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 90 1e-017
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 89 2e-017
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 89 3e-017
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 88 5e-017
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 87 1e-016
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 86 2e-016
sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xeno... 84 1e-015
sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xeno... 82 2e-015
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 79 2e-014
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 79 3e-014
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 78 4e-014
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 77 7e-014
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 77 1e-013
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 71 7e-012
sp|Q9DBU5|RNF6_MOUSE E3 ubiquitin-protein ligase RNF6 OS=Mus mus... 65 4e-010
sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabi... 65 4e-010
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 95 bits (234), Expect = 4e-019
Identities = 50/112 (44%), Positives = 64/112 (57%), Gaps = 10/112 (8%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA KE +++L TV + EE L+C VC DD+ +G R++PC H FH C++PWL
Sbjct: 204 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWL 263
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGS-GNSHP 350
E H SCPVCR L T T +P G G S S +SS S GN +P
Sbjct: 264 EQHDSCPVCRKSLTGQNTAT------DPPGLAGVSFSSSSSSSSSSPGNENP 309
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 94 bits (231), Expect = 1e-018
Identities = 48/110 (43%), Positives = 61/110 (55%), Gaps = 9/110 (8%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA KE +++L TV + EE L+C VC DD+ +G R++PC H FH C++PWL
Sbjct: 201 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWL 260
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGSGNSH 353
E H SCPVCR L T T P G G S S +SS S S+
Sbjct: 261 EQHDSCPVCRKSLTGQNTAT------NPPGLTGVSFSSSSSSSSSSSPSN 304
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 91 bits (224), Expect = 6e-018
Identities = 46/110 (41%), Positives = 60/110 (54%), Gaps = 9/110 (8%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA KE +++L TV + EE L+C VC +D+ +G R++PC H FH C++PWL
Sbjct: 203 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWL 262
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGSGNSH 353
E H SCPVCR L T T P G G S +SS S S+
Sbjct: 263 EQHDSCPVCRKSLTGQNTAT------NPPGLTGVGFSSSSSSSSSSSPSN 306
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 91 bits (223), Expect = 8e-018
Identities = 43/109 (39%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA E +++L T++I EE L+C VC +D+ +G R++PC H FH DC++PWL
Sbjct: 200 GPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWL 259
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGSGNS 356
E H +CPVCR L T T E + + S TS NS
Sbjct: 260 EQHDTCPVCRKSLSGQNTATNPPGLSEMTFSSSSTSSSSSTSPTDENNS 308
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 90 bits (222), Expect = 1e-017
Identities = 42/109 (38%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA E +++L T++I EE L+C VC +D+ +G R++PC H FH DC++PWL
Sbjct: 199 GPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 258
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGSGNS 356
E H +CPVCR L T T E + + S TS N+
Sbjct: 259 EQHDTCPVCRKSLSGQNTATNPPGLTEMTFSSSSTSSSSSTSPTDENNA 307
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 89 bits (220), Expect = 2e-017
Identities = 39/91 (42%), Positives = 55/91 (60%), Gaps = 3/91 (3%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA KE + SL TV + +E L+C VC +D+ + E R++PC H FH C++PWL
Sbjct: 200 GPPPADKEKITSLPTVTVTQEQVDMGLECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWL 259
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGN 410
ELH +CPVCR L +++ + TE N
Sbjct: 260 ELHDTCPVCRKSLNGEDSTRQSQSTEASASN 290
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 89 bits (218), Expect = 3e-017
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 9/106 (8%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA + +++L T++I EE L+C VC +D+ +G R++PC H FH DC++PWL
Sbjct: 200 GPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 259
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGNDGGSVFSFFTSSQGS 365
E H +CPVCR L T T P G + S TSS S
Sbjct: 260 EQHDTCPVCRKSLSGQNTAT------NPPGLTDMTFSSSSTSSSSS 299
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 88 bits (216), Expect = 5e-017
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 6/93 (6%)
Frame = -3
Query: 667 PPALKEAVESLSTVKIQEE------DTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPW 506
PPA KE VE L + EE +C +C ++ VIG + +E+PCKH FH CL PW
Sbjct: 201 PPASKEVVEKLPVIIFTEELLKKFGAEAECCICKENLVIGDKMQELPCKHTFHPPCLKPW 260
Query: 505 LELHCSCPVCRYELPSDETKTEFARTEEPNGND 407
L+ H SCP+CR+ELP+D+ K E + E +
Sbjct: 261 LDEHNSCPICRHELPTDDQKYENWKEREKEAEE 293
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 87 bits (213), Expect = 1e-016
Identities = 37/86 (43%), Positives = 56/86 (65%), Gaps = 3/86 (3%)
Frame = -3
Query: 679 RYGTPPALKEAVESLSTVKI---QEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLP 509
R G PPA K A+E+L T ++ + E + C+VC D V+G +++PC H +HGDC++P
Sbjct: 227 RRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVP 286
Query: 508 WLELHCSCPVCRYELPSDETKTEFAR 431
WL SCPVCR++L +D+ + E R
Sbjct: 287 WLGTRNSCPVCRFQLETDDAEYEEER 312
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 86 bits (212), Expect = 2e-016
Identities = 37/91 (40%), Positives = 55/91 (60%), Gaps = 3/91 (3%)
Frame = -3
Query: 673 GTPPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWL 503
G PPA KE + SL TV + +E L+C VC +D+ + + R++PC H FH C++PWL
Sbjct: 201 GPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWL 260
Query: 502 ELHCSCPVCRYELPSDETKTEFARTEEPNGN 410
ELH +CPVCR L +++ + +E N
Sbjct: 261 ELHDTCPVCRKSLNGEDSTRQTQSSEASASN 291
>sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xenopus tropicalis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 84 bits (205), Expect = 1e-015
Identities = 39/85 (45%), Positives = 54/85 (63%), Gaps = 3/85 (3%)
Frame = -3
Query: 667 PPALKEAVESLSTVKI---QEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLEL 497
PPA K+ VESL V + Q + L+C VCL +F G R++PC+H FH C+LPWL
Sbjct: 53 PPAAKKVVESLPKVTVTPEQADAALKCPVCLLEFEEGETVRQLPCEHLFHSSCILPWLGK 112
Query: 496 HCSCPVCRYELPSDETKTEFARTEE 422
SCP+CR+ELP+D + E + E+
Sbjct: 113 TNSCPLCRHELPTDSPEYEEYKQEK 137
>sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xenopus laevis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 82 bits (202), Expect = 2e-015
Identities = 42/90 (46%), Positives = 56/90 (62%), Gaps = 8/90 (8%)
Frame = -3
Query: 667 PPALKEAVESLSTVKI---QEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLEL 497
PPA K+ VESL V + Q + L+C VCL +F G R++PC+H FH C+LPWL
Sbjct: 53 PPASKKVVESLPKVTVTPEQADAALKCPVCLLEFEEGETVRQLPCEHLFHSACILPWLGK 112
Query: 496 HCSCPVCRYELPSD-----ETKTEFARTEE 422
SCP+CR+ELP+D E K E AR ++
Sbjct: 113 TNSCPLCRHELPTDSPDYEEFKQEKARRQQ 142
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 79 bits (194), Expect = 2e-014
Identities = 41/86 (47%), Positives = 50/86 (58%), Gaps = 4/86 (4%)
Frame = -3
Query: 667 PPALKEAVESLSTVKIQEEDT---LQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLEL 497
PPA K V+SL V I E ++C VCL +F REMPCKH FH C+LPWL
Sbjct: 53 PPAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWLNK 112
Query: 496 HCSCPVCRYELPSDETK-TEFARTEE 422
SCP+CR ELP+D EF + +E
Sbjct: 113 TNSCPLCRLELPTDNADYEEFKKDKE 138
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 79 bits (193), Expect = 3e-014
Identities = 39/83 (46%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -3
Query: 667 PPALKEAVESLSTVKIQ-EEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELHC 491
PPA K VE+L I+ + L+C VCL +F A EMPC H FH C+LPWL
Sbjct: 52 PPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTN 111
Query: 490 SCPVCRYELPSDETKTEFARTEE 422
SCP+CRYELP+D+ E R ++
Sbjct: 112 SCPLCRYELPTDDDTYEEHRRDK 134
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 78 bits (191), Expect = 4e-014
Identities = 38/77 (49%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = -3
Query: 667 PPALKEAVESLSTVKIQ-EEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELHC 491
PPA K AVE+L I+ + L+C VCL +F A EMPC H FH +C+LPWL
Sbjct: 52 PPAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTN 111
Query: 490 SCPVCRYELPSDETKTE 440
SCP+CR+ELP+D+ E
Sbjct: 112 SCPLCRHELPTDDDTYE 128
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 77 bits (189), Expect = 7e-014
Identities = 38/77 (49%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
Frame = -3
Query: 667 PPALKEAVESL-STVKIQEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELHC 491
PPA K VESL TV + L+C VCL +F EMPC H FH +C+LPWL
Sbjct: 64 PPAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTN 123
Query: 490 SCPVCRYELPSDETKTE 440
SCP+CR+ELP+D+ E
Sbjct: 124 SCPLCRHELPTDDDSYE 140
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 77 bits (187), Expect = 1e-013
Identities = 38/77 (49%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
Frame = -3
Query: 667 PPALKEAVESL-STVKIQEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELHC 491
PPA K VESL TV + L+C VCL +F EMPC H FH +C+LPWL
Sbjct: 64 PPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTN 123
Query: 490 SCPVCRYELPSDETKTE 440
SCP+CR+ELP+D+ E
Sbjct: 124 SCPLCRHELPTDDDSYE 140
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 71 bits (172), Expect = 7e-012
Identities = 36/82 (43%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = -3
Query: 667 PPALKEAVESL---STVKIQEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLEL 497
P A K A+ L VK E L+CSVC + G + R +PCKH+FH +C+L WL+
Sbjct: 44 PEASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKK 103
Query: 496 HCSCPVCRYELPSDETKTEFAR 431
SCP+CRYEL +D+ E R
Sbjct: 104 TNSCPLCRYELETDDPVYEELR 125
>sp|Q9DBU5|RNF6_MOUSE E3 ubiquitin-protein ligase RNF6 OS=Mus musculus GN=Rnf6
PE=1 SV=1
Length = 667
Score = 65 bits (157), Expect = 4e-010
Identities = 29/67 (43%), Positives = 44/67 (65%), Gaps = 7/67 (10%)
Frame = -3
Query: 655 KEAVESLSTVKIQEEDTLQ------CSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELH 494
KE +++LST + E+D + CSVC+ D+V G + R++PC H+FH C+ WL +
Sbjct: 590 KEQIDNLST-RSYEQDGVDSELGKVCSVCISDYVAGNKLRQLPCLHEFHIHCIDRWLSEN 648
Query: 493 CSCPVCR 473
C+CPVCR
Sbjct: 649 CTCPVCR 655
>sp|Q9M2S6|SDIR1_ARATH E3 ubiquitin-protein ligase SDIR1 OS=Arabidopsis thaliana
GN=SDIR1 PE=1 SV=1
Length = 273
Score = 65 bits (157), Expect = 4e-010
Identities = 27/71 (38%), Positives = 41/71 (57%)
Frame = -3
Query: 670 TPPALKEAVESLSTVKIQEEDTLQCSVCLDDFVIGMEAREMPCKHKFHGDCLLPWLELHC 491
T + ++ ++S + K ED L CSVCL+ +G R +PC H+FH C+ PWL
Sbjct: 187 TSSSAEKMLDSANESKKGTEDELTCSVCLEQVTVGEIVRTLPCLHQFHAGCIDPWLRQQG 246
Query: 490 SCPVCRYELPS 458
+CPVC++ S
Sbjct: 247 TCPVCKFRAHS 257
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 249,981,154,389
Number of Sequences: 518415
Number of Extensions: 249981154389
Number of Successful Extensions: 1620631332
Number of sequences better than 0.0: 0
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